Product: Ozone from Oxygen P-6220-A Date: June 2000
Praxair Material Safety Data Sheet
1. Chemical Product and Company Identification
Product Name: Ozone from Oxygen (MSDS No. Trade Name: Not applicable
P-6220-A)
Chemical Name: Mixture of ozone and oxygen Synonyms: Triatomic oxygen in oxygen
Formula: Mixture of O3 and O2 Chemical Family: Not applicable
1-800-645-4633* Company Name: Praxair-Traligaz Ozone Company
Telephone: Emergencies:
CHEMTREC: 1-800-424-9300* 11501 Goldcoast Drive
1-800-PRAXAIR Cincinnati, OH 45249-1643
Routine:
* Call emergency numbers 24 hours a day only for spills, leaks, fire, exposure, or accidents involving this
product. For routine information, contact your supplier, Praxair sales representative, or call
1-800-PRAXAIR (1-800-772-9247).
2. Composition/Information on Ingredients
This MSDS applies to ozone mixtures produced by passing oxygen through an electrical discharge
tube or through ultraviolet radiation. For custom mixtures of this product, request an MSDS for
each component. See section 16 for important information about mixtures.
CAS CONCEN-
INGREDIENT NUMBER TRATION OSHA PEL ACGIH TLV-TWA
Ozone 10028-15-6 16% max 0.1 ppm See section 3.
Oxygen 7782-44-7 84% min. None currently established None currently established
Nitrogen Oxides See section 3. Trace See section 3. See section 3.
3. Hazards Identification
EMERGENCY OVERVIEW
DANGER! Toxic, oxidizing gas.
Harmful or fatal if inhaled.
Vigorously accelerates combustion.
Irritates and may damage eyes, skin, and respiratory system.
May cause dizziness or drowsiness.
Symptoms may be delayed
Self-contained breathing apparatus and protective clothing must be worn by
rescue workers.
Odor: Unpleasant, sulfur-like
Copyright ?1998, 2000, Praxair Technology, Inc. Page 1 of 10
All rights reserved.
Revised
Product: Ozone from Oxygen P-6220-A Date: June 2000
THRESHOLD LIMIT VALUE: Ozone: 0.1 ppm TLV-TWA, light work; 0.08 ppm, medium work;
0.05 ppm, heavy work; heavy, moderate, or light workloads < 2 hr*, 0.20 ppm (ACGIH, 1999). Nitrogen
oxides as by-products: Nitric oxide (NO, CAS# 10102-43-9), 25 ppm TLV-TWA (PEL 25 ppm);
nitrogen dioxide (NO2, CAS# 10102-44-0), 3 ppm TLV-TWA (PEL, 5 ppm ceiling); nitrous oxide (N2O,
CAS# 10024-97-2), 50 ppm TLV-TWA (PEL N/A); nitrogen pentoxide (N2O5, CAS# unk.), N/A. Acids:
nitrous acid (HNO2, CAS# 7782-77-6), N/A; nitric acid (HNO3, CAS# 7697-37-2), 2 ppm TLV-TWA
(PEL 2 ppm). TLV-TWAs should be used as a guide in the control of health hazards and not as fine lines
between safe and dangerous concentrations.
*The symbol < means "less than or equal to."
EFFECTS OF A SINGLE (ACUTE) OVEREXPOSURE:
INHALATION璄xposure to ozone concentrations above the TLV of 0.1 ppm may irritate the nose
and throat, and cause dryness. Pain or congestion in the chest may be accompanied by wheezing and
coughing. At concentrations above 0.3 ppm for 30 minutes, particularly in exercising individuals,
these symptoms are more likely. Eye irritation, headache, nausea, and alterations in pulmonary
function (lung impairment and breathing difficulty) may also occur. At concentrations above 0.9
ppm, respiratory effects worsen and drowsiness may occur. Levels near 9 ppm may cause
pneumonia, excessive sweating, decreased blood pressure, and weak and rapid pulse. Death may
occur from prolonged exposure at 2 ppm or short exposures (1-4 hours) at 10 ppm. Breathing 80% or
more oxygen at atmospheric pressure for more than a few hours may cause nasal stuffiness, cough,
sore throat, chest pain, and breathing difficulty. Breathing oxygen at higher pressure increases the
likelihood of adverse effects within a shorter time period. Breathing pure oxygen under pressure may
cause lung damage and also Central Nervous System (CNS) effects resulting in dizziness, poor
coordination, tingling sensation, visual and hearing disturbances, muscular twitching,
unconsciousness, and convulsions. Breathing oxygen under pressure may cause prolongation of
adaptation to darkness and reduced peripheral vision.
SKIN CONTACT瑿ontact with ozone may irritate the skin. Nitrogen oxide by-products may
combine with moisture in the skin and mucous membranes to form nitrogen acids, producing
chemical burns.
SWALLOWING瑼 highly unlikely route of exposure. This product is a gas at normal temperature
and pressure.
EYE CONTACT璄xposed persons may sense eye irritation at or above the TLV of 0.1 ppm ozone.
Exposure to ozone at 2 ppm over 4 hours has caused eye irritation in rabbits. Nitrous oxide is
moderately irritating to the eyes and nose at 50 ppm; 25 ppm is irritating to some people. Nitrogen
oxide by-products may combine with moisture in the eyes to form nitrogen acids, producing chemical
burns.
EFFECTS OF REPEATED (CHRONIC) OVEREXPOSURE: Prolonged, low level (0.3 ppm)
exposure to ozone may produce scarring and thickening of small air passages, resulting in chronic lung
disease. People with existing lung disease may show earlier and more severe symptoms when exposed to
ozone. An increased susceptibility to lung disease and infection may also occur.
OTHER EFFECTS OF OVEREXPOSURE: None known for ozone, but see section 16 for effects of
nitrogen compounds produced by the breakdown of ozone.
MEDICAL CONDITIONS AGGRAVATED BY OVEREXPOSURE: People with existing lung
disease may show earlier and more severe symptoms when exposed to ozone. An increased susceptibility
to lung disease and infection may also occur.
Page 2 of 10
Product: Ozone from Oxygen P-6220-A Date: June 2000
SIGNIFICANT LABORATORY DATA WITH POSSIBLE RELEVANCE TO HUMAN HEALTH
HAZARD EVALUATION: There is limited evidence that ozone in concentrations of over 1.5 ppm
may be lethal to rodent embryos. Studies of mutagenic effects in humans have been equivocal.
CARCINOGENICITY: Ozone is not listed by NTP, OSHA, and IARC.
4. First Aid Measures
INHALATION: Immediately remove to fresh air. If not breathing, give artificial respiration. Rescuer
should avoid inhaling air from victim. Get immediate medical attention.
SKIN CONTACT: Immediately flush skin with plenty of water while removing contaminated clothing
and shoes. Get immediate medical attention.
SWALLOWING: An unlikely route of exposure. This product is a gas at normal temperature and
pressure.
EYE CONTACT: Immediately flush eyes with plenty of cool water for at least 15 minutes. Hold the
eyelids open and away from the eyeballs to ensure that all surfaces are flushed thoroughly. Do not allow
victim to rub eyes. Get immediate medical attention.
NOTES TO PHYSICIAN: Keep victim under observation. Onset of breathing difficulties may be
delayed for up to 6 hours. There is no specific antidote. Treatment of overexposure should be directed at
the control of symptoms and the clinical condition of the patient. Supportive treatment for overexposure
to oxygen should include immediate sedation, anti-convulsive therapy if needed, and rest. See section 11,
Toxicological Information.
5. Fire Fighting Measures
Not applicable
FLASH POINT (test method):
Not applicable
AUTOIGNITION TEMPERATURE:
FLAMMABLE LIMITS IN AIR, % by volume: LOWER: Not applicable UPPER: Not applicable
EXTINGUISHING MEDIA: Ozone from oxygen cannot catch fire. Use media appropriate for
surrounding fire.
SPECIAL FIRE FIGHTING PROCEDURES: DANGER! Toxic, oxidizing gas. (See section 3.)
Evacuate all personnel from danger area. Do not approach area without self-contained breathing
apparatus and protective clothing. Immediately cool any cylinders with water spray from maximum
distance. Remove ignition sources if without risk. Stop flow of gas if without risk, while continuing
cooling water spray. Remove any gas cylinders from area of fire if without risk. Heat of fire can build
pressure in gas cylinders and cause rupture. No part of any cylinder should be subjected to a temperature
higher than 125癋 (52癈). On-site fire brigades must comply with OSHA 29 CFR 1910.156.
UNUSUAL FIRE AND EXPLOSION HAZARDS: Oxidizing agent; vigorously accelerates
combustion. Contact with flammables may cause fire or explosion. (See section 10.)
HAZARDOUS COMBUSTION PRODUCTS: Thermal decomposition of the nitric oxide by-product
may produce highly toxic nitrogen oxides. (See section 10.)
Page 3 of 10
Product: Ozone from Oxygen P-6220-A Date: June 2000
6. Accidental Release Measures
STEPS TO BE TAKEN IF MATERIAL IS RELEASED OR SPILLED: DANGER! Toxic,
oxidizing gas. (See section 3.) Immediately evacuate all personnel from danger area. Use self-contained
breathing apparatus where needed. Toxic gas may spread. Remove all sources of ignition if without risk.
Reduce gas with fog or fine water spray. Shut off flow if without risk. Ventilate area.
WASTE DISPOSAL METHOD: Prevent waste from contaminating the surrounding environment.
Keep personnel away. Discard any product, residue, disposable container, or liner in an environmentally
acceptable manner, in full compliance with federal, state, and local regulations. If necessary, call your
local supplier for assistance.
7. Handling and Storage
PRECAUTIONS TO BE TAKEN IN STORAGE: This mixture is produced and used in a closed
system and is not stored.
PRECAUTIONS TO BE TAKEN IN HANDLING: This mixture is produced and used in a closed
system and should not be handled.
8. Exposure Controls/Personal Protection
VENTILATION/ENGINEERING CONTROLS:
LOCAL EXHAUST瑼 corrosion-resistant system is acceptable so long as it maintains sufficient air
flow to keep the ozone concentration below the TLV in the worker's breathing zone. (See SPECIAL.)
MECHANICAL (general)璉nadequate; see SPECIAL.
SPECIAL璘se only in a closed system. Corrosion-resistant, forced-draft fume hood is preferred.
OTHER璖ee SPECIAL.
RESPIRATORY PROTECTION: Select per OSHA 29 CFR 1910.134 and ANSI Z88.2. Use any
NIOSH/MHSA-approved air-supplied respirator for concentrations up to 10 times the applicable
permissible exposure limit. For concentrations from 10 to 100 times the PEL, use the above respirator
fitted with a full facepiece, or use a self-contained breathing apparatus. For higher concentrations, a full-
face, self-contained breathing apparatus operated in the pressure demand mode is required.
PROTECTIVE GLOVES: Wear plastic (not rubber) gloves wherever contact with product is possible.
EYE PROTECTION: Wear vapor-proof goggles and a face shield wherever contact with product is
possible. Select per OSHA 29 CFR 1910.133.
OTHER PROTECTIVE EQUIPMENT: Protective clothing--plastic (not rubber)--and shoes
whenever contact with product is possible--at a minimum, whenever the generator or process system is
opened for any reason including routine inspection and maintenance. Select per OSHA 29 CFR 1910.132
and 1910.133. Regardless of protective equipment, never touch live electrical parts.
Page 4 of 10
Product: Ozone from Oxygen P-6220-A Date: June 2000
9. Physical and Chemical Properties
48 (ozone component)
MOLECULAR WEIGHT:
1.66 (ozone component)
SPECIFIC GRAVITY (Air = 1) at 32癋 (0癈) and 1 atm:
0.494
SOLUBILITY IN WATER, wt/wt at 32癋 (0癈) and 1 atm:
-168.34癋 (-111.3癈) (ozone
BOILING POINT at 1 atm:
component)
-313癋 (-191.7癈 ) (ozone component)
MELTING POINT at 1 atm:
APPEARANCE, ODOR, AND STATE: Colorless gas mixture at normal temperature and pressure;
unpleasant, sulfur-like odor.
10. Stability and Reactivity
STABILITY: Unstable Stable
INCOMPATIBILITY (materials to avoid): Oxidizable materials, both organic and inorganic;
hydrogen; iron, copper, chromium; water
HAZARDOUS DECOMPOSITION PRODUCTS: Nitric oxide, nitrogen dioxide, nitrogen pentoxide,
nitrous oxide, nitrous acid, nitric acid
HAZARDOUS POLYMERIZATION: May Occur Will Not Occur
CONDITIONS TO AVOID: Avoid contact with all oxidizable materials, both organic and inorganic,
including rubber. Ozone reacts with nonsaturated organic compounds to produce ozonides, which are
unstable and may decompose with explosive violence. Ozone is an unstable gas that at normal
temperatures decomposes to biatomic oxygen. At elevated temperatures and in the presence of certain
catalysts such as hydrogen, iron, copper, and chromium, this decomposition may be explosive.
11. Toxicological Information
Ozone: Human inhalation: TCLo: 1860 ppb/75 min caused watering eyes, decreased pulse rate, falling
blood pressure, and cough; 1 ppm caused cough, breathing difficulty, and other changes. Rat inhalation:
TCLo: 1500 ppb/24 hr (17 to 20 days pregnancy) caused behavioral disorders in newborn; 1040 ppt/24
hr (6 to 9 days pregnancy) caused developmental abnormalities of the musculoskeletal system. LC50:
4800 ppb/4-hrs (rat), LC50: 12600 ppb/3-hrs (mouse), LC50: 36ppm/3-hrs (rabbit). Oxygen: TCLo:
100 pph/14 hrs (human).
At atmospheric concentration and pressure, oxygen poses no toxicity hazards. At high concentrations,
newborn premature infants may suffer delayed retinal damage (retrolental fibroplasia) that can progress
to retinal detachment and blindness. Retinal damage may also occur in adults exposed to 100% oxygen
for extended periods (24 to 48 hours) or at greater than atmospheric pressure, particularly in individuals
whose retinal circulation has been previously compromised. All individuals exposed for long periods to
oxygen at high pressure and all who exhibit overt oxygen toxicity should have ophthalmologic
examinations.
At two or more atmospheres, toxicity to the CNS occurs. Symptoms include nausea, vomiting, dizziness
or vertigo, muscle twitching, vision changes, and loss of consciousness and generalized seizures. At three
atmospheres, CNS toxicity occurs in less than two hours; at six atmospheres, in only a few minutes.
Page 5 of 10
Product: Ozone from Oxygen P-6220-A Date: June 2000
Patients with chronic obstructive pulmonary disease retain carbon dioxide abnormally. If oxygen is
administered, raising their blood oxygen concentration, their breathing becomes depressed, and retained
carbon dioxide rises to a dangerous level.
Animal studies suggest that the administration of certain drugs, including phenothiazine drugs and
chloroquine, increases the susceptibility to toxicity from oxygen at high concentrations or pressures.
Animal studies also indicate that vitamin E deficiency may increase susceptibility to oxygen toxicity.
Airway obstruction during high oxygen tension may cause alveolar collapse following absorption of the
oxygen. Similarly, occlusion of the eustachian tubes may cause retraction of the eardrum and obstruction
of the paranasal sinuses may produce vacuum-type headache.
12. Ecological Information
No information is available on ecological effects. Ozone from oxygen does not contain any Class I or
Class II ozone-depleting chemicals. Ozone from oxygen is not listed as a marine pollutant by DOT.
13. Disposal Considerations
WASTE DISPOSAL METHOD: See section 6.
14. Transport Information
DOT/IMO SHIPPING NAME: Not shipped
HAZARD IDENTIFICATION PRODUCT
Not applicable Not applicable RQ: Not applicable
CLASS: NUMBER:
Not applicable
SHIPPING LABEL(s):
Not applicable
PLACARD (when required):
SPECIAL SHIPPING
Not applicable
INFORMATION:
15. Regulatory Information
The following selected regulatory requirements may apply to this product. Not all such requirements are
identified. Users of this product are solely responsible for compliance with all applicable federal, state,
and local regulations.
U.S. FEDERAL REGULATIONS:
EPA (ENVIRONMENTAL PROTECTION AGENCY)
CERCLA: COMPREHENSIVE ENVIRONMENTAL RESPONSE, COMPENSATION, AND
LIABILITY ACT OF 1980 (40 CFR Parts 117 and 302):
Reportable Quantity (RQ): None
Page 6 of 10
Product: Ozone from Oxygen P-6220-A Date: June 2000
SARA: SUPERFUND AMENDMENT AND REAUTHORIZATION ACT:
SECTIONS 302/304: Require emergency planning based on Threshold Planning Quantity
(TPQ) and release reporting based on Reportable Quantities (RQ) of extremely hazardous
substances (40 CFR Part 355):
Threshold Planning Quantity (TPQ): 100 lb (45.4 kg)
Extremely Hazardous Substances (40 CFR 355): 100 lb (45.4 kg)
SECTIONS 311/312: Require submission of MSDSs and reporting of chemical inventories
with identification of EPA hazard categories. The hazard categories for this product are as
follows:
IMMEDIATE: Yes PRESSURE: Yes
DELAYED: Yes REACTIVITY: Yes
FIRE: Yes
SECTION 313: Requires submission of annual reports of release of toxic chemicals that
appear in 40 CFR Part 372.
The ozone component of this mixture requires reporting under Section 313.
40 CFR 68: RISK MANAGEMENT PROGRAM FOR CHEMICAL ACCIDENTAL RELEASE
PREVENTION: Requires development and implementation of risk management programs at
facilities that manufacture, use, store, or otherwise handle regulated substances in quantities that
exceed specified thresholds.
None of the components of this mixture is listed as a regulated substance.
TSCA: TOXIC SUBSTANCES CONTROL ACT: The components of this mixture are listed on
the TSCA inventory.
OSHA: OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION:
29 CFR 1910.119: PROCESS SAFETY MANAGEMENT OF HIGHLY HAZARDOUS
CHEMICALS: Requires facilities to develop a process safety management program based on
Threshold Quantities (TQ) of highly hazardous chemicals.
The ozone component of this mixture is listed in Appendix A as a highly hazardous chemical
in quantities of 100 lb (45.4 kg) or greater.
STATE REGULATIONS:
CALIFORNIA: Ozone is not listed by California under the SAFE DRINKING WATER AND
TOXIC ENFORCEMENT ACT OF 1986 (Proposition 65).
PENNSYLVANIA: This product is subject to the PENNSYLVANIA WORKER AND
COMMUNITY RIGHT-TO-KNOW ACT (35 P.S. Sections 7301-7320).
16. Other Information
Be sure to read and understand all labels and instructions supplied or associated with this product.
ADDITIONAL SAFETY AND HEALTH HAZARDS: The presence of nitrogen and oxygen in the
corona discharge leads to the formation of small amounts of nitrogen oxides, mainly nitrogen pentoxide
(N2O5) and nitrogen dioxide (NO2). N2O5 is a yellowish white solid that sublimes at 86癋 (30癈) into
NO2 and O2. NO2 is a reddish brown gas that liquefies at 68癋 (20癈), forming a reddish brown liquid. In
contact with moisture in the feed gas, N2O5 forms highly corrosive nitric acid (HNO3). Generally, the
Page 7 of 10
Product: Ozone from Oxygen P-6220-A Date: June 2000
nitric acid will settle on the wall of the ozone generator. Inspection and maintenance personnel must take
care not to not to get this acid on their skin or clothing.
An ACGIH review suggests that a 60-minute exposure of humans to 100 ppm nitrogen dioxide (NO2)
leads to pulmonary edema with possible subacute or chronic lesions in the lungs, and 25 ppm leads to
respiratory irritation and chest pain. Whenever there is exposure to unusual amounts of nitrogen dioxide,
the exposed persons should be under medical supervision for a period of 72 hours to detect the earliest
signs of pulmonary edema. The odor of NO2 is perceptible for some persons at 0.11 ppm, and for most at
0.22 ppm. Dark adaptation and the ability to perceive dim lights is impaired by as little as 0.074 ppm.
Exposure to 0.7 to 2 ppm for 10 minutes causes increased resistance to the flow of air in the respiratory
tract.
OTHER HAZARDOUS CONDITIONS OF HANDLING, STORAGE, AND USE: Toxic, oxidizing
gas. Harmful or fatal if inhaled. Do not breathe gas. Do not get vapors or liquid in eyes, on skin, or on
clothing. (See section 3.) Have safety showers and eyewash fountains immediately available. Use piping
and equipment adequately designed to withstand pressures to be encountered. Use only in a closed
system constructed of corrosion-resistant materials. Never work on a pressurized system. If there is a
leak, shut the system down. Blow down the system and purge it per instructions, in an environmentally
safe manner and in compliance with all federal, state, and local laws, then repair the leak. Do not eat,
drink, or smoke in areas where ozone is used. Wash hands and face thoroughly to clean them of any
residual before eating, drinking, smoking, using the toilet, or applying cosmetics.
NOTE: Prior to using any plastics, confirm their compatibility with ozone by-products.
MIXTURES: When you mix two or more gases or liquefied gases, you can create additional,
unexpected hazards. Obtain and evaluate the safety information for each component before you produce
the mixture. Consult an industrial hygienist or other trained person when you evaluate the end product.
Remember, gases and liquids have properties that can cause serious injury or death.
HAZARD RATING SYSTEMS:
NFPA RATINGS: HMIS RATINGS:
=3 =3
HEALTH HEALTH
=0 =0
FLAMMABILITY FLAMMABILITY
=1 =1
REACTIVITY REACTIVITY
= OX
SPECIAL
Ask your supplier about free Praxair safety literature. Further safety information can be found in the
following pamphlets published by the Compressed Gas Association, Inc. (CGA), 1725 Jefferson Davis
Highway, Arlington, VA 22202-4102, Telephone (703) 412-0900.
P-1 Safe Handling of Compressed Gases in Containers
P-14 Accident Prevention in Oxygen-Rich, Oxygen-Deficient Atmospheres
-- Handbook of Compressed Gases, Third Edition
Page 8 of 10
Product: Ozone from Oxygen P-6220-A Date: June 2000
Praxair asks users of this product to study this MSDS and become aware of product hazards and safety
information. To promote safe use of this product, a user should (1) notify employees, agents, and
contractors of the information in this MSDS and of any other known product hazards and safety
information, (2) furnish this information to each purchaser of the product, and (3) ask each purchaser to
notify its employees and customers of the product hazards and safety information.
Page 9 of 10
Product: Ozone from Oxygen P-6220-A Date: June 2000
The opinions expressed herein are those of qualified experts within Praxair, Inc. We
believe that the information contained herein is current as of the date of this Material
Safety Data Sheet. Since the use of this information and the conditions of use of the
product are not within the control of Praxair, Inc., it is the user's obligation to
determine the conditions of safe use of the product.
Praxair MSDSs are furnished on sale or delivery by Praxair or the independent distributors and suppliers
who package and sell our products. To obtain current Praxair MSDSs for these products, contact your
Praxair sales representative or local distributor or supplier. If you have questions regarding Praxair
MSDSs, would like the form number and date of the latest MSDS, or would like the names of the Praxair
suppliers in your area, phone or write the Praxair Call Center (Phone: 1-800-PRAXAIR; Address:
Praxair Call Center, Praxair, Inc., PO Box 44, Tonawanda, NY 14150-7891).
Praxair and the Flowing Airstream design are trademarks or registered trademarks of
Praxair Technology, Inc. in the United States and other countries.
Praxair, Inc.
39 Old Ridgebury Road
Danbury, CT 06810-5113
Page 10 of 10
Printed in USA
|