ISO9001:2000 Certified
Material Safety Data Sheet
Methyl Red TS
Section 1 - Chemical Product and Company Identification
MSDS Name:
Methyl Red TS
Catalog Numbers:
LC17150
Synonyms:
Methyl Red, 0.1% in Ethanol
Company Identification:
LabChem Inc
200 William Pitt Way
Pittsburgh, PA 15238
Company Phone Number:
(412) 826-5230
Emergency Phone Number:
(800) 424-9300
CHEMTREC Phone Number:
(800) 424-9300
Section 2 ?Composition, Information on Ingredients
CAS# Chemical Name: Percent
493-52-7 Methyl Red Free Acid 0.1
7732-18-5 Water 5
64-17-5 Ethanol balance
Section 3 - Hazards Identification
Emergency Overview
Appearance: Clear, orange solution.
Danger! Flammable liquid and vapor. Causes severe eye and moderate skin irritation. Causes
respiratory and digestive tract irritation. This substance has caused adverse reproductive and fetal
effects in humans. May cause central nervous system depression. May cause liver, kidney and heart
damage.
Target Organs: Kidneys, heart, central nervous system, liver.
Potential Health Effects
Eye:
May cause severe eye irritation. May cause painful sensitization to light. May cause chemical
conjunctivitis and corneal damage.
Skin:
Causes moderate skin irritation. May cause cyanosis of the extremities.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause systemic
toxicity with acidosis. May cause central nervous system depression, characterized by excitement,
-1-
Material Safety Data Sheet
Methyl Red TS
followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse,
unconsciousness, coma, and death du to respiratory failure.
Inhalation:
Causes respiratory tract irritation. May cause narcotic effects in high concentration. Vapors may
cause dizziness or suffocation. Inhalation of high concentrations causes effects similar to those
from ingestion.
Chronic:
May cause reproductive and fetal effects. Laboratory experiments have resulted in mutagenic
effects. Animal studies have reported the development of tumors. Prolonged exposure may cause
liver, kidney, and heart damage.
Section 4 - First Aid Measures
Eyes:
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower
eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing
contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Call a poison control center. If swallowed, do not induce vomiting unless directed to do so by
medical personnel. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial
respiration using a one-way valve or other suitable device. Do not use mouth to mouth respiration.
If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively. Persons with skin or eye disorders, liver, kidney, chronic
respiratory, or central or peripheral nervous system diseases may be at increased risk of exposure to
this substance.
Antidote:
Replace fluid and electrolytes.
Section 5 - Fire Fighting Measures
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH
(approved or equivalent), and full protective gear. Substance is flammable. Vapors may form an
explosive mixture with air. Vapors can travel to a source of ignition and flash back. Will burn if
involved in a fire. Can release vapors that form explosive mixtures at temperatures above the
flashpoint. Use water spray to keep fire-exposed containers cool. Containers may explode in the
heat of a fire.
Extinguishing Media:
In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
Autoignition Temperature:
363?C (685?F)
Flash Point:
16.7?C (62?F)
NFPA Rating:
(estimated) Health: 2; Flammability: 3; Instability: 0
-2-
Material Safety Data Sheet
Methyl Red TS
Explosion Limits:
Lower: 3.3% Upper: 19.0%
Section 6 - Accidental Release Measures
General Information:
Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Clean up spills immediately, observing precautions in the Protective Equipment section. Absorb
spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Remove all
sources of ignition. Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be
used to reduce vapors.
Section 7 - Handling and Storage
Handling:
Wash thoroughly after handling. Use only in a well-ventilated area. Ground and bond containers
when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact
with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and
can be dangerous. Keep container tightly closed. Keep away from heat, sparks and flame. Avoid
ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty
containers to heat, sparks or open flames.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly
closed container. Keep from contact with oxidizing materials. Store in a cool, dry, well-ventilated
area away from incompatible substances. Flammables-area. Do not store near perchlorates,
peroxides, chromic acid or nitric acid.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety
shower. Use explosion-proof ventilation equipment. Use adequate ventilation to keep airborne
concentrations low.
Exposure Limits:
Chemical Name: ACGIH NIOSH OSHA
Methyl red sodium salt none listed none listed none listed
Water none listed none listed none listed
Ethanol 1000 ppm TWA 1000 ppm TWA; 1000 ppm TWA;
1900 mg/m3 TWA 1900 mg/m3 TWA
3300 ppm IDLH
OSHA Vacated PELs:
Methyl red: No OSHA Vacated PELs are listed for this chemical.
Water: No OSHA Vacated PELs are listed for this chemical.
Ethanol: 1000 ppm TWA; 1900 mg/m3 TWA
-3-
Material Safety Data Sheet
Methyl Red TS
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and
face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149.
Use a NIOSH/MSHA or European Standard EN 149 approved respirator whenever workplace
conditions warrant respirator use.
Section 9 - Physical and Chemical Properties
Physical State: Liquid
Color: Orange
Odor: Alcohol odor
pH: Not available
Vapor Pressure: 59 mm Hg @ 25癈
Vapor Density: 1.59
Evaporation Rate: Not available
Viscosity: 1.200 cP @ 20癈
Boiling Point: 78癈
Freezing/Melting Point: -114癈
Decomposition Temperature: Not available
Solubility in water: Soluble
Specific Gravity/Density: 0.790 @ 20癈
Molecular Formula: Not applicable
Molecular Weight: Not applicable
Section 10 - Stability and Reactivity
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, ignition sources, excess heat, strong oxidizing agents.
Incompatibilities with Other Materials:
Strong oxidizing agents, acids, alkali metals, ammonia, hydrazine, peroxides, sodium, acid
anhydrides, calcium hypochlorite, chromyl chloride, nitrosyl perchlorate, bromine pentafluoride,
perchloric acid, silver nitrate, mercuric nitrate, potassium tert-butoxide, magnesium perchlorate,
acid chlorides, platinum, uranium hexafluoride, silver oxide, iodine heptafluoride, acetyl bromide,
disulfuryl difluoride, tetrachlorosilane + water, acetyl chloride, permanganic acid, ruthenium (VIII)
oxide, uranyl perchlorate, potassium dioxide. .
Hazardous Decomposition Products:
Ammonia, nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen, chlorine.
Hazardous Polymerization:
Has not been reported.
-4-
Material Safety Data Sheet
Methyl Red TS
Section 11 - Toxicological Information
RTECS:
CAS# 493-52-7: unlisted.
CAS# 7732-18-5: ZC0110000
CAS# 64-17-5: KQ6300000
LD50/LC50:
CAS# 493-52-7:
Not available.
CAS# 64-17-5:
Draize test, rabbit, eye: 500 mg Severe
Draize test, rabbit, eye: 500 mg/24H Mild
Draize test, rabbit, skin: 20 mg/24H Moderate
Inhalation, rat: LC50 = 20000 ppm/10H
Oral, mouse: LD50 = 3450 mg/kg
Oral, rabbit: LD50 = 6300 mg/kg
Oral, rat: LD50 = 7060 mg/kg
Oral, rat: LD50 = 9000 mg/kg
CAS# 7732-18-5:
Oral, rat: LD50 = >90 mL/kg
Carcinogenicity:
CAS# 493-52-7: Not listed by ACGIH, IARC, NTP, or CA Prop 65.
CAS# 64-17-5: Not listed by ACGIH, IARC, NTP, or CA Prop 65.
CAS# 7732-18-5: Not listed by ACGIH, IARC, NTP, or CA Prop 65.
Epidemiology:
Ethanol has been shown to produce fetotoxicity in the embryo or fetus of laboratory animals.
Prenatal exposure to ethanol is associated with a distinct pattern of congenital malformations that
have collectively been termed the "fetal alcohol syndrome".
Teratogenicity:
Oral, Human - woman: TDLo = 41 g/kg (female 41 week(s) after conception) Effects on Newborn -
Apgar score (human only) and Effects on Newborn - other neonatal measures or effects and Effects
on Newborn - drug dependence.
Reproductive:
Intrauterine, Human - woman: TDLo = 200 mg/kg (female 5 day(s) pre-mating) Fertility - female
fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per #
females mated).
Mutagenicity:
DNA Inhibition: Human, Lymphocyte = 220 mmol/L.; Cytogenetic Analysis: Human, Lymphocyte
= 1160 gm/L.; Cytogenetic Analysis: Human, Fibroblast = 12000 ppm; Cytogenetic Analysis:
Human, Leukocyte = 1 pph/72H (Continuous); Sister Chromatid Exchange: Human, Lymphocyte =
500 ppm/72H (Continuous).
Neurotoxicity:
No information found.
Section 12 - Ecological Information
Ecotoxicity: Fish: Rainbow trout: LC50 = 12900-15300 mg/L; 96 Hr; Flow-through @ 24-24.3癈
Fish: Rainbow trout: LC50 = 11200 mg/L; 24 Hr; Fingerling (Unspecified) Bacteria:
-5-
Material Safety Data Sheet
Methyl Red TS
Phytobacterium phosphoreum: EC50 = 34900 mg/L; 5-30 min; Microtox test. When spilled on land
it is apt to volatilize, biodegrade, and leach into the ground water, but no data on the rates of these
processes could be found. Its fate in ground water is unknown. When released into water it will
volatilize and probably biodegrade. It would not be expected to adsorb to sediment or
bioconcentrate in fish.
Environmental: When released to the atmosphere, it will photodegrade in hours (polluted urban
atmosphere) to an estimated range of 4 to 6 days in less polluted areas. Rainout should be
significant.
Section 13 - Disposal Considerations
Dispose of in accordance with Federal, State, and local regulations.
Section 14 - Transport Information
US DOT
Shipping Name: Ethanol solution
Hazard Class: 3
UN Number: UN1170
Packing Group: II
Section 15 - Regulatory Information
US Federal
TSCA:
CAS# 493-52-7 is listed on the TSCA inventory.
CAS# 64-17-5 is listed on the TSCA inventory.
CAS# 7732-18-5 is listed on the TSCA inventory.
SARA Reportable Quantities (RQ):
None of the chemicals in this material have an RQ.
CERCLA/SARA Section 313:
None of the chemicals in this material are reportable under Section 313.
OSHA - Highly Hazardous:
None of the chemicals in this product are considered highly hazardous by OSHA.
US State
State Right to Know:
CAS# 493-52-7 is not present on state lists from California, Pennsylvania, Minnesota,
Massachusetts, Florida, or New Jersey.
CAS# 64-17-5 can be found on the following state right to know lists: California, New Jersey,
Pennsylvania, Minnesota, Massachusetts.
CAS# 7732-18-5 is not present on state lists from California, Pennsylvania, Minnesota,
Massachusetts, Florida, or New Jersey.
California Regulations:
WARNING: This product contains Ethyl alcohol, a chemical known to the state of California to
cause developmental reproductive toxicity.
-6-
Material Safety Data Sheet
Methyl Red TS
European/International Regulations
Canadian DSL/NDSL:
CAS# 493-52-7 is listed on Canada's DSL List.
CAS# 64-17-5 is listed on Canada's DSL List.
CAS# 7732-18-5 is listed on Canada's DSL List.
Canada Ingredient Disclosure List:
CAS# 493-52-7 is not listed on the Canadian Ingredient Disclosure List.
CAS# 64-17-5 is listed on the Canadian Ingredient Disclosure List.
CAS# 7732-18-5 is not listed on the Canadian Ingredient Disclosure List.
Section 16 - Other Information
MSDS Creation Date: March 17, 2008
Revision Date: None
Information in this MSDS is from available published sources and is believed to be accurate. No warranty, express or implied,
is made and LabChem Inc. assumes no liability resulting from the use of this MSDS. The user must determine suitability of this
information for his application.
-7-
|