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Biomolecules for research                             MATERIAL SAFETY DATA SHEET







Section 1 : Substance Identification



               Capsaicin

     Name:                                                    CAS Number:        404-86-4



     Catalog Number:       EI-125                             Chemical Formula:       C18H27NO3



     Chemical Name:      8-Methyl-N-vanillyl-6-nonenamide



     Chemical Class:     Nonenamide



     Company Identification:        BIOMOL International L.P.

                                    5120 Butler Pike

                                    Plymouth Meeting PA 19462-1202 USA

                                    (610) 941-0430 (9am-5pm ET)









Section 2 : Health Hazard Data



     Acute Health Effects:      This compound may be toxic if ingested, inhaled or absorbed through the skin.

     This compound is irritating to the eyes, skin, mucous membranes, and upper respiratory tract. May cause

     itching, lachrymation, inflammation, sneezing, or vomiting

     Chronic Health Effects:      This chemical is classified by IARC as a Group 2B carcinogen.







Section 3 : First Aid Measures



     Eye Contact: Check for and remove contact lenses. Flush eyes with running water for at least 15

             minutes separating eyelids. Seek medical attention immediately

     Skin Contact:      Remove contaminated clothing and shoes. Wash with soap and water for 15 minutes.

             Bath or immerse the irritated area in vinegar (5% acetic acid). Immersion should be continued as

             long as irritation is felt upon drying the affected area. Several hours immersion may be necessary

             in severe cases. An alternative treatment involves the immersion of the effected area in vegetable

             oil. Seek medical attention.

     Inhalation: Remove from exposure. If breathing is difficult, administer oxygen. If breathing stops,

             administer artificial respiration. Seek medical attention immediately. Provide chemical label

             and MSDS if possible.

      Ingestion: Remove dentures and clear mouth. If person is conscious, induce vomiting. Call

              physician or poison control immediately. Provide chemical label and MSDS information if

              possible.









Section 4 : Fire and Explosion Data





      Flammability: Combustible

      Flash Point: Not Available

      Combustion Products: Carbon dioxide, Carbon monoxide, Nitrogen oxides

      Extinguishing Media: Carbon Dioxide, Dry chemical powder, polymer foam, water spray

      Special Firefighting Procedures: Use self-contained breathing apparatus and protective clothing to

              prevent contact with skin and eyes.

      Unusual Fire/Explosion Hazards: None known









 Section 5 : Spill or Leak Procedures



      Cleanup Procedures: EVACUATE AREA Wearing appropriate protective gear as outlined under

               "Protective equipment" wipe up spill and place in sealed container and hold for disposal. Avoid

      raising dust. Ventilate the area and wash spill site thoroughly after material has been removed.

      Waste Disposal Method:         Observe all Federal, State and Local regulations concerning the disposal of

               this product.









 Section 6 : Storage and Handling Precautions



      Protective Equipment: For spill clean up, wear suitable protective clothing, chemical resistant rubber

              gloves, rubber boots, and chemical safety goggles. Self contained breathing apparatus or

              NIOSH/MSHA approved respirator is required.

      Storage and Handling: This product should be stored at room temperature. It should be kept in a tightly

              closed container. This product should be handled only by qualified experienced professionals.

              Wash thoroughly after handling this material









Section 7 : Physical Data



      Appearance: Off-white solid                                      Odor: Not Available

      Molecular Weight: 305.4                                          Taste: Burning

      Boiling Point: 210-220°C @ 0.01 mm Hg                            Melting Point: 62-65°C

      Solubility: Methanol, Ethanol, Ether, Chloroform                 Vapor Density: Not Available

      Specific Gravity: Not Available                                  Vapor Pressure: Not Available

      Volatility: Not Available

Section 8 : Stability and Reactivity Data



         Stability: This material is stable if stored as directed

         Conditions to Avoid: Excessive heat or light

         Incompatibles: Strong oxidizing agents







Section 9 : Toxicity Data



         RTECS#:         RA8530000



         I.P. LD50:                   Rat : 9500µg/kg              Mouse : 6500 µg/kg

                                      Rabbit : >50mg/kg

         Oral LD50:                   Mouse : 47200µg/kg





Section 10 : Ecological Data



         Ecotoxicological Information: None Available







The above information is believed to be correct but does not purport to be complete and should be used only as a guide. The burden of

safe use of this material rests entirely with the user.





Emergency Contact:



BIOMOL International L.P.

5120 Butler Pike

Plymouth Meeting, PA 19462 USA



(610) 941-0430







Last Revised : 1/12/04