MATERIAL SAFETY DATA SHEET Page 1 of 7
MATERIAL SAFETY DATA SHEET
3-Chloroaniline, 99%
33858
**** SECTION 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION ****
MSDS Name: 3-Chloroaniline, 99%
Synonyms:
None
Company Identification: Acros Organics N.V.
One Reagent Lane
Fairlawn, NJ 07410
For information in North America, call: 800-ACROS-01
For emergencies in the US, call CHEMTREC: 800-424-9300
**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
| 108-42-9 |3-Chloroaniline | 99.0 | 203-581-0 |
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols: T C N
Risk Phrases: 33 34 24/25 50/53
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Appearance: Not available.
Danger! May cause allergic skin reaction. Corrosive. Light
sensitive. Air sensitive. May cause central nervous system
depression. May be absorbed through the skin. May cause
methemoglobinemia. Causes eye and skin burns. May cause liver and
kidney damage. May cause respiratory and digestive tract irritation.
May cause cancer based on animal studies. Harmful if inhaled or
swallowed. Potential cancer hazard. May cause skin eruptions and/or
acne.
Target Organs: Blood, kidneys, central nervous system, liver.
Potential Health Effects
Eye:
Causes eye burns.
Skin:
Causes skin burns. Substance is rapidly absorbed through the skin.
If absorbed, may cause symptoms similar to those for ingestion.
Ingestion:
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Harmful if swallowed. May cause irritation of the digestive tract.
May cause liver and kidney damage. May cause methemoglobinemia,
cyanosis, convulsions, and death. Methemoglobinemia is characterized
by dizziness, drowsiness, headache, breath shortness, cyanosis with
bluish skin, rapid heart rate and chocolate-brown colored blood. May
cause central nervous system effects. May cause discoloration of the
lips, tongue, and mucous membranes.
Inhalation:
Harmful if inhaled. May cause respiratory tract irritation. May
cause effects similar to those described for ingestion.
Chronic:
May cause cancer according to animal studies.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Immediately flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower lids. Get medical aid
immediately.
Skin:
Get medical aid. Flush skin with plenty of soap and water for at
least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Get medical aid immediately. Induce vomiting by giving one teaspoon
of Syrup of Ipecac. Do NOT induce vomiting. Allow the victim to rinse
his mouth and then to drink 2-4 cupfuls of water, and seek medical
advice.
Inhalation:
Get medical aid immediately. Remove from exposure to fresh air
immediately. If breathing is difficult, give oxygen. DO NOT use
mouth-to-mouth respiration. If breathing has ceased apply artificial
respiration using oxygen and a suitable mechanical device such as a
bag and a mask.
Notes to Physician:
Treat symptomatically and supportively.
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion.
Extinguishing Media:
In case of fire use water spray, dry chemical, carbon dioxide, or
chemical foam. Do NOT use straight streams of water.
Autoignition Temperature: 500 deg C ( 932.00 deg F)
Flash Point: 190 deg C ( 374.00 deg F)
(estimated) Health: 2; Flammability: 0; Reactivity: 0
Explosion Limits, Lower: Not available.
Upper: Not available.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Absorb spill with inert material, (e.g., dry sand or earth), then
place into a chemical waste container. Clean up spills immediately,
observing precautions in the Protective Equipment section. Provide
ventilation.
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MATERIAL SAFETY DATA SHEET Page 3 of 7
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Use with adequate ventilation. Do not get in eyes,
on skin, or on clothing. Keep container tightly closed. Do not ingest
or inhale.
Storage:
Keep container closed when not in use. Store in a tightly closed
container. Store in a cool, dry, well-ventilated area away from
incompatible substances.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits
+--------------------+-------------------+-------------------+-----------------+
| Chemical Name | ACGIH | NIOSH |OSHA - Final PELs|
|--------------------|-------------------|-------------------|-----------------|
| 3-Chloroaniline |2 ppm TWA; 7.6 |NIOSH Potential |5 ppm TWA; 19 |
| | mg/m3 TWA |Occupational | mg/m3 TWA |
| |(listed under | Carcinogen - see | (listed under |
| |ANILINE).skin - |Appendix A | ANILINE). |
| |potential for |(listed under | |
| |cutaneous | | |
| |absorption | | |
| |(listed under | | |
| |ANILINE). | | |
+--------------------+-------------------+-------------------+-----------------+
OSHA Vacated PELs:
3-Chloroaniline:
2 ppm TWA; 8 mg/m3 TWA (listed under ANILINE)
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to minimize
contact with skin.
Respirators:
Follow the OSHA respirator regulations found in 29CFR
1910.134 or European Standard EN 149. Always use a
NIOSH or European Standard EN 149 approved respirator
when necessary.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Liquid
Appearance: Not available.
Odor: None reported.
pH: Not available.
Vapor Pressure: 0.05 mm Hg @20C
Vapor Density: Not available.
Evaporation Rate: Not available.
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MATERIAL SAFETY DATA SHEET Page 4 of 7
Viscosity: Not available.
Boiling Point: 229.8 deg C
Freezing/Melting Point: -10.4 deg C
Decomposition Temperature: 190 deg C
Solubility: Insoluble.
Specific Gravity/Density: 1.2060g/cm3
Molecular Formula: C6H6ClN
Molecular Weight: 127.57
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable under normal temperatures and pressures. Substance may
undergo color change upon exposure to light and air.
Conditions to Avoid:
Incompatible materials, strong oxidants.
Incompatibilities with Other Materials:
Acids, acid chlorides, acid anhydrides, strong oxidizing agents,
chloroformates.
Hazardous Decomposition Products:
Hydrogen chloride, nitrogen oxides, carbon monoxide, carbon dioxide,
nitrogen.
Hazardous Polymerization: Will not occur.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 108-42-9: BX0350000
LD50/LC50:
CAS# 108-42-9: Inhalation, mouse: LC50 =550 mg/m3/4H; Oral, mouse:
LD50 = 334 mg/kg; Oral, rat: LD50 = 256 mg/kg; Skin, rat: LD50 = 250
mg/kg.
Carcinogenicity:
3-Chloroaniline -
ACGIH: A3 - Animal Carcinogen (listed as ANILINE).
California: carcinogen - initial date 1/1/90 (listed as ANILINE).
NIOSH: occupational carcinogen (listed as ANILINE)
OSHA: Possible select carcinogen (listed as ANILINE).
IARC: Group 3 carcinogen (listed as ANILINE).
Epidemiology:
No data available.
Teratogenicity:
No data available.
Reproductive Effects:
No data available.
Neurotoxicity:
No data available.
Mutagenicity:
No data available.
Other Studies:
No data available.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
Ecotoxicity:
Not available.
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
RCRA D-Series Maximum Concentration of Contaminants:
None listed.
RCRA D-Series Chronic Toxicity Reference Levels: None
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MATERIAL SAFETY DATA SHEET Page 5 of 7
listed.
RCRA F-Series: None listed.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Not listed as a material banned from land disposal
according to RCRA.
**** SECTION 14 - TRANSPORT INFORMATION ****
US DOT
Shipping Name: CHLOROANILINES, LIQUID
Hazard Class: 6.1
UN Number: 2019
Packing Group: II
IMO
Shipping Name: CHLOROANILINES, LIQUID
Hazard Class: 6.1
UN Number: 2019
Packing Group: II
IATA
Shipping Name: CHLOROANILINES, LIQUID
Hazard Class: 6.1
UN Number: 2019
Packing Group: II
RID/ADR
Shipping Name: CHLOROANILINES, LIQUID
Dangerous Goods Code: 6.1(12B)
UN Number: 2019
Canadian TDG
Shipping Name: CHLOROANILINE
Hazard Class: 6.1
UN Number: UN2019
**** SECTION 15 - REGULATORY INFORMATION ****
US FEDERAL
TSCA
CAS# 108-42-9 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
Section 302 (RQ)
None of the chemicals in this material have an RQ.
Section 302 (TPQ)
None of the chemicals in this product have a TPQ.
Section 313
This material contains 3-Chloroaniline (listed as ANILINE), 99 0%,
(CAS# 108-42-9) which is subject to the reporting requirements of
Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
CAS# 108-42-9 listed as ANILINE is listed as a hazardous air
pollutant (HAP).
This material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
CAS# 108-42-9 is listed as a Hazardous Substance under the CWA.
None of the chemicals in this product are listed as Priority
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MATERIAL SAFETY DATA SHEET Page 6 of 7
Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants
under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous
by OSHA.
STATE
3-Chloroaniline can be found on the following state right to know
lists: California, (listed as ANILINE), New Jersey, (listed as
ANILINE), Florida, (listed as ANILINE), Pennsylvania, (listed as
ANILINE), Minnesota, (listed as ANILINE), Massachusetts, (listed as
ANILINE).
The following statement(s) is(are) made in order to comply with
the California Safe Drinking Water Act:
WARNING: This product contains 3-Chloroaniline, listed as `ANILINE',
a chemical known to the state of California to cause cancer.
California No Significant Risk Level:
CAS# 108-42-9: no significant risk level = 100 ug/day (listed
under ANILINE)
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T C N
Risk Phrases:
R 33 Danger of cumulative effects.
R 34 Causes burns.
R 24/25 Toxic in contact with skin and if swallowed.
R 50/53 Very toxic to aquatic organisms; may cause
long-term adverse effects in the aquatic environment.
Safety Phrases:
S 36/37 Wear suitable protective clothing and
gloves.
S 45 In case of accident of if you feel unwell, seek
medical advice immediately (show the label where
possible).
S 60 This material and/or its container must be
disposed of as hazardous waste.
S 28A After contact with skin, wash immediately with
plenty of water.
S 61 Avoid release to the environment. Refer to
special instructions/Safety data sheets.
WGK (Water Danger/Protection)
CAS# 108-42-9: 2
Canada
CAS# 108-42-9 is listed on Canada's DSL/NDSL List.
This product does not have a WHMIS classification.
CAS# 108-42-9 is not listed on Canada's Ingredient Disclosure List.
Exposure Limits
CAS# 108-42-9 (listed as aniline): OEL-ARAB Republic of Egypt:TWA 2 pp
m (10 mg/m3);Skin. OEL-AUSTRALIA:TWA 2 ppm (10 mg/m3);Skin. OEL-AUSTRI
A:TWA 2 ppm (8 mg/m3);Skin. OEL-BELGIUM:TWA 2 ppm (7.6 mg/m3);Skin. OE
L-CZECHOSLOVAKIA:TWA 5 mg/m3;STEL 20 mg/m3 JAN9. OEL-DENMARK:TWA 1 ppm
(4 mg/m3);Skin. OEL-FINLAND:TWA 2 ppm (7.6 mg/m3);STEL 4 ppm (15 mg/m
3);Skin;CAR. OEL-FRANCE:TWA 2 ppm (10 mg/m3);Skin. OEL-GERMANY:TWA 2 p
pm (8 mg/m3);Skin;Carcinogen. OEL-HUNGARY:TWA 5 mg/m3;STEL 10 mg/m3;Sk
in. OEL-INDIA:TWA 0.2 mg/m3;Skin. OEL-JAPAN:TWA 1 ppm (3.8 mg/m3);Skin
. OEL-THE NETHERLANDS:TWA 5 ppm (19 mg/m3);Skin. OEL-THE PHILIPPINES:T
WA 5 ppm (19 mg/m3);Skin. OEL-POLAND:TWA 5 mg/m3;STEL 20 mg/m3;Skin. O
EL-RUSSIA:TWA 1 ppm;STEL 0.1 mg/m3;Skin. OEL-SWEDEN:TWA 1 ppm (4 mg/m3
);STEL 2 ppm (8 mg/m3);Skin. OEL-SWITZERLAND:TWA 2 ppm (8 mg/m3);STEL
10 ppm (40 mg/m3);Skin. OEL-TURKEY:TWA 5 ppm (19 mg/m3);Skin. OEL-UNIT
ED KINGDOM:TWA 2 ppm (10 mg/m3);STEL 5 ppm;Skin. OEL IN BULGARIA, COLO
MBIA, JORDAN, KOREA check ACGIH TLV. OEL IN NEW ZEALAND, SINGAPORE, VI
ETNAM check ACGI TLV
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MATERIAL SAFETY DATA SHEET Page 7 of 7
**** SECTION 16 - ADDITIONAL INFORMATION ****
MSDS Creation Date: 4/09/1991 Revision #3 Date: 5/14/1998
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall Fisher be liable
for any claims, losses, or damages of any third party or for lost profits
or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if Fisher has been advised of
the possibility of such damages.
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