Epigentek Epigentek Group Inc
760 Parkside Avenue
Brooklyn, 11226
Brooklyn, NY 11226
Keep it Simple and Smart
Phone: 718-484-3990
Fax: 718-484-3956
www.epigentek.com
MSDS Information for:
Cat.
Cat. # 1010
Methylamp鈩? One- Modification
Methylamp鈩? One-Step DNA Modification Kit
Safet
afety
A Material Safety Data Sheet (MSDS) for the product as a whole is not required, as it is
a kit consisting of individual components.
The following components are defined as hazardous (See MSDS page)
G3 (Balance solution)
G1 (DNA modification)
non-
The following components are defined as non-hazardous and do not require MSDS.
above
The products do not contain any hazardous components above 1% or any
carcinogens above 0.1% as defined in 29 CFR 1910. 1200, the OSHA Hazard
Standard.
Communication Standard.
G2 (DNA modification)
G4 (modified DNA capture)
G5 (modified DNA clean)
G6 (modified DNA elution)
P-spin M column
P-collection tube
Material Safety Data Sheet
1.
Section 1. Identification
MethylampTM One-Step DNA Modification Kit
Product Name
P-1010-1
Product No.
Epigentek Group Inc.
Supplier
760 Parkside Ave.
Brooklyn, NY 11226
718-484-3990
In Case of Emergency
Section 2. Composition, Information on Ingredients
Ingredient Name
G3 Balance solution
1
Identification
Section 3. Hazards Identification
Emergency Overview
Causes severe irritation and burns. Harmful if swallowed. Avoid breathing vapor or dust. Use
with adequate ventilation. Avoid contact with eyes, skin, and clothes. Wash hands thoroughly
after handling. Keep container closed.
Potential Health Effects
Severe irritant. Effects from inhalation of mist vary from mild irritation to serious
Inhalation:
damage of the upper respiratory tract, depending on severity of exposure. Symptoms
may include sneezing, sore throat, or runny nose. Severe pneumonitis may occur.
Corrosive! Swallowing may cause severe burns of mouth, throat, and stomach. Severe
Ingestion:
scarring of tissue and death may result. Symptoms may include bleeding, vomiting,
diarrhea, and decrease of blood pressure. Damage may appear days after exposure.
Corrosive! Contact with skin can cause irritation or severe burns and scarring with
Skin Contact:
greater exposures.
Corrosive! Causes irritation of eyes, and with greater exposures it can cause burns that
Eye Contact:
may result in permanent impairment of vision, even blindness.
Chronic
Prolonged contact with dilute solutions or dust has a destructive effect upon tissue.
Exposure:
Section 4. First Aid Measures
Quickly move victim to fresh air. If not breathing, give artificial respiration. If breathing
Inhalation:
is difficult, give oxygen supply. Call a physician.
Ingestion: DO NOT INDUCE VOMITING! Give large quantities of water or milk if available.
Never give anything by mouth to an unconscious person. Get medical attention
immediately.
Skin Contact: Immediately flush skin with plenty of water for at least 15 minutes while removing
contaminated clothing and shoes. Call a physician, immediately. Wash clothing
before reuse.
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and
upper eyelids occasionally. Get medical attention immediately.
Note to Physician:
Perform endoscopy in all cases of suspected sodium hydroxide ingestion. In cases of severe
esophageal corrosion, the use of therapeutic doses of steroids should be considered. General
supportive measures with continual monitoring of gas exchange, acid-base balance,
electrolytes, and fluid intake are also required.
Section
Section 5. Fire Fighting Measures
Fire
Not considered to be a fire hazard. Hot or molten material can react violently with
Fire:
water. Can react with certain metals, such as aluminum, to generate flammable
hydrogen gas.
May cause fire and explosions when in contact with incompatible materials.
Explosion:
Extinguishing
Use any appropriate means suitable for extinguishing surrounding fire. Adding water
Media:
to caustic solution generates large amounts of heat.
2
Special
In the event of a fire, wear full protective clothing and NIOSH-approved self-
Information:
contained breathing apparatus.
Section 6. Accidental Release Measures
Ventilate area of leak or spill. Keep unnecessary and unprotected people away from area of
spill. Absorb spill with inert material, then place in a chemical waste container. Neutralize with
a weak acid.
Section 7. Handling and Storage
7.
Keep in a tightly closed container. Protect from physical damage. Store in a cool, dry,
ventilated area away from sources of heat, moisture, and incompatibilities. Wash hands
thoroughly after handling.
Section 8. Exposure Controls/Personal Protection
Section
Respiratory
NIOSH/MSHA-approved respirator
Protection:
Skin Protection: Wear impervious protective clothing, including boots, gloves, lab coat, apron or
coveralls, as appropriate, to prevent skin contact.
Eye Protection: Use chemical safety goggles. Maintain eye wash fountain and quick-drench facilities in
work area.
Section 9. Physical and Chemical Properties
Appearance:
Appearance: Clear, colorless solution.
Odorless.
Odor:
Completely miscible with water.
Solubility:
14.0
pH:
No information found.
% Volatiles
Information not available
Boiling Point:
Not applicable
Melting Point:
Density: No information found.
Vapor Density:
Information not available.
Vapor Pressure:
Evaporation
No information found.
Rate:
Section 10. Stability and Reactivity
Stable under ordinary conditions of use and storage.
Stability:
Not established.
Hazardous Decomposition:
olymerization: Will not occur.
Hazardous Polymerization:
Acids, flammable liquids, organic halogens, metals, nitrocompounds.
Materials to Avoid:
Heat, incompatibles.
Conditions to Avoid:
Section 11. Toxicological Information
Data
ata: Skin, rabbit: 500 mg/24H severe; eye rabbit: 50 ug/24H severe.
Irritation Data
3
Carcinogen:
Carcinogen: Not considered to be carcinogenic by ACGIH and IARC
12.
Section 12. Ecological Information
Environmental Fate: No information found.
Environmental Toxicity: No information found.
Section 13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and
approved waste facility. Although not a listed RCRA hazardous waste, this material may exhibit one or
more characteristics of a hazardous waste and require appropriate analysis to determine specific
disposal requirements. Processing, use, or contamination of this product may change the waste
management options. State and local disposal regulations may differ from federal disposal regulations.
Dispose of container and unused contents in accordance with federal, state and local requirements.
Section 14. Transport Information
Information not available.
Section 15. Regulatory Information
OSHA Hazard Communication Evaluation
Meets criteria for hazardous material, as defined by 29 CFR 1910.1200
Section 16. Other Information
The information above is believed to be accurate and represents the best information currently available
to us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their
own investigations to determine the suitability of the information for their particular purposes. In no way
shall the company be liable for any claims, losses, or damages of any third party or for lost profits or any
special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if the
company has been advised of the possibility of such damages.
Material Safety Data Sheet
Data Sheet
Section 1. Identification
Methylamp鈩? One-Step DNA Modification Kit
Product Name
P-1010
Product No.
Epigentek Group Inc.
Supplier
760 Parkside Ave.
Brooklyn, NY 11226
Ca Emergency 718-484-3990
In Case of Emergency
Section 2. Composition, Information on Ingredients
4
Ingredient Name
G1 DNA Modification Ingredient 1
Section 3. Hazards Identification
Emergency Overview
Harmful if swallowed. Contact with acids liberates toxic gas.
Irritating to eyes and respiratory system. Moisture sensitive. Air sensitive.
Potential Health Effects
Cause eye irritation.
Eye:
Skin:
Skin: May cause skin irritation.
Ingestion: Harmful if swallowed. May cause irritation of the digestive tract.
Ingestion:
Inhalation:
nhalation: Causes respiratory tract irritation.
nhalation
Chronic: Not available.
Chronic
Section 4. First Aid Measures
Measures
Eye:
Eye: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper
and lower lids. Seek medical attention.
Skin:
Skin: Flush skin with plenty of soap and water for at least 15 minutes while removing
contaminated clothing and shoes.
Ingestion:
Ingestion: Get medical aid. Rinse mouth out with water.
Inhalation:
nhalation: Quickly move victim from exposure to fresh air immediately. If not breathing, give
nhalation
artificial respiration. If breathing is difficult, give oxygen supply.
Fire Fighting Measures
Section 5. Fire Fighting Measures
General
Information:
nformation: As in any fire, wear a self-contained breathing apparatus in pressure-
demand, MSHA/NIOSH (approved or equivalent), and full protective
gear. Substance is noncombustible.
Extinguishing
edia: Substance is noncombustible; use agent most appropriate to extinguish surrounding
Media:
fire.
Autoignition
Not applicable.
Temperature:
Point: Not available
Flash Point:
Rating: Health 1; Flammability 0; instability 0.
NFPA Rating:
Explosion Limits Not available.
Release Measures
Section 6. Accident Release Measures
General
Information:
Information: Use proper personal protective equipment as indicated in Section 8.
Sweep up then place into a suitable container for disposal. Avoid generating dusty
Spills/Leaks
conditions.
5
andl
Section 7. Handling and Storage
Handling:
Handling: Wash hands thoroughly after handing. Use with adequate ventilation. Minimize dust
dling
generation and accumulation. Avoid contact with skin and eyes. Keep container
.
tightly closed. Avoid breathing dust.
Storage:
Storage: Store in a cool, dry place. Store in a tightly closed container.
Protection
Section 8. Exposure Control and Personal Protection
Engineering
Controls:
Controls: Use adequate general or local exhaust ventilation to keep airborne concentrations
below the permissible exposure limits.
Eye:
Eye: Wear safety glasses and chemical goggles if splashing is possible.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Skin:
Clothing: Wear appropriate protective clothing to minimize contact with skin.
Clothing:
Respirators: Following the OSHA respirator regulations found in 29CFR 1910.134 or
Respirators:
European Standard EN 149.
Section 9. Physical and Chemical Properties
tate: Solid
Physical State:
Appearance
Appearance: White
Odor: Sulfur dioxide odor
Odor:
pH: Acidic in solution
pH:
ressure: Not applicable
Vapor Pressure:
Viscosity: Not applicable
Viscosity:
Density
ensity: Not applicable
Vapor Density:
Point
oint: Not applicable
Boiling Point:
Point
oint: Not applicable
Freeze/Melting Point:
emperature: Not applicable
Decomposition Temperature:
Solubility: Soluble
Solubility:
ravity/Density: 1.48
Specific Gravity/Density:
10.
Section 10. Stability and reactivity
Stability: Stable. However, may decompose if heated. Oxidazes when exposure to air.
Chemical Stability:
Moisture sensitive.
Avoid: Incompatible materials, exposure to air, acids, exposure to moist air or water,
Conditions to Avoid:
temperatures above 125掳C.
Incompatibilities with
Materials: Strong oxidizing agents, acids, sodium nitrate.
Other Materials:
Hazardous
Decomposition Products: Oxides of sulfur
Products:
Hazardous
Has not been reported.
Polymerization:
11.
Section 11. Toxicological Information
CAS# 7681-57-4: UX8225000
RTECS#:
6
LD50/LC50:
LD50/LC50: CAS# 7681-57-4: Dermal, guinea pig: LD50 > 1 g/kg; Oral, rat: LD50 = 1130-
0/LC50
1900 mg/kg
Carcinogenicity: CAS# 7681-57-4. ACS - ACGIH: A4 - Not Classifiable as a Human Carcinogen
Carcinogenicity:
See actual entry in RTECS for complete information.
Section 12. Ecological Information
No information available.
13.
Section 13. Disposal Considerations
Dispose of in a manner consistent with federal, state, and local regulations.
14.
Section 14. Transport Information
No information available
15. Information
Section 15. Regulatory Information
FEDERAL: Listed on the TSCA inventory.
US FEDERAL:
International Regulations:
Regulations: European Labeling in Accordance with EC Directives
XN
Hazard Symbols:
16.
Section 16. Other Information
The information above is believed to be accurate and represents the best information currently available
to us. However, we make no warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use. Users should make their
own investigations to determine the suitability of the information for their particular purposes. In no way
shall the company be liable for any claims, losses, or damages of any third party or for lost profits or any
special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if the
company has been advised of the possibility of such damages.
7
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