SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 31/MAY/2005
Date Updated: 16/MAY/2005
Version 1.2
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name TETRABUTYLPHOSPHONIUM BROMIDE, 98%
Product Number 189138
Company Sigma-Aldrich Pty, Ltd
Unit 2, 14 Anella Avenue
Castle Hill NSW 1765
Australia
Technical Phone # +61 2 9841 0555
Fax +61 2 9841 0500
Emergency Phone # +61 2 9841 0566
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
TETRABUTYLPHOSPHONIUM BROMIDE 3115-68-2 221-487-8 None
Formula C16H36BrP
Molecular Weight 339.35 AMU
Synonyms PX 4B * Tetra-N-butylphosphonium bromide
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Harmful in contact with skin and if swallowed. Irritating to eyes,
respiratory system and skin.
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER SKIN CONTACT
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.
AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician immediately.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.
SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Avoid
raising dust. Ventilate area and wash spill site after material
pickup is complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe dust. Do not get in
eyes, on skin, on clothing. Avoid prolonged or repeated exposure.
STORAGE
Conditions of Storage: Keep tightly closed.
SPECIAL REQUIREMENTS: Hygroscopic.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Use only in a chemical fume hood. Safety shower and eye bath.
GENERAL HYGIENE MEASURES
Wash contaminated clothing before reuse. Wash thoroughly after
handling.
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
9 - Physical and Chemical Properties
Appearance Color: White
Form: Fine crystals
Property Value At Temperature or Pressure
pH N/A
BP/BP Range N/A
MP/MP Range 102 掳C
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Flash Point 290 掳C Method: closed cup
Flammability N/A
Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure N/A
SG/Density N/A
Partition Coefficient N/A
Viscosity N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility N/A
10 - Stability and Reactivity
STABILITY
Stable: Stable.
Materials to Avoid: Strong oxidizing agents.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide,
Hydrogen bromide gas, Thermal decomposition may produce toxic
fumes of phosphorus oxides and/or phosphine.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
RTECS NUMBER: TA2417000
ACUTE TOXICITY
LD50
Skin
Rabbit
*
LD50
Oral
Rat
420 mg/kg
Remarks: Gastrointestinal:Hypermotility, diarrhea. Lungs,
Thorax, or Respiration:Other changes. Liver:Other changes.
LC50
Inhalation
Rat
> 3 mg/m3
1H
LD50
Intravenous
Mouse
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56 MG/KG
LD50
Skin
Rabbit
197 mg/kg
Remarks: Behavioral:Somnolence (general depressed activity).
Behavioral:Convulsions or effect on seizure threshold. Lungs,
Thorax, or Respiration:Dyspnea.
IRRITATION DATA
Skin
Rabbit
500 mg
Remarks: Severe irritation effect
Eyes
Rabbit
0.1 ml
24H
Remarks: Severe irritation effect
SIGNS AND SYMPTOMS OF EXPOSURE
To the best of our knowledge, the chemical, physical, and
toxicological properties have not been thoroughly investigated.
ROUTE OF EXPOSURE
Skin Contact: Causes skin irritation.
Skin Absorption: Harmful if absorbed through skin.
Eye Contact: Causes eye irritation.
Inhalation: May be harmful if inhaled. Material is irritating to
mucous membranes and upper respiratory tract.
Ingestion: Harmful if swallowed.
12 - Ecological Information
N/A
ELIMINATION
Elimination: 10 - 30 %
ECOTOXICOLOGICAL EFFECTS
Test Type: LC50 Fish
Species: Leuciscus idus
Time: 48 h
Value: 100 - 1,000 mg/l
Test Type: LC50 Bacteria
Time: 3 h
Value: > 1,000 mg/l
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
environmental regulations.
14 - Transport Information
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RID/ADR
UN#: 3464
Class: 6.1
PG: III
Proper Shipping Name: Organophosphorus compound,
toxic, solid, n.o.s.
IMDG
UN#: 3464
Class: 6.1
PG: III
Proper Shipping Name: Organophosphorus compound,
toxic, solid, n.o.s.
Marine Pollutant: No
Severe Marine Pollutant: No
Technical Name: Required
IATA
UN#: 3464
Class: 6.1
PG: III
Proper Shipping Name: Organophosphorus compound,
toxic, solid, n.o.s.
Inhalation Packing Group I: No
Technical Name: Required
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
INDICATION OF DANGER: Xn
Harmful.
R-PHRASES: 36/37/38 21/22
Irritating to eyes, respiratory system and skin. Harmful in
contact with skin and if swallowed.
S-PHRASES: 26 37/39
In case of contact with eyes, rinse immediately with plenty of
water and seek medical advice. Wear suitable gloves and
eye/face protection.
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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