Commercial Food Equipment Service Association P_ 0000007346 D_0000007352
Forane (R) 12
Material Safety Data Sheet
ATOFINA Chemicals, Inc.
1 PRODUCT AND COMPANY IDENTIFICATION
EMERGENCY PHONE NUMBERS:
Fluorochemicals Group
Chemtrec: (800) 424-9300 (24hrs) or (703) 527-3887
2000 Market Street
Medical: Rocky Mountain Poison Control Center
(303) 623-5716 (24Hrs)
Philadelphia, PA 19103
Information Telephone Numbers Phone Number Available Hrs
Product Information 800-245-5858 8:00 am - 5:30 pm (Eastern)
Product Name Forane (R) 12
Product Synonym(s) A list of applicable product can be found in Section 16
Chemical Family Chlorofluorocarbons
Chemical Formula CCl2F2
Chemical Name Dichlorodifluoromethane (CFC - 12)
EPA Reg Num
Product Use Refrigerant, Medical Inhaler Propellant
2 COMPOSITION / INFORMATION ON INGREDIENTS
Ingredient Name CAS RegistryNumber Typical Wt. % OSHA
Dichlorodifluoromethane (R-12) 75-71-8 100% Y
The substance(s) marked with a "Y" in the OSHA column, are identified as hazardous chemicals according to the
criteria of the OSHA Communication Standard (29 CFR 1910.1200)
This material is classified as hazardous under Federal OSHA regulation.
The components of this product are all on the TSCA inventory list.
3 HAZARDS IDENTIFICATION
Emergency Overview
Colorless liquified gas with faint ether odor.
WARNING!
LIQUID AND GAS UNDER PRESSURE, OVERHEATING AND OVERPRESSURIZING MAY CAUSE GAS RELEASE
OR VIOLENT CYLINDER BURSTING. MAY DECOMPOSE ON CONTACT WITH FLAMES OR EXTREMELY HOT
METAL SURFACES TO PRODUCE TOXIC AND CORROSIVE PRODUCTS. VAPOR REDUCES OXYGEN
AVAILABLE FOR BREATHING AND IS HEAVIER THAN AIR. HARMFUL IF INHALED AND MAY CAUSE HEART
IRREGULARITIES, UNCONSCIOUSNESS OR DEATH. LIQUID CONTACT WITH EYES OR SKIN MAY CAUSE
FROSTBITE.
Potential Health Effects
Inhalation and skin contact are expected to be the primary routes of occupational exposure to this material. Based on
single exposure animal tests, this material is considered to be no more than slightly toxic if swallowed, practically non-
toxic if inhaled and practically non-irritating to eyes and skin. As with most liquified gases, contact with the rapidly
volatilizing liquid or cold vapor can cause frostbite to any tissue. High vapor concentrations are irritating to the eyes
and respiratory tract and may result in central nervous system (CNS) effects such as headache, dizziness, anesthesia,
drowsiness and, in severe exposure, loss of consciousness and death. The dense vapor of this material may reduce
the available oxygen for breathing and produce symptoms such as headache, dizziness, drowsiness, cyanosis and lack
of muscle control followed by collapse. Prolonged exposure to an oxygen-deficient atmosphere may be fatal.
Product Code: 04012 Page 1
Revision: 7 Issued: 26 SEP 2001 of 7
Commercial Food Equipment Service Association P_ 0000007346 D_0000007352
Forane (R) 12
Material Safety Data Sheet
ATOFINA Chemicals, Inc.
Inhalation of this material may cause an increase in the sensitivity of the heart to adrenaline, which could result in
irregular or rapid heartbeats and reduced heart function. Workers with heart disease or compromised heart function
should limit exposure to this material.
4 FIRST AID MEASURES
IF IN EYES, immediately flush with plenty of water. Get medical attention if irritation persists.
IF ON SKIN, Flush exposed skin with lukewarm water (not hot), or use other means to warm skin slowly. Get
medical attention if frostbitten by liquid or if irritation occures.
IF SWALLOWED, Not applicable - product is a gas at ambient temperatures.
IF INHALED, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give
oxygen. Get medical attention. Do not give adrenaline, epinephrin or similar drugs following exposure to this
product.
5 FIRE FIGHTING MEASURES
Fire and Explosive Properties
Auto-Ignition Temperature NA
Flash Point NA - GAS Flash Point Method
Flammable Limits- Upper NA
NA
Lower
Extinguishing Media
Use extinguishing media appropriate to surrounding fire conditions.
Fire Fighting Instructions
Stop the flow of gas if possible. Use water spray on person making shut-off. Fire fighters and others who may
be exposed to products of combustion should wear full fire fighting turn out gear (full Bunker Gear) and self-
contained breathing apparatus (pressure demand NIOSH approved or equivalent). Fire fighting equipment
should be thoroughly decontaminated after use.
Fire and Explosion Hazards
May decompose on contact with flames or extremely hot metal surfaces to produce toxic and corrosive
products. Liquid and gas under pressure, overheating or overpressurizing may cause gas release and/or violent
cylinder bursting. Container may explode if heated due to resulting pressure rise. Some mixtures of HCFCs
and/or HFCs, and air or oxygen may be combustible if pressurized and exposed to extreme heat or flame.
6 ACCIDENTAL RELEASE MEASURES
In Case of Spill or Leak
Use Halogen leak detector or other suitable means to locate leaks or check atmosphere. Keep upwind.
Evacuate enclosed spaces and disperse gas with floor-level forced-air ventilation. Exhaust vapors outdoors.
Do not smoke or operate internal combustion engines. Remove flames and heating elements.
7 HANDLING AND STORAGE
Product Code: 04012 Page 2
Revision: 7 Issued: 26 SEP 2001 of 7
Commercial Food Equipment Service Association P_ 0000007346 D_0000007352
Forane (R) 12
Material Safety Data Sheet
ATOFINA Chemicals, Inc.
7 HANDLING AND STORAGE
Handling
Avoid breathing gas. Avoid contact with eyes, skin and clothing. Keep container closed. Use only with
adequate ventilation. Do not enter confined spaces unless adequately ventilated.
Storage
Do not apply direct flame to cylinder. Do not store cylinder in direct sun or expose it to heat above 120 F. Do
not drop or refill this cylinder. Keep away from heat, sparks and flames.
8 EXPOSURE CONTROLS / PERSONAL PROTECTION
Engineering Controls
Investigate engineering techniques to reduce exposures below airborne exposure limits. Provide ventilation if
necessary to control exposure levels below airborne exposure limits (see below). If practical, use local
mechanical exhaust ventilation at sources of air contamination such as open process equipment.
Eye / Face Protection
Where there is potential for eye contact, wear chemical goggles and have eye flushing equipment available.
Skin Protection
Wear appropriate chemical resistant protective clothing and chemical resistant gloves to prevent skin contact.
Consult glove manufacturer to determine appropriate type glove material for given application. Rinse
contaminated skin promptly. Wash contaminated clothing and clean protective equipment before reuse. Wash
skin thoroughly after handling.
Respiratory Protection
Avoid breathing gas. When airborne exposure limits are exceeded (see below), use NIOSH approved
respiratory protection equipment appropriate to the material and/or its components (full facepiece
recommended). Consult respirator manufacturer to determine appropriate type equipment for a given
application. Observe respirator use limitations specified by NIOSH or the manufacturer. For emergency and
other conditions where exposure limit may be significantly exceeded, use an approved full face positive-
pressure, self-contained breathing apparatus or positive-pressure airline with auxiliary self-contained air supply.
Respiratory protection programs must comply with 29 CFR 搂 1910.134.
Airborne Exposure Guidelines for Ingredients
Exposure Limit Value
Dichlorodifluoromethane (R-12)
ACGIH TWA - 1000 ppm 4950 mg/m3
OSHA TWA PEL - 1000 ppm 4950 mg/m3
-Only those components with exposure limits are printed in this section.
-Skin contact limits designated with a "Y" above have skin contact effect. Air sampling alone is insufficient to accurately quantitate
exposure. Measures to prevent significant cutaneous absorption may be required.
-ACGIH Sensitizer designator with a value of "Y" above means that exposure to this material may cause allergic reactions.
-WEEL-AIHA Sensitizer designator with a value of "Y" above means that exposure to this material may cause allergic skin reactions.
Product Code: 04012 Page 3
Revision: 7 Issued: 26 SEP 2001 of 7
Commercial Food Equipment Service Association P_ 0000007346 D_0000007352
Forane (R) 12
Material Safety Data Sheet
ATOFINA Chemicals, Inc.
9 PHYSICAL AND CHEMICAL PROPERTIES
Colorless liquified gas with faint ether odor.
Appearance/Odor
pH NA
Specific Gravity 1.31 @ 4 C
Vapor Pressure 84.9 PSIA @ 21 C/70 F
Vapor Density 4.17
Melting Point NE
Freezing Point -157.8 C (-252 F)
Boiling Point -29.8 C (-21.6 F)
Solubility In Water Slight
Percent Volatile 100
Molecular Weight 120.91
Bulk Density 1.31 @ 25 C (g/cm3)
10 STABILITY AND REACTIVITY
Stability
This material is chemically stable under specified conditions or storage, shipment and/or use. See
HANDLING AND STORAGE section of this MSDS for specified conditions.
Incompatibility
Avoid contact with strong alkali or alkaline earth metals, finely powdered metals such as aluminum, magnesium
or zinc and strong oxidizers, since they may react or accelerate decomposition.
Hazardous Decomposition Products
Thermal decomposition products include hydrogen fluoride, hydrogen chloride,
carbon monoxide, carbon dioxide and chlorine.
11 TOXICOLOGICAL INFORMATION
Toxicological Information
No adverse effects were reported in human volunteers following inhalation of 1000 ppm for 1-60 minutes, while
inhalation of 10,000 ppm for 2.5 hours resulted in a 7% reduction in psychological performance. Individuals
exposed for a short time (14-18 minutes) to a high concentration (40,000 ppm) reported a tingling sensation,
humming in the ears, electrocardiogram changes, a feeling of apprehension, decreased psychological test
scores and slurred speech. Exposure to 110,000 ppm for 10 minutes caused partial loss of consciousness with
amnesia and heart arrhythmia in one individual.
Repeated spraying of a 40% solution of this material in sesame oil daily for 12 applications had no effect on skin
of rabbits. This material sprayed directly on the skin, tongue, soft palate and in the ear canal of rats, 1-2 times
per day, for 5-6 weeks showed only evidence of slight skin irritation. A number of acute studies with dogs, rats,
mice, rabbits and monkeys have shown that inhalation exposure to high levels of this material caused
anesthesia, heart arrhythmia, reduced heart function, effects on blood pressure, heart sensitization to
adrenaline and other effects on the heart and respiratory systems in most animal species. Subacute inhalation
studies have shown few adverse effects. No pathologic changes were reported in guinea pigs, rats, cats and
dogs following inhalation of 100,000 ppm of this material for 4-weeks. In longer-term (13-week) inhalation
studies, liver changes occurred in guinea pigs at 4000 ppm, while 810 ppm was without effect in dogs,
Product Code: 04012 Page 4
Revision: 7 Issued: 26 SEP 2001 of 7
Commercial Food Equipment Service Association P_ 0000007346 D_0000007352
Forane (R) 12
Material Safety Data Sheet
ATOFINA Chemicals, Inc.
11 TOXICOLOGICAL INFORMATION
monkeys, rats or rabbits, but guinea pigs showed microscopic liver injury. Inhalation of very high concentrations
(100,000 ppm) for similar time periods (10-12 weeks) produced tremors, signs of mild narcosis and some blood
changes in guinea pigs, dogs and monkeys. Following oral dosing of rats and dogs with this material at 160-379
mg/kg/day and 84-95 mg/kg/day, respectively, for about 12 weeks, no adverse effects were reported. No
adverse effects were reported in dogs following long-term (2-year) dietary administration of this material at
levels up to 80 mg/kg/day. Reduced body weight gain in female rats was the only effect reported with long-term
oral dosing (2-years) of rats at levels up to 150 mg/kg/day. Long-term oral dosing at higher dosages (1000
mg/kg/day to rats and 3925 mg/kg/day to mice) reduced animal survival. This material produced no tumors in
any of these studies. No birth defects or embryotoxicity were noted in rats given this material orally during
pregnancy at levels up to 170 mg/kg/day. No birth defects were noted in rats or rabbits exposed to a mixture of
90% of this material and 10% trichlorofluoromethane by inhalation during pregnancy at a concentration of
200,000 ppm. No effects were seen on the ability of male or female rats to reproduce when given this material
in corn oil orally at levels up to 150 mg/kg/day for 3 successive generations. This material produced no genetic
changes in standard tests using animals and animal or bacterial cells. This material diffuses rapidly into the
blood and is rapidly eliminated almost completely from the lungs by exhaled air. Human volunteers eliminated
about 90% of inhaled this material within 30 minutes after inhalation of a single breath of the material. Single
exposure (acute) studies indicate:
Oral - No More Than Slightly Toxic to Rats (LD50 > 1,000 mg/kg)
Inhalation - Practically Non-toxic to Mice (3-hr LC50 620,000 ppm)
Inhalation - Practically Non-toxic to Rats (30-min LC50 > 800,000 ppm)
12 ECOLOGICAL INFORMATION
Ecotoxicological Information
No data are available.
Chemical Fate Information
This material is biodegradable in anaerobic environments. The log octanol/water partition coefficient is 2.08-
2.16.
13 DISPOSAL CONSIDERATIONS
Waste Disposal
Recover, reclaim or recycle when practical. Dispose of in accordance with federal, state and local regulations.
Note: Chemical additions to, processing of, or otherwise altering this material may make this waste
management information incomplete, inaccurate, or otherwise inappropriate. Furthermore, state and local
waste disposal requirements may be more restrictive or otherwise different from federal laws and regulations.
Product Code: 04012 Page 5
Revision: 7 Issued: 26 SEP 2001 of 7
Commercial Food Equipment Service Association P_ 0000007346 D_0000007352
Forane (R) 12
Material Safety Data Sheet
ATOFINA Chemicals, Inc.
14 TRANSPORT INFORMATION
DOT Name Dichlorodifluoromethane
DOT Technical Name (R-12)
DOT Hazard Class 2.2
UN Number UN 1028
DOT Packing Group PG NA
RQ
15 REGULATORY INFORMATION
Hazard Categories Under Criteria of SARA Title III Rules (40 CFR Part 370)
Immediate (Acute) Health Y Fire N
Reactive
Delayed (Chronic) Health N N
Sudden Release of Pressure Y
The components of this product are all on the TSCA inventory list.
Ingredient Related Regulatory Information:
SARA Reportable Quantities CERCLA RQ SARA TPQ
Dichlorodifluoromethane (R-12) 5000 LBS
SARA Title III, Section 313
This product does contain chemical(s) which are defined as toxic chemicals under and subject to the reporting requirements of, Section
313 of Title III of the Superfund Ammendments and Reauthorization Act of 986 and 40 CFR Part 372. See Section 2
Dichlorodifluoromethane (R-12)
Massachusetts Right to Know
This product does contain the following chemicals(s), as indicated below, currently on the Massachusetts Right to Know Substance
List.
Dichlorodifluoromethane (R-12)
New Jersey Right to Know
This product does contain the following chemical(s), as indicated below, currently on the New Jersey Right-to-Know Substances List.
Dichlorodifluoromethane (R-12)
Pennsylvania Environmental Hazard
This product does contain the following chemical(s), as indicated below, currently on the Pennsylvania Environmental Hazard List.
Dichlorodifluoromethane (R-12)
Pennsylvania Right to Know
This product does contain the following chemical(s), as indicated below, currently on the Pennsylvania Hazardous Substance List.
Dichlorodifluoromethane (R-12)
16 OTHER INFORMATION
Product Code: 04012 Page 6
Revision: 7 Issued: 26 SEP 2001 of 7
Commercial Food Equipment Service Association P_ 0000007346 D_0000007352
Forane (R) 12
Material Safety Data Sheet
ATOFINA Chemicals, Inc.
Revision Information
Revision Number 7
26 SEP 2001
Revision Date
Supercedes Revision Dated 20-SEP-2001
Revision Summary
Updated due to changes in regulatory information.
Key
NE= Not Established NA= Not Applicable (R) = Registered Trademark
Miscellaneous
This MSDS applies to the following:
CFC-12, R-12, Food Freezant 12, Isotron 12
ATOFINA Chemicals, Inc. believes that the information and recommendations contained herein (including data
and statements) are accurate as of the date hereof. NO WARRANTY OF FITNESS FOR ANY PARTICULAR
PURPOSE, WARRANTY OF MERCHANTABILITY, OR ANY OTHER WARRANTY, EXPRESSED OR
IMPLIED, IS MADE CONCERNING THE INFORMATION PROVIDED HEREIN. The information provided
herein relates only to the specific product designated and may not be valid where such product is used in
combination with any other materials or in any process. Further, since the conditions and methods of use are
beyond the control of ATOFINA Chemicals, ATOFINA Chemicals expressly disclaims any and all liability as to
any results obtained or arising from any use of the product or reliance on such information.
Product Code: 04012 Page 7
Revision: 7 Issued: 26 SEP 2001 of 7
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