Date: October 5, 2006
MATERIAL SAFETY DATA SHEET
1. CHEMICAL PRODUCT & COMPANY INFORMATION
PRODUCT IDENTITY: Ethylene Glycol
Chemical Name: Ethylene Glycol
Chemical Family: Glycol
Synonyms: M.E.G. Monoethylene Glycol; 1, 2-Dihydroxyethane;
1, 2-Ethanediol; Ethylene Dihydrate
Chemical Formula: C2H602
Formula Wt: 62.08
OLD WORLD INDUSTRIES, INC.
4065 COMMERCIAL AVENUE
NORTHBROOK, ILLINOIS 60062
PHONE: 847-559-2000
EMERGENCY PHONE: 1-800-424-9300 (CHEMTREC)
2. COMPOSITION / INFORMATION ON INGREDIENTS
MATERIAL CAS# % BY WT
Ethylene Glycol 107-21-1 99.5%
Diethylene Glycol 111-46-6 0.5%
Exposure Guidelines: OSHA STANDARDS - An employee's exposure to ethylene
glycol
shall at no time exceed the ceiling value of 50 ppm (125 mg/m3).
AGGIH THRESHOLD LIMIT VALUES - Ceiling Limit 50 ppm,
127 mg/m3 (1981) Vapor & mist
3. HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Appearance Colorless
Physical State Liquid
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Odor Sweet
Hazards of product HARMFUL OR FATAL IF SWALLOWED.
MAY CAUSE EYE IRRITATION
MAY CAUSE RESPIRATORY TRACT IRRITATION.
.
HAZARD RATING SYSTEM
NPFA: HEALTH: 1 FLAMMABILITY: 1 REACTIVITY: 0
KEY: 0 - Minimal, 1 - Slight, 2 - Moderate, 3 - Serious, 4 ?Severe
POTENTIAL HEALTH EFFECTS
Routes of Exposure: Skin, eyes, inhalation, ingestion.
Signs and Symptoms of Exposure: Incidental ingestion of small amounts of ethylene
glycol is not likely to cause any significant health
effects. Ingestion of large quantities may result in
irritability, mental sluggishness, dizziness, malaise,
abdominal or back pain. Changes in urine output
and appearance, fluid retention, jaundice (yellowish
skin color), kidney and liver damage, respiratory
failure, and
unconsciousness is evidence of severe poisoning.
Death may occur in extreme cases.
Skin: Contact with liquid may cause slight skin irritation.
Eyes: Contact with liquid may cause slight eye irritation.
Inhalation: Inhalation of mists or high concentrations of vapors
(e.g., from hot operations) may cause upper
respiratory tract irritation, headaches or nausea.
Ingestion: Ingestion of large quantities may be harmful, and in
extreme poisoning, may be fatal; causes central
nervous system depression, cardiopulmonary
effects, and kidney and liver damage. See "Signs
and Symptoms" for more information.
DELAYED/LONG TERM EFFECTS
Carcinogenic Effects: Ethylene glycol is not considered a carcinogen.
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Mutagenic: Ethylene glycol is not considered a mutagen.
Teratogenic: Ethylene glycol is considered to be an animal
teratogen based on studies in which high levels
were given in drinking water. Inhalation and dermal
exposure have not produced significant fetotoxicity
or malformations in animals. See Section 11,
"Toxicology", for further information.
Target Organ Effects: Central nervous system, kidney, liver, fetus.
Medical Conditions Exposure to this chemical may aggravate
preexisting skin and Aggravated by Exposure: respiratory conditions.
4. FIRST AID MEASURES
Ensure Physician Has Access To This MSDS.
4.3 Skin: Wash with soap and water after handling material.
If persistent irritation develops, get medical
attention.
4.2 Eyes: If eye contact occurs, flush with water. If persistent
irritation develops, get medical attention.
4.1 Inhalation: If inhaled, immediately remove victim to fresh air.
If effects occur, consult a physician.
4.4 Ingestion: If quantities of this material are swallowed,
immediately call physician. DO NOT induce
vomiting. Never give anything by mouth or induce
vomiting in an unconscious person. If person is
fully conscious give 1 cup or 8 ounces (240 ml) of
water. If medical advice is delayed and if an adult
has swallowed as 80 proof whiskey. For children,
give proportionally has liquor at a dose of 0.3
ounces (1 ?tsp) (8 ml) liquor for each 10 pounds of
body weight, or 2 ml per kg body weight [e.g., 1.2
ounce (2 1/3 Tbsp) for a 40 pound child or 36 ml for
an 18 kg child].
4.5 Note to Physicians: The principal toxic effects of ethylene glycol, when
swallowed, are kidney damage and metabolic
acidosis. Ethanol is antidotal, and early
administration may block the formation of toxic
metabolites of ethylene glycol in the liver. Ethanol
should be given intravenously, as a 5% solution in
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sodium bicarbonate, at a rate of about 10ml/hr. A
desired therapeutic level of ethanol in blood is
100mg/dl. Hemodialysis may be required.
Pulmonary edema with hypoxemia has been
described in a number of patients following
poisoning with ethylene glycol. The mechanism has
not been elucidated but it appears to be
noncardiogenic in origin in ventilation and positive
end expiratory pressure may be applied. Correction
of acidosis is essential.
5. FIRE FIGHTING MEASURES
FIRE & EXPLOSION HAZARD DATA
5.1 FLAMMABLE PROPERTIES
Flashpoint (TOC): 116oC (241oF)
Auto Ignition Temp: 398oC (748oF)
LEL: 3.2% by volume
UEL: 15.3% by volume
5.2 EXTINGUISHING MEDIA
Water fog or fine spray. Dry chemical fire extinguishers. Carbon dioxide fire
extinguishers. Foam. Do not use direct water stream. May spread fire. Alcohol resistant
foams (ATC type) are preferred. General purpose synthetic foams (including AFFF) or
protein foams may function, but will be less effective.
5.3 FIRE FIGHTING PROCEDURES
Keep people away. Isolate fire and deny unnecessary entry. Use water spray to cool fire
exposed containers and fire-affected zone until fire is out and danger of resignation has
passed. Fight fire from a protected location or safe distance. Consider the use of
unmanned hose holders or monitor nozzles. Immediately withdraw all personnel from
the area in case of rising sound from venting safety device or discoloration of the
container. Burning liquids may be extinguished by dilution with water. Do not use direct
water stream. May spread fire. Hand held dry chemical or carbon dioxide extinguishers
may be used for small fires. Move container from fire area if this is possible without
hazard. Burning liquids may be moved by flushing with water to protect personnel and
minimize property damage.
5.4 SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
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Wear positive-pressure self-contained breathing apparatus (SCBA) and protective fire
fighting clothing (includes fire fighting helmet, coat, pants, boots and gloves). If
protective equipment is not available or not used, fight fire from a protected location or
safe distance.
5.5 UNUSUAL FIRE AND EXPLOSION HAZARDS
Container may rupture from gas generation in a fire situation. Violent steam generation
or eruption may occur upon application of direct water stream to hot liquids.
5.6 HAZARDOUS COMBUSTION PRODUCTS
During a fire, smoke may contain the original material in addition to combustion products
of varying composition, which may be toxic and/or irritating. Combustion products may
include and are not limited to: Carbon monoxide. Carbon dioxide.
6. ACCIDENTAL RELEASE MEASURES
Small Spill: Absorb with materials such as: cat litter, sand,
sawdust. Vermiculite. Large spills: Dike area to
contain spill. Pump into suitable and properly
labeled containers.
Personal Precautions: Isolate area. Keep unnecessary and unprotected
personnel from entering the area. Use appropriate
safety equipment. For additional information, refer
to Section 8, Exposure Controls and Personal
Protection.
Environmental Precautions: Prevent from entering into soil, ditches, sewers,
waterways and/or groundwater.
7. HANDLING AND STORAGE
Keep containers tightly closed. Store in a cool, dry, well-ventilated location, away from
strong oxidizers, potential fire hazards, and incompatible chemicals.
8. PERSONAL PROTECTION
Respiratory Protection: Respiratory protection is required if airborne
concentration exceeds TLV. At any detectable
concentration, any self-contained breathing
apparatus with a full face piece and operated in a
pressure-demand or other positive pressure mode or
any supplied-air respirator with a full-face piece
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and operated in a pressure-demand or other positive
pressure mode in combination with an auxiliary
self-contained breathing apparatus operated in
pressure-demand or other positive pressure mode.
Skin Protection: Protective gloves recommended when prolonged
skin contact cannot be avoided. Polyethylene;
Neoprene, Nitrile, Polyvinyl alcohol; Natural
Rubber; Butyl Rubber. Safety shower should be
available.
Eye Protection: Safety goggles and face shield. Emergency eyewash
should be available. Contact lenses should not be
worn when working with this chemical.
Engineering Controls: Use general or local exhaust ventilation to meet
TLV requirements.
Special Precautions: Trace quantities of ethylene oxide (EO) may be
present in this product. While these trace quantities
could accumulate in the headspace areas of storage
transport vessels, they are not expected to create a
condition which will result in EO concentration
greater than 0.5 ppm (8 hour TWA) in the
breathing zone of the workplace for appropriate
applications. OSHA has established a permissible
exposure limit of 1.0 ppm 8 hour TWA for EO.
9. PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Appearance: Colorless
Odor: Sweet
Flash Point ?Closed Cup: 116癈 241癋 Tag Closed Cup ASTM D 56
Flammable Limits In Air:
Lower 3.2 %(V) apx
Upper 15.3 % (V) Estimated
Autoignition Temperature: 400 癈 752 癋
Vapor Pressure: 0.06 mmHg 20 癈
Boiling Point (760 mmHg): >197 癈 >387 癋
Vapor Density (air = 1): 2.2
Specific Gravity (H2O = 1): 1.115 20 癈 / 20 癈
Freezing Point: -13 癈 9 癋
Melting Point: Not applicable (for liquids)
Solubility in Water (by weight): 100%
Molecular Weight: 63 g/mol Approximately
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Evaporation Rate: (butyl acetate = 1): 0.01
10. STABILITY AND REACTIVITY
Stability: Stable under normal conditions of use.
Incompatibility: Strong oxidizing agents, strong acids and
polymerization catalysts. Contact of aqueous
ethylene glycol solution with DC-energized silvered
copper wires causes ignition of the latter. A mixture
of phosphorus (V) sulfide, ethylene glycol, and
hexane in a mantle-heated flask spontaneously
overheated and exploded at an internal temperature
of about 180癈. Mixing of equal weights of
ethylene glycol and potassium dichromate at 100癈
caused heat to evolve.
Hazardous Decomposition Acrid smoke and irritating fumes. Carbon monoxide
and
Products: carbon dioxide
Hazardous Polymerization: Will not occur
11. TOXICOLOGICAL INFORMATION
ACUTE TOXICITY
Peroral
Human; Lethal Dose; approximately 3 ounces (100 ml) (1/3 cup); (for ethylene glycol).
Peroral
Rat; LD50 = > 6000 mg/kg; Based on information for components(s).
Percutaneous
Rabbit; LD50 = > 22270 mg/kg
Inhalation
Rat; LC50 = > 3.95 mg/l; Aerosol, 7 hours, (for ethylene glycol)
DEVELOPMENTAL TOXICITY
Based on animal studies, ingestion of very large amounts of ethylene glycol appears to be
major and possibly only route of exposure to produce birth defects. Diethylene glycol
has caused toxicity to the fetus and some birth defects at maternally toxic, high doses in
animals. Other animal studies have not reproduced birth defects even at much higher
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doses that caused severe maternal toxicity. For ethylene glycol:, Exposures by inhalation
or skin contact, the primary routes of occupational exposure, had minimal effect on the
fetus, in animal studies.
REPRODUCTIVE TOXICITY
Ingestion of large amounts of ethylene glycol and diethylene glycol has been shown to
interfere with reproduction in animals.
CHRONIC TOXICITY AND CARCINOGENICITY
Ethylene glycol did not cause cancer in long-term animal studies., Diethylene glycol has
been tested for carcinogenicity in animal studies and is not believed to pose a
carcinogenic risk to man.
GENETIC TOXICOLOGY
In Vitro
For ethylene glycol and diethylene glycol:, In vitro mutagenicity studies were negative.
In Vivo
For ethylene glycol and diethylene glycol:, Animal mutagencity studies were negative.
SIGNIFICANT DATA WITH POSSIBLE RELEVANCE TO HUMANS
Effects have been reported in the following organs:
For ethylene glycol:
Observations in humans include:
Nystagmus (involuntary eye movement).
Repeated excessive exposure may cause irritation of the upper respiratory tract.
12. ECOLOGICAL INFORMATION
12.1 ENVIRONMENTAL FATE
Based largely or completely on information for: Ethylene glycol. Biodegradation
reached in Modified OECD Screening Test (OECD Test No. 301 E) after 28 days: >90%.
Biodegradation reached in Manometric Respirometry Test (OECD Test No. 301 F) after
28 days: >94%.
12.2 ECOTOXICITY
Based largely or completely on information for:, Ethylene glycol.
Toxicity to Micro-organisms
Bacterial/NA; 16 h; EC50
Result value: > 10000 mg/l
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Toxicity to Aquatic Invertebrates
water flea Ceriodaphnia dubia; LC50
Result value: (10000 ?25800) mg/l
Toxicity to Aquatic Plants
green alga Selenastrum capricomutum; Growth inhibition; EC50
Result value: (9500 ?13000) mg/l
Toxicity to Fish
rainbow trout (Oncorhynchus mykiss); LC50
Result value: (18000 ?46000) mg/l
Toxicity to Fish
bluegill (Lepornis macrochirus); LC50
Result value: 27540 mg/l
Toxicity to Fish
fathead minnow (Pimephales promelas); LC50
Result value: 51000 mg/l
13. DISPOSAL CONSIDERATIONS
DO NOT discharge to sewer. Wear appropriate personal protection. Take up with
sand, vermiculite, or similar inert material. Dispose in accordance with federal,
state and local regulations.
14. TRANSPORT INFORMATION
U. S. Department of Transportation (For Bulk Shipment Only)
Proper Shipping Name: Other regulated substance
Liquid, NOS (Ethylene Glycol)
Hazard Class: 9 ID No: UN3082
Label: Miscellaneous RQ Product Packaging Group:III
Shipments with individual packages, i.e. drums, pails or gallons, containing less than RQ
(5313 pounds) not subjected to regulation.
15. REGULATORY INFORMATION
15.1 FEDERAL / NATIONAL
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OSHA Hazard Communication Standard
This product is a "Hazardous Chemical" as defined by the OSHA Hazard
Communication Standard, 29 CFR 1910.1200.
Superfund Amendments and Reauthorization Act of 1986 Title III (Emergency Planning
and Community Right to Know Act) Section 313
This product contains the following substances subject to the reporting requirements of
Section 313 of Title III of the Superfund Amendments and Reauthorization Act 1986 and
40 CFR Part 372.
Component CAS # Amount
Ethylene glycol 107-21-1 99.5000%
Superfund Amendments and Reauthorization Act of 1986 Title III (Emergency Planning
and Community Right to Know Act) Section 302
To the best of our knowledge this product does not contain chemicals at levels, which
require reporting under this statute.
Superfund Amendments and Reauthorization Act of 1986 Title III (Emergency Planning
and Community Right to Know Act) Section 311 And 312
Delayed (Chronic) Health Hazard : Yes
Fire Hazard : No
Immediate (Acute) Health Hazard : Yes
Reactive Hazard : No
Sudden Release of Pressure Hazard : No
Tonic Substances Control Act (TSCA)
All components of this product are on the TSCA inventory or are exempt from TSCA
Inventory requirements.
CEPA ?Domestic Substances List (DSL)
All substances contained in this product are listed on the Canadian Domestic Substances
List (DSL) or are not required to be listed.
European Inventory of Existing Commercial Chemical Substances (EINECS)
The components of this product are on the EINECS Inventory or are exempt fro EINECS
inventory requirements.
15.2 STATE / LOCAL
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Pennsylvania (Worker And Community Right To Know Act): Pennsylvania Hazardous
Substances List And/Or Pennsylvania Environmental Hazardous Substance List:
The following product components are cited in the Pennsylvania Hazardous Substances
List and/or the Pennsylvania Environmental Substance List, and are present at levels
which require reporting.
Component CAS # Amount
Ethylene glycol 107-21-1 99.5000%
Diethylene glycol 111-46-6 0.5000%
Pennsylvania (Worker And Community Right To Know Act): Pennsylvania Special
Hazardous Substances List:
To the best of our knowledge this product does not contain chemicals at levels which
require reporting under this statute.
California Proposition 65 (Safe Drinking Water And Toxic Enforcement Act Of 1986)
Meets current guidelines of allowable limits as of the July 11, 2003 listing.
Component CAS # Amount
1.4-Dioxane 123-91-1 <0.000075%
Aetaldehyde 75-07-0 <0.00038%
California SCAQMD Rule 443.1 (South Coast Air Quality Management District Rule
443.1, Labeling of Materials Containing Organic Solvents)
VOC: Vapor pressure 0.06 mmHg at 20 癈
1113.38 g/l
16. OTHER INFORMATION
NFPA ratings for this product are: H - 1 F? R?
Contact: Karen Engelbrecht Phone: (847) 559-2000
Old World Industries, Inc. makes no warranty, representation or guarantee as to the accuracy, sufficiency or completeness of the
material set forth herein. It is the user's responsibility determines the safety, toxicity and suitability of his own use, handling and
disposal of this product. Since actual use by others is beyond our control, no warranty, expressed or implied, is made by Old World
Industries, Inc. as to the effects of such use, the results to be obtained or the safety and toxicity of this product, nor does Old World
Industries, Inc. assume liability arising out of the use by others of this product referred to herein. The data in this MSDS relates only
to the specific material designated herein and does not relate to use in combination with any other material or in any process.
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