Safety Data Sheet
Revision date: 07-October-2003
replaces all previous editions
GRAMOXONE 100
1. IDENTIFICATION OF THE SUBSTANCE / PREPARATION AND COMPANY OR
UNDERTAKING
Identification of the Substance or Preparation
Tradename GRAMOXONE 100
Design Code YF 7697 A / A-3879D
AGI Code 1000185
Company Identification
Company Syngenta Crop Protection UK Ltd
Whittlesford, CAMBRIDGE, CB2 4QT
Phone (01223) 833621
Fax (01223) 493700
Website www.syngenta-crop.co.uk
Emergency Phone +44 (0) 1484 538444 (24h)
2. COMPOSITION / INFORMATION ON INGREDIENTS
Chemical characteristic
Formulation type An aqueous solution containing emetic, stench, surfactants and dye.
Use A bipyridyl contact herbicide.
EC-No. : 217-615-7 Paraquat dichloride
EC-No. : 269-929-9 Pyridine Bases
EC-No. : 248-383-5 Paraquat Emetic (aminopropyltriazolopyrimidone)
CAS-No. Hazardous ingredients Concentration Hazard Risk phrases
symbols (R)
1910-42-5 Paraquat dichloride 200 g/l as T+, N 24/25, 26,
(Classification according to paraquat ion 36/37/38,
Directive 67/548/EEC) 48/25, 50/53
68391-11-7 Pyridine Bases 10 g/l Xn 10, 20/21/22
27277-00-5 Paraquat Emetic < 10 g/l T 25
(aminopropyltriazolopyrimidone)
68412-54-4 Alkylphenol Ethoxylate < 100 g/l Xn 22, 36/38, 53
3. HAZARDS IDENTIFICATION
DO NOT PUT IN A FOOD OR DRINKS CONTAINER.
Harmful in contact with skin and if swallowed. Irritating to eyes, respiratory system and skin. Toxic:
danger of serious damage to health by prolonged exposure if swallowed. Corrosive.
Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
GRAMOXONE 100 Safety Data Sheet Page 1 of 6
4. FIRST AID MEASURES
OBTAIN IMMEDIATE MEDICAL ATTENTION. SPEED IS ESSENTIAL.
Refer to the booklet 'Paraquat Poisoning. A Practical Guide to Diagnosis, First
Aid and Hospital Treatment'
For further advice on treatment, contact Syngenta 24 hour emergency number 0044 (0) 1484 538444
or the nearest Poisons Information Centre.
Eye contact: Immediately irrigate with eyewash solution or clean water, holding the eyelids apart,
for at least 15 minutes. Obtain immediate medical attention.
Skin contact: Take off immediately all contaminated clothing. Wash skin immediately with water,
followed by soap and water. Such action is essential to minimise contact with skin.
Contaminated clothing should be laundered before re-issue. Obtain medical
attention.
Inhalation: Remove patient from exposure, keep warm and at rest. Obtain medical attention.
Ingestion: OBTAIN IMMEDIATE MEDICAL ATTENTION. SPEED IS ESSENTIAL.
Immediately transfer patient to nearest hospital or medical centre, warning by telephone of the
estimated arrival time so that the start of treatment is not delayed. Induce vomiting, if this has not
already occurred by tickling the back of the throat with a clean, blunt instrument (e.g. spoon handle).
Medical advice
HOSPITAL TREATMENT: Refer to the booklet 'Paraquat Poisoning. A Practical Guide to Diagnosis,
First Aid and Hospital Treatment'. Wash out stomach and test urine and gastric aspirate (if clear) for
presence of paraquat. Give up to 1 litre of 15% aqueous suspension of Fuller's Earth orally or via
gastric tube, together with a suitable purgative (200ml of a aqueous solution of Mannitol). Repeat
administration of absorbent plus purgative until absorbent is seen in the stools. This should normally
take between 4 and 6 hours after the start of treatment. Do not use supplemental oxygen.
With the possibility of late onset conjunctival ulceration it is advised that patients with paraquat eye
injuries are reviewed the day after first presentation. At the review, consideration should be given to
treating the eyes with a local antibiotic preparation to prevent secondary infection. Local treatment
with a suitable steroid will aid resolution of granulation tissue. Corneal oedema, which may persist
for up to 3-4 weeks, may cause blurring of vision
5. FIRE FIGHTING MEASURES
Keep fire exposed containers cool by spraying with water.
Extinguishing media: For small fires, use foam, carbon dioxide or dry powder extinguishant. For
large fires, use foam or water-fog; avoid use of water jet. Contain run-off water with, for example,
temporary earth barriers.
Protective Equipment: A self contained breathing apparatus and suitable protective clothing
should be worn in fire conditions.
6. ACCIDENTAL RELEASE MEASURES
Personal precautions: Ensure suitable personal protection during removal of spillages. This
means wearing eye protection, chemically resistant gloves, boots and coveralls.
Clean up methods: Adsorb spillages onto sand, earth or any suitable adsorbent material. Transfer
to a container for disposal. Wash the spillage area with water. Washings must be prevented from
entering surface water drains.
Spillages or uncontrolled discharges into water courses must be alerted to the appropriate regulatory
body.
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7. HANDLING AND STORAGE
Handling
Read the label before use.
Avoid contact with skin and eyes. Do not breathe spray mist. When using do not eat, drink or smoke.
Wash face and hands before eating, drinking or smoking.
Storage
Keep in original containers, tightly closed and locked up. Keep out of reach of children. Keep away
from food, drink and animal feeding stuffs. Protect from frost.
Storage Life: Physically and chemically stable for at least 2 years when stored in the original
unopened sales container at ambient temperatures.
8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Personal protection
When using this product refer to the label for details. In all other cases, use the following Personal
Protective Equipment:
Where suitable engineering controls are not fitted or are inadequate, wear suitable protective
equipment. When selecting personal protective equipment, users should consult their supplier to
confirm that the equipment is suitable.
Respiratory protection: Wear suitable respiratory protective equipment if exposure to levels above
the occupational exposure limit is likely. Respiratory protective equipment should conform to the
appropriate EN standard.
Eye protection: Wear suitable eye/face protection conforming to EN 166.
Hand protection: Wear suitable gloves conforming to EN 374.
Body protection: Wear suitable protective clothing.
Occupational exposure limits
Syngenta standard Occupational exposure limits:
Paraquat Emetic; 8 hr TWA 0.02 mg/m?br>
Pyridine Bases Syngenta; 8 hr TWA 1 ppm, 5 mg/m?Sk: Can be absorbed through skin
HSE, EH40/2002 Occupation exposure limits:
Paraquat dichloride (Respirable Dust); 8 hr TWA 0.08 mg/m?br>
Not applicable to field use.
9. PHYSICAL AND CHEMICAL PROPERTIES
Form : Liquid.
Colour : Dark blue / green.
Odour : Characteristic of pyridine bases.
Boiling point : Approx 100 癈, aqueous solution.
Melting point : Not available.
Flash point : Does not flash.
Autoignition temperature : Not available.
Explosive properties : Not applicable.
Vapour pressure : Not available.
Solubility : Soluble in/with water.
pH-value (quant.) : 6.5 .. 7.5
Partition coeff. : Not applicable.
Oxidizing properties : Not applicable.
GRAMOXONE 100 Safety Data Sheet Page 3 of 6
10. STABILITY AND REACTIVITY
Hazardous reactions, (materials to avoid): Paraquat is highly corrosive to most metals e.g.,
aluminium, zinc, iron.
Hazardous decomposition products: Combustion or thermal decomposition will evolve toxic and
irritant vapours.
11. TOXICOLOGICAL INFORMATION
Acute Toxicity (Lethal Doses)
LD50 Oral male rats: 707 mg formulation/kg
LD50 Oral female rats: 612 mg formulation/kg; Harmful if swallowed.
LD50 Dermal male rats: 590 mg formulation/kg
LD50 Dermal female rats: 735 mg formulation/kg; Harmful in contact with skin.
Inhalation: Nose bleeding and soreness of the throat may result from spray mist or dust trapped on
the nasal mucosa. If this occurs review spraying and handling technique.
Acute Toxicity (Irritation, Sensitisation, etc.)
Skin Irritation : Moderate/severe irritant to rabbit skin.
Eye Irritation : Moderate irritant to rabbit eyes. May cause eye irritation in man.
Skin Sensitisation瑽uehler : It is not a skin sensitiser in animal tests.
Respiratory Irritation : High concentrations of mist may be irritant to the respiratory tract.
Chronic Toxicological Effects / Long Term Exposure.
Ocular effects (cataracts) have been reported following long term oral exposure of laboratory
animals.
12. ECOLOGICAL INFORMATION
Environmental Fate and Distribution
Liquid with low volatility. Information applies to Paraquat ion: The substance is soluble in water. The
substance does not leach. The substance does not bioaccumulate. Paraquat is rapidly adsorbed
and de-activated by soil.
Ecotoxicity
Harmful if drunk by livestock
Toxicity to fish : LC50 96 hours Rainbow trout: 8.3 mg/l
Toxicity to daphnia : EC50 48 hours Daphnia magna: 6 mg/l
Toxicity to algae : EbC50 green algae: 0.11 mg/l
: ErC50 green algae: 0.34 mg/l
Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
13. DISPOSAL CONSIDERATIONS
Do not contaminate ponds, waterways or ditches with chemical or used containers. Surplus material
must be disposed of as detailed in the 'Guidelines for the avoidance, limitation and disposal of
pesticide waste on the farm' GCPF, 1987. Empty containers should be washed and discarded.
Empty containers should not be used for other purposes. Disposal should be in accordance with
local, state or national legislation.
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14. TRANSPORT INFORMATION
Road transport ADR/RID
UN No. : UN2922
UN Packaging Group : III
Class -primary : 8 Corrosive
-subsidiary : 6.1 Toxic Substance
Proper shipping name : CORROSIVE LIQUID, TOXIC, N.O.S., (CONTAINS PARAQUAT
DICHLORIDE 28%)
Maritime transport IMDG
UN No. : UN2922
UN Packaging Group : III
Class -primary : 8 Corrosive
-subsidiary : 6.1 Toxic Substance
Proper shipping name : CORROSIVE LIQUID, TOXIC, N.O.S., (contains paraquat dichloride
28%)
Marine pollutant : No
Air transport ICAO/IATA
UN/ID No. : UN2922
UN Packaging Group : III
Class -primary : 8 Corrosive
-subsidiary : 6.1 Toxic Substance
Proper shipping name : CORROSIVE LIQUID, TOXIC, N.O.S., (contains paraquat dichloride
28%)
15. REGULATORY INFORMATION
Hazard symbols / T TOXIC
Classifications: N DANGEROUS FOR THE ENVIRONMENT
21/22 Harmful in contact with skin and if swallowed.
Risk phrases (R):
36/37/38 Irritating to eyes, respiratory system and skin.
48/25 Toxic: danger of serious damage to health by prolonged
exposure if swallowed.
50/53 Very toxic to aquatic organisms, may cause long-term
adverse effects in the aquatic environment.
2 Keep out of the reach of children.
Safety phrases (S):
13 Keep away from food, drink and animal feeding stuffs.
20/21 When using, do not eat, drink or smoke.
35 This material and its container must be disposed of in a safe
way.
36/37 Wear suitable protective clothing and gloves.
45 In case of accident or if you feel unwell, seek medical advice
immediately (show the label where possible).
57 Use appropriate containment to avoid environmental
contamination.
To avoid risks to man and the environment, comply with the
Special label:
instructions for use.
Users should ensure that they comply with any relevant local, state or national legislation.
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16. OTHER INFORMATION
Always read the label. Use pesticides safely.
Based upon SDS version 8, release date 18/12/02 with DPD update. Significant revision to sections
2,3 & 15.
Approval number; MAPP 10526.
This data sheet was prepared in accordance with Directive 91/155/EEC (93/112/EC, 2001/58/EC)
The information on this sheet is not a specification, it does not guarantee specific properties. The
information is intended to provide general guidance as to health and safety based upon our
knowledge of the handling, storage and use of the product. It is not applicable to unusual or
non-standard uses of the product nor where instructions or recommendations are not followed.
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