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MSDS  
:
 l-Adrenaline, 97% (titr.)
CAS  
:
 51-43-4
SYNONYMS  
:
 l-3,4-Dihydroxy-?1-(methylaminomethyl)benzyl alcohol; Adrenaline

Section 1 - Chemical Product and Company Identification
MSDS Name: l-Adrenaline, 97% (titr.)
Catalog Numbers: AC400380000, AC400380010, AC400380050, AC400380100
Synonyms:
l-3,4-Dihydroxy-?1-(methylaminomethyl)benzyl alcohol; Adrenaline
Company Identification:

              Acros Organics N.V.
              One Reagent Lane
              Fair Lawn, NJ 07410
For information in North America, call: 800-ACROS-01
For emergencies in the US, call CHEMTREC: 800-424-9300

Section 2 - Composition, Information on Ingredients

CAS# Chemical Name Percent EINECS/ELINCS
51-43-4 L(-)-Epinephrine, 99% 200-098-7

Section 3 - Hazards Identification

EMERGENCY OVERVIEW

Appearance: slightly grey fine powder.
Target Organs: None.


Potential Health Effects The toxicological properties of this material have not been investigated. Use appropriate procedures to prevent opportunities for direct contact with the skin or eyes and to prevent inhalation.

Section 4 - First Aid Measures


Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids.
Skin: Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion: Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation: Remove from exposure and move to fresh air immediately.
Notes to Physician: Treat symptomatically.

Section 5 - Fire Fighting Measures


General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media: In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
Flash Point: Not available.
Autoignition Temperature: Not available.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: ; Flammability: ; Instability:

Section 6 - Accidental Release Measures


General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Sweep up, then place into a suitable container for disposal.

Section 7 - Handling and Storage


Handling: Not available.
Storage: Keep refrigerated. (Store below 4C/39F.)

Section 8 - Exposure Controls, Personal Protection


Engineering Controls: Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits
Chemical Name ACGIH NIOSH OSHA - Final PELs
L(-)-Epinephrine, 99% none listed none listed none listed

OSHA Vacated PELs: L(-)-Epinephrine, 99%: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear safety glasses and chemical goggles if splashing is possible.
Skin: Wear appropriate protective gloves and clothing to prevent skin exposure.
Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators: Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.

Section 9 - Physical and Chemical Properties


Physical State: Crystalline powder
Appearance: white to light beige
Odor: none reported
pH: Not available.
Vapor Pressure: Not available.
Vapor Density: Not available.
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point:208-211 C
Decomposition Temperature:Not available.
Solubility: Not available.
Specific Gravity/Density:Not available.
Molecular Formula:C9H13NO3
Molecular Weight:183.21

Section 10 - Stability and Reactivity


Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: Not available.
Incompatibilities with Other Materials: Acids - acid chlorides - acid anhydrides - oxidizing agents - light.
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen gas.
Hazardous Polymerization: Has not been reported.

Section 11 - Toxicological Information


RTECS#:      
CAS# 51-43-4: DO2625000
LD50/LC50:
CAS# 51-43-4:
     Skin, rat: LD50 = 62 mg/kg;
.

Carcinogenicity:
CAS# 51-43-4: Not listed by ACGIH, IARC, NTP, or CA Prop 65.

Epidemiology: No information available.
Teratogenicity: No information available.
Reproductive Effects: No information available.
Mutagenicity: No information available.
Neurotoxicity: No information available.
Other Studies:

Section 12 - Ecological Information

No information available.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: CAS# 51-43-4: waste number P042.
RCRA U-Series: None listed.

Section 14 - Transport Information

US DOT Canada TDG
Shipping Name: Not regulated as a hazardous material No information available.
Hazard Class:
UN Number:
Packing Group:

Section 15 - Regulatory Information

US FEDERAL

TSCA
     CAS# 51-43-4 is listed on the TSCA inventory.
Health & Safety Reporting List
     None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
     None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
     None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
     None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
     CAS# 51-43-4: 1000 lb final RQ; 454 kg final RQ
SARA Section 302 Extremely Hazardous Substances
     None of the chemicals in this product have a TPQ.
SARA Codes
     CAS # 51-43-4: immediate, delayed.
Section 313      No chemicals are reportable under Section 313.
Clean Air Act:
     This material does not contain any hazardous air pollutants.
     This material does not contain any Class 1 Ozone depletors.
     This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
     None of the chemicals in this product are listed as Hazardous Substances under the CWA.
     None of the chemicals in this product are listed as Priority Pollutants under the CWA.
     None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
     None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
     CAS# 51-43-4 can be found on the following state right to know lists: New Jersey, Pennsylvania, Massachusetts.

California Prop 65

California No Significant Risk Level: None of the chemicals in this product are listed.

European/International Regulations

European Labeling in Accordance with EC Directives
Hazard Symbols:
     T
Risk Phrases:

     R 23/24/25 Toxic by inhalation, in contact with skin and if
     swallowed.
     R 33 Danger of cumulative effects.

Safety Phrases:

     S 23 Do not inhale gas/fumes/vapour/spray.
     S 24/25 Avoid contact with skin and eyes.

WGK (Water Danger/Protection)

     CAS# 51-43-4: 3
Canada - DSL/NDSL
     CAS# 51-43-4 is listed on Canada's DSL List.
Canada - WHMIS
     WHMIS: Not available.
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations.
Canadian Ingredient Disclosure List

Section 16 - Additional Information

MSDS Creation Date: 8/24/1997
Revision #4 Date: 3/25/2008

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.

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