MATERIAL SAFETY DATA SHEET PHOSPHATE BUFFERED SALINE DRY-PACK
PRODUCT CODE NUMBER(S): 5840-5
PRODUCT IDENTIFICATION with strong acids, and may be mildly corrosive to steel and
aluminum.
Chemical Name and Synonyms: Phosphate buffered sa- Reactivity: Avoid excessive heat, ignition sources, genera-
line, dry-pack tion of dust, all incompatible materials.
Chemical Family: Mixture Hazardous Decomposition Products: Emits irritating
Chemical Formula: NaCl, KCl, and Na2HPO4.7H2O vapour at high temperatures.
Product Use: Laboratory reagent
FIRE AND EXPLOSION DATA
Manufacturer's Name and Address:
Caledon Laboratories Ltd. Flammability: Negligible fire hazard when exposed to heat
40 Armstrong Avenue or flame. As with most organic compounds, fine dust dis-
persed in air in the presence of an ignition source is a
Georgetown, Ontario L7G 4R9
potential dust explosion hazard.
Telephone No: (905) 877-0101
Extinguishing Media: Use extinguishing media appropri-
Fax No: (905) 877-6666
ate to the surrounding fire. Water in flooding amounts can
Emergency Telephone No: CANUTEC (613) 996-6666 be used to cool containers, prevent dust formation, flush
chemcial away from fire. Fight fire from upwind, from a safe
HAZARDOUS INGREDIENTS OF MATERIALS distance. Firefighters should wear protective equipment and
clothing sufficient to prevent inhalation of dust or fumes and
Ingredients % TLV Units CAS No. contact with skin and eyes.
Flash Point (Method Used): Not applicable
Sodium chloride 80-90 Not established 7647-14-5
Autoignition Temperature: Not applicable
Sodium phosphate, 12-15 Not established 7782-85-6
Upper Flammable Limit (% by volume): Not applicable
dibasic, heptahydrate
Lower Flammable Limit (% by volume): Not applicable
Potassium chloride 1-3 Not established 7447-40-7
Hazardous Combustion Products: Irritating vapours
PHYSICAL DATA Sensitivity to Impact: None
Sensitivity to Static discharge: Mixtures of dust with air
Physical State: Solid
may be sensitive under certain conditions, when ignited by
Odour and Appearance: White or off-white crystals or an electrostatic or other high-voltage spark, or other ignition
powder; odourless source.
Odour Threshold (ppm): Not applicable
TOXICOLOGICAL PROPERTIES AND HEALTH DATA
Vapour Pressure (mm Hg): Not available
Vapour Density (Air = 1): Not available
Toxicological Data:
Evaporation Rate: Not available
LD50: (oral, rat) 3 g/kg (NaCl); (oral, rat) 2,600 mg/kg (Kcl);
Boiling Point (degrees C): Not available
(oral, rat) 12,930 mg/kg (Na2HPO4.7H2O)
Melting Point (degrees C): Not available
LC50: Not available
pH: Not available
Specific Gravity: Not available Effects of Acute Exposure to Product:
Coefficient of Water/Oil distribution: Not available
Inhaled: Essentially non-toxic. May cause mild irritation to
nose throat and upper rMay cause mechanical irritation.
SHIPPING DESCRIPTION In contact with eyes: May cause mechanical irritation.
UN: Not regulated Ingested: Essentially non-toxic. Massive overdosage may
cause diarrhea, nausea and vomiting, hypernoea and con-
T.D.G. Class: Not regulated
vulsions
Pkg. Group: Not regulated
Other Health Effects: Sodium chloride presents no serious
health effects in normal industrial usage. However, sodium
REACTIVITY DATA chloride is linked to heart and blood pressure problems
through dietary intake. Persons afflicted with blood pres-
Chemical Stability: Stable under normal temperatures and
sure or heart problems may be sensitized to workplace
pressures
exposures. Improper use of salt tablets may cause irritation
Incompatibility with other substances: Sodium chloride
of the stomach. Sodium phosphate is not considered toxic,
is corrosive to steel and iron. Potassium chloride is incom-
but ingestion of large amounts may cause diarrhea, nausea,
patible with strong oxidizing agents, strong acids, lithium,
vomiting and cramps. Large oral doses of potassium chlo-
bromine trifluoride. Sodium phosphate may react violently
ride may cause diarrhea, nausea and vomiting, altered blood
picture, circulatory problems, hypernoea and convulsions
PHOSPHATE BUFFERED SALINE
MSDS DRY-PACK
CODE: 5840-5
FIRST AID MEASURES
Effects of Chronic Exposure to Product:
Dermatitis may develop from repeated or prolonged skin ex- Specific Measures:
posure to sodium phosphate. Long term ingestion of >1%
Eyes: Flush eyes thoroughly with running water for five to
(sodium phosphate) of diet caused kidney damage in rats;
ten (5-10) minutes, or until no trace of chemical remains,
no effects were observed after administration of 0.5% of diet
holding eyelids open while flushing. Get medical advice if ir-
over a three-year period.
ritation persists.
Carcinogenicity: Not considered carcinogenic
Skin: Brush or wipe off dry material. Flush skin thoroughly
Teratogenicity: No known effects with running water until no trace of chemical remains. Get
Reproductive Effects: No known effects medical attention if irritation develops.
Inhalation: Remove to fresh air. Give oxygen and get
Mutagenicity: No known effects
medical attention for breathing difficulty.
Synergistic Products: None known
Ingestion: If victim is alert and not convulsing, give 2 to 4
glasses of water to dilute material. If vomiting occurs, rinse
PREVENTIVE MEASURES
mouth and give more water to drink. If victim feels unwell,
Engineering Controls: Not required with normal use or if a large amount has been ingested, get medical atten-
tion.
Respiratory Protection: Dust/mist mask. For conditions
where dust or mist is present, to the maximum use specified
REFERENCES USED
by the respirator supplier, NIOSH/OSHA approved half- face
high-efficiency dust/mist filter respirator, or NIOSH/OSHA
CINFO disc: Cheminfo
approved full face-piece high-efficiency dust/mist filter respi-
Budavari: The Merck Index, 12th ed., 1997
rator. Higher or unknown concentrations, or for fire or spill
conditions, self-contained breathing apparatus, or full Royal Society of Chemistry: Chemical Safety Data Sheets,
face-piece, positive-pressure supplied-air respirator. Vol. 2, 1989
Eye Protection: Chemical safety glasses. Do not wear Sax, Lewis: Hawley's Condensed Chemical Dictionary, 11th
contact lenses when working with chemicals. ed., 1987
Skin Protection: Wear protective gloves and clean Suppliers' Material Safety Data Sheets
body-covering clothing sufficient to limit contact.
Other Personal Protective Equipment: Safety shower
ADDITIONAL INFORMATION
and eye-wash fountain in work area.
Leak and Spill Procedure: Ventilate area. If dust is pres- Date Issued: May 16, 1999
ent, eliminate all sources of ignition and all combustible Revision: May 2008
materials. Cleanup personnel must be thoroughly trained in
MSDS: 5840-5
the handling of hazardous materials and must wear protec-
WHMIS Designation: Not a controlled product. Not re-
tive equipment and clothing sufficient to prevent inhalation of
quired to be updated every three years (WHMIS 1992, B-40,
mist or fumes, and contact with skin and eyes. Prevent from
Section 29,2)
entering sewers or waterways. Mix with inert material and
collect in a manner that does not raise dust. Wet if neces-
sary. Contaminated absorbent may pose the same hazards Prepared by: Caledon Laboratories Ltd. (905) 877-0101
as the chemical; treat with caution. Wash site of spillage Caledon Laboratories Ltd. believes the information contained
thoroughly with water and detergent. herein is reliable and accurate. Caledon makes no warranty
Waste Disposal: Follow all federal, provincial and local with respect thereto and expressly disclaims all liability for reli-
regulations for disposal. ance thereon. Such information is solely for your consider-
Handling Procedures and Equipment: COMBUSTIBLE ation, investigation, and verification.
DUST. Workers using this chemical must be properly
trained in its hazards and its safe use, and must wear appro-
priate protective equipment and clothing. Avoid generating
dust. If there is dust, keep away from heat, sparks, and all
sources of ignition; avoid the accumulation of static charge,
use anti-sparking tools and ground and bond equipment and
containers. Use the smallest amount possible for the pur-
pose, in a designated area with adequate ventilation. Use
good housekeeping to prevent accumulations of dust. Avoid
contact with skin and eyes. Avoid inhalation. Wash thor-
oughly after handling. Empty containers may contain
hazardous residues; treat with caution.
Storage Requirements: Store in suitable, labelled contain-
ers, in a cool, dry, well-ventilated area, out of direct sunlight.
Keep containers tightly closed when not in use and when
empty. Protect from damage. Store away from incompatible
materials.
|