SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 06/FEB/2005
Date Updated: 13/MAR/2004
Version 1.4
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name BIPHENYL, 99.5%
Product Number B34656
Company Sigma-Aldrich Pty, Ltd
Unit 2, 14 Anella Avenue
Castle Hill NSW 1765
Australia
Technical Phone # +61 2 9841 0555
Fax +61 2 9841 0500
Emergency Phone # +61 2 9841 0566
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
BIPHENYL 92-52-4 202-163-5 601-042-00-8
Formula C12H10
Molecular Weight 154.21 AMU
Synonyms Bibenzene * 1,1'-Biphenyl * Biphenyl
(ACGIH:OSHA) * Carolid AL * CP 390 * Diphenyl
(OSHA) * Lemonene * MCS 1572 * Phenador-X *
Phenylbenzene * PHPH * Tetrosin LY * Xenene
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Irritating to eyes, respiratory system and skin. Very toxic to
aquatic organisms, may cause long-term adverse effects in the
aquatic environment.
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER SKIN CONTACT
In case of contact, immediately wash skin with soap and copious
amounts of water.
AFTER EYE CONTACT
In case of contact, immediately flush eyes with copious amounts
of water for at least 15 minutes.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Carbon dioxide, dry chemical powder, or appropriate
foam.
SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear respirator, chemical safety goggles, rubber boots, and
heavy rubber gloves.
METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Avoid
raising dust. Ventilate area and wash spill site after material
pickup is complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe dust. Avoid contact
with eyes, skin, and clothing. Avoid prolonged or repeated
exposure.
STORAGE
Conditions of Storage: Keep tightly closed.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Safety shower and eye bath. Mechanical exhaust required.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling.
EXPOSURE LIMITS
Country Source Type Value
Poland NDS 1 mg/m3
Poland NDSCh 2 mg/m3
EXPOSURE LIMITS - DENMARK
Source Type Value
OEL TWA 1 mg/m3
0.2 ppm
EXPOSURE LIMITS - GERMANY
Source Type Value
TRGS 900 OEL 1 mg/m3
0.2 ppm
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EXPOSURE LIMITS - NORWAY
Source Type Value
OEL 1 mg/m3
0.2 ppm
EXPOSURE LIMITS - SWEDEN
Source Type Value
LLV (Level1.3 mg/m3
0.2 ppm
EXPOSURE LIMITS - SWITZERLAND
Source Type Value
OEL OEL 1.3 mg/m3
0.2 ppm
Remarks: D
EXPOSURE LIMITS - UNITED KINGDOM
Source Type Value
OEL OEL 1.3 mg/m3
0.2 ppm
OEL STEL 3.8 mg/m3
0.6 ppm
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
9 - Physical and Chemical Properties
Appearance Physical State: Solid
Color: Faintly yellow
Form: Fine crystals
Property Value At Temperature or Pressure
pH N/A
BP/BP Range 255 掳C 760 mmHg
MP/MP Range 68 掳C
Flash Point 110 掳C Method: closed cup
Flammability N/A
Autoignition Temp 540 掳C
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits Lower: 0.6 %
Upper: 5.8 %
Vapor Pressure N/A
SG/Density 0.992 g/cm3
Partition Coefficient N/A
Viscosity N/A
Vapor Density 5.31 g/l
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility N/A
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10 - Stability and Reactivity
STABILITY
Stable: Stable.
Materials to Avoid: Strong oxidizing agents.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
RTECS NUMBER: DU8050000
ACUTE TOXICITY
LD50
Oral
Rat
2140 mg/kg
Remarks: Behavioral:Somnolence (general depressed activity).
Behavioral:Muscle weakness. Gastrointestinal:Alteration in
gastric secretion.
LD50
Oral
Mouse
1900 mg/kg
Remarks: Behavioral:Somnolence (general depressed activity).
Gastrointestinal:Hypermotility, diarrhea.
LD50
Intravenous
Mouse
56 MG/KG
LD50
Oral
Cat
> 2600 mg/kg
LD50
Oral
Rabbit
2400 mg/kg
LD50
Skin
Rabbit
> 5010 mg/kg
IRRITATION DATA
Skin
Rabbit
0.5 ml
24H
Remarks: Severe irritation effect
Eyes
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Rabbit
100 mg
Remarks: Mild irritation effect
SIGNS AND SYMPTOMS OF EXPOSURE
Damage to the liver. Exposure can cause: Gastrointestinal
disturbances.
ROUTE OF EXPOSURE
Skin Contact: Causes skin irritation.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: Causes eye irritation.
Inhalation: Material is irritating to mucous membranes and upper
respiratory tract. May be harmful if inhaled.
Ingestion: May be harmful if swallowed.
TARGET ORGAN INFORMATION
Liver. Central nervous system. Peripheral nervous system.
CONDITIONS AGGRAVATED BY EXPOSURE
May cause nervous system disturbances.
CHRONIC EXPOSURE - CARCINOGEN
Mouse
Route of Application: Oral
Result: Tumorigenic:Equivocal tumorigenic agent by RTECS
criteria. Lungs, Thorax, or Respiration:Tumors. Blood:Tumors.
Mouse
Route of Application: Subcutaneous
Result: Tumorigenic:Neoplastic by RTECS criteria. Lungs, Thorax,
or Respiration:Tumors. Liver:Tumors.
CHRONIC EXPOSURE - MUTAGEN
Rat
8400 MG/KG
Oral
4W
Unscheduled DNA synthesis
Mouse
20 UMOL/L (+S9)
Cell Type: lymphocyte
Mutation in microorganisms
Mouse
50 UMOL/L
Cell Type: lymphocyte
DNA damage
Mouse
2 GM/KG
Oral
DNA damage
Mouse
296 UMOL/L
Cell Type: lymphocyte
Mutation in mammalian somatic cells.
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Hamster
10 MG/L (+S9)
Cell Type: lung
Mutation in microorganisms
Hamster
10 MG/L
Cell Type: lung
Cytogenetic analysis
Hamster
100 UMOL/L
Cell Type: fibroblast
Sister chromatid exchange
12 - Ecological Information
No data available.
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
environmental regulations.
14 - Transport Information
RID/ADR
UN#: 3077
Class: 9
PG: III
Proper Shipping Name: Environmentally hazardous
substance, solid, n.o.s
IMDG
UN#: 3077
Class: 9
PG: III
Proper Shipping Name: Environmentally hazardous
substance, solid, n.o.s
Marine Pollutant: Yes
Severe Marine Pollutant: No
Technical Name: Required
IATA
UN#: 3077
Class: 9
PG: III
Proper Shipping Name: Environmentally hazardous
substance, solid, n.o.s
Inhalation Packing Group I: No
Technical Name: Required
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
ANNEX I INDEX NUMBER: 601-042-00-8
INDICATION OF DANGER: Xi N
Irritant. Dangerous for the environment.
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R-PHRASES: 36/37/38 50/53
Irritating to eyes, respiratory system and skin. Very toxic to
aquatic organisms, may cause long-term adverse effects in the
aquatic environment.
S-PHRASES: 23 60 61
Do not breathe vapor. This material and its container must be
disposed of as hazardous waste. Avoid release to the
environment. Refer to special instructions/safety data sheets.
COUNTRY SPECIFIC INFORMATION
Germany
WGK: 2
SWITZERLAND
SWISS POISON CLASS: 4
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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