MATERIAL SAFETY
DATA SHEET
Prepared to U.S. OSHA, CMA, ANSI and Canadian WHMIS Standards
1. PRODUCT IDENTIFICATION
CHEMICAL NAME; CLASS: NON-FLAMMABLE GAS MIXTURE
Containing < 1% Methyl Chloride, < 23.5% Oxygen in a Nitrogen Balance Gas
SYNONYMS: Not Applicable
CHEMICAL FAMILY NAME: Not Applicable
FORMULA: Not Applicable
Document Number: 50067
Note: The Material Safety Data Sheet is for this gas mixture supplied in cylinders with 33 cubic feet (935 liters) or less gas capacity (DOT - 39
cylinders). This MSDS has been developed for various gas mixtures with the composition of components within the ranges listed in Section 2
(Composition and Information on Ingredients). Refer to the product label for information on the actual composition of the product.
PRODUCT USE: Calibration of Monitoring and Research
Equipment
SUPPLIER/MANUFACTURER'S NAME: CALGAZ, LLC
ADDRESS: 821 Chesapeake Drive
Cambridge, MD 21613
EMERGENCY PHONE: CHEMTREC: 1-800-424-9300
BUSINESS PHONE: 1-410-228-6400
General MSDS Information: 1-713/868-0440
Fax on Demand: 1-800/231-1366
2. COMPOSITION and INFORMATION ON INGREDIENTS
CHEMICAL NAME CAS # mole % EXPOSURE LIMITS IN AIR
ACGIH-TLV OSHA-PEL NIOSH OTHER
TWA STEL TWA STEL IDLH
ppm ppm ppm ppm ppm ppm
Methyl Chloride 74-87-3 < 1% 50 100 100 200 (ceiling) 2000 NIOSH REL:
(skin) (skin) Reduce to lowest feasible
300 (5
50 (Vacated
concentration (LOQ 1.6)
minute
1989 PEL)
DFG MAKs:
peak in any
TWA = 50
3 hrs)
PEAK = 1鈥AK 15 min.
See 29 100
average value
(Vacated
DFG MAK Pregnancy Risk
1989 PEL)
Classification: B
Carcinogen: EPA-D, EPA-
CBD, IARC-3, MAK-3B,
NIOSH-Ca, TLV-A2
Oxygen 7782-44-7 < 23.5% There are no specific exposure limits for Oxygen. Oxygen levels should be maintained above
19.5%.
Nitrogen 7727-37-9 Balance There are no specific exposure limits for Nitrogen. Nitrogen is a simple asphyxiant (SA).
Oxygen levels should be maintained above 19.5%.
NE = Not Established. See Section 16 for Definitions of Terms Used.
NOTE (1): ALL WHMIS required information is included in appropriate sections based on the ANSI Z400.1-1998 format. This product has been
classified in accordance with the hazard criteria of the CPR and the MSDS contains all the information required by the CPR.
3. HAZARD IDENTIFICATION
EMERGENCY OVERVIEW: This is a colorless, gas mixture, which may have a very faint sweet, ethereal odor,
due to the presence of Methyl Chloride. The main health hazard presented by exposure to this gas mixture is the
danger of producing and oxygen deficient atmosphere if the gas is released (especially in small confined spaces
or other poorly-ventilated environments); individuals in such atmospheres may be asphyxiated. Although the
Methyl Chloride component causes depression of the central nervous system in pure form, this effect is not
normally seen in acute exposure in concentrations below 500 ppm. Chronic inhalation exposure may produce
adverse central nervous system effects at levels of 200 ppm or more. Prolonged inhalation exposure, skin or eye
contact in the presence of moisture may be irritating, due to formation of hydrochloric acid. The Methyl Chloride
component is a suspect carcinogen and reproductive toxin. All contact with this gas mixture should be prevented.
This gas mixture is not flammable or reactive. The Methyl Chloride component will slowly hydrolyze in the
presence of moisture to form corrosive hydrochloric acid. If involved in a fire this gas mixture may produce toxic
hydrogen chloride gas, phosgene and carbon monoxide. Cylinders exposed to high temperatures or direct flame
can rupture or burst.
SYMPTOMS OF OVEREXPOSURE BY ROUTE OF EXPOSURE: The most significant route of overexposure for
this product is by inhalation.
NON-FLAMMABLE GAS MIXTURE MSDS - 50067 EFFECTIVE DATE: APRIL 19, 2005
PAGE 1 OF6
3. HAZARD IDENTIFICATION(Continued)
INHALATION: Due to the small size of an individual cylinder of
this product, no unusual health effects from overexposure to the H A Z A R D O U S M A T E R IA L ID E N T IF IC A T IO N S Y S T E M
product are anticipated under routine circumstances of use.
Releases of this gas mixture may produce oxygen-deficient HEALTH HAZARD 1
(B L U E )
atmospheres (especially in small confined spaces or other poorly-
ventilated environments); individuals in such atmospheres may be
asphyxiated. The Methyl Chloride component of this product F L A M M A B IL IT Y H A Z A R D 0
(R E D )
begins to produce adverse effects on the central nervous system
at 500 ppm. Prolonged inhalation exposure may be irritating due
P H Y S IC A L H A Z A R D
to moisture in the respiratory system and the formation of (Y E L L O W ) 0
hydrochloric acid. Chronic inhalation exposure to the Methyl
Chloride component (exposures of at least two weeks) to levels of B
P R O T E C T IV E E Q U IP M E N T
200-400 ppm have produced central nervous system effects
(drowsiness, dizziness, misty vision, mental confusion, EYES HANDS BODY
R E S P IR A T O R Y
staggering, and slurred speech. S e e S e c tio n 8
SKIN AND EYES: This gas mixture may be irritating to the skin if
contact is prolonged and in the presence of moisture, as the F o r R o u tin e In d u s tr ia l U s e a n d H a n d lin g A p p lic a tio n s
Methyl Chloride component slowly hydrolyzes to form hydrochloric
acid. The gas mixture may be irritating to the eyes due to possible formation of hydrochloric acid. The Methyl
Chloride component of this gas mixture can be absorbed via intact skin. No adverse effects is expected to occur
from this gas mixture due to this route of exposure due to the low level of Methyl Chloride in the mixture. If a large
area of the skin is involved, some symptoms described under 鈥淚nhalation鈥? may occur.
HEALTH EFFECTS OR RISKS FROM EXPOSURE: An Explanation in Lay Terms. Overexposure to this gas
mixture may cause the following health effects:
ACUTE: Due to the small size of the individual cylinder of this product, no unusual health effects from exposure to
the product are anticipated under routine circumstances of use. In the presence of moisture, this gas mixture may
be irritating by inhalation, skin or eye contact due to formation of hydrochloric acid, especially if exposure is
prolonged.
CHRONIC: Chronic inhalation exposure may cause adverse effects on the central nervous system, due to the
presence of Methyl Chloride. Animal tests involving the Methyl Chloride component indicate damage to the liver and
kidneys may result after chronic inhalation exposure. The Methyl Chloride component of this product is a suspect
human carcinogen and reproductive toxin. See Section 11 (Toxicological Information) for further information.
TARGET ORGANS: ACUTE: Respiratory system, skin, eyes, central nervous system. CHRONIC: Reproductive
system, central nervous system, liver and kidneys.
4. FIRST-AID MEASURES
RESCUERS SHOULD NOT ATTEMPT TO RETRIEVE VICTIMS OF EXPOSURE TO THIS PRODUCT
WITHOUT ADEQUATE PERSONAL PROTECTIVE EQUIPMENT. At a minimum, Self-Contained Breathing
Apparatus must be worn. Victim(s) who experience any adverse effect after overexposure to this product must be
taken for medical attention. Rescuers should be taken for medical attention if necessary. Take a copy of the label
and the MSDS to physician or other health professional with victim(s). No unusual health effects are anticipated
after exposure to this product, due to the small cylinder size. (continued on following page)
If any adverse symptom develops after overexposure to this product, remove victim(s) to fresh air as quickly as
possible. Only trained personnel should administer supplemental oxygen and/or cardio-pulmonary resuscitation if
necessary.
MEDICAL CONDITIONS AGGRAVATED BY EXPOSURE: Pre-existing respiratory conditions and other disorders
may be aggravated by overexposure to this product.
RECOMMENDATIONS TO PHYSICIANS: Physicians should not administer adrenaline as a stimulant in case of
Methyl Chloride poising. Administer oxygen, if necessary; treat symptoms; reduce or eliminate exposure.
5. FIRE-FIGHTING MEASURES
FLASH POINT: Not applicable.
NFPA RATING
AUTOIGNITION TEMPERATURE: Not applicable.
FLAMMABLE LIMITS (in air by volume, %): FLAMMABILITY
Lower (LEL): Not applicable.
Upper (UEL): Not applicable. 0
FIRE EXTINGUISHING MATERIALS: Non-flammable gas mixture.
Use extinguishing media appropriate for surrounding fire. 0
1
HEALTH REACTIVITY
UNUSUAL FIRE AND EXPLOSION HAZARDS: This gas mixture is
not flammable; however, containers, when involved in fire, may
rupture or burst in the heat of the fire. If involved in a fire this gas
mixture may produce toxic hydrogen chloride gas, phosgene and
carbon monoxide. OTHER
Explosion Sensitivity to Mechanical Impact: Not Sensitive.
Explosion Sensitivity to Static Discharge: Not Sensitive.
SPECIAL FIRE-FIGHTING PROCEDURES: The Methyl Chloride component is considered to be is toxic and a
suspected human carcinogen and reproductive toxin. Do not enter fire area without wearing specialized
protective/equipment suitable for the situation. Firefighter's normal protective clothing (Bunker Gear) will not provide
adequate protection. A full-body encapsulating chemical resistant suit with positive pressure Self-Contained
Breathing Apparatus (NIOSH-approved or equivalent) may be necessary.
6. ACCIDENTAL RELEASE MEASURES
LEAK RESPONSE: Due to the small size and content of the cylinder, an accidental release of this product presents
significantly less risk of an oxygen-deficient environment and other safety hazards than a similar release from a
larger cylinder. However, as with any chemical release, extreme caution must be used during emergency response
procedures. In the event of a release in which the atmosphere is unknown, and in which other chemicals are
potentially involved, evacuate immediate area. Such releases should be responded to by trained personnel using
pre-planned procedures.Proper protective equipment should be used. In case of a leak, clear the affected area and
protect people. For emergency disposal, secure the cylinder and slowly discharge the gas to the atmosphere in a
well-ventilated area or outdoors. Allow the gas mixture to dissipate. If necessary, monitor the surrounding area (and
the original area of the release) for oxygen and the level of Methyl Chloride.
NON-FLAMMABLE GAS MIXTURE MSDS - 50067 EFFECTIVE DATE: APRIL 19, 2005
PAGE 2 OF6
6. ACCIDENTAL RELEASE MEASURES(Continued)
Oxygen levels must be above 19.5% and the level of Methyl Chloride must be below the TLV before non-emergency
personnel are allowed to re-enter area. If leaking incidentally from the cylinder or its valve, contact your supplier.
7. HANDLING and USE
WORK PRACTICES AND HYGIENE PRACTICES: Be aware of any signs of dizziness or fatigue; exposures to
fatal concentrations of this product could occur without any significant warning symptoms, due to oxygen deficiency.
Do not attempt to repair, adjust, or in any other way modify the cylinders of this product. If there is a malfunction or
another type of operational problem, contact nearest distributor immediately.
STORAGE AND HANDLING PRACTICES: Cylinders should be firmly secured to prevent falling or being knocked-
over. Cylinders must be protected from the environment, and preferably kept at room temperature (approximately
21掳C [70掳F]). Cylinders should be stored in dry, well-ventilated areas, away from sources of heat, ignition, and direct
sunlight. Protect cylinders against physical damage. Full and empty cylinders should be segregated. Use a first-in,
first-out inventory system to prevent full containers from being stored for long periods of time. These cylinders are
not refillable. WARNING! Do not refill DOT 39 cylinders. To do so may cause personal injury or property damage.
SPECIAL PRECAUTIONS FOR HANDLING GAS CYLINDERS: WARNING! Compressed gases can present significant
safety hazards. During cylinder use, use equipment designed for these specific cylinders. Ensure all lines and
equipment are rated for proper service pressure.
PROTECTIVE PRACTICES DURING MAINTENANCE OF CONTAMINATED EQUIPMENT: Follow practices indicated in
Section 6 (Accidental Release Measures). Make certain that application equipment is locked and tagged-out safely.
Always use product in areas where adequate ventilation is provided.
8. EXPOSURE CONTROLS - PERSONAL PROTECTION
VENTILATION AND ENGINEERING CONTROLS: Due to the presence of the Methyl Chloride component in this gas mixture,
refer to OSHA 29 CFR 1910.1051; 29 CFR 1910.19(1) for specific ventilation requirements. As with all chemicals, use this product
in well-ventilated areas. If this product is used in a poorly-ventilated area, install automatic monitoring equipment to detect the
levels of Isobutane and oxygen.
RESPIRATORY PROTECTION: No special respiratory protection is required under normal circumstances of use. Use supplied
air respiratory protection if the levels of Isobutane exceeds exposure limits presented in Section 2 (Composition and Information of
Ingredients) and Oxygen levels are below 19.5%, or unknown, during emergency response to a release of this product. If
respiratory protection is needed, use only protection authorized in the U.S. Federal OSHA Standard (29 CFR 1910.134),
applicable U.S. State regulations, or the Canadian CSA Standard Z94.4-93 and applicable standards of Canadian Provinces.
Oxygen levels below 19.16.33% are considered IDLH by OSHA. In such atmospheres, use of a full-facepiece pressure/demand
SCBA or a full facepiece, supplied air respirator with auxiliary self-contained air supply is required under OSHA鈥檚 Respiratory
Protection Standard (1910.134-1998). The following are NIOSH respiratory protection guidelines for Methyl Chloride:
METHYL CHLORIDE
CONCENTRATION RESPIRATORY PROTECTION
At Concentrations Above the NIOSH REL, or Where There is No REL, at Any Detectable Concentration: Any
Self-Contained Breathing Apparatus that has a full facepiece and is operated in a
pressure-demand or other positive-pressure mode, or any Supplied-Air Respirator
(SAR) that has a full facepiece and is operated in a pressure-demand or other positive-
pressure mode in combination with an auxiliary Self-Contained Breathing Apparatus
(SCBA) operated in pressure-demand or other positive-pressure mode.
Escape: Any appropriate escape-type, SCBA.
EYE PROTECTION: Safety glasses. If necessary, refer to U.S. OSHA 29 CFR 1910.133 or appropriate Canadian
Standards.
HAND PROTECTION: Wear leather gloves when handling cylinders. Chemically resistant gloves should be worn
when using this gas mixture. Polyvinyl Alcohol gloves are recommended. Natural rubber and neoprene gloves can
be dissolved after contact with Methyl Chloride. If necessary, refer to U.S. OSHA 29 CFR 1910.138 or appropriate
Standards of Canada.
BODY PROTECTION: No special protection is needed under normal circumstances of use. If a hazard of injury to the
feet exists due to falling objects, rolling objects, where objects may pierce the soles of the feet or where employee鈥檚
feet may be exposed to electrical hazards, use foot protection, as described in U.S. OSHA 29 CFR 1910.136.
9. PHYSICAL and CHEMICAL PROPERTIES
Unless otherwise specified, the following information is for Nitrogen, the main component of this gas
mixture.
3 3
GAS DENSITY @ 0掳C (32掳F) and 1 atm: .072 lb./ ft (1.153 kg/m ) BOILING POINT: -320.4掳F (-195.8掳C)
FREEZING/MELTING POINT @ 10 psig -210掳C (-345.8掳F) pH: Not applicable.
SPECIFIC VOLUME (ft3/lb): 13.8
SPECIFIC GRAVITY (air = 1) @ 21.1掳C (70掳F): 0.906
SOLUBILITY IN WATER vol/vol @ 0掳C (32掳F) and 1 atm: 0.023 MOLECULAR WEIGHT: 28.01
EVAPORATION RATE (nBuAc = 1): Not applicable. EXPANSION RATIO: Not applicable.
VAPOR PRESSURE @ 70掳F (21.1掳C) psig: Not applicable.
COEFFICIENT WATER/OIL DISTRIBUTION: Not applicable.
The following information is for this gas mixture.
ODOR THRESHOLD (values for Methyl Chloride): Odor Recognition in Air: 1.00x10+1 ppm (chemically pure).
APPEARANCE, ODOR AND COLOR: This is a colorless gas mixture with a faint sweet, ethereal odor.
HOW TO DETECT THIS SUBSTANCE (warning properties): There are no unusual warning properties associated with
a release of this product. The odor of Methyl Chloride is not a good warning property, as the odor threshold is
below the TLV.
10. STABILITY and REACTIVITY
STABILITY: Normally stable in gaseous state, under conditions of normal pressure and temperature.
DECOMPOSITION PRODUCTS: The Methyl Chloride component slowly reacts with water to form hydrochloric acid.
Products of thermal decomposition for Methyl Chloride include hydrogen chloride, carbon monoxide and
phosgene.
The Methyl Chloride component is incompatible with
MATERIALS WITH WHICH SUBSTANCE IS INCOMPATIBLE:
powdered aluminum, aluminum chloride, magnesium, zinc, sodium and other alkali metals.
HAZARDOUS POLYMERIZATION: Will not occur.
NON-FLAMMABLE GAS MIXTURE MSDS - 50067 EFFECTIVE DATE: APRIL 19, 2005
PAGE 3 OF6
11. TOXICOLOGICAL INFORMATION
CONDITIONS TO AVOID: Contact with incompatible materials. Cylinders exposed to high temperatures or direct
flame can rupture or burst.
TOXICITY DATA: The following toxicology data are available for the components of this product:
METHYL CHLORIDE: METHYL CHLORIDE (continued): METHYL CHLORIDE (continued):
LCLo (Inhalation-Human) 20, 000 ppm/2 TCLo (Inhalation-Rat) 1500 ppm/6 hours: TCLo (Inhalation-Mouse) 500 ppm/6 hours:
hours: Sense Organs and Special Senses female 7-19 day(s) after conception: female 6-17 day(s) after conception:
(Eye): effect, not otherwise specified; Reproductive: Effects on Embryo or Reproductive: Specific Developmental
Behavioral: convulsions or effect on Fetus: fetotoxicity (except death, e.g., Abnormalities: cardiovascular (circulatory)
seizure threshold; Gastrointestinal: stunted fetus); Specific Developmental system
nausea or vomiting Abnormalities: musculoskeletal system TCLo (Inhalation-Mouse) 500 ppm/6 hours:
LD50 (Oral-Rat) 1800 mg/kg TCLo (Inhalation-Rat) 3000 ppm/6 hours: female 6-18 day(s) after conception:
3
LC50 (Inhalation-Rat) 5300 mg/m /4 hours male 5 day(s) pre-mating: Reproductive: Reproductive: Effects on Embryo or
LC50 (Inhalation-Mouse) 2200 ppm/6 hours Paternal Effects: spermatogenesis (incl. Fetus: fetotoxicity (except death, e.g.,
LC50 (Inhalation-Dog) 14,661 ppm/6 hours: genetic material, sperm morphology, stunted fetus); Specific Developmental
Vascular: BP lowering not characterized motility, and count), testes, epididymis, Abnormalities: cardiovascular (circulatory)
in autonomic section; Lungs, Thorax, or sperm duct; Fertility: post-implantation system
Respiration: respiratory depression; mortality (e.g. dead and/or resorbed TCLo (Inhalation-Mouse) 500 ppm/6 hours:
Nutritional and Gross Metabolic: body implants per total number of implants) female 6-18 day(s) after conception:
temperature increase TCLo (Inhalation-Rat) 3000 ppm/6 hours: Reproductive: Specific Developmental
3
LCLo (Inhalation-Cat) 129 mg/m /4 hours: male 5 day(s) pre-mating: Reproductive: Abnormalities: cardiovascular (circulatory)
Behavioral: general anesthetic; Lungs, Fertility: male fertility index (e.g. # males system
Thorax, or Respiration: respiratory impregnating females per # males TCLo (Inhalation-Dog) 500 ppm/24 hours/3
depression exposed to fertile non-pregnant females) days-continuous: Brain and Coverings:
LCLo (Inhalation-Guinea Pig) 20,000 ppm/2 TCLo (Inhalation-Rat) 1500 ppm/6 hours: other degenerative changes; Behavioral:
hours female 7-20 day(s) after conception: tremor, ataxia
TCLo (Inhalation-Rat) 3000 ppm/6 hours/5 Reproductive: Maternal Effects: other Mutation Test Systems-not otherwise
days-intermittent: Nutritional and Gross effects; Effects on Embryo or Fetus: specified (Human-Lymphocyte) 3 pph
Metabolic: weight loss or decreased fetotoxicity (except death, e.g., stunted Sister Chromatid Exchange (Human-
weight gain; Related to Chronic Data: fetus) Lymphocyte) 3 pph
changes in testicular weight TCLo (Inhalation-Mouse) 150 ppm/22 Mutation in Mammalian Somatic Cells
3
TCLo (Inhalation-Rat) 41 mg/m /4 hours/26 hours/days-continuous: Behavioral: (Human-Lymphocyte) 5 pph
weeks-intermittent: Liver: liver function changes in motor activity (specific assay); Mutation in Microorganisms (Bacteria-
tests impaired; Blood: changes in Endocrine: changes in thymus weight; Salmonella typhimurium) 25,000 ppm
erythrocyte (RBC) count; Nutritional and Related to Chronic Data: death Phage Inhibition Capacity (Bacteria-
Gross Metabolic: weight loss or TCLo (Inhalation-Mouse) 1473 ppm/6 Escherichia coli) 5 pph
decreased weight gain hours/90 days-intermittent: Liver: liver Unscheduled DNA Synthesis (Rat-Sperm) 30
TCLo (Inhalation-Rat) 1473 ppm/6 hours/90 function tests impaired, changes in liver ppm/3 hours-continuous
days-intermittent: Liver: other changes; weight; Biochemical: Enzyme inhibition, Unscheduled DNA Synthesis (Rat-Liver) 1
Nutritional and Gross Metabolic: weight induction, or change in blood or tissue pph
loss or decreased weight gain levels: other transferases Dominant Lethal Test (Inhalation-Rat) 3000
TCLo (Inhalation-Rat) 997 ppm/6 hours/2 TCLo (Inhalation-Mouse) 997 ppm/6 hours/2 ppm/6 hours/5 days-continuous
years-intermittent: Tumorigenic: equivocal years-intermittent: Tumorigenic: Morphological Transformation (Hamster-
tumorigenic agent by RTECS criteria; Carcinogenic by RTECS criteria; Kidney, Embryo) 6 mL/plate
Reproductive: Tumorigenic effects: Ureter, Bladder: Kidney tumors NITROGEN:
testicular tumors TC (Inhalation-Mouse) 1000 ppm/6 hours/2 There are no specific toxicology data for
TCLo (Inhalation-Rat) 2000 ppm/6 hours: years-intermittent: Tumorigenic: equivocal Nitrogen. Nitrogen is a simple asphyxiant.
male 5 day(s) pre-mating: Reproductive: tumorigenic agent by RTECS criteria; OXYGEN:
Paternal Effects: spermatogenesis (incl. Kidney, Ureter, Bladder: tumors There are toxicity data for oxygen, but are
genetic material, sperm morphology, TCLo (Inhalation-Mouse) 750 ppm/6 hours: only related to exposure to oxygen in an
motility, and count) female 6-17 day(s) after conception: elevated pressure environment, such as a
TCLo (Inhalation-Rat) 1500 ppm/6 hours: Reproductive: Effects on Embryo or hyperbaric chamber.
male 50 day(s) pre-mating: Reproductive: Fetus: fetal death
Paternal Effects: testes, epididymis,
sperm duct
SUSPECTED CANCER AGENT: The components of this gas mixture are listed by agencies that track the cancer
potential of chemicals as follows:
METHYL CHLORIDE: ACGIH TLV-A4 (Not Classifiable as a Human Carcinogen); EPA-D (Not Classifiable as to Human Carcinogenicity); EPA-
CBD (Cannot Be Determined); IARC-3 (Unclassifiable as to Carcinogenicity in Humans); MAK-3B (Substances that Cause Concern that
They Could Be Carcinogenic for Man But Cannot Be Assessed Conclusively Because of Lack of Data. Substances for which in-vitro tests or
animal studies have yielded evidence of carcinogenic effects that is not sufficient for classification of the substance in one of the other
categories. Further studies are required before a final classification can be made. A MAK or BAT value can be established, provided no
genotoxic effects have been detected); NIOSH-Ca (Potential Occupational Carcinogen with No Further Categorization);
The remaining components of this gas mixture are not found on the following lists: U.S. FEDERAL OSHA Z LIST, NTP,
CAL/OSHA, and IARC; therefore are not considered to be, nor suspected to be, cancer-causing agents by these agencies.
IRRITANCY OF PRODUCT: This gas mixture is not anticipated to be irritating. Contact with rapidly escaping gas
from the cylinder can cause frostbite.
SENSITIZATION OF PRODUCT: No component of this gas mixture is known to be a skin or respiratory sensitizer.
REPRODUCTIVE TOXICITY INFORMATION: Listed below is information concerning the effects of this gas mixture and
its components on the human reproductive system.
Mutagenicity: This gas mixture is not expected to cause mutagenic effects in humans. The mutagenic activity of the Methyl
Chloride component has been measured in genotoxicity assays. In an established human lymphoblast line, a 3 hour
treatment with 0-5% Methyl Chloride resulted in a dose-related increase in mutant fraction at the thymidine kinase locus
and induction of sister-chromatid exchange. No increase in DNA damage, as measured by alkaline eluction, was detected
in the lymphoblasts at concentrations of Methyl Chloride shown to be mutagenic. Methyl Chloride is a weak, direct-acting
mutagen for bacteria and human cells in culture.
Embryotoxicity: This gas mixture is not expected to cause embryotoxic effects in humans.
Teratogenicity: This gas mixture is not expected to cause teratogenic effects in humans. The Methyl Chloride
component has caused teratogenic effects (malformed newborns) in animals. Female mice exposed to 500-750 ppm on
days 6-18 of pregnancy gave birth to pups with heart defects. Levels of 100-250 ppm had no effect. Maternal toxicity was
observed at the 750 ppm level but not at the 500 ppm level.
Reproductive Toxicity: This gas mixture is not expected to cause adverse reproductive effects in humans. In animal tests
involving Methyl Chloride, male rats exposed by inhalation to 3000 ppm for 6 hours/day, for 5 days, had
significantly reduced fertility. Exposure to 1000 ppm had no effect on fertility. No other paternal toxicity was reported.
In one study, exposure of male rats to 1000 ppm resulted in testicular damage, while, in another study, no testicular
damage was seen in rats exposed to 50, 225, or 1000 ppm.
A mutagen is a chemical which causes permanent changes to genetic material (DNA) such that the changes will propagate
through generation lines. An embryotoxin is a chemical which causes damage to a developing embryo (i.e. within the first eight
weeks of pregnancy in humans), but the damage does not propagate across generational lines. A teratogen is a chemical which
causes damage to a developing fetus, but the damage does not propagate across generational lines. A reproductive toxin is any
substance which interferes in any way with the reproductive process.
ACGIH BIOLOGICAL EXPOSURE INDICES (BEIs): Currently there are no ACGIH Biological Exposure Indices (BEIs)
applicable for this gas mixture鈥檚 components.
NON-FLAMMABLE GAS MIXTURE MSDS - 50067 EFFECTIVE DATE: APRIL 19, 2005
PAGE 4 OF6
12. ECOLOGICAL INFORMATION
ENVIRONMENTAL STABILITY: The components of this gas mixture occur naturally in the atmosphere. The gas
will be dissipated rapidly in well-ventilated areas. The following environmental data are available for the Methyl
Chloride component of this gas mixture.
METHYL CHLORIDE:
Terrestrial Fate: Based on a classification scheme, an estimated Koc value of 14, determined from a structure estimation method, indicates
that Methyl Chloride is expected to have very high mobility in soil. Volatilization of Methyl Chloride from moist soil surfaces is expected
to be an important fate process given a Henry's Law constant of 8.82X10-3 atm-cu m/mole. The potential for volatilization of Methyl
Chloride from dry soil surfaces may exist based upon a vapor pressure of 4.30X10+3 mm Hg. Field and laboratory results demonstrate
that several halogenated aliphatics may biodegrade slowly under anaerobic conditions, but not under aerobic conditions.
Aquatic Fate: Based on a classification scheme, an estimated Koc value of 14, determined from an estimation method indicates that Methyl
Chloride is not expected to adsorb to suspended solids and sediment. Volatilization from water surfaces is expected based upon a
Henry's Law constant of 8.82X10-3 atm-cu m/mole. Using this Henry's Law constant and an estimation method, volatilization half-lives
for a model river and model lake are 46 min and 3 days, respectively. According to a classification scheme, an estimated BCF of 3, from
its log Kow of 0.91 and a regression-derived equation, suggests the potential for bioconcentration in aquatic organisms is low. Field and
laboratory results demonstrate that several halogenated aliphatics may biodegrade slowly under anaerobic conditions, but not under
aerobic conditions.
Atmospheric Fate: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere, Methyl Chloride,
which has a vapor pressure of 4.30X10+3 mm Hg at 25掳C, is expected to exist solely as a gas in the ambient atmosphere. Gas-phase
Methyl Chloride is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals; the half-life for this reaction
in air is estimated to be 310 days, calculated from its rate constant of 5.3X10-14 cu cm/molecule-sec at 25掳C. The dominant loss
mechanism for Methyl Chloride in the troposphere is upward diffusion although washout by rain may also be important. From the
tropopause to about 30 km, both upward diffusion and reaction with hydroxyl radicals will be of approximately equal importance, and
above 30 km in the stratosphere diffusion, reaction with hydroxyl radicals, and photo-dissociation will have approximately equal weight.
The surface half-life resulting from upward diffusion is 80 days.
Bioconcentration: An estimated BCF of 3 was calculated for Methyl Chloride, using a log Kow of 0.91 and a regression-derived equation.
According to a classification scheme, this BCF suggests the potential for bioconcentration in aquatic organisms is low.
NITROGEN:
Water Solubility = 2.4 volumes Nitrogen/100 volumes water at 0掳C; 1.6 volumes Nitrogen/100 volumes water at 20掳C.
OXYGEN:
Water Solubility = 1 volume Oxygen/32 volumes water at 20掳C. Log Kow = -0.65
EFFECT OF MATERIAL ON PLANTS or ANIMALS: No evidence is currently available on the effects of this
product on plants or animals.
EFFECT OF CHEMICAL ON AQUATIC LIFE: No evidence is currently available on the effects of this product on
aquatic life. The following are aquatic toxicity data for the Methyl Chloride component of this gas mixture:
METHYL CHLORIDE: METHYL CHLORIDE:
EC0 (Pseudomonas putida bacteria) 16 hours = 500 mg/L LC50 (Lepomis macrochirus) 96 hours = 550 ppm (static bioassay in
EC50,S (Methanogenic bacteria) 24 hours = 39 mg/L fresh water at 23掳C, mild aeration applied after 24 hours)
EC0 (Microcystis aeruginosa algae) 8 days = 550 mg/L LC50 (Menidia beryllina) 96 hours = 270 ppm (static bioassay in
EC0 (Scenedesmus quadricauda algae) 7days = 1,450 mg/L synthetic seawater at 23掳 C, mild aeration applied after 24 hours)
EC0 (Entosiphon sulcatum protozoa) 72 hours = 8,000 mg/L
13. DISPOSAL CONSIDERATIONS
PREPARING WASTES FOR DISPOSAL PREPARING WASTES FOR DISPOSAL: Waste disposal must be in
accordance with appropriate U.S. Federal, State, and local regulations, or the applicable standards of Canada and
its Provinces. Cylinders with undesired residual product may be safely vented outdoors with the proper regulator.
For further information, refer to Section 16 (Other Information).
14. TRANSPORTATION INFORMATION
THIS GAS MIXTURE IS HAZARDOUS AS DEFINED BY 49 CFR 172.101 BY THE U.S. DEPARTMENT OF
TRANSPORTATION.
PROPER SHIPPING NAME: Compressed gases, n.o.s. (Oxygen, Methyl Chloride, Nitrogen)
HAZARD CLASS NUMBER and DESCRIPTION: 2.2 (Non-Flammable Gas)
UN IDENTIFICATION NUMBER: UN 1956
PACKING GROUP: Not Applicable
DOT LABEL(S) REQUIRED: Non-Flammable Gas
NORTH AMERICAN EMERGENCY RESPONSE GUIDEBOOK NUMBER (2000): 126
MARINE POLLUTANT: The components of this gas mixture are not classified by the DOT as Marine Pollutants
(as defined by 49 CFR 172.101, Appendix B).
SPECIAL SHIPPING INFORMATION: Cylinders should be transported in a secure position, in a well-ventilated
vehicle. The transportation of compressed gas cylinders in automobiles or in closed-body vehicles can present
serious safety hazards. If transporting these cylinders in vehicles, ensure these cylinders are not exposed to
extremely high temperatures (as may occur in an enclosed vehicle on a hot day). Additionally, the vehicle
should be well-ventilated during transportation.
Note: DOT 39 Cylinders ship in a strong outer carton (overpack). Pertinent shipping information goes on the
outside of the overpack. DOT 39 Cylinders do not have transportation information on the cylinder itself.
TRANSPORT CANADA TRANSPORTATION OF DANGEROUS GOODS REGULATIONS: This gas mixture is
considered as Dangerous Goods, per regulations of Transport Canada. The use of the above U.S. DOT
information from the U.S. 49 CFR regulations is allowed for shipments that originate in the U.S.
For shipments via ground vehicle or rail that originate in Canada, the following information is applicable.
PROPER SHIPPING NAME: Compressed gases, n.o.s. (Oxygen, Methyl Chloride, Nitrogen)
HAZARD CLASS NUMBER and DESCRIPTION: Class 2.2 (Non-Flammable Gas)
UN IDENTIFICATION NUMBER: UN 1956
PACKING GROUP: Not Applicable
HAZARD LABEL(S) REQUIRED: Class 2.2 (Non-Flammable Gas)
SPECIAL PROVISIONS: None
EXPLOSIVE LIMIT & LIMITED QUANTITY INDEX: 0.12
ERAP INDEX: 0
PASSENGER CARRYING SHIP INDEX: None
PASSENGER CARRYING ROAD OR RAIL VEHICLE INDEX: 75
MARINE POLLUTANT: Not applicable.
NON-FLAMMABLE GAS MIXTURE MSDS - 50067 EFFECTIVE DATE: APRIL 19, 2005
PAGE 5 OF6
15. REGULATORY INFORMATION
ADDITIONAL U.S. REGULATIONS:
U.S. SARA REPORTING REQUIREMENTS: The components of this product are subject to the reporting
requirements of Sections 302, 304, and 313 of Title III of the Superfund Amendments and Reauthorization Act, as
follows:
CHEMICAL NAME SARA 302 SARA 304 SARA 313
(40 CFR 355, Appendix (40 CFR Table 302.4) (40 CFR 372.65)
A)
Methyl Chloride No No Yes
U.S. SARA THRESHOLD PLANNING QUANTITY: There are no specific Threshold Planning Quantities for this
material. The default Federal MSDS submission and inventory requirement filing threshold of 10,000 lb (4,540 kg)
may apply, per 40 CFR 370.20.
U.S. CERCLA REPORTABLE QUANTITY (RQ) : Methyl Chloride = 100 lb (45.4 kg)
U.S. TSCA INVENTORY STATUS: The components of this gas mixture are on the U.S. TSCA Inventory.
OTHER U.S. FEDERAL REGULATIONS:
鈥? The Methyl Chloride component of this gas mixture is subject to the reporting requirements of Section 112(r) of
the Clean Air Act. The reportable quantity (RQ) of Methyl Chloride under this regulation is 10,000 lb (4550
kg). Methyl Chloride listed as a Hazardous Air Pollutant (HAP) generally known or suspected to cause
serious health problems.
鈥? This gas mixture does not contain any Class I or Class II ozone depleting chemicals (40 CFR part 82).
U.S. STATE REGULATORY INFORMATION: The components of this gas mixture are covered under the following
specific State regulations:
Alaska - Designated Toxic and Hazardous Michigan - Critical Materials Register: No. Pennsylvania - Hazardous Substance List:
Methyl Chloride, Nitrogen.
Substances: Methyl Chloride. Minnesota - List of Hazardous Substances:
Methyl Chloride. Rhode Island - Hazardous Substance List:
California - Permissible Exposure Limits
Methyl Chloride, Nitrogen.
Missouri - Employer Information/Toxic
for Chemical Contaminants: Methyl
Texas - Hazardous Substance List: Methyl
Chloride, Nitrogen. Substance List: Methyl Chloride.
Chloride.
Florida - Substance List: Methyl Chloride. New Jersey - Right to Know Hazardous
West Virginia - Hazardous Substance List:
Illinois - Toxic Substance List: Methyl Substance List: Methyl Chloride, Nitrogen.
Methyl Chloride.
Chloride. North Dakota - List of Hazardous
Wisconsin - Toxic and Hazardous
Kansas - Section 302/313 List: Methyl Chemicals, Reportable Quantities: None.
Substances: Methyl Chloride.
Chloride.
Massachusetts - Substance List: Methyl
Chloride.
The Methyl Chloride
CALIFORNIA SAFE DRINKING WATER AND TOXIC ENFORCEMENT ACT (PROPOSITION 65):
component of this gas mixture is on the California Proposition 65 lists. WARNING! This gas mixture contains a
compound that is known to the State of California to cause reproductive harm.
ADDITIONAL CANADIAN REGULATIONS:
CANADIAN DSL/NDSL INVENTORY STATUS: The components of this product are on the Canadian DSL Inventory.
OTHER CANADIAN REGULATIONS: Not applicable.
CANADIAN ENVIRONMENTAL PROTECTION ACT (CEPA) PRIORITIES SUBSTANCES LISTS: The components of this
product are not on the CEPA Priorities Substances List.
CANADIAN WHMIS CLASSIFICATION: This gas mixture is categorized as a Controlled Product, Hazard Class A, D2B,
as per the Controlled Product Regulations.
16. OTHER INFORMATION
INFORMATION ABOUT DOT-39 NRC (Non-Refillable Cylinder) PRODUCTS
DOT 39 cylinders ship as hazardous materials when full. Once the cylinders are relieved of pressure (empty) they are not
considered hazardous material or waste. Residual gas in this type of cylinder is not an issue because toxic gas mixtures are
prohibited. Calibration gas mixtures typically packaged in these cylinders are Nonflammable n.o.s., UN 1956. A small
percentage of calibration gases packaged in DOT 39 cylinders are flammable or oxidizing gas mixtures.
For disposal of used DOT-39 cylinders, it is acceptable to place them in a landfill if local laws permit. Their disposal is no
different than that employed with other DOT containers such as spray paint cans, household aerosols, or disposable cylinders
of propane (for camping, torch etc.). When feasible, we recommended recycling for scrap metal content. CALGAZ, LLC will
do this for any customer that wishes to return cylinders to us prepaid. All that is required is a phone call to make arrangements
so we may anticipate arrival. Scrapping cylinders involves some preparation before the metal dealer may accept them. We
perform this operation as a service to valued customers who want to participate.
MIXTURES: When two or more gases or liquefied gases are mixed, their hazardous properties may combine to create
additional, unexpected hazards. Obtain and evaluate the safety information for each component before you produce the
mixture. Consult an Industrial Hygienist or other trained person when you make your safety evaluation of the end product.
Remember, gases and liquids have properties which can cause serious injury or death.
Further information about the handling of compressed gases can be found in the following pamphlets published by:
Compressed Gas Association Inc. (CGA), 1725 Jefferson Davis Highway, Suite 1004, Arlington, VA 22202-4102. Telephone:
(703) 412-0900.
P-1 鈥淪afe Handling of Compressed Gases in Containers鈥?
AV-1 鈥淪afe Handling and Storage of Compressed Gases鈥?
鈥淗andbook of Compressed Gases鈥?
PREPARED BY: CHEMICAL SAFETY ASSOCIATES, Inc.
PO Box 3519, La Mesa, CA 91944-3519
619/670-0609
Fax on Demand: 1-800/231-1366
This Material Safety Data Sheet is offered pursuant to OSHA鈥檚 Hazard Communication Standard, 29 CFR, 1910.1200. Other government
regulations must be reviewed for applicability to this product. To the best of CALGAZ, LLC鈥檚 knowledge, the information contained herein is
reliable and accurate as of this date; however, accuracy, suitability or completeness are not guaranteed and no warranties of any type, either
express or implied, are provided. The information contained herein relates only to this specific product. If this product is combined with other
materials, all component properties must be considered. Data may be changed from time to time. Be sure to consult the latest edition.
NON-FLAMMABLE GAS MIXTURE MSDS - 50067 EFFECTIVE DATE: APRIL 19, 2005
PAGE 6 OF6
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