SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 02/JUN/2005
Date Updated: 20/MAY/2004
Version 1.2
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name TRIBUTYLTIN CHLORIDE, 96%
Product Number T50202
Company Sigma-Aldrich Pty, Ltd
Unit 2, 14 Anella Avenue
Castle Hill NSW 1765
Australia
Technical Phone # +61 2 9841 0555
Fax +61 2 9841 0500
Emergency Phone # +61 2 9841 0566
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
TBTC 1461-22-9 215-958-7 050-008-00-3
Formula C12H27ClSn
Molecular Weight 325.49 AMU
Synonyms Chlorid tri-n-butylcinicity (Czech) *
Chlorotributylstannane * Chlorotributyltin *
Monochlorotributyltin * Stannane,
tributylchloro- * Tin, tri-n-butyl-, chloride *
Tributylchlorotin * Tributylstannium chloride *
Tributylstannyl chloride * Tributyltin chloride
* Tri-n-butyltin chloride *
Tri-N-butylzinn-chlorid (German) * WR 3396
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Harmful in contact with skin. Toxic if swallowed. Irritating to
eyes and skin. Toxic: danger of serious damage to health by
prolonged exposure through inhalation and if swallowed. Very toxic
to aquatic organisms, may cause long-term adverse effects in the
aquatic environment.
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER SKIN CONTACT
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.
AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician immediately.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.
SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Absorb on sand or vermiculite and place in closed containers for
disposal. Ventilate area and wash spill site after material
pickup is complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe vapor. Do not get
in eyes, on skin, on clothing. Avoid prolonged or repeated
exposure.
STORAGE
Conditions of Storage: Keep tightly closed.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Use only in a chemical fume hood. Safety shower and eye bath.
GENERAL HYGIENE MEASURES
Wash contaminated clothing before reuse. Wash thoroughly after
handling.
EXPOSURE LIMITS - DENMARK
Source Type Value
OEL TWA 0.1 mg/m3
Remarks: SKIN
EXPOSURE LIMITS - GERMANY
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Source Type Value
TRGS 900 OEL 0.05 mg/m3
0.002 ppm
Remarks: 4
Remarks: H,Y
EXPOSURE LIMITS - SWITZERLAND
Source Type Value
OEL OEL 0.05 mg/m3
0.0021ppm*
Remarks: C
EXPOSURE LIMITS - UNITED KINGDOM
Source Type Value
OEL TWA 0.1MG(SN)/M3
OEL STEL 0.2 mg(Sn)/m3
Remarks: Skin
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
9 - Physical and Chemical Properties
Appearance Physical State: Clear liquid
Color: Very faintly yellow
Property Value At Temperature or Pressure
pH N/A
BP/BP Range 171 - 173 癈 25 mmHg
MP/MP Range N/A
Flash Point 113 癈 Method: closed cup
Flammability N/A
Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure N/A
SG/Density 1.207 g/cm3
Partition Coefficient N/A
Viscosity N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility N/A
10 - Stability and Reactivity
STABILITY
Stable: Stable.
Materials to Avoid: Strong oxidizing agents.
HAZARDOUS DECOMPOSITION PRODUCTS
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Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide,
Hydrogen chloride gas, Tin/tin oxides.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
RTECS NUMBER: WH6820000
ACUTE TOXICITY
LD50
Oral
Rat
129 mg/kg
LD50
Oral
Mouse
60 mg/kg
LD50
Oral
Rabbit
0.03 mg/kg
LD50
Oral
Hamster
147 mg/kg
Remarks: Peripheral Nerve and Sensation:Local anesthetic.
Behavioral:Tremor. Behavioral:Ataxia.
IRRITATION DATA
Eyes
Rabbit
0.05 mg
24H
Remarks: Severe irritation effect
SIGNS AND SYMPTOMS OF EXPOSURE
To the best of our knowledge, the chemical, physical, and
toxicological properties have not been thoroughly investigated.
ROUTE OF EXPOSURE
Skin Contact: Causes skin irritation.
Skin Absorption: Harmful if absorbed through skin. Readily
absorbed through skin.
Eye Contact: Causes severe eye irritation.
Inhalation: May be harmful if inhaled. Material may be
irritating to mucous membranes and upper respiratory tract.
Ingestion: Toxic if swallowed.
TARGET ORGAN INFORMATION
Blood. Liver. Kidneys.
CHRONIC EXPOSURE - MUTAGEN
Hamster
30 UG/L
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Cell Type: ovary
Other mutation test systems
CHRONIC EXPOSURE - REPRODUCTIVE HAZARD
Species: Rat
Dose: 65200 UG/KG
Route of Application: Oral
Exposure Time: (4-7D PREG)
Result: Effects on Fertility: Post-implantation mortality (e.g.,
dead and/or resorbed implants per total number of implants).
Species: Rat
Dose: 225 MG/KG
Route of Application: Oral
Exposure Time: (7-15D PREG)
Result: Effects on Fertility: Post-implantation mortality (e.g.,
dead and/or resorbed implants per total number of implants).
Effects on Embryo or Fetus: Fetal death.
Species: Rat
Dose: 321 MG/KG
Route of Application: Oral
Exposure Time: (13-15D PREG)
Result: Maternal Effects: Other effects. Effects on Embryo or
Fetus: Fetotoxicity (except death, e.g., stunted fetus).
Specific Developmental Abnormalities: Musculoskeletal system.
Species: Rat
Dose: 15 MG/KG
Route of Application: Oral
Exposure Time: (6-20D PREG)
Result: Effects on Newborn: Behavioral.
Species: Rat
Dose: 80 MG/KG
Route of Application: Oral
Exposure Time: (7-8D PREG)
Result: Maternal Effects: Other effects. Effects on Fertility:
Post-implantation mortality (e.g., dead and/or resorbed implants
per total number of implants).
Species: Rat
Dose: 100 MG/KG
Route of Application: Oral
Exposure Time: (8D PREG)
Result: Maternal Effects: Other effects. Effects on Fertility:
Post-implantation mortality (e.g., dead and/or resorbed implants
per total number of implants). Effects on Embryo or Fetus:
Fetotoxicity (except death, e.g., stunted fetus).
12 - Ecological Information
No data available.
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
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environmental regulations.
14 - Transport Information
RID/ADR
UN#: 2810
Class: 6.1
PG: III
Proper Shipping Name: Toxic liquid, organic, n.o.s.
IMDG
UN#: 2810
Class: 6.1
PG: III
Proper Shipping Name: Toxic liquid, organic, n.o.s.
Marine Pollutant: No
Severe Marine Pollutant: No
Technical Name: Required
IATA
UN#: 2810
Class: 6.1
PG: III
Proper Shipping Name: Toxic liquid, organic, n.o.s.
Inhalation Packing Group I: No
Technical Name: Required
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
ANNEX I INDEX NUMBER: 050-008-00-3
NOTA: A
INDICATION OF DANGER: T N
Toxic. Dangerous for the environment.
R-PHRASES: 21 25 36/38 48/23/25 50/53
Harmful in contact with skin. Toxic if swallowed. Irritating to
eyes and skin. Toxic: danger of serious damage to health by
prolonged exposure through inhalation and if swallowed. Very
toxic to aquatic organisms, may cause long-term adverse effects
in the aquatic environment.
S-PHRASES: 35 36/37/39 45 60 61
This material and its container must be disposed of in a safe
way. Wear suitable protective clothing, gloves, and eye/face
protection. In case of accident or if you feel unwell, seek
medical advice immediately (show the label where possible).
This material and its container must be disposed of as
hazardous waste. Avoid release to the environment. Refer to
special instructions/safety data sheets.
COUNTRY SPECIFIC INFORMATION
Germany
WGK: 3
SWITZERLAND
SWISS POISON CLASS: 3
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
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information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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