EC SAFETY DATA SHEET 2001/58/EG
_______________________________________________________________________________________________
Product name Crotonaldehyde EUGB/EN
MSDS number 80560 Revision Date Feb.02.2007
Revision Number 2.00 Issuing date Feb.02.2007
_______________________________________________________________________________________________
1. Identification of the substance/preparation and the company/undertaking
Product name
Crotonaldehyde
Manufacturer, importer, supplier
Celanese Chemicals Europe GmbH
Frankfurter Stra遝 111
D-61476 Kronberg/Ts.
Product Information
Product Stewardship FAX +49 (0) 208 693 2053
Emergency telephone number
+49 (0) 69-305 6418
End use:
Chemical intermediate (including monomers)
2. Composition/information on ingredients
Chemical characterization 2-Butenal, 3-Methylacroleine (also CAS-No. 123-73-9, EINECS-No. 204-647-1).
Components CAS-No EC-No. Classification Percent %
Crotonaldehyde 4170-30-3 224-030-0 F;R11 > 99.0
Muta. Cat.3;R68
N;R50
T+;R26
T;R24/25
Xi;R37/38-41
Xn;R48/22
3. Hazards identification
Indication of danger Highly flammable
Dangerous for the environment
Very Toxic
R-phrase(s)
R11 - Highly flammable.
R26 - Very toxic by inhalation.
R41 - Risk of serious damage to eyes.
R50 - Very toxic to aquatic organisms.
R68 - Possible risks of irreversible effects.
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EC SAFETY DATA SHEET 2001/58/EG
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Product name Crotonaldehyde EUGB/EN
MSDS number 80560 Revision Date Feb.02.2007
Revision Number 2.00 Issuing date Feb.02.2007
_______________________________________________________________________________________________
R24/25 - Toxic in contact with skin and if swallowed.
R37/38 - Irritating to respiratory system and skin.
R48/22 - Harmful: danger of serious damage to health by prolonged exposure if
swallowed.
Statements of hazard In addition to the EC classification based on Celanese data this product should also
be regarded as:
corrosive
May cause sensitization by skin contact
4. First aid measures
General Information Remove contaminated, soaked clothing immediately and dispose of safely.
Inhalation Keep at rest. Aerate with fresh air. If symptoms persist, call a physician.
Skin Wash off immediately with soap and plenty of water. If symptoms persist, call a
physician.
Eyes Rinse immediately with plenty of water, also under the eyelids, for at least 15
minutes. Call a physician immediately.
Ingestion Call a physician immediately. Do not induce vomiting without medical advice.
Notes to physician
Main symptoms Shortness of breath.
Special hazard Lung oedema.
Treatment Treat symptomatically. In case of lung irritation first treatment with dexametason
aerosol (spray).
5. Fire-fighting measures
Suitable extinguishing media
alcohol-resistant foam. Dry chemical. carbon dioxide (CO2).
Extinguishing media which must not be used for safety reasons
Do not use a solid water stream as it may scatter and spread fire.
Special exposure hazards arising from the substance or preparation itself, its combustion products, or released
gases
Under conditions giving incomplete combustion, hazardous gases produced may consist of
carbon monoxide
carbon dioxide (CO2)
Combustion gases of organic materials must in principle be graded as inhalation poisons
vapors are heavier than air and may spread along floors
Special protective equipment for fire-fighters
self-contained breathing apparatus (EN 133).
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Product name Crotonaldehyde EUGB/EN
MSDS number 80560 Revision Date Feb.02.2007
Revision Number 2.00 Issuing date Feb.02.2007
_______________________________________________________________________________________________
Environmental precautions
Dike and collect water used to fight fire.
Other Information
Cool containers / tanks with water spray.
6. Accidental release measures
Personal precautions
Provide adequate ventilation. Avoid contact with the skin and the eyes. Keep away from heat and sources of ignition.
Environmental precautions
Prevent further leakage or spillage. Do not discharge into the drains/surface waters/groundwater.
Methods for cleaning Up
Soak up with inert absorbent material. Do not use rags, paper towels or combustible materials to clean up a spill, because
spontaneous combustion can occur. Keep in suitable, closed containers for disposal. Dispose of in accordance with local
regulations.
7. Handling and storage
Handling
Advice on safe handling
Provide sufficient air exchange and/or exhaust in work rooms. Refill and handle product only in closed system.
Protection - fire and explosion:
Keep away from sources of ignition - No smoking. Take necessary action to avoid static electricity discharge.
Ground and bond containers when transferring material. In case of fire, emergency cooling with water spray should
be available. Vapours are heavier than air and may spread along floors.
Temperature class
T4
Storage
Technical measures/Storage conditions
Keep tightly closed in a dry, cool and well-ventilated place. Handle and open container with care. Store under
nitrogen.
Incompatible products
strong acids. oxidizing agents. strong bases.
German storage class
3A: Flammable liquids.
8. Exposure controls / personal protection
National occupational exposure limits
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Product name Crotonaldehyde EUGB/EN
MSDS number 80560 Revision Date Feb.02.2007
Revision Number 2.00 Issuing date Feb.02.2007
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No exposure limits established.
Engineering measures General or dilution ventilation is frequently insufficient as the sole means of
controlling employee exposure. Local ventilation is usually preferred. Explosion-proof
equipment (for example fans, switches, and grounded ducts) should be used in
mechanical ventilation systems.
Personal protective equipment
General advice Avoid contact with skin and eyes. Do not breathe vapors or spray mist. Use only in
an area equipped with a safety shower. Hold eye wash fountain available.
Hygiene measures When using, do not eat, drink or smoke. Take off all contaminated clothing
immediately. Wash hands before breaks and immediately after handling the product.
Respiratory protection respirator with A filter. Full mask with above mentioned filter according to producers
using requirements or self-contained breathing apparatus. Equipment should
conform to EN 136 or EN 140 and EN 143.
Eye protection tightly fitting safety goggles. In addition to goggles, wear a face shield if there is a
reasonable chance for splash to the face. Equipment should conform to EN 166.
skin protection impervious clothing
Hand protection
Chemicals resistant gloves
Suitable material butyl-rubber
Type Butylplus (Company COMASEC) or comparable article;
or refer to glove manufacturer's recommendation
Evaluation according to EN 374: level 4
Material thickness approx 0.3 mm
Break through time approx 120 min
9. Physical and chemical properties
Appearance
Form liquid
Colour yellowish
Odor pungent
Molecular Weight 70.09
Flash point 13癈
Method closed cup
Ignition temperature 155癈
Method DIN 51794
Lower explosion limit 2.1 Vol. %
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Product name Crotonaldehyde EUGB/EN
MSDS number 80560 Revision Date Feb.02.2007
Revision Number 2.00 Issuing date Feb.02.2007
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Upper explosion limit 15.5 Vol. %
Melting point/range -76.5癈
Boiling point/range 102癈 @ 1013 hPa
Density 0.85 g/ml @ 20癈
vapor pressure 40 hPa @ 25癈
vapor density 2.41 (Air=1 @ 20 癈)
Water solubility 150 g/l @ 20癈
Partition coefficient 0.60 (calculated)
(n-octanol/water)
10. Stability and reactivity
Stability Stable under normal conditions of handling, use and transportation.
Conditions to avoid Avoid any source of ignition. Avoid contact with heat, sparks, open flame, and static
discharge.
Materials to avoid Keep away from:, strong acids, oxygen, oxidizing agents, bases, amines.
Thermal decomposition No decomposition if used as directed. If heated to thermal decomposition the
following decomposition products may occur depending on the conditions. carbon
oxides.
Hazardous reactions May form explosive peroxides. Polymerization can occur. Polymerization is a highly
exothermic reaction and may generate sufficient heat to cause thermal
decomposition and/or rupture containers.
11. Toxicological information
Crotonaldehyde
Oral LD50: 174 - 300 mg/kg, rat
Dermal LD50: 324 mg/kg, rabbit
Inhalation LC50: 0.2 mg/l, rat, 2h
Skin irritation corrosive
Species rabbit
Method Exposure time: 4 h occluded treatment
Skin Sensitization moderate sensitizer
Species Human experience
Eye Irritation corrosive
Species rabbit eye
Carcinogenic effects Induced neoplastic lesions of the liver in 9 of 27 animals and
precancerous altered liver foci in 23 of 27 animals
Species rats
Study oral (drinking water) lifetime study
LOAEL: 0.6 mM
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Product name Crotonaldehyde EUGB/EN
MSDS number 80560 Revision Date Feb.02.2007
Revision Number 2.00 Issuing date Feb.02.2007
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in vitro Mutagenicity Ames test - positive
Induces DNA-protein cross-links
Induces DNA adducts in primary rat liver, CHO and human
cells
in vivo Mutagenicity Induces sex-linked recessive mutations and chromosome
translocations in the fruit fly by injection
Reproductive toxicity Induces damage to mouse spermatogonial cells and
anueploidy by oral and IP treatment
Repeated exposure 90-day Damage of forestomach including necrosis at a dose
of >= 10 mg/kg/day
Routes of exposure oral gavage
Species rats
NOAEL: 5 mg/kg/day
Species mice
NOAEL: 20 mg/kg/d
12. Ecological information
Crotonaldehyde
Toxicity to fish LC50: 3.5 mg/l (96h)
Species Lepomis macrochirus (Bluegill sunfish)
Method static conditions
LC50: 0.96 mg/l (96h)
Species Pimephales promelas (Fathead minnow)
Method Flow-through
Toxicity to daphnia EC50: 1.8 mg/l (48h)
Species Daphnia magna
Toxicity to algae EC50: 0.88 mg/l (48h)
Species Selenastrum capricornutum (green algae)
Biodegradation 37 % (5d)
Bioconcentration factor (BCF) -0.17
13. Disposal considerations
Product information Disposal required in compliance with all waste management related state and local
regulations. The choice of the appropriate method of disposal depends on the
product composition by the time of disposal as well as the local statutes and
possibilities for disposal.
Uncleaned empty packaging Contaminated packaging should be emptied as far as possible and after appropriate
cleansing may be taken for reuse.
14. Transport information
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Product name Crotonaldehyde EUGB/EN
MSDS number 80560 Revision Date Feb.02.2007
Revision Number 2.00 Issuing date Feb.02.2007
_______________________________________________________________________________________________
14. Transport information
ADR/RID
UN/ID No. UN 1143
Proper Shipping Name Crotonaldehyde
Hazard Class 6.1
Subsidiary Risk 3
Packing group I
Hazard Number 663
ADNR ADNR: Container and Tanker
UN/ID No. UN 1143
Proper Shipping Name Crotonaldehyde
Hazard Class 6.1
Subsidiary Risk 3
Packing group I
ICAO/IATA forbidden
IMDG
UN/ID No. UN 1143
Proper Shipping Name Crotonaldehyde
Hazard Class 6.1
Subsidiary Risk 3
Packing group I
Marine pollutant Yes
EmS Code F-E, S-D
15. Regulatory information
Labelling in accordance with EC directives
EC label
Contains Crotonaldehyde
Symbol(s) F - Highly flammable.
T+ - Very toxic.
N - Dangerous for the environment.
R-phrase(s)
R11 - Highly flammable.
R26 - Very toxic by inhalation.
R41 - Risk of serious damage to eyes.
R50 - Very toxic to aquatic organisms.
R68 - Possible risks of irreversible effects.
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Product name Crotonaldehyde EUGB/EN
MSDS number 80560 Revision Date Feb.02.2007
Revision Number 2.00 Issuing date Feb.02.2007
_______________________________________________________________________________________________
R24/25 - Toxic in contact with skin and if swallowed.
R37/38 - Irritating to respiratory system and skin.
R48/22 - Harmful: danger of serious damage to health by prolonged exposure if
swallowed.
S-phrase(s)
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek
medical advice.
S28.2 - After contact with skin, wash immediately with plenty of soap and water.
S61 - Avoid release to the environment. Refer to special instructions/Safety data
sheets.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Directive 1996/82/EC Annex I, part 2:
No 1
No 7b
No 9i
Water Hazard Class (WGK):
WGK Class 3
WGK Reg-Nr. 239
WGK Source Classification according to VwVwS, Annex 1 or 2
Crotonaldehyde 4170-30-3
Directive 76/769/EEC Listed.
Directive 98/24/EC Listed.
Regulatory Information This classification following EG guidelines is also in accordance with the Chemicals
(Hazard Information and Packaging for Supply) Regulation CHIP (as amended).
16. Other information
R-phrase(s)
R11 - Highly flammable.
R26 - Very toxic by inhalation.
R41 - Risk of serious damage to eyes.
R50 - Very toxic to aquatic organisms.
R68 - Possible risk of irreversible effects
R24/25 - Toxic in contact with skin and if swallowed.
R37/38 - Irritating to respiratory system and skin.
R48/22 - Harmful: danger of serious damage to health by prolonged exposure if swallowed.
For further information, see:
For more information, other material safety data sheets or technical data sheets please consult the Celanese homepage
(www.celanese.com).
Other Information:
Observe national and local legal requirements.
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EC SAFETY DATA SHEET 2001/58/EG
_______________________________________________________________________________________________
Product name Crotonaldehyde EUGB/EN
MSDS number 80560 Revision Date Feb.02.2007
Revision Number 2.00 Issuing date Feb.02.2007
_______________________________________________________________________________________________
Changes against the previous version are marked by ***
Sources of key data used to compile the datasheet
Information contained in this safety data sheet is based on Celanese owned data and public sources deemed valid or
acceptable. The absence of data elements required by ANSI or 2001/58/EC indicates, that no data meeting these
requirements is available.
Further information
This information is based on our present state of knowledge. It shall describe our products regarding safety requirements
and shall not be construed as a guarantee or statement of condition and/or quality
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