TOKU-E COMPANY
MATERIAL SAFETY DATA SHEET
EMERGENCY PHONE (USA only): +1-800-535-5053 INF.: +86-21-5206 9530
. Substance identification
Ampicillin Trihydrate semi synthetic from Penicillin
. Composition/ information on ingredients
CAS No.: 7177-48-2
FW: C16H19N3O4S?H2O
. Hazard identification
Label precautionary statements
Harmful
Irritating to eyes, respiratory system and skin. May cause sensitization by
inhalation and skin contact.
Target organ(s): Blood
In case of accident or if you feel unwell, seek medical advice immediately (show
label when possible). Wear suitable protective clothing, gloves and eye/ face
protection.
. First-aid measures
In case of contact, immediately flush eyes or skin with copious amounts of water
at least 15minutes while removing contaminated clothing and shoes. Assure
adequate flushing of eyes by separating eyelids with fingers. If inhaled, remove
to fresh air. If breathing is difficult, call a physician. If swallowed, wash out mouth
with water (provided person is conscious). Call a physician immediately. Wash
all contaminated clothing before reuse.
. Fire extinguishing measures
Extinguishing media: Water spray. Carbon dioxide, dry chemical powder or
appropriate foam.
Wear self-contained breathing apparatus and protective clothing to prevent
contact with eyes and skin.
Unusual fire and explosion hazards:
Emits toxic fumes under fire conditions.
. Accidental release measures
Wear respirator, chemical safety goggles, rubber boots and heavy rubber gloves.
Sweep up, avoid raising dust, place in a bag and hold for waste disposal.
Ventilate area and wash spill site after material pickup is complete.
MSDS Ampicillin Trihydrate 1/3
. Handling and storage
Wear government approved respirator, chemical resistant gloves, safety goggles,
and all other protective clothing. Mechanical exhaust required. Avoid contact with
eyes, skin, and clothing. Avoid breathing dust. Avoid prolonged or repeated
exposure. Wash thoroughly after handling.
Store at 2 -8癈. Store under argon. Keep tightly closed.
Store under inert gas. Air sensitive.
. Physical properties
Appearance: White solid
PH: N/A
Melting point: 200癈
Solubility: 50 MG/ML H2O clear, very faintly yellow
. Stability and reactivity
Stable. Avoid oxidizing agents. Sensitive to air.
Hazardous combustion or decomposition products thermal decomposition
may produce carbon monoxide, carbon dioxide, nitrogen oxides and sulfur
oxides.
Hazardous polymerization will not occur.
. Toxicological information
May cause skin irritation. May be harmful if absorbed through the skin. May
cause eye irritation. May be harmful if inhaled. Material may be irritating to
mucous membranes and upper respiratory tract. May be harmful if swallowed.
Signs and symptoms of exposure: To the best of our knowledge, the chemical,
physical, and toxicological properties have not been thoroughly investigated.
Sensitization: May cause allergic reaction. There are reports of serious and
sometimes fatal hypersensitivity (anaphylactic) reactions occurring in people
receiving penicillin therapy by the parenteral route although it has also occurred
via oral administration. These reaction usually occur in individuals who have a
history of sensitivity to multiple allergens, asthma, hay fever or urticaria.
Ingestion has resulted in nausea, vomiting, diarrhea, glossitis, and stomatitis,
enter colitis, pseudomembranous colitis. Hypersensitivity reactions:
erythematous maculopapular rashes, erythema multiforme, urticaria and
exfoliative dermatis.
Target organ(s): Blood
Toxicity data:
Oral Rat LD50: 10000 MG/KG
Oral Mouse LD50: 15200 MG/KG
IARC list: Rating Group 3
NTP Carcinogen list: Rating: equivocal evidence Species: Rat Route: Gavage
Chronic exposure: This product is or contains that is not classifiable as to its
carcinogen city based on its IARC, ACGIH, NIP, or EPA classification.
MSDS Ampicillin Trihydrate 2/3
Only selected registry of toxic effects of chemical substances (RTECS) data is
presented here. See actual entry in trees for complete information.
.Ecological information: Data not yet available.
. Disposal considerations
Contact a licensed professional waste disposal service to dispose of this material.
Dissolve or mix the material with a combustible solvent and burn in a chemical
incinerator equipped with an afterburner and scrubber. Observe all federal, state
and local environmental regulations.
. Transport information:
This product is considered to be non-hazardous for transport.
Non-hazardous for air transport.
. Regulatory information
US information
Harmful.
Irritating to eyes, respiratory system and skin. May cause sensitization by
inhalation and skin contact.
Do not breathe dust. In case of contact with eyes, rinse immediately with plenty
of water and seek medical advice. Wear suitable protective clothing and gloves.
Target organ(s): Blood.
SARA listed: No
European information:
Harmful
R: 36/37/38 42/43
Irritating to eyes, respiratory system and skin. May cause sensitization by
inhalation and skin contact.
S: 22 26 36/37
Do not breathe dust. In case of contact with eyes, rinse immediately with plenty
of water and seek medical advice. Wear suitable protective clothing and gloves.
Canada information
This product has been classified in accordance with the hazard criteria of the
CPR, and the MSDS contains all the information required by the CPR.
DSL: No
NDSL: No
. Other Information
The information and recommendations set forth herein are believed to be
completed and faithful. However, it is the user's responsibility to determine the
suitability for his/ her purpose prior to use. Toku-E Company assumes no
additional liability and responsibility resulting from use and/ or reliance on this
information.
MSDS Ampicillin Trihydrate 3/3
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