Material Safety Data Sheet
ISOPHTHALOYL CHLORIDE
Section 1 ?Product and Company Information
Substance : Isophthaloyl Chloride
Trade Name : Isophthaloyl Chloride
Chemical Family : Acid Chloride
Company : Shiva Pharmachem Pvt. Ltd.
Plot No. 588,
Village: Luna ?391440
Taluka: Padra
District: Vadodara, Gujarat
India.
Phone No. : +91 2662 221021 / 224360
Fax No. : +91 2662 223314
Section 2 ?Composition / Information on Ingredients
Product Name CAS No. EC No. Mol. Formula Mol. Weight
ISOPHTHALOYL Chloride 99-63-8 202-774-7 C8H4Cl2O2 203.02 g/mol
Section 3 ?Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Causes burns. Irritating to respiratory system.
Section 4 ?First Aid Measures
INHALATION
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult,
give oxygen.
SKIN CONTACT
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove
contaminated clothing and shoes. Call a physician.
EYE CONTACT
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure
adequate flushing by separating the eyelids with fingers. Call a physician.
INGESTION
If swallowed, wash out mouth with water provided person is conscious. Call a physician. Do not
induce vomiting.
Section 5 ?Fire Fighting Measures
CONDITIONS OF FLAMMABILITY
Water hydrolyzes material liberating acidic gas which in contact with metal surfaces can generate
flammable and/or explosive hydrogen gas.
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Material Safety Data Sheet
EXTINGUISHING MEDIA
Suitable: Carbon dioxide. Dry chemical powder.
Unsuitable: Do not use water.
SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and
eyes.
SPECIFIC METHOD(S) OF FIRE FIGHTING
Use water spray to cool fire-exposed containers.
Section 6 ?Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy rubber gloves.
METHODS FOR CLEANING UP
Cover with dry lime or soda ash, pick up, keep in a closed container, and hold for waste disposal.
Ventilate area and wash spill site after material pickup is complete.
Section 7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe vapor. Do not get in eyes, on skin, on clothing.
Avoid prolonged or repeated exposure.
STORAGE
Conditions of Storage: Keep tightly closed.
SPECIAL REQUIREMENTS
Moisture sensitive.
Section 8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Safety shower and eye bath. Use only in a chemical fume hood.
GENERAL HYGIENE MEASURES
Wash contaminated clothing before reuse. Discard contaminated shoes. Wash thoroughly after
handling.
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Use respirators and components tested and approved under appropriate
government standards such as NIOSH (US) or CEN (EU). Where risk assessment shows air-
purifying respirators are appropriate use a full-face particle respirator type N100 (US) or type P3
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Material Safety Data Sheet
(EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the sole
means of protection, use a full-face supplied air respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
Section 9 - Physical and Chemical Properties
Appearance Color : Colorless
Form : Crystals
Property : Value at Temperature or Pressure
PH : N/A
BP/BP Range : 276 癈 at 760 mmHg
MP/MP Range : 43 癈
Flash Point : 180 癈 Method: closed cup
Flammability : N/A
Autoignition Temp : N/A
Oxidizing Properties : N/A
Explosive Properties : N/A
Explosion Limits Lower : 1.5 %
Upper : 8.9 %
Vapor Pressure : N/A
1.388 g/cm3 at 20oC
SG/Density :
Partition Coefficient : N/A
Viscosity : N/A
Vapor Density : N/A
Saturated Vapor Conc. : N/A
Evaporation Rate : N/A
Bulk Density : N/A
Decomposition Temp. : N/A
Solvent Content : N/A
Water Content : N/A
Surface Tension : N/A
Conductivity : N/A
Miscellaneous Data : N/A
Solubility : N/A
Section 10 - Stability and Reactivity
STABILITY
Stable: Stable.
Conditions to Avoid: Moisture.
Materials to Avoid: Water, Alcohols, Oxidizing agents, Strong bases.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide, Hydrogen chloride gas,
Phosgene gas.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
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Material Safety Data Sheet
Section 11 - Toxicological Information
ACUTE TOXICITY
LD50
Oral
Rat
2200 mg/kg
LD50
Oral
Mouse
2221 mg/kg
Remarks: Behavioral: Food intake (animal). Behavioral: Change in motor activity (specific assay).
Behavioral: Somnolence (general depressed activity).
LD50
Oral
Rabbit
1175 mg/kg
Remarks: Behavioral: Food intake (animal). Behavioral: Change in motor activity (specific assay).
Behavioral: Somnolence (general depressed activity).
LD50
Skin
Rabbit
1410 mg/kg
IRRITATION DATA
Skin
Rabbit
200 mg
Remarks: Open irritation test Eyes
Rabbit
40 mg
Remarks: Mild irritation effect
SENSITIZATION
Sensitization: Prolonged or repeated exposure may cause allergic reactions in certain sensitive
individuals.
SIGNS AND SYMPTOMS OF EXPOSURE
Inhalation may result in spasm, inflammation and edema of the larynxand bronchi, chemical
pneumonitis, and pulmonary edema. Symptoms of exposure may include burning sensation,
coughing, wheezing, laryngitis, shortness of breath, headache, nausea, and vomiting. Material is
extremely destructive to tissue of the mucous membranes and upper respiratory tract, eyes, and
skin. To the best of our knowledge, the chemical, physical, and toxicological properties have not
been thoroughly investigated.
ROUTE OF EXPOSURE
Skin Contact
Causes burns.
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Material Safety Data Sheet
Skin Absorption
Harmful if absorbed through skin.
Eye Contact
Causes burns. Lachrymator.
Inhalation
Material is extremely destructive to the tissue of the mucous membranes and upper respiratory
tract. May be harmful if inhaled
Ingestion
May be harmful if swallowed.
Section 12 - Ecological Information
Not Available
Section 13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose of this material. Dissolve or mix
the material with a combustible solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local environmental regulations.
Section 14 - Transport Information
DOT Regulations
UN No. : 3096
Hazard Class : 8
PG : II
Proper Shipping Name : Corrosive solid, acidic, organic, n.o.s.
RID/ADR
UN No : 3261
Hazard Class : 8
PG : II
Proper Shipping Name : Corrosive solid, acidic, organic, n.o.s.
IMDG
UN No. : 3261
Hazard Class : 8
PG : II
Proper Shipping Name : Corrosive solid, acidic, organic, n.o.s.
Marine Pollutant : No
Severe Marine Pollutant : No
Technical Name : Required
IATA
UN No. : 3261
Hazard Class : 8
PG : II
Proper Shipping Name : Corrosive solid, acidic, organic, n.o.s.
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Material Safety Data Sheet
Inhalation Packing Group I : No
Technical Name : Required
Section 15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
INDICATION OF DANGER: C
Corrosive
R-PHRASES: 21-34-37
Harmful in contact with skin. Causes burns. Irritating to respiratory system.
S-PHRASES: 26-36/37/39-45
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing, gloves, and eye/face protection. In case of accident or if you
feel unwell, seek medical advice immediately.
COUNTRY SPECIFIC INFORMATION
Germany
WGK: 1
ID-Number: 7152
Section 16 - Additional Information
The information above is believed to be accurate and represents the best information currently
available to us. However, we make no warranty of merchantability or any other warranty, express
or implied, with respect to such information, and we assume no liability resulting from its use.
Users should make their own investigations to determine the suitability of the information for their
particular purposes. In no event shall Shiva Pharmachem Pvt. Ltd. be liable for any claims, losses,
or damages of any third party or for lost profits or any special, indirect, incident, consequential or
exemplary damages, howsoever arising, even if Shiva Pharmachem Pvt. Ltd has been advised of
the possibility of such damages.
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