Section 1 - Chemical Product and Company Identification |
MSDS Name: Lithium bis(trimethylsilyl)amide, 1.3M solution in THF
Catalog Numbers:
AC413315000
Synonyms:
1,1,1,3,3,3-Hexamethyldisilazane lithium salt.
Company Identification:
Acros Organics N.V.
One Reagent Lane
Fair Lawn, NJ 07410
For information in North America, call: 800-ACROS-01
For emergencies in the US, call CHEMTREC: 800-424-9300
Section 2 - Composition, Information on Ingredients
|
CAS# |
Chemical Name |
Percent |
EINECS/ELINCS |
109-99-9 |
Tetrahydrofuran |
78.29 | 203-726-8 |
4039-32-1 |
Lithium bis(trimethylsilyl)amide |
21.71 | 223-725-6 |
Section 3 - Hazards Identification
|
EMERGENCY OVERVIEW
Appearance: not available. Flash Point: -17 deg C.
Danger! Corrosive. Causes eye and skin burns.
Uninhibited material, or material from which the inhibitor has been
removed or reacted, may form explosive peroxides.
Flammable liquid and vapor. May cause severe respiratory
tract irritation with possible burns. May cause severe digestive
tract irritation with possible burns. May form explosive peroxides.
Air sensitive.
Target Organs: None.
Potential Health Effects
Eye:
Causes eye burns.
Skin:
Causes skin burns.
Ingestion:
May cause severe and permanent damage to the digestive tract. Causes
gastrointestinal tract burns.
Inhalation:
Causes chemical burns to the respiratory tract. Vapors may cause
dizziness or suffocation.
Chronic:
None
Section 4 - First Aid Measures
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Eyes:
Flush eyes with plenty of water for at least 15 minutes, occasionally
lifting the upper and lower eyelids. Get medical aid immediately. Do
NOT allow victim to rub eyes or keep eyes closed. Extensive irrigation
with water is required (at least 30 minutes).
Skin:
Get medical aid immediately. Immediately flush skin with plenty of
water for at least 15 minutes while removing contaminated clothing
and shoes. Wash clothing before reuse. Destroy contaminated shoes.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4
cupfuls of milk or water. Never give anything by mouth to an
unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh
air immediately. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Do NOT use mouth-to-mouth
resuscitation.
Notes to Physician:
Treat symptomatically and supportively.
Section 5 - Fire Fighting Measures
|
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. Vapors may form an explosive mixture with air.
During a fire, irritating and highly toxic gases may be generated by
thermal decomposition or combustion. Will burn if involved in a fire.
Use water spray to keep fire-exposed containers cool. Containers may
explode in the heat of a fire. Flammable liquid and vapor. May form
explosive peroxides. Vapors may be heavier than air. They can
spread along the ground and collect in low or confined areas.
Extinguishing Media:
For small fires, use dry chemical, carbon dioxide, water spray or
alcohol-resistant foam. For large fires, use water spray, fog, or
alcohol-resistant foam. Do NOT use water directly on fire. Use water
spray to cool fire-exposed containers. Water may be ineffective. Do
NOT use straight streams of water.
Flash Point: -17 deg C ( 1.40 deg F)
Autoignition Temperature: Not applicable.
Explosion Limits, Lower:N/A
Upper: N/A
NFPA Rating:
(estimated) Health: 3; Flammability: 4; Instability: 1
Section 6 - Accidental Release Measures
|
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container. Clean up spills immediately,
observing precautions in the Protective Equipment section. Remove all
sources of ignition. Use a spark-proof tool. Isolate area and deny
entry. Provide ventilation. Place under an inert atmosphere. A vapor
suppressing foam may be used to reduce vapors.
Section 7 - Handling and Storage
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Handling:
Remove contaminated clothing and wash before reuse. Use only in a
well-ventilated area. Ground and bond containers when transferring
material. Use spark-proof tools and explosion proof equipment. Do not
get in eyes, on skin, or on clothing. Empty containers retain product
residue, (liquid and/or vapor), and can be dangerous. Keep container
tightly closed. Keep away from heat, sparks and flame. Do not ingest
or inhale. If peroxide formation is suspected, do not open or move
container. Avoid contact with air and sunlight. Discard contaminated
shoes. Do not pressurize, cut, weld, braze, solder, drill, grind, or
expose empty containers to heat, sparks or open flames. Unused
chemicals should not be returned to the container. Do not distill
since this removes peroxide-inhibitors.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of
ignition. Do not store in direct sunlight. Keep container closed
when not in use. Store in a tightly closed container. Store in a
cool, dry, well-ventilated area away from incompatible substances.
Flammables-area. Regularly check inhibitor levels to maintain
peroxide levels below 1%. Do not break the seal on the container
until it is needed. Label the container with the date it was first
opened. Long-term storage is not recommended.
Section 8 - Exposure Controls, Personal Protection
|
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate general or
local exhaust ventilation to keep airborne concentrations below the
permissible exposure limits.
Exposure Limits
Chemical Name |
ACGIH |
NIOSH |
OSHA - Final PELs |
Tetrahydrofuran
|
50 ppm TWA; 100 ppm STEL; Skin - potential significant contribution to overall exposure by the cutaneous r oute
|
200 ppm TWA; 590 mg/m3 TWA 2000 ppm IDLH
|
200 ppm TWA; 590 mg/m3 TWA
|
Lithium bis(trimethylsilyl)amide
|
none listed
|
6 mg/m3 TWA (listed under Silica, amorphous).3000 mg/m3 IDLH (listed under Silica, amorphous).
|
none listed
|
OSHA Vacated PELs:
Tetrahydrofuran:
200 ppm TWA; 590 mg/m3 TWA
Lithium bis(trimethylsilyl)amide:
No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Wear a NIOSH/MSHA or European Standard EN 149
approved full-facepiece airline respirator in the
positive pressure mode with emergency escape
provisions.
Section 9 - Physical and Chemical Properties
|
Physical State: Liquid
Appearance: not available
Odor: none reported
pH: Not available.
Vapor Pressure: Not available.
Vapor Density: 5.8
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point:Not available.
Decomposition Temperature:Not available.
Solubility: reacts with water.
Specific Gravity/Density:.8150g/cm3
Molecular Formula:C6H18LiNSi2
Molecular Weight:167.2447
Section 10 - Stability and Reactivity
|
Chemical Stability:
Stable under normal temperatures and pressures. On long term
storage, substances with similar functional groups form explosive
peroxides. Explosive peroxides may form on concentration. Peroxides
can be detonated by friction, impact, or heating. Tends to form
explosive peroxides; especially when anhydrous. Peroxide formation
may occur in containers that have been opened and remain in storage.
Conditions to Avoid:
Incompatible materials, ignition sources, exposure to air, excess
heat, strong oxidants.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen, silicon
dioxide.
Hazardous Polymerization: Has not been reported.
Section 11 - Toxicological Information
|
RTECS#:
CAS# 109-99-9:
LU5950000
CAS# 4039-32-1
unlisted.
LD50/LC50:
CAS# 109-99-9: Inhalation, rat:
LC50 = 21000 ppm/3H; Oral, rat:
LD50 = 1650 mg/kg; .
CAS# 4039-32-1: .
Carcinogenicity:
CAS# 109-99-9:
- ACGIH:
A3 - Confirmed animal carcinogen with unknown relevance to humans
- California:
Not listed.
- NTP:
Not listed.
- IARC:
Not listed.
CAS# 4039-32-1:
Not listed by ACGIH, IARC, NTP, or CA Prop 65.
Epidemiology:
No information available.
Teratogenicity:
No information available.
Reproductive Effects:
No information available.
Mutagenicity:
No information available.
Neurotoxicity:
No information available.
Other Studies:
Section 12 - Ecological Information
|
Ecotoxicity:
No data available.
Cas# 109-00-0:LC50(96Hr.) Fathead Minnow = 2160 mg/L
Environmental:
Tetrahydrofuran is expected to biodegrade under aerobic conditions
but may be resistant to biodegradation in anaerobic environments.
Physical:
According to a model of gas/particle partitioning of semivolatile
organic compounds in the atmosphere, tetrahydrofuran, which has a
vapor pressure of 162 mm Hg at 25 deg C, determined from
experimentally-derived coefficients, will exist solely as a vapor in
the ambient atmosphere. Vapor-phase tetrahydrofuran is degraded in
the atmosphere by reaction with photochemically-produced hydroxyl
radicals and nitrate radicals; the half-lives for these reactions in
air are estimated to be about 1 day and 3 days, respectively.
Other:
No information available.
Section 13 - Disposal Considerations
|
Chemical waste generators must determine whether a discarded chemical is classified
as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3.
Additionally, waste generators must consult state and local hazardous waste regulations to
ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: CAS# 109-99-9: waste
number U213 (Ignitable waste).
Section 14 - Transport Information
|
|
US DOT |
Canada TDG |
Shipping Name: |
FLAMMABLE LIQUIDS, CORROSIVE, N.O.S. |
No information available. |
Hazard Class: |
3 |
|
UN Number: |
UN2924 |
|
Packing Group: |
II |
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Section 15 - Regulatory Information
|
US FEDERAL
TSCA
CAS# 109-99-9 is listed on the TSCA inventory.
CAS# 4039-32-1 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
CAS# 109-99-9: Testing required by manufacturers, processors; Test for Health Effects
Section 12b
CAS# 109-99-9: Section 4
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
CAS# 109-99-9: 1000 lb final RQ; 454 kg final RQ
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 109-99-9: immediate, fire, reactive.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants.
This material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product
are listed as Hazardous Substances under the CWA.
None of the chemicals in this
product are listed as Priority Pollutants under the CWA.
None of the chemicals in this
product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product
are considered highly hazardous by OSHA.
STATE
CAS# 109-99-9 can be found on the
following state right to know lists: California, New Jersey,
Pennsylvania, Minnesota, Massachusetts.
CAS# 4039-32-1 can be found on the
following state right to know lists: California, (listed as Silica,
amorphous), New Jersey, (listed as Silica, amorphous), Pennsylvania,
(listed as Silica, amorphous), Minnesota, (listed as Silica,
amorphous), Massachusetts, (listed as Silica, amorphous).
California Prop 65
California No Significant Risk Level:
None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: F C
Risk Phrases:
R 11 Highly flammable.
R 19 May form explosive peroxides.
R 34 Causes burns.
Safety Phrases:
S 16 Keep away from sources of ignition - No smoking.
S 29 Do not empty into drains.
S 33 Take precautionary measures against static discharges.
S 36/37/39 Wear suitable protective clothing, gloves and eye/face pr
otection.
S 9 Keep container in a well-ventilated place.
WGK (Water Danger/Protection)
CAS# 109-99-9: 1
CAS# 4039-32-1: No information available.
Canada - DSL/NDSL
CAS# 109-99-9 is listed on Canada's DSL List.
CAS# 4039-32-1 is listed on Canada's NDSL List.
Canada - WHMIS
This product has a WHMIS classification of B2, E.
This product has been classified in accordance with the hazard
criteria of the Controlled Products Regulations and the MSDS
contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
CAS# 109-99-9 is listed on the Canadian Ingredient Disclosure List.
CAS# 4039-32-1 (listed as Silica, amorphous) is listed on the Canadian Ingredient Disclosure List.
Section 16 - Additional Information
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MSDS Creation Date: 6/02/1999 Revision #4 Date: 10/03/2005
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no event shall Fisher be liable
for any claims, losses, or damages of any third party or for lost profits
or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if Fisher has been advised of
the possibility of such damages.
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