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Section 1 - Chemical Product and Company Identification |
MSDS Name: 2-Butanone oxime, 99%
Catalog Numbers:
AC403330000, AC403330250, AC403331000
Synonyms:
Ethyl methyl ketone oxime; Ethyl methyl ketoxime; 2-Butanone oxime;
Methyl ethyl ketoxime; MEK-oxime.
Company Identification:
Acros Organics N.V.
One Reagent Lane
Fair Lawn, NJ 07410
For information in North America, call: 800-ACROS-01
For emergencies in the US, call CHEMTREC: 800-424-9300
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Section 2 - Composition, Information on Ingredients
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| CAS# |
Chemical Name |
Percent |
EINECS/ELINCS |
| 96-29-7 |
Methyl ethyl ketoxime |
99 | 202-496-6 |
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Section 3 - Hazards Identification
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EMERGENCY OVERVIEW
Appearance: clear colorless to pale yellow. Flash Point: 59 deg C.
Warning! Causes severe eye irritation.
Flammable liquid and vapor. May cause allergic skin
reaction.
Target Organs: Blood, liver, eyes, skin.
Potential Health Effects
Eye:
Causes severe eye irritation.
Skin:
Harmful if absorbed through the skin. May cause skin sensitization,
an allergic reaction, which becomes evident upon re-exposure to this
material.
Ingestion:
Methemoglobinemia is characterized by dizziness, drowsiness,
headache, shortness of breath, cyanosis (bluish discoloration of skin
due to deficient oxygenation of the blood), rapid heart rate and
chocolate-brown colored blood. May be harmful if swallowed.
Overexposure may cause methemoglobinemia.
Inhalation:
Not available.
Chronic:
Chronic exposure may cause liver damage.
The major target organ of methyl ethyl ketoxime is the red blood
cell.; the no-effect level for erythrotoxicity is 625 ppm in male
rats and 312 ppm in female rats based on erythrocyte counts after 13
weeks of exposure. The no-effect level for hematopoietic toxicity is
312 ppm in rats based on erythroid cell hyperplasia in bone marrow
and 2,500 ppm in mice based on hematopoietic cell proliferation in
the spleen. Hematology results of this drinking water study indicate
that methyl ethyl ketoxime induces a methemoglobinemia and a
responsive Heinz body anemia. Methyl ethyl ketoxime was at most
weakly
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Section 4 - First Aid Measures
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Eyes:
Flush eyes with plenty of water for at least 15 minutes, occasionally
lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15
minutes while removing contaminated clothing and shoes. Remove
contaminated clothing and shoes.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh
air immediately. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen.
Notes to Physician:
Treat symptomatically.
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Section 5 - Fire Fighting Measures
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General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion. Flammable
liquid and vapor. Vapors are heavier than air and may travel to a
source of ignition and flash back. Vapors can spread along the ground
and collect in low or confined areas.
Extinguishing Media:
Use extinguishing media most appropriate for the surrounding fire.
Flash Point: 59 deg C ( 138.20 deg F)
Autoignition Temperature: Not available.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating:
(estimated) Health: 2; Flammability: 2; Instability: 1
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Section 6 - Accidental Release Measures
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General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container. Clean up spills immediately,
observing precautions in the Protective Equipment section. Remove all
sources of ignition. Provide ventilation.
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Section 7 - Handling and Storage
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Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Avoid contact with eyes, skin, and clothing. Avoid
ingestion and inhalation. Use only with adequate ventilation. Keep
away from heat, sparks and flame.
Storage:
Keep away from sources of ignition. Keep container closed when not
in use. Store in a cool, dry, well-ventilated area away from
incompatible substances.
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Section 8 - Exposure Controls, Personal Protection
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Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use process enclosure,
local exhaust ventilation, or other engineering controls to control
airborne levels.
Exposure Limits
| Chemical Name |
ACGIH |
NIOSH |
OSHA - Final PELs |
| Methyl ethyl ketoxime
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none listed
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none listed
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none listed
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OSHA Vacated PELs:
Methyl ethyl ketoxime:
No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes:
Wear chemical splash goggles.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
A respiratory protection program that meets OSHA's 29
CFR 1910.134 and ANSI Z88.2 requirements or European
Standard EN 149 must be followed whenever workplace
conditions warrant respirator use.
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Section 9 - Physical and Chemical Properties
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Physical State: Clear liquid
Appearance: clear colorless to pale yellow
Odor: Not available.
pH: Not available.
Vapor Pressure: 0.904 mm Hg @ 25 deg C
Vapor Density: 3.0 (air=1)
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 152.5 deg C @ 760 mm Hg
Freezing/Melting Point:-29.5 deg C
Decomposition Temperature:Not available.
Solubility: Slightly soluble.
Specific Gravity/Density:.9200 g/cm3
Molecular Formula:C4H9NO
Molecular Weight:87.12
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Section 10 - Stability and Reactivity
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Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
High temperatures, ignition sources.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong acids.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported
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Section 11 - Toxicological Information
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RTECS#:
CAS# 96-29-7:
EL9275000
LD50/LC50:
CAS# 96-29-7:
Draize test, rabbit,
eye: 100 uL Severe;
Oral, mouse:
LD50 = 1 gm/kg;
Oral, rat: LD50 =
930 mg/kg;
Skin, rabbit: LD50 =
200 uL/kg;
.
Skin, rabbit: LD50 = 200 uL/kg = 184 mg/kg.
Carcinogenicity:
CAS# 96-29-7:
Not listed by ACGIH, IARC, NTP, or CA Prop 65.
Epidemiology:
No data available.
Teratogenicity:
No data available.
Reproductive Effects:
No data available.
Mutagenicity:
See actual entry in RTECS for complete information.
Neurotoxicity:
No data available.
Other Studies:
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Section 12 - Ecological Information
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No information available.
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Section 13 - Disposal Considerations
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Chemical waste generators must determine whether a discarded chemical is classified
as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3.
Additionally, waste generators must consult state and local hazardous waste regulations to
ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
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Section 14 - Transport Information
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| |
US DOT |
Canada TDG |
| Shipping Name: |
FLAMMABLE LIQUIDS, N.O.S. |
No information available. |
| Hazard Class: |
3 |
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| UN Number: |
UN1993 |
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| Packing Group: |
III |
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Section 15 - Regulatory Information
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US FEDERAL
TSCA
CAS# 96-29-7 is listed on the TSCA inventory.
Health & Safety Reporting List
CAS# 96-29-7: Effective 12/15/86, Sunset 12/19/95
Chemical Test Rules
CAS# 96-29-7: 40 CFR 799.2700
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants.
This material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product
are listed as Hazardous Substances under the CWA.
None of the chemicals in this
product are listed as Priority Pollutants under the CWA.
None of the chemicals in this
product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product
are considered highly hazardous by OSHA.
STATE
CAS# 96-29-7 can be found on the
following state right to know lists: Minnesota.
California Prop 65
California No Significant Risk Level:
None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
XN
Risk Phrases:
R 21 Harmful in contact with skin.
R 40 Limited evidence of a carcinogenic effect.
R 41 Risk of serious damage to eyes.
R 43 May cause sensitization by skin contact.
Safety Phrases:
S 13 Keep away from food, drink and animal feeding stuffs.
S 23 Do not inhale gas/fumes/vapour/spray.
S 26 In case of contact with eyes, rinse immediately with plenty of
water and seek medical advice.
S 36/37/39 Wear suitable protective clothing, gloves and eye/face pr
otection.
WGK (Water Danger/Protection)
CAS# 96-29-7: 1
Canada - DSL/NDSL
CAS# 96-29-7 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of D2B, B3.
This product has been classified in accordance with the hazard
criteria of the Controlled Products Regulations and the MSDS
contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
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Section 16 - Additional Information
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MSDS Creation Date: 5/20/1999
Revision #5 Date: 3/15/2007
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no event shall Fisher be liable
for any claims, losses, or damages of any third party or for lost profits
or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if Fisher has been advised of
the possibility of such damages.
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