MATERIAL SAFETY DATA SHEET
In Case of Emergency, Call
Syngenta Crop Protection, Inc.
1-800-888-8372
Post Office Box 18300
Greensboro, NC 27419
1. PRODUCT IDENTIFICATION
GRAMOXONE INTEON
Product Name: Product No.: A7813K
EPA Signal Word: Danger-Poison
Active Ingredient(%): Paraquat Dichloride (30.1%) CAS No.: 1910-42-5
Chemical Name: (1,1'-dimethyl-4,4'-bipyridinium dichloride)
Chemical Class: Herbicide
EPA Registration Number(s): 100-1217 Section(s) Revised: 14
2. HAZARDS IDENTIFICATION
Health and Environmental
Fatal if inhaled. May be fatal if swallowed. Harmful in contact with skin. Causes eye and skin irritation.
Hazardous Decomposition Products
Combustion products of dry material: Carbon dioxide, carbon monoxide, chlorine, hydrogen chloride, possible trace
amounts of phosgene, nitrogen oxides, ammonia, and other toxic and noxious fumes.
Physical Properties
Appearance: Bluish green to dark green liquid
Odor: Characteristic; strong
Unusual Fire, Explosion and Reactivity Hazards
Hydrolyzes in alkaline media. This product reacts with aluminum to produce hydrogen gas. Do not mix or store in
containers or systems made of aluminum or having aluminum fittings.
During a fire, irritating and possibly toxic gases may be generated by thermal decomposition or combustion.
3. COMPOSITION/INFORMATION ON INGREDIENTS
ACGIH
OSHA NTP/IARC/OSHA
Other
TLV
PEL Carcinogen
Material
Paraquat Emetic (0.13%) Not Established Not Established 0.02 mg/m?TWA *** No
Paraquat Dichloride (30.1%) 0.5 mg/m?TWA 0.1 mg/m?TWA 0.08 mg/m?TWA No
(respirable; skin; as (respirable); 0.5 mg/m? (respirable); 0.5
paraquat) TWA (total) mg/m?TWA (total)
***
*** Syngenta Occupational Exposure Limit (OEL)
Ingredients not precisely identified are proprietary or non-hazardous. Values are not product specifications.
Syngenta Hazard Category: E, S
4. FIRST AID MEASURES
Have the product container, label or Material Safety Data Sheet with you when calling Syngenta (800-888-8372), a poison
contol center or doctor, or going for treatment.
Product Name: GRAMOXONE INTEON Page: 1
SPEED IS ESSENTIAL. Immediate medical attention is required. If available, give an adsorbent such as
Ingestion:
activated charcoal, bentonite or Fuller's Earth.
Call a poison control center or doctor immediately for treatment advice.
Do not give anything by mouth to an unconscious person.
If in eyes: Hold eye open and rinse slowly and gently with water for 15-20 minutes. Remove contact lenses, if
Eye Contact:
present, after 5 minutes, then continue rinsing eye. Call Syngenta (800-888-8372), a poison control center or
doctor for treatment advice.
Skin Contact: If on skin or clothing: Take off contaminated clothing. Rinse skin immediately with plenty of water for 15-20
minutes. Call Syngenta (800-888-8372), a poison control center or doctor for treatment advice.
Move person to fresh air.
Inhalation:
The odor of this product is from the stenching agent, which has been added, not from the paraquat.
If person is not breathing, call 911 or an ambulance.
Call a poison control center or doctor for further treatment advice.
Notes to Physician
Refer to the booklet 'Paraquat Poisoning. A Practical Guide to Diagnosis, First Aid and Hospital Treatment'
(http://www.syngenta.com/pqmedguide/). Administer either activated charcoal (100 g for adults or 2 g/kgbody weight in
children) or Fuller's Earth (15% solution; 1 liter for adults or 15 ml/kg body weight in children). NOTE: The use of gastric
lavage without administration of an adsorbent has not shown any clinical benefit. Do not use supplemental oxygen. Eye
splashes from concentrated material should be treated by an eye specialist after initial treatment. With the possibility of late
onset corneal ulceration, it is advised that patients with paraquat eye injuries are reviewed by an eye specialist the day after
first presentation. Use treatment that is appropriate for chemical burns. Intact skin is an effective barrier to paraquat,
however, contact with irritated or cut skin or repeated contact with intact skin may result in poisoning.
Medical Condition Likely to be Aggravated by Exposure
None known.
5. FIRE FIGHTING MEASURES
Fire and Explosion
Flash Point (Test Method): Not Available
Flammable Limits (% in Air): Lower: Not Applicable Upper: Not Applicable
Autoignition Temperature: Not Available
Flammability: Does not flash
Unusual Fire, Explosion and Reactivity Hazards
Hydrolyzes in alkaline media. This product reacts with aluminum to produce hydrogen gas. Do not mix or store in
containers or systems made of aluminum or having aluminum fittings.
During a fire, irritating and possibly toxic gases may be generated by thermal decomposition or combustion.
In Case of Fire
Use dry chemical, foam or CO2 extinguishing media. Wear full protective clothing and self-contained breathing apparatus.
Evacuate nonessential personnel from the area to prevent human exposure to fire, smoke, fumes or products of combustion.
Prevent use of contaminated buildings, area, and equipment until decontaminated. Water runoff can cause environmental
damage. If water is used to fight fire, dike and collect runoff.
6. ACCIDENTAL RELEASE MEASURES
In Case of Spill or Leak
Untreated spilled material can dry to a highly irritating dust.
Control the spill at its source. Contain the spill to prevent from spreading or contaminating soil or from entering sewage and
drainage systems or any body of water. Clean up spills immediately, observing precautions outlined in Section 8. Cover
entire spill with absorbing material and place into compatible disposal container. Scrub area with hard water detergent (e.g.
commercial products such as Tide, Joy, Spic and Span). Pick up wash liquid with additional absorbent and place into
compatible disposal container. Once all material is cleaned up and placed in a disposal container, seal container and arrange
for disposition.
Product Name: GRAMOXONE INTEON Page: 2
7. HANDLING AND STORAGE
Store above 32癋 (0癈).
Store the material in a well-ventilated, secure area out of reach of children and domestic animals. Do not store food, beverages
or tobacco products in the storage area. Prevent eating, drinking, tobacco use, and cosmetic application in areas where there is a
potential for exposure to the material. Wash thoroughly with soap and water after handling.
8. EXPOSURE CONTROLS/PERSONAL PROTECTION
THE FOLLOWING RECOMMENDATIONS FOR EXPOSURE CONTROLS/PERSONAL PROTECTION ARE INTENDED FOR
THE MANUFACTURE, FORMULATION AND PACKAGING OF THIS PRODUCT.
FOR COMMERCIAL APPLICATIONS AND/OR ON-FARM APPLICATIONS CONSULT THE PRODUCT LABEL.
Store the material in a well-ventilated area out of the reach of children and domestic animals. Do not store
Ingestion:
food, beverages, or tobacco products in the storage area. Prevent eating, drinking, tobacco usage and
cosmetic application in areas where there is a potential for exposure to the material. Always wash thoroughly
after handling.
Eye Contact: Where eye contact is likely, use chemical splash goggles.
Skin Contact: This product is FIFRA regulated. Refer to product labeling for end-user personal protection requirements.
When handling or when exposure to concentrate is possible, wear: long-sleeved shirt and long pants,
waterproof gloves, shoes and socks, face shield and chemical-resistant apron. Remove any contaminated
clothing promptly. Syngenta conducted ASTM permeation tests using PVC gloves (0.2mm thickness) which
showed no breakthrough of the product after eight hours of testing.
Inhalation: A respirator is not normally required when handling this substance. Use effective engineering controls to
comply with occupational exposure limits.
In case of emergency spills, use a NIOSH approved respirator with any N, R, P or HE filter.
9. PHYSICAL AND CHEMICAL PROPERTIES
Appearance: Bluish green to dark green liquid
Odor: Characteristic; strong
Melting Point: Not Applicable
Boiling Point: Not Available
Specific Gravity/Density: 1.12 g/cm?@ 68癋 (20癈)
4 - 8 (10 g/l in deionized water)
pH:
Solubility in H2O
Paraquat Dichloride: 620g/l @ 68癋 (20癈)
Vapor Pressure
Paraquat Dichloride: 7.5 x 10(-8) mmHg @ 77癋 (25癈)
10. STABILITY AND REACTIVITY
Stability: Stable under normal use and storage conditions.
Hazardous Polymerization: Will not occur.
Conditions to Avoid: Store above 32癋 (0癈).
Stable in acidic and neutral solution. Decomposed by alkali and in the presence of
U.V. light. Compound inactivated by adsorption onto inert clay.
Materials to Avoid: Hydrolyzes in alkaline media. This product reacts with aluminum to produce
hydrogen gas. Do not mix or store in containers or systems made of aluminum or
having aluminum fittings.
Hazardous Decomposition Products: Combustion products of dry material: Carbon dioxide, carbon monoxide, chlorine,
hydrogen chloride, possible trace amounts of phosgene, nitrogen oxides, ammonia,
and other toxic and noxious fumes.
Product Name: GRAMOXONE INTEON Page: 3
11. TOXICOLOGICAL INFORMATION
Acute Toxicity/Irritation Studies (Finished Product)
Ingestion:
Oral (LD50 Rabbit) : 310 mg/kg body weight
Dermal:
Dermal (LD50 Rabbit) : > 2000 mg/kg body weight
Inhalation:
0.0006 mg/l air - 4 hours (data based on a
Inhalation (LC50 Rat) :
similar formulation)
Eye Contact: Mildly Irritating (Rabbit)
Skin Contact: Moderately Irritating (Rabbit)
Skin Sensitization: Not a Sensitizer (Guinea Pig)
Reproductive/Developmental Effects
Paraquat Dichloride: A 3-generation reproduction study showed no evidence of fertility or reproductive effects at doses
below that causing maternal toxicity. Reproductive NOEL was above 7.5 mg/kg/day, the highest dose level.
Chronic/Subchronic Toxicity Studies
Paraquat Dichloride: Rodent studies showed signs of irritation in 21-day dermal studies. In a 2.5 year chronic study, rats
showed evidence of cataracts, body weight reduction and lung effects (alveolar macrophage infiltration) at 75 ppm and
above. A 90-day dog diet study showed evidence of lung effects leading to alveolar collapse and death at 3 mg/kg/day.
Chronic pneumonitis was seen in a 1-year dog study at 0.93 mg/kg/day and above.
Carcinogenicity
Paraquat Dichloride: No evidence in the rat or mouse.
Other Toxicity Information
None
Toxicity of Other Components
Paraquat Emetic (0.13%)
Toxic if swallowed. Slightly irritating to skin and eyes. Inhalation of dust may cause nausea and vomiting.
Target Organs
Active Ingredients
Paraquat Dichloride: Lung, kidney
Inert Ingredients
Paraquat Emetic: Skin, eye, respiratory system
12. ECOLOGICAL INFORMATION
Ecotoxicity Effects
Paraquat Dichloride:
Fish (Bluegill Sunfish) 96-hour LC50 13 ppm
Invertebrate (Water Flea) Daphnia Magna 48-hour EC50 1.2 ppm
Bird (Bobwhite Quail) 8-day LD50 176 mg/kg
Green Algae 4-day EC50 0.32 ppm
Environmental Fate
Paraquat Dichloride:
The information presented here is for the active ingredient, paraquat dichloride.
Product Name: GRAMOXONE INTEON Page: 4
Low bioaccumulation potential. Persistent in soil. Not persistent in water. Immobile in soil. Sinks in water (after 24 h).
13. DISPOSAL CONSIDERATIONS
Disposal
Do not reuse product containers. Dispose of product containers, waste containers, and residues according to local, state, and
federal health and environmental regulations.
Characteristic Waste: Corrosive D002
Listed Waste: Not listed
14. TRANSPORT INFORMATION
DOT Classification
Ground Transport - NAFTA
Proper Shipping Name: Corrosive Liquid, N.O.S. (Paraquat)
Hazard Class or Division: Class 8
Identification Number: UN 1760
Packing Group: PG III
Air Transport - NAFTA
Proper Shipping Name: Corrosive Liquid, N.O.S. (Paraquat)
Hazard Class or Division: Class 8
Identification Number: UN 1760
Packing Group: PG III
Packing Instructions: Passenger: PI 818 - Max. inner package 2.5 liter; Single packages, 5 liter Max.
Cargo: PI 820 - 5 liter. Inner packages, 60 liter single packages
B/L Freight Classification
Herbicides, NOI
Comments
Water Transport - International
Proper Shipping Name: Corrosive Liquid, N.O.S. (Paraquat), Marine Pollutant
Hazard Class or Division: Class 8
Identification Number: UN 1760
Packing Group: PG III
IMDG EMS #: F-A, S-B
Air Transport - International
Proper Shipping Name: Corrosive Liquid, N.O.S. (Paraquat)
Hazard Class or Division: Class 8
Identification Number: UN 1760
Packing Group: PG III
Packing Instructions: Passenger: PI 818 - Max. inner package 2.5 liter; Single packages, 5 liter Max.
Cargo: PI 820 - 5 liter. Inner packages, 60 liter single packages
15. REGULATORY INFORMATION
EPCRA SARA Title III Classification
Acute Health Hazard
Section 311/312 Hazard Classes:
Chronic Health Hazard
Section 313 Toxic Chemicals: Paraquat Dichloride (30.1%) (CAS No. 1910-42-5)
California Proposition 65
Not Applicable
Product Name: GRAMOXONE INTEON Page: 5
CERCLA/SARA 302 Reportable Quantity (RQ)
Report product spills > 5 gal. (based on paraquat dichloride [RQ = 10 lbs.] content in the formulation)
RCRA Hazardous Waste Classification (40 CFR 261)
Corrosive D002
TSCA Status
Exempt from TSCA, subject to FIFRA
16. OTHER INFORMATION
HMIS Hazard Ratings 0 Minimal
NFPA Hazard Ratings
1 Slight
Health: 3
Health: 4
2 Moderate
Flammability: 0
Flammability: 0
3 Serious
Reactivity: 0
Instability: 0
4 Extreme
For non-emergency questions about this product call:
1-800-334-9481
Original Issued Date: 2/18/2005
Revision Date: Replaces: 4/28/2009
6/30/2009
The information and recommendations contained herein are based upon data believed to be correct.
However, no guarantee or warranty of any kind, expressed or implied, is made with respect to the
information contained herein.
End of MSDS
Product Name: GRAMOXONE INTEON Page: 6
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