EMS CATALOG NO: 10100
EMS PRODUCT: Acrolein
DATE: 03/04/2001
PAGE NUMBER: One of 5
MATERIAL SAFETY DATA SHEET
The information contained herein is based on data considered
accurate. However, no warranty is expressed or implied
regarding the accuracy of these data or the results to be
obtained from the use thereof.
Electron Microscopy Sciences assumes no responsibility for
personal injury or property damage to vendees, users or
third parties caused by the material. Such vendees or users
assume all risks associated with the use of the material.
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FOR PRODUCT AND SALES INFORMATION
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CONTACT ELECTRON MICROSCOPY SCIENCES OFFICE ABOVE.
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PRODUCT IDENTIFICATION
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PRODUCT NAME: Acrolein
CAS NO. 107-02-8
MOLECULAR FORMULA: C3H40
ADDITIONAL INFO: Contains Hydroquinone (HQ) Chemical Abstracts
Registry number 123031-9. This compound is listed
as a carcinogen or potential carcinogen by
National Toxicology Program.
SYNONYM(S):
Acquinite, Acraldehyde, Acraldehydeacroleina (Italian),
Transacrolein, Acroleina Acrolein (ACGIH, OSHA), Acroleine
(Dutch, French), Acrolein Inhibited (DOT), Acrylaldehyd
(German), Acrylaldehyde, Acrylic Aldehyde, Akrolein (Czech),
Akroleina (Polish), Aldehyde Acrylique (French), Aldeide
Acrilica (Italian), Allyl Aldehyde, Aqualin, Aqualine, Biocide,
Crolean, Ethylene Aldehyde, Magnacide, H, NSC 8819, Propenal,
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2-Propenal, Prop-2-EN-1-AL, 2-Propen-1-One, Propylene Aldehyde,
RCRA Waste No. P003, Slimicide, UN 1092 (DOT)
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HAZARDS IDENTIFICATION
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LABEL PRECAUTIONARY STATEMENTS:
FLAMMABLE (USA DEFINITION)
HIGHLY FLAMMABLE (EUROPEAN DEFINITION)
HIGHLY TOXIC (USA DEFINITION)
VERY TOXIC (EUROPEAN DEFINITION)
MAY CAUSE CANCER.
VERY TOXIC BY INHALATION, IN CONTACT WITH SKIN AND IF SWALLOWED.
CAUSES BURNS.
MAY CAUSE SENSITIZATION BY SKIN CONTACT. SEVERE LACHRYMATOR.
TARGET ORGAN(s):
LIVER, CARDIOVASCULAR SYSTEM.
KEEP AWAY FROM SOURCES OF IGNITION, NO SMOKING.
DO NOT EMPTY INTO DRAINS.
TAKE PRECAUTIONARY MEASURES AGAINST STATIC DISCHARGES.
IN CASE OF ACCIDENT OR IF YOU FEEL UNWELL, SEEK MEDICAL ADVICE
IMMEDIATELY SHOW THE LABEL WHERE POSSIBLE.
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FIRST AID
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In case of contact, immediately flush eyes or skin with copious
amounts of water for at least 15 minutes while removing
contaminated clothing and shoes. Assure adequate flushing of the
eyes by separating the eyelids with fingers.
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
If swallowed, wash out mouth with water provided person is
conscious. Call physician immediately. Discard contaminated
clothing and shoes.
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FIRE FIGHTING MEASURES
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EXTINGUISHING MEDIA:
Carbon dioxide, dry chemical powder or appropriate foram. Water
may be effective for cooling, but may not effect extinguishment.
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SPECIAL FIREFIGHTING PROCEDURES:
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
UNUSUAL FIRE AND EXPLOSIONS HAZARDS:
EXTREMELY FLAMMABLE. Vapor may travel considerable distance to
source of ignition and flash back.
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ACCIDENTAL RELEASE MEASURES
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Evacuate area. Shut off all sources of ignition. Wear self-
contained breathing apparatus, rubber boots and heavy rubber
gloves. Cover with an activated carbon absorbent, take up and
place in closed containers. Transport outdoors. Ventilate area
and wash spill site after material pickup is complete.
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EXPOSURE CONTROLS/PERSONAL PROTECTION
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Wear appropriate NIOSH/MSHA-approved respirator, chemical-
resistant gloves, safety goggles, other protective clothing.
Safety shower and eye bath. Use only in a chemical fume hood.
Faceshield (8-inch minimum). Do not breathe vapor. Do not get
in eyes, on skin, on clothing Avoid prolonged or repeated
exposure. Readily absorbed through skin. Wash thoroughly after
handling. Highly Toxic. Corrosive. Severe lachrymator.
Carcinogen. Keep tightly closed. Keep away from heat, sparks,
and open flame. Heat- and light-sensitive. Refrigerate.
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PHYSICAL & CHEMICAL PROPERTIES
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BOILING POINT: 53oC
MELTING POINT: -87oC
FLASHPOINT: -2oF / 16oC
AUTOIGNITION TEMP: 428oF / 219oC
UPPER EXPLOSION LEVEL: 31%
LOWER EXPLOSION LEVEL: 2.8%
SPECIFIC GRAVITY: 0.839
VAPOR PRESSURE: 4.05 PSI @ 20oC / 15.82 PSI @ 55oC
VAPOR DENSITY: 1.94
SPECIFIC GRAVITY: 0.839
APPEARANCE AND ODOR: Colorless liquid.
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STABILITY AND REACTIVITY
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INCOMPATIBILITIES:
Bases; Oxidizing agents; Reducing agents; Oxygen.
May polymerize on exposure to light. Sensitive to heat
HAZARDOUS COMBUSTION OR DECOMPOSITION PRODUCTS:
TOXIC FUMES OF:
Carbon Monoxide, Carbon Dioxide.
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TOXICOLOGICAL INFORMATION
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ACUTE EFFECTS:
May be fatal if inhaled, swallowed, or absorbed through skin.
Material is extremely destructive to tissue of the mucous
membranes and upper respiratory tract, eyes and skin. Inhalation
may be fatal as a result of spasm, inflammation and edema of the
larynx and bronchi, chemical pneumonitis and pulmonary edema.
Symptoms of exposure may include burning sensation, coughing,
wheezing, laryngitis, shortness of breath, headache, nausea and
vomiting. May cause allergic skin reaction.
CHRONIC EFFECTS: CARCINOGEN
TARGET ORGANS:
Liver; Cardiovascular System; Lungs; Eyes; Kidneys.
RTECS NO.: AS1050000
IRRITATION DATA:
EYE-HMN 500 PPB/12M IAPWAR 4,79,61
SKN-RBT 5 Mg Open Sev UCDS** 6/18/71
SKN-RBT 2 Mg/24H Sev 85JCAE -,268,86
EYE-RBT 1 Mg Sev UCDS** 6/18/71
EYE-RBT 50 UG/24H Sev 85JCAE -,268,86
TOXICITY DATA:
IHL-HMN LCLO:5500 PPB 34ZIAG -,73,69
IHL-HMN LCLO:153 PPM/10M NTIS** PB214-270
ORL-RAT LD50:46 Mg/Kg FMCHA2 -,C24,89
IHL-RAT LC50:18500 Ug/M3/4H HUTODJ 8,229,89
IPR-RAT LD50:4 Mg/Kg TXAPA9 71,84,83
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SCU-RAT LD50:50 Mg/Kg APTOA6 6,299,50
ORL-MUS LD50:40 Mg/Kg BIJOAK 34,1196,40
IHL-MUS LC50:66 PPM/6H IAANBS 26,281,70
IPR-MUS LD50:9008 Ug/Kg NCISP* JAN86
SCU-MUS LD50:30 Mg/Kg APTOA6 6,299,50
ORL-RBT LD50:7 Mg/Kg PCOC**-,1,66
SKN-RBT LD50:562 Mg/Kg WRPCA2 9,119,70
UNR-MAM LD50:45 Mg/Kg 30ZDA9 -,111,71
TARGET ORGAN DATA:
Sense organs and special senses (Lacrimation)
Behavioral (General Anesthetic)
Behavioral (Convulsions or effect on seizure threshold)
Lungs, Thorax or Respiration (Change in Trachea or Bronchi)
Lungs, Thorax or Respiration (Respiratory obstruction)
Lungs, Thorax or Respiration (Other changes)
Liver (Fatty liver degeneration)
Blood (other changes)
Effects on Fertility (Post-implantation Mortality)
Tumorigenic (Active as anti-cancer agent)
Only selected registry of toxic effects of chemical
substances (RTECS) Data is presented here. See actual entry
in RTECS for complete information.
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DISPOSAL CONSIDERATIONS
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Burn in a chemical incinerator equipped with an afterburner and
scrubber but exert extra care in igniting as this material is
highly flammable. Observe all Federal, State and local laws.
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REGULATORY INFORMATION
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TLV & SOURCE FOR HYDROQUINONE: ACGIH TLV-TWA: 2 MG/M3
OSHA PEL FINAL: 8 HR TWA 2 MG/M3
REVIEWS, STANDARDS, AND REGULATIONS:
ACGIH TLV-TWA 0.1 PPM; STEL 0.3 PPM 85INA8 6,21,91
IARC Cancer Review:
Animal Inadequate Evidence IMEMDT 19,479,79
Animal Inadequate Evidence IMEMDT 36,133,85
Human Inadequate Evidence IMEMDT 36,133,85
Human Inadequate Evidence IMEMDT 63,337,95
Group 3 IMSUDL 7,78,87
Group 3 IMEMDT 63,339,95
EPA FIFRA 1988 Pesticide subject to registration or re-
registration FEREAC 54,7740,89
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MSHA Standard Air: TWA 0.1 PPM (0.25 Mg/M3) DTLVS* 3,5,71
OSHA PEL: 8H TWA 0.1 PPM (0.25 Mg/M3) FEREAC 54,2923,89
OSHA PEL Final: 8H TWA 0.1 PPM (0.25 Mg/M3);STEL 0.3 PPM
(0.8 Mg/m3) FEREAC 54,2923,89
NOHS 1974: HZD 03530: NIS 16; TNF 845; NOS 25; TNE 7299
NOES 1983: HZD 03530; NIS 4; TNF 37; NOS 18; TNE 1298;TFE 5
EPA TSCA Chemical Inventory, 9
EPA TSCA Test Submission (TSCATS) Data Base, October 1995
NIOSH Analytical Methods: See Acrolein, 2501
NTP Carcinogenesis Studies; On test(Prechronic Studies) July 1995
OSHA Analytical Method #52
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