SIGMA-ALDRICH



                         Material Safety Data Sheet



                                                 Date Printed: 16/NOV/2005

                                                 Date Updated: 19/SEP/2005

                                                               Version 1.3

                                                   According to 91/155/EEC





1 - Product and Company Information



Product Name                   IODINE, VOLUMETRIC STANDARD, 0.1N

                               SOLUTI ON IN WATER

Product Number                 318981



Company                        Sigma-Aldrich Pty. Ltd.

                               12 Anella Avenue

                               Castle Hill NSW 2154

                               Australia

Technical Phone #              +61 2 9841 0555 (1800 800 097)

Fax                            +61 2 9841 0500 (1800 800 096)

Emergency Phone #              +44 8701906777 (1800 448 465)



2 - Composition/Information on Ingredients



Product Name                         CAS #        EC no       Annex I

                                                              Index Number

IODINE SOLUTIONS 0.05M (0.1N)        None         None        None



Ingredient Name            Percent   CAS #        EC no       Annex I

                                                              Index Number

IODINE                     >= 1      7553-56-2    231-442-4   053-001-00-3

                           <= 1.5

Symbols: Xn-N

R-Phrases: 20/21-50

   Harmful by inhalation and in contact with skin. Very toxic to

   aquatic organisms.



WATER                      >= 98     7732-18-5    231-791-2   None



3 - Hazards Identification





SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT

   Not hazardous according to Directive 67/548/EEC.



4 - First Aid Measures



AFTER INHALATION

   If inhaled, remove to fresh air. If breathing becomes difficult,

   call a physician.



AFTER SKIN CONTACT

   In case of contact, immediately wash skin with soap and copious

   amounts of water.



AFTER EYE CONTACT

   In case of contact with eyes, flush with copious amounts of

   water for at least 15 minutes. Assure adequate flushing by

   separating the eyelids with fingers. Call a physician.

AFTER INGESTION

   If swallowed, wash out mouth with water provided person is

   conscious. Call a physician.



5 - Fire Fighting Measures



EXTINGUISHING MEDIA

   Suitable: Noncombustible. Use extinguishing media appropriate to

   surrounding fire conditions.



SPECIAL RISKS

   Specific Hazard(s): Emits toxic fumes under fire conditions.



SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS

   Wear self-contained breathing apparatus and protective clothing

   to prevent contact with skin and eyes.



6 - Accidental Release Measures



METHODS FOR CLEANING UP

   Absorb on sand or vermiculite and place in closed containers for

   disposal. Ventilate area and wash spill site after material

   pickup is complete.



7 - Handling and Storage



HANDLING

   Directions for Safe Handling: Avoid inhalation. Avoid contact

   with eyes, skin, and clothing. Avoid prolonged or repeated

   exposure.



STORAGE

   Conditions of Storage: Keep tightly closed.



8 - Exposure Controls / Personal Protection



ENGINEERING CONTROLS

   Safety shower and eye bath. Mechanical exhaust required.



GENERAL HYGIENE MEASURES

   Wash thoroughly after handling.



PERSONAL PROTECTIVE EQUIPMENT

   Hand Protection: Protective gloves.

   Eye Protection: Chemical safety goggles.



9 - Physical and Chemical Properties



Appearance              Physical State: Liquid



Property                Value                 At Temperature or Pressure



pH                      N/A

BP/BP Range             N/A

MP/MP Range             N/A

Flash Point             N/A

Flammability            N/A

Autoignition Temp       N/A

Oxidizing Properties    N/A

Explosive Properties    N/A

Explosion Limits        N/A

Vapor Pressure          N/A





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SG/Density              N/A

Partition Coefficient   N/A

Viscosity               N/A

Vapor Density           N/A

Saturated Vapor Conc.   N/A

Evaporation Rate        N/A

Bulk Density            N/A

Decomposition Temp.     N/A

Solvent Content         N/A

Water Content           N/A

Surface Tension         N/A

Conductivity            N/A

Miscellaneous Data      N/A

Solubility              N/A



10 - Stability and Reactivity



STABILITY

   Stable: Stable.

   Materials to Avoid: Strong oxidizing agents.



HAZARDOUS DECOMPOSITION PRODUCTS

   Hazardous Decomposition Products: Potassium oxides, Iodine.



HAZARDOUS POLYMERIZATION

   Hazardous Polymerization: Will not occur



11 - Toxicological Information



SENSITIZATION

   Sensitization: Prolonged or repeated exposure may cause allergic

   reactions in certain sensitive individuals.



SIGNS AND SYMPTOMS OF EXPOSURE

   Prolonged exposure to iodides may produce iodism in sensitive

   individuals. Symptoms of exposure include: skin rash, running

   nose, headache and irritation of the mucous membrane. For severe

   cases the skin may show pimples, boils, hives, blisters and

   black and blue spots. Iodides are readily diffused across the

   placenta. Neonatal deaths from respiratory distress secondary to

   goiter have been reported. Iodides have been known to cause

   drug-induced fevers, which are usually of short duration.

   Symptoms of exposure may include burning sensation, coughing,

   wheezing, laryngitis, shortness of breath, headache, nausea, and

   vomiting.



ROUTE OF EXPOSURE

   Skin Contact: May cause skin irritation.

   Skin Absorption: May be harmful if absorbed through the skin.

   Eye Contact: May cause eye irritation.

   Inhalation: May be harmful if inhaled. Material may be

   irritating to mucous membranes and upper respiratory tract.

   Ingestion: May be harmful if swallowed.



TARGET ORGAN INFORMATION

   Thyroid. Kidneys. Endocrine system.



CHRONIC EXPOSURE - TERATOGEN

   Result: Exposure to excessive amounts of iodine during pregnancy

   is capable of producing fetal hypothyroidism. Iodine-containing

   drugs have been associated with fetal goiter.







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12 - Ecological Information



No data available.



13 - Disposal Considerations



SUBSTANCE DISPOSAL

   Contact a licensed professional waste disposal service to dispose

   of this material. Dissolve or mix the material with a combustible

   solvent and burn in a chemical incinerator equipped with an

   afterburner and scrubber. Observe all federal, state, and local

   environmental regulations.



14 - Transport Information



RID/ADR

   Non-hazardous for road transport.



IMDG

   Non-hazardous for sea transport.



IATA

   Non-hazardous for air transport.



15 - Regulatory Information



Not hazardous according to Directive 67/548/EEC.



COUNTRY SPECIFIC INFORMATION



Germany

   WGK: No hazard to waters.



16 - Other Information



WARRANTY

   The above information is believed to be correct but does not

   purport to be all inclusive and shall be used only as a guide. The

   information in this document is based on the present state of our

   knowledge and is applicable to the product with regard to

   appropriate safety precautions. It does not represent any

   guarantee of the properties of the product. Sigma-Aldrich Inc.,

   shall not be held liable for any damage resulting from handling or

   from contact with the above product. See reverse side of invoice

   or packing slip for additional terms and conditions of sale.

   Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited

   paper copies for internal use only.



DISCLAIMER

   For R&D use only. Not for drug, household or other uses.









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