SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 15/MAR/2005
Date Updated: 17/MAR/2004
Version 1.6
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name HEXADECYLTRIMETHYLAMMONIUM BROMIDE,
SIGMAULTRA
Product Number H9151
Company Sigma-Aldrich Pty, Ltd
Unit 2, 14 Anella Avenue
Castle Hill NSW 1765
Australia
Technical Phone # +61 2 9841 0555
Fax +61 2 9841 0500
Emergency Phone # +61 2 9841 0566
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
CETYLTRIMETHYL AMMONIUM BROMIDE 57-09-0 200-311-3 None
Formula C19H42N.Br
Molecular Weight 364.46 AMU
Synonyms Acetoquat CTAB * Bromat * Centimide * Cetarol *
Cetrimonium bromide * Cetyltrimethylammonium
bromide * N-Cetyltrimethylammonium bromide *
Cirrasol-OD * CTAB * Cycloton V *
1-Hexadecanaminium, N,N,N-trimethyl-, bromide *
Hexadecyltrimethylammonium bromide *
N-Hexadecyl-N,N,N-trimethylammonium bromide *
(1-Hexadecyl)trimethylammonium bromide *
Lauroseptol * Lissolamine * Lissolamine A *
Micol * Palmityltrimethyl ammonium bromide *
Pollacid * Quamonium * Softex KW *
Trimethylcetylammonium bromide *
N,N,N-Trimethyl-1-hexadecanaminium bromide *
Trimethylhexadecylammonium bromide
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Harmful if swallowed. Irritating to respiratory system and skin.
Risk of serious damage to eyes. Very toxic to aquatic organisms.
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER SKIN CONTACT
In case of contact, immediately wash skin with soap and copious
amounts of water.
AFTER EYE CONTACT
In case of contact, immediately flush eyes with copious amounts
of water for at least 15 minutes.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.
SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear respirator, chemical safety goggles, rubber boots, and
heavy rubber gloves.
METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Avoid
raising dust. Ventilate area and wash spill site after material
pickup is complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe dust. Avoid contact
with eyes, skin, and clothing. Avoid prolonged or repeated
exposure.
STORAGE
Conditions of Storage: Keep tightly closed.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Safety shower and eye bath. Mechanical exhaust required.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling.
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
9 - Physical and Chemical Properties
Appearance Physical State: Solid
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Property Value At Temperature or Pressure
pH 5-7
BP/BP Range N/A
MP/MP Range 230 掳C
Flash Point 244 掳C Method: closed cup
Flammability N/A
Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure N/A
SG/Density N/A
Partition Coefficient Log Kow: 3.18
Viscosity N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility Solubility in Water:0.1 M in H2O, 20掳C
complete, colorless
10 - Stability and Reactivity
STABILITY
Stable: Stable.
Materials to Avoid: Strong oxidizing agents.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide,
Nitrogen oxides, Hydrogen bromide gas.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
RTECS NUMBER: BQ7875000
ACUTE TOXICITY
LD50
Oral
Rat
410 mg/kg
LD50
Intravenous
Rat
44 MG/KG
Remarks: Lungs, Thorax, or Respiration:Other changes.
LD50
Intraperitoneal
Mouse
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106 MG/KG
Remarks: Behavioral:Convulsions or effect on seizure threshold.
Lungs, Thorax, or Respiration:Respiratory depression.
LD50
Intravenous
Mouse
32 MG/KG
Remarks: Lungs, Thorax, or Respiration:Other changes.
LD50
Intraperitoneal
Rabbit
125 MG/KG
LD50
Subcutaneous
Rabbit
125 MG/KG
LD50
Subcutaneous
Guinea pig
100 MG/KG
IRRITATION DATA
Skin
Mouse
50 mg
1H
Remarks: Open irritation test
Eyes
Rabbit
450 mg
Remarks: Severe irritation effect
SIGNS AND SYMPTOMS OF EXPOSURE
To the best of our knowledge, the chemical, physical, and
toxicological properties have not been thoroughly investigated.
ROUTE OF EXPOSURE
Skin Contact: Causes skin irritation.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: Causes severe eye irritation.
Inhalation: Material is irritating to mucous membranes and upper
respiratory tract. May be harmful if inhaled.
Ingestion: Harmful if swallowed.
CHRONIC EXPOSURE - TERATOGEN
Species: Mouse
Dose: 10500 UG/KG
Route of Application: Intraperitoneal
Exposure Time: (8D PREG)
Result: Specific Developmental Abnormalities: Musculoskeletal
system.
Species: Mouse
Dose: 10500 UG/KG
Route of Application: Intraperitoneal
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Exposure Time: (10D PREG)
Result: Specific Developmental Abnormalities: Craniofacial
(including nose and tongue).
Species: Mouse
Dose: 35 MG/KG
Route of Application: Intraperitoneal
Exposure Time: (12D PREG)
Result: Effects on Embryo or Fetus: Fetotoxicity (except death,
e.g., stunted fetus).
CHRONIC EXPOSURE - REPRODUCTIVE HAZARD
Species: Mouse
Dose: 35 MG/KG
Route of Application: Intraperitoneal
Exposure Time: (8D PREG)
Result: Effects on Fertility: Post-implantation mortality (e.g.,
dead and/or resorbed implants per total number of implants).
12 - Ecological Information
ELIMINATION
Elimination: 100 %
ECOTOXICOLOGICAL EFFECTS
Test Type: EC50 Daphnia
Species: Daphnia magna
Time: 48 h
Value: 0.03 mg/l
Test Type: LC50 Fish
Species: Brachydanio rerio
Time: 96 h
Value: 0.3 mg/l
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
environmental regulations.
14 - Transport Information
RID/ADR
UN#: 3077
Class: 9
PG: III
Proper Shipping Name: Environmentally hazardous
substance, solid, n.o.s
IMDG
UN#: 3077
Class: 9
PG: III
Proper Shipping Name: Environmentally hazardous
substance, solid, n.o.s
Marine Pollutant: No
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Severe Marine Pollutant: Yes
Technical Name: Required
IATA
UN#: 3077
Class: 9
PG: III
Proper Shipping Name: Environmentally hazardous
substance, solid, n.o.s
Inhalation Packing Group I: No
Technical Name: Required
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
INDICATION OF DANGER: Xn N
Harmful. Dangerous for the environment.
R-PHRASES: 22 37/38 41 50
Harmful if swallowed. Irritating to respiratory system and
skin. Risk of serious damage to eyes. Very toxic to aquatic
organisms.
S-PHRASES: 26 36 60 61
In case of contact with eyes, rinse immediately with plenty of
water and seek medical advice. Wear suitable protective
clothing. This material and its container must be disposed of
as hazardous waste. Avoid release to the environment. Refer to
special instructions/safety data sheets.
COUNTRY SPECIFIC INFORMATION
Germany
WGK: 3
SWITZERLAND
SWISS POISON CLASS: 3
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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