Material Data Safety Sheet
AutoGen, Inc.
84 October Hill Rd.
Holliston, MA 01746
(800) 292-5678
Date revised: 02-11-04
Emergency Telephone Number: (800) 424-9300
Agent: CHEMTREC
Section 1 ?Product and Company Information
Product Name: AGP245T Plasmid DNA - Resuspension Solution R-1
Product Number: PB-S1
Company: AutoGen, Inc.
Address: 84 October Hill Rd.
Holliston, MA 01746
Phone: (800) 292-5678
Fax: (508) 429-9765
Section 2 ?Composition/Information on Ingredients
Chemical name CAS #
Tris 77-86-1
EDTA 6381-92-6
RNase 9001-99-4
Section 3 - Hazards Identification
Emergency overview
Highly Toxic
Suspected Carcinogen
Target organs: Nerves, Liver, Heart, CNS, Kidneys, and Teeth
Section 4- First Aid Measures
Ingestion
Get medical attention immediately
Inhalation
Remove to fresh air. If breathing is impaired give oxygen. If breathing has
stopped, give artificial respiration and contact emergency medical personnel.
Skin Contact
Wash with copious amounts of water. Remove contaminated clothing and
contact a physician.
Eye contact
Flush with water for 15 minutes and contact a physician.
Wash contaminated clothing before reuse.
Section 5- Fire Fighting Measures
Extinguishing Media
Carbon dioxide, Dry Chemical Powder, or appropriate foam
Firefighting
Protective Equipment
Wear self-contained breathing apparatus and protective clothing to prevent
contact with skin and eyes
Special Procedures
Use water spray to cool fire-exposed containers
Specific Hazards
Vapor may travel a considerable distance to source of ignition and flashback
Section 6 ?Accidental Release Measures
Procedures in case of accidental leak or spill
Evacuate area
Shut off all sources of ignition
Personal Precaution Equipment
Wear self-contained breathing apparatus, rubber boots, and heavy rubber
gloves
Clean-up procedures
Cover with dry-lime, sand or soda ash. Place in covered containers, using non-
sparking tools. Transport outdoors. Ventilate area and wash spill site after
material pick-up is complete.
Section 7 ?Handling and Storage
Handling
Wear appropriate safety equipment. Especially chemical resistant gloves, safety
goggles, and other protective clothing. In very special cases, NIOSH/MSHA-
approved respirator may be required. Avoid contact with eyes, skin and
clothing. Avoid prolonged or repeated exposure. Do not breathe vapor.
Storage
Place at 4癈 for storage under 1 month. Place at -20癈 for long-term storage.
Keep tightly closed. Keep away from heat, sparks, and open flame.
Section 8 ?Exposure controls/Personal Protection
Personal Protective Equipment
Respiratory
NIOSH-approved respirator
Hand
Compatible chemical-resistant gloves
Eye
Chemical safety goggles
General hygiene measures
Wash hands thoroughly after handling
Section 9 ?Physical and Chemical Properties
Appearance
Physical State: liquid
Color: dilute yellow
Form: N/A
Characteristics
Molecular weight:
BP/BP range:
MP/MP range:
Freezing point:
Vapor Pressure:
Vapor Density:
Saturated vapor conc.:
SG/Density:
Bulk density:
Odor Threshold:
Volatile%:
V O C Content:
Water Content:
Solvent Content:
Evaporation Rate:
Viscosity:
Partition Coefficient:
Decomposition Temp.:
Flash Point F:
Flash Point C:
Explosion limits:
Flammability:
Autoignition Temp:
Section 10 ?Stability and Reactivity
Stability
Stable
Incompatible agents
Oxidizing agents, peroxides, acids, acid chlorides, acid anhydrides, alkali
metals, ammonia
Hazardous decomposition products
Carbon monoxide, carbon dioxide.
Hazardous polymerization
Will not occur.
Section 11 ?Toxicological Information
RETCS
Component Number
Tris TY2900000
EDTA AH4375000
Routes of exposure
May be harmful by inhalation, ingestion, or skin absorption
Possible effects
Irritation of the skin, eyes, mucous membranes, and upper respiratory tract.
CNS depression. Nausea, headache and vomiting. Narcotic effects. Damage
to the heart.
Target organs
Nerves, Liver, Heart, Kidneys, CNS, and Teeth.
Section 12 ?Ecological Information
Data not available.
Section 13 ?Disposal Considerations
General Instructions
Burn in a chemical incinerator equipped with an afterburner and scrubber but
exert extra care in igniting, as this material is highly flammable.
Observe all Federal, State, and Local environmental regulations.
Section 14 ?Transport Information
UN number:
Proper shipping name:
Hazard Class:
Hazard subclass:
Packing group:
Section 15 ?Regulatory Information
EU Directives Classification
Risk Statements
R: 36/37/38
Irritant. Irritating to eyes, respiratory system, and skin.
Safety Statements
S: 36/37/39
Wear suitable protective clothing, gloves, and eye/face protection.
Section 16 ?Other Information
Disclaimer
For R&D use only. Not for drug, household, or other uses.
Warranty
The factual information contained in this material safety data sheet is believed
to be accurate and reflects, to the best of our knowledge, the currently
available data pertaining to the chemicals. This information may be incomplete
and is used only as a guide. Users are encouraged to investigate the suitability
of the information with respect to their application. AutoGen, Inc. assumes no
responsibility resulting from the use or handling of this compound.
Material Data Safety Sheet
AutoGen, Inc.
84 October Hill Rd.
Holliston, MA 01746
(800) 292-5678
Date revised: 02-11-04
Emergency Telephone Number: (800) 424-9300
Agent: CHEMTREC
Section 1 ?Product and Company Information
Product Name: AGP245T Plasmid DNA - Lysis Solution
Product Number: PB-S2
Company: AutoGen, Inc.
Address: 84 October Hill Rd.
Holliston, MA 01746
Phone: (800) 292-5678
Fax: (508) 429-9765
Section 2 ?Composition/Information on Ingredients
Chemical name CAS #
Sodium Hydroxide 1310-73-2
N-lauroylsarcosine, sodium salt 137-16-6
Section 3 - Hazards Identification
Emergency overview
Highly Toxic
Suspected Carcinogen
Target organs: Nerves, Liver, Heart, CNS, Kidneys, and Teeth
Section 4- First Aid Measures
Ingestion
Get medical attention immediately
Inhalation
Remove to fresh air. If breathing is impaired give oxygen. If breathing has
stopped, give artificial respiration and contact emergency medical personnel.
Skin Contact
Wash with copious amounts of water. Remove contaminated clothing and
contact a physician.
Eye contact
Flush with water for 15 minutes and contact a physician.
Wash contaminated clothing before reuse.
Section 5- Fire Fighting Measures
Extinguishing Media
Carbon dioxide, Dry Chemical Powder, or appropriate foam
Firefighting
Protective Equipment
Wear self-contained breathing apparatus and protective clothing to prevent
contact with skin and eyes
Special Procedures
Use water spray to cool fire-exposed containers
Specific Hazards
Vapor may travel a considerable distance to source of ignition and flashback
Section 6 ?Accidental Release Measures
Procedures in case of accidental leak or spill
Evacuate area
Shut off all sources of ignition
Personal Precaution Equipment
Wear self-contained breathing apparatus, rubber boots, and heavy rubber
gloves
Clean-up procedures
Cover with dry-lime, sand or soda ash. Place in covered containers, using non-
sparking tools. Transport outdoors. Ventilate area and wash spill site after
material pick-up is complete.
Section 7 ?Handling and Storage
Handling
Wear appropriate safety equipment. Especially chemical resistant gloves, safety
goggles, and other protective clothing. In very special cases, NIOSH/MSHA-
approved respirator may be required. Avoid contact with eyes, skin and
clothing. Avoid prolonged or repeated exposure. Do not breathe vapor.
Storage
Place at 4癈 for storage under 1 month. Place at -20癈 for long-term storage.
Keep tightly closed. Keep away from heat, sparks, and open flame.
Section 8 ?Exposure controls/Personal Protection
Personal Protective Equipment
Respiratory
NIOSH-approved respirator
Hand
Compatible chemical-resistant gloves
Eye
Chemical safety goggles
General hygiene measures
Wash hands thoroughly after handling
Section 9 ?Physical and Chemical Properties
Appearance
Physical State: liquid
Color: dilute yellow
Form: N/A
Characteristics
Molecular weight:
BP/BP range:
MP/MP range:
Freezing point:
Vapor Pressure:
Vapor Density:
Saturated vapor conc.:
SG/Density:
Bulk density:
Odor Threshold:
Volatile%:
V O C Content:
Water Content:
Solvent Content:
Evaporation Rate:
Viscosity:
Partition Coefficient:
Decomposition Temp.:
Flash Point F:
Flash Point C:
Explosion limits:
Flammability:
Autoignition Temp:
Section 10 ?Stability and Reactivity
Stability
Stable
Incompatible agents
Oxidizing agents, peroxides, acids, acid chlorides, acid anhydrides, alkali
metals, ammonia
Hazardous decomposition products
Carbon monoxide, carbon dioxide.
Hazardous polymerization
Will not occur.
Section 11 ?Toxicological Information
RETCS
Component Number
Sodium hydroxide
N-lauroylsarcosine, sodium salt
Routes of exposure
May be harmful by inhalation, ingestion, or skin absorption
Possible effects
Irritation of the skin, eyes, mucous membranes, and upper respiratory tract.
CNS depression. Nausea, headache and vomiting. Narcotic effects. Damage
to the heart.
Target organs
Nerves, Liver, Heart, Kidneys, CNS, and Teeth.
Section 12 ?Ecological Information
Data not available.
Section 13 ?Disposal Considerations
General Instructions
Burn in a chemical incinerator equipped with an afterburner and scrubber but
exert extra care in igniting, as this material is highly flammable.
Observe all Federal, State, and Local environmental regulations.
Section 14 ?Transport Information
UN number: UN1824
Proper shipping name:
Hazard Class: 8
Hazard subclass:
Packing group: III
Section 15 ?Regulatory Information
EU Directives Classification
Risk Statements
R: 36/37/38
Flammable. Very toxic by Inhalation, contact with skin and ingestion. Causes
Burns. May cause cancer.
Safety Statements
S: 26 36
Wear suitable protective clothing, gloves, and eye/face protection. Keep away
from heat.
Section 16 ?Other Information
Disclaimer
For R&D use only. Not for drug, household, or other uses.
Warranty
The factual information contained in this material safety data sheet is believed
to be accurate and reflects, to the best of our knowledge, the currently
available data pertaining to the chemicals. This information may be incomplete
and is used only as a guide. Users are encouraged to investigate the suitability
of the information with respect to their application. AutoGen, Inc. assumes no
responsibility resulting from the use or handling of this compound.
Material Data Safety Sheet
AutoGen, Inc.
84 October Hill Rd.
Holliston, MA 01746
(800) 292-5678
Date revised: 02-11-04
Emergency Telephone Number: (800) 424-9300
Agent: CHEMTREC
Section 1 ?Product and Company Information
Product Name: AGP245T Plasmid DNA - Deproteinizing Solution A
Product Number: PB-S3
Company: AutoGen, Inc.
Address: 84 October Hill Rd.
Holliston, MA 01746
Phone: (800) 292-5678
Fax: (508) 429-9765
Section 2 ?Composition/Information on Ingredients
Chemical name CAS #
Potassium acetate 127-08-2
Chloroform 67-66-3
Phenol 108-95-2
Ethanol 64-17-5
Section 3 - Hazards Identification
Emergency overview
Highly Toxic
Suspected Carcinogen
Target organs: Nerves, Liver, Heart, CNS, Kidneys, and Teeth
Section 4- First Aid Measures
Ingestion
Get medical attention immediately
Inhalation
Remove to fresh air. If breathing is impaired give oxygen. If breathing has
stopped, give artificial respiration and contact emergency medical personnel.
Skin Contact
Wash with copious amounts of water. Remove contaminated clothing and
contact a physician.
Eye contact
Flush with water for 15 minutes and contact a physician.
Wash contaminated clothing before reuse.
Section 5- Fire Fighting Measures
Extinguishing Media
Carbon dioxide, Dry Chemical Powder, or appropriate foam
Firefighting
Protective Equipment
Wear self-contained breathing apparatus and protective clothing to prevent
contact with skin and eyes
Special Procedures
Use water spray to cool fire-exposed containers
Specific Hazards
Vapor may travel a considerable distance to source of ignition and flashback
Section 6 ?Accidental Release Measures
Procedures in case of accidental leak or spill
Evacuate area
Shut off all sources of ignition
Personal Precaution Equipment
Wear self-contained breathing apparatus, rubber boots, and heavy rubber
gloves
Clean-up procedures
Cover with dry-lime, sand or soda ash. Place in covered containers, using non-
sparking tools. Transport outdoors. Ventilate area and wash spill site after
material pick-up is complete.
Section 7 ?Handling and Storage
Handling
Wear appropriate safety equipment. Especially chemical resistant gloves, safety
goggles, and other protective clothing. In very special cases, NIOSH/MSHA-
approved respirator may be required. Avoid contact with eyes, skin and
clothing. Avoid prolonged or repeated exposure. Do not breathe vapor.
Storage
Place at 4癈 for storage under 1 month. Place at -20癈 for long-term storage.
Keep tightly closed. Keep away from heat, sparks, and open flame.
Section 8 ?Exposure controls/Personal Protection
Personal Protective Equipment
Respiratory
NIOSH-approved respirator
Hand
Compatible chemical-resistant gloves
Eye
Chemical safety goggles
General hygiene measures
Wash hands thoroughly after handling
Section 9 ?Physical and Chemical Properties
Appearance
Physical State: liquid
Color: dilute yellow
Form: N/A
Characteristics
Molecular weight:
BP/BP range:
MP/MP range:
Freezing point:
Vapor Pressure:
Vapor Density:
Saturated vapor conc.:
SG/Density:
Bulk density:
Odor Threshold:
Volatile%:
V O C Content:
Water Content:
Solvent Content:
Evaporation Rate:
Viscosity:
Partition Coefficient:
Decomposition Temp.:
Flash Point F:
Flash Point C:
Explosion limits:
Flammability:
Autoignition Temp:
Section 10 ?Stability and Reactivity
Stability
Stable
Incompatible agents
Oxidizing agents, peroxides, acids, acid chlorides, acid anhydrides, alkali
metals, ammonia
Hazardous decomposition products
Carbon monoxide, carbon dioxide.
Hazardous polymerization
Will not occur.
Section 11 ?Toxicological Information
RETCS
Component Number
Phenol SJ3325000
Chloroform FS9100000
Isoamyl Alcohol EL5425000
Ethanol KQ6300000
Acetic Acid, glacial AF1225000
Routes of exposure
May be harmful by inhalation, ingestion, or skin absorption
Possible effects
Irritation of the skin, eyes, mucous membranes, and upper respiratory tract.
CNS depression. Nausea, headache and vomiting. Narcotic effects. Damage
to the heart.
Target organs
Nerves, Liver, Heart, Kidneys, CNS, and Teeth.
Section 12 ?Ecological Information
Data not available.
Section 13 ?Disposal Considerations
General Instructions
Burn in a chemical incinerator equipped with an afterburner and scrubber but
exert extra care in igniting, as this material is highly flammable.
Observe all Federal, State, and Local environmental regulations.
Section 14 ?Transport Information
UN number: 1992
Proper shipping name: Flammable liquid, toxic, n.o.s.
Hazard Class: 3
Hazard subclass: 6.1
Packing group: III
Section 15 ?Regulatory Information
EU Directives Classification
Risk Statements
R: 10 26/27/28 34 45
Flammable. Very toxic by Inhalation, contact with skin and ingestion. Causes
Burns. May cause cancer.
Safety Statements
S: 15 36/37/38
Wear suitable protective clothing, gloves, and eye/face protection. Keep away
from heat.
Section 16 ?Other Information
Disclaimer
For R&D use only. Not for drug, household, or other uses.
Warranty
The factual information contained in this material safety data sheet is believed
to be accurate and reflects, to the best of our knowledge, the currently
available data pertaining to the chemicals. This information may be incomplete
and is used only as a guide. Users are encouraged to investigate the suitability
of the information with respect to their application. AutoGen, Inc. assumes no
responsibility resulting from the use or handling of this compound.
Material Data Safety Sheet
AutoGen, Inc.
84 October Hill Rd.
Holliston, MA 01746
(800) 292-5678
Date revised: 02-19-04
Emergency Telephone Number: (800) 424-9300
Agent: CHEMTREC
Section 1 ?Product and Company Information
Product Name: AGP245T Plasmid DNA - DNA Precipitation Solution A
Product Number: PB-S4
Company: AutoGen, Inc.
Address: 84 October Hill Rd.
Holliston, MA 01746
Phone: (800) 292-5678
Fax: (508) 429-9765
Section 2 ?Composition/Information on Ingredients
Chemical name CAS #
Isopropanol 66-63-0
Section 3 - Hazards Identification
Emergency overview
Highly Toxic
Suspected Carcinogen
Target organs: Nerves, Liver, Heart, CNS, Kidneys, and Teeth
Section 4- First Aid Measures
Ingestion
Get medical attention immediately
Inhalation
Remove to fresh air. If breathing is impaired give oxygen. If breathing has
stopped, give artificial respiration and contact emergency medical personnel.
Skin Contact
Wash with copious amounts of water. Remove contaminated clothing and
contact a physician.
Eye contact
Flush with water for 15 minutes and contact a physician.
Wash contaminated clothing before reuse.
Section 5- Fire Fighting Measures
Extinguishing Media
Carbon dioxide, Dry Chemical Powder, or appropriate foam
Firefighting
Protective Equipment
Wear self-contained breathing apparatus and protective clothing to prevent
contact with skin and eyes
Special Procedures
Use water spray to cool fire-exposed containers
Specific Hazards
Vapor may travel a considerable distance to source of ignition and flashback
Section 6 ?Accidental Release Measures
Procedures in case of accidental leak or spill
Evacuate area
Shut off all sources of ignition
Personal Precaution Equipment
Wear self-contained breathing apparatus, rubber boots, and heavy rubber
gloves
Clean-up procedures
Cover with dry-lime, sand or soda ash. Place in covered containers, using non-
sparking tools. Transport outdoors. Ventilate area and wash spill site after
material pick-up is complete.
Section 7 ?Handling and Storage
Handling
Wear appropriate safety equipment. Especially chemical resistant gloves, safety
goggles, and other protective clothing. In very special cases, NIOSH/MSHA-
approved respirator may be required. Avoid contact with eyes, skin and
clothing. Avoid prolonged or repeated exposure. Do not breathe vapor.
Storage
Place at 4癈 for storage under 1 month. Place at -20癈 for long-term storage.
Keep tightly closed. Keep away from heat, sparks, and open flame.
Section 8 ?Exposure controls/Personal Protection
Personal Protective Equipment
Respiratory
NIOSH-approved respirator
Hand
Compatible chemical-resistant gloves
Eye
Chemical safety goggles
General hygiene measures
Wash hands thoroughly after handling
Section 9 ?Physical and Chemical Properties
Appearance
Physical State: liquid
Color: dilute yellow
Form: N/A
Characteristics
Molecular weight:
BP/BP range:
MP/MP range:
Freezing point:
Vapor Pressure:
Vapor Density:
Saturated vapor conc.:
SG/Density:
Bulk density:
Odor Threshold:
Volatile%:
V O C Content:
Water Content:
Solvent Content:
Evaporation Rate:
Viscosity:
Partition Coefficient:
Decomposition Temp.:
Flash Point F:
Flash Point C:
Explosion limits:
Flammability:
Autoignition Temp:
Section 10 ?Stability and Reactivity
Stability
Stable
Incompatible agents
Oxidizing agents, peroxides, acids, acid chlorides, acid anhydrides, alkali
metals, ammonia
Hazardous decomposition products
Carbon monoxide, carbon dioxide.
Hazardous polymerization
Will not occur.
Section 11 ?Toxicological Information
RETCS
Component Number
Isopropanol
Routes of exposure
May be harmful by inhalation, ingestion, or skin absorption
Possible effects
Irritation of the skin, eyes, mucous membranes, and upper respiratory tract.
CNS depression. Nausea, headache and vomiting. Narcotic effects. Damage
to the heart.
Target organs
Nerves, Liver, Heart, Kidneys, CNS, and Teeth.
Section 12 ?Ecological Information
Data not available.
Section 13 ?Disposal Considerations
General Instructions
Burn in a chemical incinerator equipped with an afterburner and scrubber but
exert extra care in igniting, as this material is highly flammable.
Observe all Federal, State, and Local environmental regulations.
Section 14 ?Transport Information
UN number: UN1993
Proper shipping name: flammable liquid, n.o.s
Hazard Class: 3
Hazard subclass: N/A
Packing group: II
Section 15 ?Regulatory Information
EU Directives Classification
Risk Statements
R: 11 36 57
Flammable. Very toxic by Inhalation, contact with skin and ingestion. Causes
Burns. May cause cancer.
Safety Statements
S: 7 16 24/25 26
Wear suitable protective clothing, gloves, and eye/face protection. Keep away
from heat.
Section 16 ?Other Information
Disclaimer
For R&D use only. Not for drug, household, or other uses.
Warranty
The factual information contained in this material safety data sheet is believed
to be accurate and reflects, to the best of our knowledge, the currently
available data pertaining to the chemicals. This information may be incomplete
and is used only as a guide. Users are encouraged to investigate the suitability
of the information with respect to their application. AutoGen, Inc. assumes no
responsibility resulting from the use or handling of this compound.
Material Data Safety Sheet
AutoGen, Inc.
84 October Hill Rd.
Holliston, MA 01746
(800) 292-5678
Date revised: 02-19-04
Emergency Telephone Number: (800) 424-9300
Agent: CHEMTREC
Section 1 ?Product and Company Information
Product Name: AGP245T Plasmid DNA- DNA Wash Solution A
Product Number: PB-S5
Company: AutoGen, Inc.
Address: 84 October Hill Rd.
Holliston, MA 01746
Phone: (800) 292-5678
Fax: (508) 429-9765
Section 2 ?Composition/Information on Ingredients
Chemical name CAS #
Ethanol 64-17-5
Section 3 - Hazards Identification
Emergency overview
Highly Toxic
Suspected Carcinogen
Target organs: Nerves, Liver, Heart, CNS, Kidneys, and Teeth
Section 4- First Aid Measures
Ingestion
Get medical attention immediately
Inhalation
Remove to fresh air. If breathing is impaired give oxygen. If breathing has
stopped, give artificial respiration and contact emergency medical personnel.
Skin Contact
Wash with copious amounts of water. Remove contaminated clothing and
contact a physician.
Eye contact
Flush with water for 15 minutes and contact a physician.
Wash contaminated clothing before reuse.
Section 5- Fire Fighting Measures
Extinguishing Media
Carbon dioxide, Dry Chemical Powder, or appropriate foam
Firefighting
Protective Equipment
Wear self-contained breathing apparatus and protective clothing to prevent
contact with skin and eyes
Special Procedures
Use water spray to cool fire-exposed containers
Specific Hazards
Vapor may travel a considerable distance to source of ignition and flashback
Section 6 ?Accidental Release Measures
Procedures in case of accidental leak or spill
Evacuate area
Shut off all sources of ignition
Personal Precaution Equipment
Wear self-contained breathing apparatus, rubber boots, and heavy rubber
gloves
Clean-up procedures
Cover with dry-lime, sand or soda ash. Place in covered containers, using non-
sparking tools. Transport outdoors. Ventilate area and wash spill site after
material pick-up is complete.
Section 7 ?Handling and Storage
Handling
Wear appropriate safety equipment. Especially chemical resistant gloves, safety
goggles, and other protective clothing. In very special cases, NIOSH/MSHA-
approved respirator may be required. Avoid contact with eyes, skin and
clothing. Avoid prolonged or repeated exposure. Do not breathe vapor.
Storage
Place at 4癈 for storage under 1 month. Place at -20癈 for long-term storage.
Keep tightly closed. Keep away from heat, sparks, and open flame.
Section 8 ?Exposure controls/Personal Protection
Personal Protective Equipment
Respiratory
NIOSH-approved respirator
Hand
Compatible chemical-resistant gloves
Eye
Chemical safety goggles
General hygiene measures
Wash hands thoroughly after handling
Section 9 ?Physical and Chemical Properties
Appearance
Physical State: liquid
Color: dilute yellow
Form: N/A
Characteristics
Molecular weight:
BP/BP range:
MP/MP range:
Freezing point:
Vapor Pressure:
Vapor Density:
Saturated vapor conc.:
SG/Density:
Bulk density:
Odor Threshold:
Volatile%:
V O C Content:
Water Content:
Solvent Content:
Evaporation Rate:
Viscosity:
Partition Coefficient:
Decomposition Temp.:
Flash Point F:
Flash Point C:
Explosion limits:
Flammability:
Autoignition Temp:
Section 10 ?Stability and Reactivity
Stability
Stable
Incompatible agents
Oxidizing agents, peroxides, acids, acid chlorides, acid anhydrides, alkali
metals, ammonia
Hazardous decomposition products
Carbon monoxide, carbon dioxide.
Hazardous polymerization
Will not occur.
Section 11 ?Toxicological Information
RETCS
Component Number
Ethanol KQ6300000
Routes of exposure
May be harmful by inhalation, ingestion, or skin absorption
Possible effects
Irritation of the skin, eyes, mucous membranes, and upper respiratory tract.
CNS depression. Nausea, headache and vomiting. Narcotic effects. Damage
to the heart.
Target organs
Nerves, Liver, Heart, Kidneys, CNS, and Teeth.
Section 12 ?Ecological Information
Data not available.
Section 13 ?Disposal Considerations
General Instructions
Burn in a chemical incinerator equipped with an afterburner and scrubber but
exert extra care in igniting, as this material is highly flammable.
Observe all Federal, State, and Local environmental regulations.
Section 14 ?Transport Information
UN number: UN1993
Proper shipping name: flammable liquid, n.o.s
Hazard Class: 3
Hazard subclass: N/A
Packing group: II
Section 15 ?Regulatory Information
EU Directives Classification
Risk Statements
R: 10 26/27/28 34 45
Flammable. Very toxic by Inhalation, contact with skin and ingestion. Causes
Burns. May cause cancer.
Safety Statements
S: 15 36/37/38
Wear suitable protective clothing, gloves, and eye/face protection. Keep away
from heat.
Section 16 ?Other Information
Disclaimer
For R&D use only. Not for drug, household, or other uses.
Warranty
The factual information contained in this material safety data sheet is believed
to be accurate and reflects, to the best of our knowledge, the currently
available data pertaining to the chemicals. This information may be incomplete
and is used only as a guide. Users are encouraged to investigate the suitability
of the information with respect to their application. AutoGen, Inc. assumes no
responsibility resulting from the use or handling of this compound.
Material Data Safety Sheet
AutoGen, Inc.
84 October Hill Rd.
Holliston, MA 01746
(800) 292-5678
Date revised: 02-11-04
Emergency Telephone Number: (800) 424-9300
Agent: CHEMTREC
Section 1 ?Product and Company Information
Product Name: AGP245T Plasmid DNA - Resuspension Solution A
Product Number: PB-S6
Company: AutoGen, Inc.
Address: 84 October Hill Rd.
Holliston, MA 01746
Phone: (800) 292-5678
Fax: (508) 429-9765
Section 2 ?Composition/Information on Ingredients
Chemical name CAS #
Tris-HCl 77-86-1
EDTA 6381-92-6
Section 3 - Hazards Identification
Emergency overview
Highly Toxic
Suspected Carcinogen
Target organs: Nerves, Liver, Heart, CNS, Kidneys, and Teeth
Section 4- First Aid Measures
Ingestion
Get medical attention immediately
Inhalation
Remove to fresh air. If breathing is impaired give oxygen. If breathing has
stopped, give artificial respiration and contact emergency medical personnel.
Skin Contact
Wash with copious amounts of water. Remove contaminated clothing and
contact a physician.
Eye contact
Flush with water for 15 minutes and contact a physician.
Wash contaminated clothing before reuse.
Section 5- Fire Fighting Measures
Extinguishing Media
Carbon dioxide, Dry Chemical Powder, or appropriate foam
Firefighting
Protective Equipment
Wear self-contained breathing apparatus and protective clothing to prevent
contact with skin and eyes
Special Procedures
Use water spray to cool fire-exposed containers
Specific Hazards
Vapor may travel a considerable distance to source of ignition and flashback
Section 6 ?Accidental Release Measures
Procedures in case of accidental leak or spill
Evacuate area
Shut off all sources of ignition
Personal Precaution Equipment
Wear self-contained breathing apparatus, rubber boots, and heavy rubber
gloves
Clean-up procedures
Cover with dry-lime, sand or soda ash. Place in covered containers, using non-
sparking tools. Transport outdoors. Ventilate area and wash spill site after
material pick-up is complete.
Section 7 ?Handling and Storage
Handling
Wear appropriate safety equipment. Especially chemical resistant gloves, safety
goggles, and other protective clothing. In very special cases, NIOSH/MSHA-
approved respirator may be required. Avoid contact with eyes, skin and
clothing. Avoid prolonged or repeated exposure. Do not breathe vapor.
Storage
Place at 4癈 for storage under 1 month. Place at -20癈 for long-term storage.
Keep tightly closed. Keep away from heat, sparks, and open flame.
Section 8 ?Exposure controls/Personal Protection
Personal Protective Equipment
Respiratory
NIOSH-approved respirator
Hand
Compatible chemical-resistant gloves
Eye
Chemical safety goggles
General hygiene measures
Wash hands thoroughly after handling
Section 9 ?Physical and Chemical Properties
Appearance
Physical State: liquid
Color: dilute yellow
Form: N/A
Characteristics
Molecular weight:
BP/BP range:
MP/MP range:
Freezing point:
Vapor Pressure:
Vapor Density:
Saturated vapor conc.:
SG/Density:
Bulk density:
Odor Threshold:
Volatile%:
V O C Content:
Water Content:
Solvent Content:
Evaporation Rate:
Viscosity:
Partition Coefficient:
Decomposition Temp.:
Flash Point F:
Flash Point C:
Explosion limits:
Flammability:
Autoignition Temp:
Section 10 ?Stability and Reactivity
Stability
Stable
Incompatible agents
Oxidizing agents, peroxides, acids, acid chlorides, acid anhydrides, alkali
metals, ammonia
Hazardous decomposition products
Carbon monoxide, carbon dioxide.
Hazardous polymerization
Will not occur.
Section 11 ?Toxicological Information
RETCS
Component Number
Tris TY2900000
EDTA AH4375000
Routes of exposure
May be harmful by inhalation, ingestion, or skin absorption
Possible effects
Irritation of the skin, eyes, mucous membranes, and upper respiratory tract.
CNS depression. Nausea, headache and vomiting. Narcotic effects. Damage
to the heart.
Target organs
Nerves, Liver, Heart, Kidneys, CNS, and Teeth.
Section 12 ?Ecological Information
Data not available.
Section 13 ?Disposal Considerations
General Instructions
Burn in a chemical incinerator equipped with an afterburner and scrubber but
exert extra care in igniting, as this material is highly flammable.
Observe all Federal, State, and Local environmental regulations.
Section 14 ?Transport Information
Not Regulated
Section 15 ?Regulatory Information
EU Directives Classification
Risk Statements
R: 36/37/38
Irritant. Irritating to eyes, respiratory system and skin.
Safety Statements
S: 36/37/39
Wear suitable protective clothing, gloves, and eye/face protection.
Section 16 ?Other Information
Disclaimer
For R&D use only. Not for drug, household, or other uses.
Warranty
The factual information contained in this material safety data sheet is believed
to be accurate and reflects, to the best of our knowledge, the currently
available data pertaining to the chemicals. This information may be incomplete
and is used only as a guide. Users are encouraged to investigate the suitability
of the information with respect to their application. AutoGen, Inc. assumes no
responsibility resulting from the use or handling of this compound.
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