SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 08/JUN/2005
Date Updated: 22/NOV/2004
Version 1.4
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name FORMIC ACID, 96%, A.C.S. REAGENT
Product Number 251364
Company Sigma-Aldrich Pty. Ltd.
12 Anella Avenue
Castle Hill NSW 2154
Australia
Technical Phone # +61 2 9841 0555 (1800 800 097)
Fax +61 2 9841 0500 (1800 800 096)
Emergency Phone # +44 8701906777 (1800 448 465)
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
FORMIC ACID >=90% 64-18-6 200-579-1 607-001-00-0
Formula CH2O2
Molecular Weight 46.03 AMU
Synonyms Acide formique (French) * Acido formico
(Italian) * Ameisensaeure (German) * Aminic acid
* Formic acid (ACGIH:OSHA) * Formylic acid *
Hydrogen carboxylic acid * Kwas metaniowy
(Polish) * Kyselina mravenci (Czech) * Methanoic
acid * Mierenzuur (Dutch) * RCRA waste number
U123
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Causes severe burns.
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER SKIN CONTACT
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.
AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician. Do not induce vomiting.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Carbon dioxide, dry chemical powder, or appropriate
foam.
SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.
Combustible liquid.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Cover with dry lime or soda ash, pick up, keep in a closed
container, and hold for waste disposal. Ventilate area and wash
spill site after material pickup is complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe vapor. Do not get
in eyes, on skin, on clothing. Avoid prolonged or repeated
exposure.
STORAGE
Conditions of Storage: Keep tightly closed. Keep away from heat
and open flame.
SPECIAL REQUIREMENTS: Vent periodically. May develop pressure.
Open carefully. Hygroscopic.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Safety shower and eye bath. Use only in a chemical fume hood.
GENERAL HYGIENE MEASURES
Wash contaminated clothing before reuse. Discard contaminated
shoes. Wash thoroughly after handling.
EXPOSURE LIMITS
Country Source Type Value
Poland NDS 5 MG/M3
Poland NDSCh 15 MG/M3
Poland NDSP -
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EXPOSURE LIMITS - DENMARK
Source Type Value
OEL TWA 1 mg/m3
5 ppm
EXPOSURE LIMITS - GERMANY
Source Type Value
TRGS 900 OEL 9 mg/m3
5 ppm
Remarks: =1=
EXPOSURE LIMITS - NORWAY
Source Type Value
OEL 9 mg/m3
5 ppm
EXPOSURE LIMITS - SWEDEN
Source Type Value
LLV (Level5 mg/m3
3 ppm
EXPOSURE LIMITS - SWITZERLAND
Source Type Value
OEL OEL 9.5 mg/m3
5 ppm
Remarks: C*
EXPOSURE LIMITS - UNITED KINGDOM
Source Type Value
OEL OEL 9.6 mg/m3
5 ppm
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
Special Protective Measures: Faceshield (8-inch minimum).
9 - Physical and Chemical Properties
Appearance Physical State: Liquid
Color: Colorless
Property Value At Temperature or Pressure
pH 2.2 20 掳C Concentration: 2.2
g/l
BP/BP Range 100.8 掳C 760 mmHg
MP/MP Range 8.5 掳C
Flammability N/A
Autoignition Temp 540 掳C
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits Lower: 18 %
Upper: 57 %
Vapor Pressure 44.8 mmHg 20 掳C
SG/Density 1.2 g/cm3
Partition Coefficient Log Kow: -0.54
Viscosity 0.002 Pas 20 掳C
Vapor Density 1.6 g/l
Saturated Vapor Conc. N/A
Evaporation Rate N/A
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Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension 38 mN/m 15 掳C
Conductivity N/A
Miscellaneous Data N/A
Solubility Solubility in Water:Miscible.
Other Solvents: VERYSOLUBLE IN ACETONE
MISCIBLE WITH ALCOHOL, ETHE
10 - Stability and Reactivity
STABILITY
Stable: Stable.
Conditions to Avoid: Moisture.
Materials to Avoid: Strong oxidizing agents, Strong bases, Finely
powdered metals.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
RTECS NUMBER: LQ4900000
ACUTE TOXICITY
LDLO
Oral
Woman
2.44 mg/kg
Remarks: Vascular:Shock. Blood:Other hemolysis with or withot
anemia. Nutritional and Gross Metabolic:Changes in:Metabolic
acidosis.
LD50
Oral
Rat
1100 mg/kg
Remarks: Behavioral:Somnolence (general depressed activity).
Lungs, Thorax, or Respiration:Dyspnea.
LC50
Inhalation
Rat
15,000 mg/m3
15M
Remarks: Behavioral:Somnolence (general depressed activity).
Lungs, Thorax, or Respiration:Dyspnea.
LD50
Oral
Mouse
700 mg/kg
Remarks: Behavioral:Somnolence (general depressed activity).
Lungs, Thorax, or Respiration:Dyspnea.
LC50
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Inhalation
Mouse
6,200 mg/m3
15M
Remarks: Behavioral:Somnolence (general depressed activity).
Lungs, Thorax, or Respiration:Dyspnea.
LD50
Intraperitoneal
Mouse
940 MG/KG
LD50
Intravenous
Mouse
145 MG/KG
LD50
Oral
Dog
4000 mg/kg
IRRITATION DATA
Skin
Rabbit
Remarks: Severe irritation effect
Skin
Rabbit
610 mg
Remarks: Open irritation test
Eyes
Rabbit
122 mg
Remarks: Severe irritation effect
SENSITIZATION
Sensitization: Prolonged or repeated exposure may cause allergic
reactions in certain sensitive individuals.
SIGNS AND SYMPTOMS OF EXPOSURE
Material is extremely destructive to tissue of the mucous
membranes and upper respiratory tract, eyes, and skin.
Inhalation may result in spasm, inflammation and edema of the
larynxand bronchi, chemical pneumonitis, and pulmonary edema.
Symptoms of exposure may include burning sensation, coughing,
wheezing, laryngitis, shortness of breath, headache, nausea, and
vomiting.
ROUTE OF EXPOSURE
Skin Contact: Causes burns.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: Causes burns.
Inhalation: Material is extremely destructive to the tissue of
the mucous membranes and upper respiratory tract. May be harmful
if inhaled.
Ingestion: May be harmful if swallowed.
TARGET ORGAN INFORMATION
Kidneys. Liver. Central nervous system. Blood.
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CHRONIC EXPOSURE - MUTAGEN
Human
10 MMOL/L
Cell Type: lymphocyte
Sister chromatid exchange
Hamster
10 MMOL/L
Cell Type: ovary
Cytogenetic analysis
12 - Ecological Information
ELIMINATION
Elimination: > 90 %
ECOTOXICOLOGICAL EFFECTS
Test Type: EC50 Algae
Time: 72 h
Value: 26.9 mg/l
Test Type: EC50 Daphnia
Species: Daphnia magna
Time: 48 h
Value: 34.2 mg/l
Test Type: LC50 Fish
Species: Leuciscus idus
Time: 96 h
Value: 46 - 100 mg/l
ADDITIONAL ECOLOGICAL INFORMATION
BOD5: 8.6 %
COD: 34.8 %
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Observe all federal, state, and local
environmental regulations. This combustible material may be burned
in a chemical incinerator equipped with an afterburner and
scrubber.
14 - Transport Information
RID/ADR
UN#: 1779
Class: 8
PG: II
Proper Shipping Name: Formic acid
IMDG
UN#: 1779
Class: 8
PG: II
Proper Shipping Name: Formic acid
Marine Pollutant: No
Severe Marine Pollutant: No
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IATA
UN#: 1779
Class: 8
PG: II
Proper Shipping Name: Formic acid
Inhalation Packing Group I: No
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
ANNEX I INDEX NUMBER: 607-001-00-0
NOTA: B
INDICATION OF DANGER: C
Corrosive.
R-PHRASES: 35
Causes severe burns.
S-PHRASES: 23 26 45
Do not breathe vapor. In case of contact with eyes, rinse
immediately with plenty of water and seek medical advice. In
case of accident or if you feel unwell, seek medical advice
immediately (show the label where possible).
COUNTRY SPECIFIC INFORMATION
Germany
WGK: 1
SWITZERLAND
SWISS POISON CLASS: 3
NORWAY
Declaration Number: 67085
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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