MATERIAL SAFETY DATA SHEET SSPE BUFFER DRY MIX
PRODUCT CODE NUMBER(S): 8471-5
PRODUCT IDENTIFICATION Reactivity: Avoid excessive heat, ignition sources, genera-
tion of dust, all incompatible materials.
Chemical Name and Synonyms: SSPE Buffer dry-mix Hazardous Decomposition Products: Thermal decompo-
Chemical Family: Mixture of salts sition may release caustic fumes of sodium, phosphrous and
COx
Chemical Formula: Na2HPO4.7H2O, EDTA and NaCl
Product Use: Laboratory reagent
FIRE AND EXPLOSION DATA
Manufacturer's Name and Address:
Flammability: Negligible fire hazard when exposed to heat
Caledon Laboratories Ltd.,
or flame. As with most organic compounds, fine dust dis-
40 Armstrong Avenue,
persed in air in the presence of an ignition source is a
Georgetown, Ontario L7G 4R9
potential dust explosion hazard.
Telephone No: (905) 877-0101
Extinguishing Media: Use extinguishing media
Fax No: (905) 877-6666 pappropriate to the surrounding fire. Water spray can be
used to cool containers, flush chemical away from fire. Fight
Emergency Telephone No: CANUTEC (613) 996-6666
fire from upwind, from a safe distance. Firefighters must
HAZARDOUS INGREDIENTS OF MATERIALS wear protective equipment and clothing sufficient to prevent
inhalation of mist or fumes, and contact with skin and eyes.
Ingredients % TLV Units CAS No. Flash Point (Method Used): Not applicable. Does not
form vapour
Sodium phosphate, N/A Not established 7782-85-6
Autoignition Temperature: Not available
dibasic, heptahydrate
Upper Flammable Limit (% by volume): Not available
Sodium chloride N/A Not established 7647-14-5
Lower Flammable Limit (% by volume): Not available
Ethylenediamine Hazardous Combustion Products: Toxic, irritating fumes
tetraacetic acid N/A Not established 6381-92-6
Sensitivity to Impact: None identified
PHYSICAL DATA Sensitivity to Static discharge: As with most organic pow-
ders, mixtures of dust with air may be sensitive under
Physical State: Solid certain conditions, when ignited by an electrostatic or other
high-voltage spark, or other ignition source.
Odour and Appearance: Odorless, colorless to white crys-
tals or free-flowing granules.
TOXICOLOGICAL PROPERTIES AND HEALTH DATA
Odour Threshold (ppm): Not applicable
Vapour Pressure (mm Hg): Not available Toxicological Data:
Vapour Density (Air = 1): Not available
LD50: (oral, rat) 3 g/kg (NaCl); (oral, rat) 12,930 mg/kg
Evaporation Rate: Not available (Na2HPO4.7H2O)
Boiling Point (degrees C): Decomposes LC50: Not available
Melting Point (degrees C): Not available Irritation: (eye, rabbit) 500 mg/24h, mild;
pH: Not available (skin, rabbit) 500 mg/24h, mild (Na2HPO4.7H2O)
Specific Gravity: Not available
Effects of Acute Exposure to Product:
Coefficient of Water/Oil distribution: Not available
Inhaled: Essentially non-toxic. May cause irritation to nose
SHIPPING DESCRIPTION throat and upper respiratory tract.
In contact with skin: May cause mechanical irritation.
UN: Not regulated
In contact with eyes: May cause mild irritation with tem-
T.D.G. Class: Not regulated
porary redness, itching, tearing, pain.
Pkg. Group: Not regulated
Ingested: Essentially non-toxic. May cause mild gastroin-
testinal irritation. Large doses may cause nausea and
REACTIVITY DATA vomiting and exert a mild diuretic or laxative effect producing
diarrhea. In addition, severe overdosages of sodium salts
Chemical Stability: Stable under normal temperatures and
may cause hypernoia and convulsing.
pressures
Incompatibility with other substances: May react vigor-
Effects of Chronic Exposure to Product:
ously with bases, oxidizing agents, acids. Attacks copper,
brass, aluminum, but not steel or iron. Aluminum reacts with Sodium chloride presents no serious health effects in normal
aqueous solutions of EDTA to release hydrogen. industrial usage. However, sodium chloride is linked to
heart and blood pressure problems through dietary intake.
SSPE BUFFER DRY MIX
MSDS
CODE: 8471-5
Persons afflicted with blood pressure or heart problems holding eyelids open while flushing. Get medical advice if
irritation persists.
may be sensitized to workplace exposures.
Skin: Brush or wipe off dry material. Flush skin thoroughly
Dermatitis may develop from repeated or prolonged skin ex-
with running water until no trace of chemical remains. Get
posure to sodium phosphate. Long term ingestion of >1%
medical attention if irritation develops.
sodium phosphate in diet caused kidney damage in rats; no
Inhalation: Remove to fresh air. Give oxygen and get
effects were observed after administration of 0.5% of diet
medical attention for breathing difficulty.
over a three-year period.
Ingestion: If victim is alert and not convulsing, give 2 to 4
Carcinogenicity: None glasses of water to dilute material. If vomiting occurs, rinse
Teratogenicity: No information available mouth and give more water to drink. If victim feels unwell,
or if a large amount has been ingested, get medical atten-
Reproductive Effects: No information available
tion.
Mutagenicity: No information available
Synergistic Products: None known REFERENCES USED
PREVENTIVE MEASURES CINFO disc: Cheminfo
Budavari: The Merck Index, 12th ed., 1997
Engineering Controls: Local exhaust ventilation.
Royal Society of Chemistry: Chemical Safety Data Sheets,
Respiratory Protection: Dust/mist mask. For conditions
Vol. 2, 1989
where dust or mist is present, to the maximum use specified
Sax, Lewis: Hawley's Condensed Chemical Dictionary, 11th
by the respirator supplier, NIOSH/OSHA approved half- face
ed., 1987
high-efficiency dust/mist filter respirator, or NIOSH/OSHA
approved full face-piece high-efficiency dust/mist filter respi- Suppliers' Material Safety Data Sheets
rator. Higher or unknown concentrations, or for fire or spill
conditions, self-contained breathing apparatus, or full ADDITIONAL INFORMATION
face-piece, positive-pressure supplied-air respirator.
Eye Protection: Chemical safety glasses. Do not wear Date Issued: May 6, 1999
contact lenses when working with chemicals. Revision: May 2008
Skin Protection: Wear protective gloves and clean MSDS: 8471-5
body-covering clothing, long-sleeved shirt, trousers, apron
Proposed WHMIS Designation: Not controlled. Not re-
or lab coat.
quired to be updated every three years (WHMIS 1992, B-40,
Other Personal Protective Equipment: Safety shower
Section 29,2)
and eye-wash fountain in work area.
Leak and Spill Procedure: Ventilate area. Cleanup per-
Prepared by: Caledon Laboratories Ltd. (905) 877-0101
sonnel should be thoroughly trained in the hazards of this
Caledon Laboratories Ltd. believes the information contained
material and should wear protective equipment and clothing
herein is reliable and accurate. Caledon makes no warranty
sufficient to prevent inhalation of dust or fumes, and contact
with respect thereto and expressly disclaims all liability for reli-
with skin and eyes. Prevent from entering sewers or water-
ance thereon. Such information is solely for your consider-
ways. Wet if necessary to control dust. Collect in a manner
that does not raise dust, and transfer carefully into labelled, ation, investigation, and verification.
covered container(s) for removal by disposal company.
Wash site of spillage thoroughly with water and detergent.
Waste Disposal: Follow all federal, provincial and local
regulations for disposal.
Handling Procedures and Equipment: COMBUSTIBLE
DUST. Workers using this chemical must be properly
trained in its hazards and its safe use, and must wear appro-
priate protective equipment and clothing. Avoid generating
dust. If there is dust, keep away from heat, sparks, and all
sources of ignition; avoid the accumulation of static charge,
use anti-sparking tools and ground and bond equipment and
containers. Use the smallest amount possible for the pur-
pose, in a designated area with adequate ventilation. Use
good housekeeping to prevent accumulations of dust. Avoid
contact with skin and eyes. Avoid inhalation. Wash thor-
oughly after handling.
Storage Requirements: Store in suitable, labelled contain-
ers, in a cool, dry, well-ventilated area, out of direct sunlight.
Store away from incompatible materials. Keep containers
tightly closed when not in use and when empty. Protect
from damage, and inspect frequently for signs of leaking.
FIRST AID MEASURES
Specific Measures:
Eyes: Flush eyes thoroughly with running water for five to
ten (5-10) minutes, or until no trace of chemical remains,
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