SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 11/MAY/2005
Date Updated: 12/MAR/2004
Version 1.4
According to 91/155/EEC
1 - Product and Company Information
Product Name POTASSIUM IODIDE, 99.99+%
Product Number 204102
Company Sigma-Aldrich Pty, Ltd
Unit 2, 14 Anella Avenue
Castle Hill NSW 1765
Australia
Technical Phone # +61 2 9841 0555
Fax +61 2 9841 0500
Emergency Phone # +61 2 9841 0566
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
POTASSIUM IODIDE 7681-11-0 231-659-4 None
Formula KI
Molecular Weight 166.01 AMU
Synonyms K1-N * Knollide * Potide
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Not hazardous according to Directive 67/548/EC.
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If breathing becomes difficult,
call a physician.
AFTER SKIN CONTACT
In case of contact, immediately wash skin with soap and copious
amounts of water.
AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.
SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Exercise appropriate precautions to minimize direct contact with
skin or eyes and prevent inhalation of dust.
METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Avoid
raising dust. Ventilate area and wash spill site after material
pickup is complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Avoid inhalation. Avoid contact
with eyes, skin, and clothing. Avoid prolonged or repeated
exposure.
STORAGE
Conditions of Storage: Keep tightly closed. Store under argon.
Store in a cool dry place.
SPECIAL REQUIREMENTS: Air, light, and moisture sensitive. Store
under inert gas.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Safety shower and eye bath. Mechanical exhaust required.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling.
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Wear dust mask.
Hand Protection: Protective gloves.
Eye Protection: Chemical safety goggles.
9 - Physical and Chemical Properties
Appearance Physical State: Solid
Color: White
Form: Fine crystals
Property Value At Temperature or Pressure
pH 6-9
BP/BP Range 1,330 掳C
MP/MP Range 681 掳C
Flash Point N/A
Flammability N/A
Autoignition Temp N/A
Oxidizing Properties N/A
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Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure 1 mmHg 745 掳C
SG/Density 3.13 g/cm3
Partition Coefficient N/A
Viscosity N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density 1,700 kg/l
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility Solubility in Water:1 M in H2O, 20掳C
complete, colorless
10 - Stability and Reactivity
STABILITY
Stable: Stable.
Conditions of Instability: May decompose on exposure to light. May
decompose on exposure to air and moisture.
Conditions to Avoid: Tin.
Materials to Avoid: Strong reducing agents, Nickel, Strong acids,
and their alloys, Steel, Aluminum, Alkali metals, Brass,
Magnesium, Zinc, Cadmium, Copper.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Hydrogen iodide, Potassium
oxides.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
RTECS NUMBER: TT2975000
SENSITIZATION
Sensitization: Prolonged or repeated exposure may cause allergic
reactions in certain sensitive individuals.
SIGNS AND SYMPTOMS OF EXPOSURE
Prolonged exposure to iodides may produce iodism in sensitive
individuals. Symptoms of exposure include: skin rash, running
nose, headache and irritation of the mucous membrane. For severe
cases the skin may show pimples, boils, hives, blisters and
black and blue spots. Iodides are readily diffused across the
placenta. Neonatal deaths from respiratory distress secondary to
goiter have been reported. Iodides have been known to cause
drug-induced fevers, which are usually of short duration.
ROUTE OF EXPOSURE
Skin Contact: May cause skin irritation.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: May cause eye irritation.
Inhalation: May be harmful if inhaled. Material may be
irritating to mucous membranes and upper respiratory tract.
Ingestion: May be harmful if swallowed.
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TARGET ORGAN INFORMATION
Thyroid.
CHRONIC EXPOSURE - MUTAGEN
Rat
500 MG/KG
Cell Type: Ascites tumor
Cytogenetic analysis
CHRONIC EXPOSURE - TERATOGEN
Result: Exposure to excessive amounts of iodine during pregnancy
is capable of producing fetal hypothyroidism. Iodine-containing
drugs have been associated with fetal goiter.
Species: Woman
Dose: 2700 MG/KG
Route of Application: Oral
Exposure Time: (1-39W PREG)
Result: Specific Developmental Abnormalities: Endocrine system.
Species: Woman
Dose: 3240 MG/KG
Route of Application: Oral
Exposure Time: (1-39W PREG)
Result: Specific Developmental Abnormalities: Endocrine system.
Effects on Newborn: Other neonatal measures or effects. Effects
on Newborn: Physical.
CHRONIC EXPOSURE - REPRODUCTIVE HAZARD
Species: Rat
Dose: 10530 MG/KG
Route of Application: Oral
Exposure Time: (1-9D PREG)
Result: Effects on Fertility: Pre-implantation mortality (e.g.,
reduction in number of implants per female; total number of
implants per corpora lutea). Effects on Embryo or Fetus:
Fetotoxicity (except death, e.g., stunted fetus).
Species: Rat
Dose: 822 MG/KG
Route of Application: Oral
Exposure Time: (2W MALE/2W PRE-13D POST)
Result: Effects on Newborn: Behavioral.
Species: Rat
Dose: 922 MG/KG
Route of Application: Oral
Exposure Time: (2W MALE/2W PRE-21D POST)
Result: Effects on Newborn: Viability index (e.g., # alive at
day 4 per # born alive).
Species: Rat
Dose: 300 MG/KG
Route of Application: Oral
Exposure Time: (9D PREG)
Result: Effects on Fertility: Post-implantation mortality (e.g.,
dead and/or resorbed implants per total number of implants).
Effects on Embryo or Fetus: Fetotoxicity (except death, e.g.,
stunted fetus). Effects on Embryo or Fetus: Fetal death.
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Species: Hamster
Dose: 3600 MG/KG
Route of Application: Oral
Exposure Time: (5-16D PREG)
Result: Effects on Newborn: Growth statistics (e.g., reduced
weight gain).
Species: Mammal
Dose: 294 MG/KG
Route of Application: Oral
Exposure Time: (30D PRE)
Result: Maternal Effects: Parturition.
Species: Mammal
Dose: 1177 MG/KG
Route of Application: Oral
Exposure Time: (30D PRE)
Result: Effects on Newborn: Growth statistics (e.g., reduced
weight gain).
12 - Ecological Information
No data available.
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
environmental regulations.
14 - Transport Information
RID/ADR
Non-hazardous for road transport.
IMDG
Non-hazardous for sea transport.
IATA
Non-hazardous for air transport.
15 - Regulatory Information
Not hazardous according to Directive 67/548/EC.
COUNTRY SPECIFIC INFORMATION
Germany
WGK: 1
SWITZERLAND
SWISS POISON CLASS: 4
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
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information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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