MATERIAL SAFETY DATA SHEET
ERA A Waters Company
SECTION 1: PRODUCT AND COMPANY IDENTIFICATION
MANUFACTURER: ERA (Environmental Resource Associates) BUSINESS PHONE: 303-431-8454
6000 W. 54th Avenue
ADDRESS: FAX: 303-421-0159 EMAIL: info@eraqc.com
Arvada, CO, 80002 U.S.A. CHEMICAL EMERGENCY PHONE: 352-535-5053 (INFOTRAC)
Waters Standard Fraction Lynx
Product Name(s):
716000261
Catalog / Part Number(s):
MSDS Creation Date: February 8, 2008
Revision Date: September 9, 2009 MSDS Reference Number: 7160000261
SECTION 2: HAZARDS IDENTIFICATION
Not hazardous according to Directive 199/45/EC or 67/548/EEC. Use only as directed and in accordance with good lab practices.
SECTION 3: COMPOSITION/INFORMATION ON INGREDIENTS
EU
EXPOSURE LIMITS LABEL
%
CHEMICAL INGREDIENT NAME CAS EC BY HAZARD
NUMBER NUMBER WT. OSHA ACGIH LABEL
Diphenhydramine hydrochloride
(Standards 1 & 5) 147-24-0 205-687-2 100 NA NA NA
Oxybutynin chloride (Standards 2 & 6) 1508-65-2 216-139-7 100 NA NA NA
Terfenadine (Standards 3 & 7) 50679-08-8 256-710-8 100 NA NA NA
Coumarin 314 (Standard 4) 55804-66-5 259-825-1 100 NA NA NA
Notes: This kit contain 50-100 mg of the above listed chemicals in powder form packaged in small vials used for verification in Mass
Spectroscopy (MS). Considered Non-Hazardous under OSHA 1910.1200 (HazCom) as product contains no known or potential carcinogens in
excess of 0.1% of the composition nor any other hazardous chemical in excess of 1% of the composition.
Material Use: Analytical reagent or certified reference material used in laboratories. Uses also include research and development.
SECTION 4: FIRST-AID MEASURES
Inhalation: Remove to fresh air.
Skin Contact: Flush with water.
Eye Contact: Immediately flush with water for a minimum of 15 minutes.
Ingestion: Get medical attention
After following first aid measures, seek medical attention.
SECTION 5: FIRE-FIGHTING MEASURES
Flammable Properties: Not flammable.
Extinguishing Media: Dry chemical, carbon dioxide or appropriate foam.
Unique Aspects Contributing To a Fire: None.
Special Fire Fighting Procedures: None. Note: As in any fire, wear self-contained breathing apparatus, and full protective gear.
SECTION 6: ACCIDENTAL RELEASE MEASURES
Due to small quantities involved, spills or leaks should not pose a significant problem. Place wastes into closed containers for proper
disposal.
SECTION 7: HANDLING AND STORAGE
Handle in accordance with good laboratory practices. Store in a dry well-ventilated place. This product is intended for use only by people
trained in the safety and handling of chemicals and laboratory preparations.
SECTION 8: EXPOSURE CONTROLS/PERSONAL PROTECTION
Handle in accordance with good laboratory practices. Wash thoroughly after handling.
Respiratory Protection: Not normally needed. If exposure limits are exceeded, use approved respirator.
Eye Protection: Safety glasses with side shields or safety goggles
Skin Protection: Neoprene or other chemical resistant gloves.
Engineering Controls: Not normally needed. If exposure limits are exceeded, work in a fume hood.
MSDS Reference #: 716000261 PAGE 1 of 2
MATERIAL SAFETY DATA SHEET
ERA A Waters Company
SECTION 9: PHYSICAL AND CHEMICAL PROPERTIES
DATA FOR MATRIX:
Appearance: Powder Specific Gravity: NA Melting Point: NA
Physical State: Solid Flash Point: NA Vapor Pressure: NA
Odor: NA Explosion Limits: NA Vapor Density (air=1): NA
pH: NA Boiling Point: NA Solubility in Water: NA
SECTION 10: STABILITY AND REACTIVITY
Hazardous Polymerization Will Not Occur __X__ May Occur____ Stability: Stable __X__ Unstable ____
Hazardous Decomposition/Combustion Products: NA
Conditions and Materials to Avoid: Strong oxidizing agents.
SECTION 11: TOXICOLOGICAL INFORMATION
Primary Route(s) of Exposure Under Normal Use: Inhalation, skin absorption, eye irritation, toxic if swallowed.
Target Organ(s): Diphenhydramine hydrochloride targets the central nervous system and is toxic by ingestion. Oxybutynin chloride targets
smooth muscle & bladder and is toxic by ingestion.
Acute Effects: Respiratory tract irritation; confusion, hallucinations
Diphenhydramine hydrochloride: Oral, rat: LD50= 500 mg/kg; Oxybutynin chloride: Oral, rat: LD50=460 mg/kg
Terfenadine: Oral, rat:LD50=5000 mg/kg; Teratogen: Oral, rat 1100 mg/kg; Reproductive Haz: Oral, rat 8400 mg/kg
Chronic Effects: Terfenadine:Teratogen: Oral, rat 1100 mg/kg; Reproductive Haz: Oral, rat 8400 mg/kg
Other Information: Chemical Ingredient(s) not classified as carcinogen(s) by OSHA, IARC, NTP, ACGIH, or California. Diphenhydramine
hydrochloride CAS# 147-24-0 and Oxybutynin chloride CAS# 1508-65-2 are listed as a RTK component in Pennsylvania and New Jersey.
SECTION 12: ECOLOGICAL INFORMATION
No information available on this preparation or mixture. By complying with sections 6 & 7 there will be no release into the environment.
SECTION 13: DISPOSAL CONSIDERATIONS
To determine proper disposal, consult applicable federal, state and local environmental control regulations.
SECTION 14: TRANSPORT INFORMATION
Shipment Name/Type: Non-hazardous for transport.
UN Number: NA Shipping/Hazardous Class: NA Packing Group: NA
Shipping regulations are based on combinations of criteria such as quantity, class and packaging according to DOT, IATA and (49) CFR.
SECTION 15: REGULATORY INFORMATION
EU Symbol of Danger: NA
EU Risk Phrases: NA
U.S. TSCA: Listed
Canada: This product contains the following components that are not on the Canadian DSL or NDSL list: Oxybutynin chloride
CAS# 1508-65-2. Coumarin 314 CAS# 55804-66-5 is listed on the Canadian NDSL list. This product has been classified
according to the hazard criteria of the CPR and this MSDS contains all the information required by the CPR.
SECTION 16: OTHER INFORMATION
United States EPA Regulatory Information: NFPA Rating: Health: 2 Flammability: 0 Reactivity: 0
SARA 313: NA
CERCLA RQ: NA HMIS Rating: Health: 2 Flammability: 0 Physical Hazard: 0
NOTE: NA = Data not available, not established, determined or not pertinent.
DISCLAIMER: The information contained herein has been compiled from data presented in various technical sources believed to be accurate. This information is
intended to be used only as a guide and does not purport to be complete. ERA makes no warranties and assumes no liability in connection with the use of this
information. It is the user's responsibility to determine the suitability of this information and to assure the adoption of necessary precautions.
MSDS Reference #: 716000261 PAGE 2 of 2
|