SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 28/JUN/2005
Date Updated: 24/NOV/2004
Version 1.4
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name CONGO RED, CERTIFIED (C.I. 22120)
Product Number 860956
Company Sigma-Aldrich Pty. Ltd.
12 Anella Avenue
Castle Hill NSW 2154
Australia
Technical Phone # +61 2 9841 0555 (1800 800 097)
Fax +61 2 9841 0500 (1800 800 096)
Emergency Phone # +44 8701906777 (1800 448 465)
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
CONGO RED 573-58-0 209-358-4 611-027-00-8
Formula C32H22N6Na2O6S2
Molecular Weight 696.67 AMU
Synonyms Atlantic Congo Red * Atul Congo Red * Azocard
Red Congo * Benzo Congo Red * Brasilamina congo
4B * Cerven kongo (Czech) * Cerven prima 28
(Czech) * C.I. 22120 * C.I. Direct Red 28 * C.I.
Direct Red 28, disodium salt * Congo Red * Congo
Red 4B * Congo Red 4BX * Congo Red CR * Congo
Red H * Congo Red ICI * Congo Red L * Congo Red
M * Congo Red N * Congo Red R * Congo Red RS *
Congo Red W * Cotton Red 5B * Cotton Red 4BC *
Cotton Red L * Diacotton Congo Red * Direct Red
28 * Direct Red C * Direct Red DC-CF * Direct
Red K * Erie Congo 4B * Haemonorm * Hemorrhagyl
* Hispamin congo 4B * Kayaku Congo Red *
Kongorot (German) * Mitsui Congo Red * Peeramine
Congo Red * Red K * Sodium
diphenyldiazo-bis(alpha-naphthylaminesulfonate)
* Sugai Congo Red * Tertrodirect Red C *
Trisulfon Congo Red * Vondacel Red CL *
Natrium-salz der
diphenyl-bis-azo-bis-naphthylamin-4-sulfonsaeure
(German)
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
May cause cancer. Possible risk of harm to the unborn child.
Carc. Cat.2 Repr. Cat.3
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If breathing becomes difficult,
call a physician.
AFTER SKIN CONTACT
In case of contact, immediately wash skin with soap and copious
amounts of water.
AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.
SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves. Wear disposable coveralls and discard them after
use.
METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Avoid
raising dust. Ventilate area and wash spill site after material
pickup is complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe dust. Do not get in
eyes, on skin, on clothing. Avoid prolonged or repeated exposure.
STORAGE
Conditions of Storage: Keep tightly closed.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Use only in a chemical fume hood. Safety shower and eye bath.
GENERAL HYGIENE MEASURES
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Wash contaminated clothing before reuse. Wash thoroughly after
handling.
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator in
nonventilated areas and/or for exposure above the TLV or PEL.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
9 - Physical and Chemical Properties
Appearance Physical State: Solid
Property Value At Temperature or Pressure
pH 6.7 20 掳C Concentration: 10
g/l
BP/BP Range N/A
MP/MP Range 360 掳C
Flash Point N/A
Flammability N/A
Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure N/A
SG/Density N/A
Partition Coefficient N/A
Viscosity N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density 600 - 700 kg/l
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility Solubility in Water:25 mg/ml H2O
Other Solvents: ETHANOL, ACETONE INSOLUBLE
IN ETHER
10 - Stability and Reactivity
STABILITY
Stable: Stable.
Materials to Avoid: Strong oxidizing agents.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide,
Nitrogen oxides, Sulfur oxides.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
RTECS NUMBER: QK1400000
ACUTE TOXICITY
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LDLO
Oral
Man
143 mg/kg
Remarks: Vascular:Other changes.
LDLO
Intravenous
Man
1429 UG/KG
Remarks: Behavioral:Convulsions or effect on seizure threshold.
Lungs, Thorax, or Respiration:Dyspnea. Blood:Change in clotting
factors.
LD50
Oral
Rat
15200 mg/kg
IRRITATION DATA
Eyes
Rabbit
100 mg
Remarks: Moderate irritation effect
SIGNS AND SYMPTOMS OF EXPOSURE
To the best of our knowledge, the chemical, physical, and
toxicological properties have not been thoroughly investigated.
ROUTE OF EXPOSURE
Skin Contact: Causes skin irritation.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: Causes eye irritation.
Inhalation: Material is irritating to mucous membranes and upper
respiratory tract. May be harmful if inhaled.
Ingestion: May be harmful if swallowed.
CHRONIC EXPOSURE - CARCINOGEN
Result: This product is or contains a component that has been
reported to be probably carcinogenic based on its IARC, OSHA,
ACGIH, NTP, or EPA classification.
CHRONIC EXPOSURE - MUTAGEN
Rat
10 UMOL/L
Cell Type: liver
Unscheduled DNA synthesis
Rat
300 MG/KG
Cell Type: S. typhimurium
Body fluid assay
Mouse
192 UMOL/KG
Skin
DNA
Hamster
10 UMOL/L
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Cell Type: liver
Unscheduled DNA synthesis
CHRONIC EXPOSURE - TERATOGEN
Result: Possible risk of congenital malformation in the fetus.
Species: Rat
Dose: 200 MG/KG
Route of Application: Intraperitoneal
Exposure Time: (9D PREG)
Result: Specific Developmental Abnormalities: Central nervous
system. Specific Developmental Abnormalities: Eye, ear. Specific
Developmental Abnormalities: Urogenital system.
Species: Rat
Dose: 200 MG/KG
Route of Application: Intraperitoneal
Exposure Time: (8D PREG)
Result: Effects on Embryo or Fetus: Other effects to embryo.
Species: Mouse
Dose: 5 GM/KG
Route of Application: Oral
Exposure Time: (8-12D PREG)
Result: Specific Developmental Abnormalities: Urogenital system.
Effects on Newborn: Germ cell effects (in offspring). Effects on
Newborn: Delayed effects.
Species: Mouse
Dose: 300 MG/KG
Route of Application: Intraperitoneal
Exposure Time: (8D PREG)
Result: Specific Developmental Abnormalities: Urogenital system.
CHRONIC EXPOSURE - REPRODUCTIVE HAZARD
Species: Rat
Dose: 140 MG/KG
Route of Application: Intraperitoneal
Exposure Time: (9D PREG)
Result: Effects on Fertility: Post-implantation mortality (e.g.,
dead and/or resorbed implants per total number of implants).
Species: Rat
Dose: 140 MG/KG
Route of Application: Intraperitoneal
Exposure Time: (8D PREG)
Result: Effects on Fertility: Post-implantation mortality (e.g.,
dead and/or resorbed implants per total number of implants).
Species: Mouse
Dose: 5 GM/KG
Route of Application: Oral
Exposure Time: (MULTIGENERATION)
Result: Effects on Fertility: Female fertility index (e.g., #
females pregnant per # sperm positive females; # females
pregnant per # females mated ).
Species: Mouse
Dose: 5 GM/KG
Route of Application: Oral
Exposure Time: (8-12D PREG)
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Result: Effects on Newborn: Growth statistics (e.g., reduced
weight gain). Effects on Newborn: Physical.
Species: Mouse
Dose: 2500 UG/KG
Route of Application: Oral
Exposure Time: (MULTIGENERATION)
Result: Paternal Effects: Spermatogenesis (including genetic
material, sperm morphology,motility, and count). Paternal
Effects: Testes, epididymis, sperm duct.
Species: Mouse
Dose: 5 GM/KG
Route of Application: Oral
Exposure Time: (8-12D PREG)
Result: Effects on Newborn: Other postnatal measures or effects.
Species: Mouse
Dose: 1500 MG/KG
Route of Application: Intraperitoneal
Exposure Time: (8-12D PREG)
Result: Effects on Newborn: Growth statistics (e.g., reduced
weight gain). Effects on Newborn: Physical.
CMR CAT.: Carc. Cat.2
12 - Ecological Information
No data available.
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Observe all federal, state, and local
environmental regulations.
14 - Transport Information
RID/ADR
Non-hazardous for road transport.
IMDG
Non-hazardous for sea transport.
IATA
Non-hazardous for air transport.
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
ANNEX I INDEX NUMBER: 611-027-00-8
INDICATION OF DANGER: T
Toxic.
R-PHRASES: 45 63
May cause cancer. Possible risk of harm to the unborn child.
S-PHRASES: 53 45
Restricted to professional users. Attention - Avoid exposure -
obtain special instructions before use. In case of accident or
if you feel unwell, seek medical advice immediately (show the
label where possible).
16 - Other Information
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WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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