BIO BASIC INC.
160 TORBAY ROAD, MARKHAM ONTARIO L3R 1G6 CANADA
TEL: (905) 474 4493, (800) 313 7224 FAX: (905) 474 5794
MATERIAL SAFETY DATA SHEET
REQUIRED UNDER SAFETY AND HEALTH REGULATION FOR SHIP REPAIRING
MANUFACTURER'S NAME: BIO BASIC INC.
TEL: (905) 474 4493
FAX: (905) 474 5794
FOR CHEMICAL EMERGENCY: (416) 995 9730
ADDRESS: 160 TORBAY ROAD, MARKHAM ONTARIO L3R 1G6 CANADA
DATE PREPARED: JULY 26, 2007
SECTION 1 - PRODUCT AND COMPANY INFORMATION
PRODUCT NAME BISPHENOL A, 99+%
PRODUCT NUMBER BB0237
SECTION 2 - COMPOSITION/INFORMATION ON INGREDIENT
SUBSTANCE NAME CAS # SARA 313
4,4'-ISOPROPYLIDENEDIPHENOL 80-05-7 YES
FORMULA C15H16O2
SYNONYMS BISFEROL A (CZECH) *
2,2-BIS-4'-HYDROXYFENYLPROPAN (CZECH) *
BIS(4-HYDROXYPHENYL) DIMETHYLMETHANE *
BIS(4-HYDROXYPHENYL)PROPANE *
2,2-BIS(P-HYDROXYPHENYL)PROPANE *
2,2-BIS(4-HYDROXYPHENYL)PROPANE * BISPHENOL *
BISPHENOL A (OSHA) * 4,4'-BISPHENOL A * DIAN *
P,P'-DIHYDROXYDIPHENYLDIMETHYLMETHANE *
4,4'-DIHYDROXYDIPHENYLDIMETHYLMETHANE *
P,P'-DIHYDROXYDIPHENYLPROPANE *
2,2-(4,4'-DIHYDROXYDIPHENYL)PROPANE *
4,4'-DIHYDROXYDIPHENYLPROPANE *
4,4'-DIHYDROXYDIPHENYL-2,2-PROPANE *
4,4'-DIHYDROXY-2,2-DIPHENYLPROPANE *
DIMETHYLMETHYLENE-P,P'-DIPHENOL *
BETA-DI-P-HYDROXYPHENYLPROPANE *
2,2-DI(4-HYDROXYPHENYL)PROPANE * DIMETHYL
BIS(P-HYDROXYPHENYL)METHANE * DIPHENYLOLPROPANE *
2,2-DI(4-PHENYLOL)PROPANE *
P,P'-ISOPROPYLIDENEBISPHENOL *
4,4'-ISOPROPYLIDENEBISPHENOL *
P,P'-ISOPROPYLIDENEDIPHENOL * NCI-C50635 *
PHENOL, 4,4'-DIMETHYLMETHYLENEDI- * PROPANE,
2,2-BIS(P-HYDROXYPHENYL)- * UCAR BISPHENOL A
SECTION 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
HARMFUL.
IRRITATING TO RESPIRATORY SYSTEM. RISK OF SERIOUS DAMAGE TO EYES.
MAY CAUSE SENSITIZATION BY SKIN CONTACT. POSSIBLE RISK OF IMPAIRED
FERTILITY.
TARGET ORGAN(S): LIVER. BONE MARROW.
HMIS RATING
HEALTH: 3*
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FLAMMABILITY: 0
REACTIVITY: 0
NFPA RATING
HEALTH: 3
FLAMMABILITY: 0
REACTIVITY: 0
*ADDITIONAL CHRONIC HAZARDS PRESENT.
FOR ADDITIONAL INFORMATION ON TOXICITY, PLEASE REFER TO SECTION 11.
SECTION 4 - FIRST AID MEASURES
ORAL EXPOSURE
IF SWALLOWED, WASH OUT MOUTH WITH WATER PROVIDED PERSON IS
CONSCIOUS. CALL A PHYSICIAN.
INHALATION EXPOSURE
IF INHALED, REMOVE TO FRESH AIR. IF BREATHING BECOMES DIFFICULT,
CALL A PHYSICIAN.
DERMAL EXPOSURE
IN CASE OF SKIN CONTACT, FLUSH WITH COPIOUS AMOUNTS OF WATER FOR
AT LEAST 15 MINUTES. REMOVE CONTAMINATED CLOTHING AND SHOES.
CALL A PHYSICIAN.
EYE EXPOSURE
IN CASE OF CONTACT WITH EYES, FLUSH WITH COPIOUS AMOUNTS OF
WATER FOR AT LEAST 15 MINUTES. ASSURE ADEQUATE FLUSHING BY
SEPARATING THE EYELIDS WITH FINGERS. CALL A PHYSICIAN.
SECTION 5 - FIRE FIGHTING MEASURES
EXPLOSION DATA
DUST POTENTIAL: DUST AND FUMES MAY BE A FIRE AND EXPLOSION
HAZARD WHEN EXPOSED TO HIGH TEMPERATURES OR IGNITION SOURCES.
PARTICLE SIZE AND DISPERSION IN AIR DETERMINE REACTIVITY.
FLASH POINT
N/A
AUTOIGNITION TEMP
N/A
FLAMMABILITY
N/A
EXTINGUISHING MEDIA
SUITABLE: CARBON DIOXIDE, DRY CHEMICAL POWDER, OR APPROPRIATE
FOAM.
FIREFIGHTING
PROTECTIVE EQUIPMENT: WEAR SELF-CONTAINED BREATHING APPARATUS
AND PROTECTIVE CLOTHING TO PREVENT CONTACT WITH SKIN AND EYES.
SPECIFIC HAZARD(S): EMITS TOXIC FUMES UNDER FIRE CONDITIONS.
SECTION 6 - ACCIDENTAL RELEASE MEASURES
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
WEAR RESPIRATOR, CHEMICAL SAFETY GOGGLES, RUBBER BOOTS, AND
HEAVY RUBBER GLOVES.
METHODS FOR CLEANING UP
SWEEP UP, PLACE IN A BAG AND HOLD FOR WASTE DISPOSAL. AVOID
RAISING DUST. VENTILATE AREA AND WASH SPILL SITE AFTER MATERIAL
PICKUP IS COMPLETE.
SECTION 7 - HANDLING AND STORAGE
HANDLING
USER EXPOSURE: AVOID BREATHING DUST. AVOID CONTACT WITH EYES,
SKIN, AND CLOTHING. AVOID PROLONGED OR REPEATED EXPOSURE.
STORAGE
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SUITABLE: KEEP TIGHTLY CLOSED.
SECTION 8 - EXPOSURE CONTROLS / PPE
ENGINEERING CONTROLS
MECHANICAL EXHAUST REQUIRED.
PERSONAL PROTECTIVE EQUIPMENT
RESPIRATORY: USE RESPIRATORS AND COMPONENTS TESTED AND APPROVED
UNDER APPROPRIATE GOVERNMENT STANDARDS SUCH AS NIOSH (US) OR CEN
(EU). WHERE RISK ASSESSMENT SHOWS AIR-PURIFYING RESPIRATORS ARE
APPROPRIATE USE A DUST MASK TYPE N95 (US) OR TYPE P1 (EN 143)
RESPIRATOR.
OTHER: WEAR APPROPRIATE GOVERNMENT APPROVED RESPIRATOR,
CHEMICAL-RESISTANT GLOVES, SAFETY GOGGLES, OTHER PROTECTIVE
CLOTHING.
GENERAL HYGIENE MEASURES
WASH THOROUGHLY AFTER HANDLING. WASH CONTAMINATED CLOTHING BEFORE
REUSE.
SECTION 9 - PHYSICAL/CHEMICAL PROPERTIES
APPEARANCE PHYSICAL STATE: SOLID
COLOR: VERY FAINTLY BEIGE
FORM: CRYSTALLINE
PROPERTY VALUE AT TEMPERATURE OR PRESSURE
MOLECULAR WEIGHT 228.29 AMU
PH N/A
BP/BP RANGE 220 ?4 MMHG
C
MP/MP RANGE 153 ?C
FREEZING POINT N/A
VAPOR PRESSURE N/A
VAPOR DENSITY N/A
SATURATED VAPOR CONC. N/A
SG/DENSITY N/A
BULK DENSITY N/A
ODOR THRESHOLD N/A
VOLATILE% N/A
VOC CONTENT N/A
WATER CONTENT N/A
SOLVENT CONTENT N/A
EVAPORATION RATE N/A
VISCOSITY N/A
SURFACE TENSION N/A
PARTITION COEFFICIENT LOG KOW: 3.32
DECOMPOSITION TEMP. N/A
FLASH POINT N/A
EXPLOSION LIMITS N/A
FLAMMABILITY N/A
AUTOIGNITION TEMP N/A
REFRACTIVE INDEX N/A
OPTICAL ROTATION N/A
MISCELLANEOUS DATA N/A
SOLUBILITY N/A
N/A = NOT AVAILABLE
SECTION 10 - STABILITY AND REACTIVITY
STABILITY
STABLE: STABLE.
MATERIALS TO AVOID: STRONG BASES, STRONG OXIDIZING AGENTS.
HAZARDOUS DECOMPOSITION PRODUCTS
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HAZARDOUS DECOMPOSITION PRODUCTS: CARBON MONOXIDE, CARBON DIOXIDE.
HAZARDOUS POLYMERIZATION
HAZARDOUS POLYMERIZATION: WILL NOT OCCUR
SECTION 11 - TOXICOLOGICAL INFORMATION
ROUTE OF EXPOSURE
SKIN CONTACT: MAY CAUSE SKIN IRRITATION.
SKIN ABSORPTION: MAY BE HARMFUL IF ABSORBED THROUGH THE SKIN.
EYE CONTACT: CAUSES SEVERE EYE IRRITATION.
INHALATION: MATERIAL MAY BE IRRITATING TO MUCOUS MEMBRANES AND
UPPER RESPIRATORY TRACT. MAY BE HARMFUL IF INHALED.
INGESTION: MAY BE HARMFUL IF SWALLOWED.
SENSITIZATION
SKIN: MAY CAUSE ALLERGIC SKIN REACTION.
TARGET ORGAN(S) OR SYSTEM(S)
LIVER. BONE MARROW.
SIGNS AND SYMPTOMS OF EXPOSURE
TO THE BEST OF OUR KNOWLEDGE, THE CHEMICAL, PHYSICAL, AND
TOXICOLOGICAL PROPERTIES HAVE NOT BEEN THOROUGHLY INVESTIGATED.
TOXICITY DATA
ORAL
RAT
5,000 MG/KG
LD50
SKIN
RABBIT
3,000 MG/KG
LD50
SKIN
RABBIT
6,400 MG/KG
LD50
ORAL
RAT
3250 MG/KG
LD50
ORAL
MOUSE
2400 MG/KG
LD50
REMARKS: BEHAVIORAL:CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD.
AUTONOMIC NERVOUS SYSTEM:OTHER (DIRECT) PARASYMPATHOMIMETIC.
BEHAVIORAL:ATAXIA.
INTRAPERITONEAL
MOUSE
150 MG/KG
LD50
ORAL
RABBIT
2230 MG/KG
LD50
SKIN
RABBIT
3 ML/KG
LD50
ORAL
GUINEA PIG
4000 MG/KG
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LD50
REMARKS: AUTONOMIC NERVOUS SYSTEM:OTHER (DIRECT)
PARASYMPATHOMIMETIC. BEHAVIORAL:CONVULSIONS OR EFFECT ON SEIZURE
THRESHOLD. BEHAVIORAL:ATAXIA.
ORAL
MAMMAL
6500 MG/KG
LD50
IRRITATION DATA
SKIN
RABBIT
REMARKS: MILD IRRITATION EFFECT
SKIN
RABBIT
250 MG
REMARKS: OPEN IRRITATION TEST
SKIN
RABBIT
500 MG
24H
REMARKS: MILD IRRITATION EFFECT
EYES
RABBIT
0.25 MG
24H
REMARKS: SEVERE IRRITATION EFFECT
CHRONIC EXPOSURE - CARCINOGEN
RESULT: THIS PRODUCT IS OR CONTAINS A COMPONENT THAT IS PROBABLY
NOT CARCINOGENIC BASED ON ITS IARC, ACGIH, NTP, OR EPA
CLASSIFICATION.
NTP CARCINOGEN LIST
RATING: INADEQUATE STUDIES
SPECIES: MOUSE/RAT
ROUTE: FEED
CHRONIC EXPOSURE - TERATOGEN
SPECIES: RAT
DOSE: 10 GM/KG
ROUTE OF APPLICATION: ORAL
EXPOSURE TIME: (6-15D PREG)
RESULT: EFFECTS ON EMBRYO OR FETUS: FETOTOXICITY (EXCEPT DEATH,
E.G., STUNTED FETUS).
SPECIES: RAT
DOSE: 1275 MG/KG
ROUTE OF APPLICATION: INTRAPERITONEAL
EXPOSURE TIME: (1-15D PREG)
RESULT: SPECIFIC DEVELOPMENTAL ABNORMALITIES: MUSCULOSKELETAL
SYSTEM.
SPECIES: RAT
DOSE: 1275 MG/KG
ROUTE OF APPLICATION: INTRAPERITONEAL
EXPOSURE TIME: (1-15D PREG)
RESULT: EFFECTS ON EMBRYO OR FETUS: FETOTOXICITY (EXCEPT DEATH,
E.G., STUNTED FETUS).
SPECIES: MOUSE
DOSE: 900 MG/KG
ROUTE OF APPLICATION: SUBCUTANEOUS
EXPOSURE TIME: (11-19D PREG)
RESULT: SPECIFIC DEVELOPMENTAL ABNORMALITIES: UROGENITAL SYSTEM.
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CHRONIC EXPOSURE - MUTAGEN
SPECIES: RAT
DOSE: 200 UMOL/L
CELL TYPE: LIVER
MUTATION TEST: DNA DAMAGE
SPECIES: RAT
ROUTE: INTRAPERITONEAL
DOSE: 200 MG/KG
MUTATION TEST: DNA
SPECIES: RAT
ROUTE: ORAL
DOSE: 800 MG/KG
EXPOSURE TIME: 4D
MUTATION TEST: DNA
SPECIES: HAMSTER
DOSE: 200 UMOL/L
CELL TYPE: LUNG
MUTATION TEST: MICRONUCLEUS TEST
SPECIES: HAMSTER
DOSE: 400 UMOL/L
CELL TYPE: OVARY
MUTATION TEST: DNA INHIBITION
SPECIES: HAMSTER
DOSE: 400 UMOL/L
CELL TYPE: OVARY
MUTATION TEST: CYTOGENETIC ANALYSIS
CHRONIC EXPOSURE - REPRODUCTIVE HAZARD
RESULT: OVEREXPOSURE MAY CAUSE REPRODUCTIVE DISORDER(S) BASED ON
TESTS WITH LABORATORY ANIMALS.
SPECIES: RAT
DOSE: 15 GM/KG
ROUTE OF APPLICATION: ORAL
EXPOSURE TIME: (6-15D PREG)
RESULT: EFFECTS ON FERTILITY: POST-IMPLANTATION MORTALITY (E.G.,
DEAD AND/OR RESORBED IMPLANTS PER TOTAL NUMBER OF IMPLANTS).
SPECIES: RAT
DOSE: 2120 UG/KG
ROUTE OF APPLICATION: ORAL
EXPOSURE TIME: (10D PRE-21D POST)
RESULT: EFFECTS ON NEWBORN: BEHAVIORAL.
SPECIES: RAT
DOSE: 6400 UG/KG
ROUTE OF APPLICATION: ORAL
EXPOSURE TIME: (13-22D PREG/1-6D POST)
RESULT: EFFECTS ON NEWBORN: BEHAVIORAL.
SPECIES: RAT
DOSE: 1875 MG/KG
ROUTE OF APPLICATION: INTRAPERITONEAL
EXPOSURE TIME: (1-15D PREG)
RESULT: EFFECTS ON FERTILITY: LITTER SIZE (E.G.; # FETUSES PER
LITTER; MEASURED BEFORE BIRTH). EFFECTS ON FERTILITY:
PRE-IMPLANTATION MORTALITY (E.G., REDUCTION IN NUMBER OF
IMPLANTS PER FEMALE; TOTAL NUMBER OF IMPLANTS PER CORPORA LUTEA).
SPECIES: RAT
DOSE: 1275 MG/KG
ROUTE OF APPLICATION: INTRAPERITONEAL
EXPOSURE TIME: (1-15D PREG)
RESULT: EFFECTS ON FERTILITY: LITTER SIZE (E.G.; # FETUSES PER
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LITTER; MEASURED BEFORE BIRTH). EFFECTS ON EMBRYO OR FETUS:
FETOTOXICITY (EXCEPT DEATH, E.G., STUNTED FETUS). SPECIFIC
DEVELOPMENTAL ABNORMALITIES: CENTRAL NERVOUS SYSTEM.
SPECIES: RAT
DOSE: 1875 MG/KG
ROUTE OF APPLICATION: INTRAPERITONEAL
EXPOSURE TIME: (1-15D PREG)
RESULT: EFFECTS ON FERTILITY: POST-IMPLANTATION MORTALITY (E.G.,
DEAD AND/OR RESORBED IMPLANTS PER TOTAL NUMBER OF IMPLANTS).
SPECIFIC DEVELOPMENTAL ABNORMALITIES: GASTROINTESTINAL SYSTEM.
SPECIES: MOUSE
DOSE: 12500 MG/KG
ROUTE OF APPLICATION: ORAL
EXPOSURE TIME: (6-15D PREG)
RESULT: EFFECTS ON FERTILITY: POST-IMPLANTATION MORTALITY (E.G.,
DEAD AND/OR RESORBED IMPLANTS PER TOTAL NUMBER OF IMPLANTS).
EFFECTS ON EMBRYO OR FETUS: FETOTOXICITY (EXCEPT DEATH, E.G.,
STUNTED FETUS). EFFECTS ON EMBRYO OR FETUS: FETAL DEATH.
SPECIES: MOUSE
DOSE: 7500 MG/KG
ROUTE OF APPLICATION: ORAL
EXPOSURE TIME: (6-15D PREG)
RESULT: EFFECTS ON FERTILITY: PRE-IMPLANTATION MORTALITY (E.G.,
REDUCTION IN NUMBER OF IMPLANTS PER FEMALE; TOTAL NUMBER OF
IMPLANTS PER CORPORA LUTEA).
SPECIES: MOUSE
DOSE: 12500 MG/KG
ROUTE OF APPLICATION: ORAL
EXPOSURE TIME: (6-15D PREG)
RESULT: MATERNAL EFFECTS: UTERUS, CERVIX, VAGINA.
SECTION 12 - ECOLOGICAL INFORMATION
ACCUMULATION
BIOACCUMULATION POTENTIAL: INDICATION OF
BIOACCUMULATION.
ACUTE ECOTOXICITY TESTS
TEST TYPE: LC50 FISH
SPECIES: PIMEPHALES PROMELAS (FATHEAD MINNOW)
TIME: 96 H
VALUE: 4.6 MG/L
TEST TYPE: EC50 DAPHNIA
SPECIES: DAPHNIA MAGNA
TIME: 48 H
VALUE: 3.9 MG/L
TEST TYPE: IC50 ALGAE
SPECIES: SELENASTRUM CAPRICORNUTUM RESP.
TIME: 96 H
VALUE: 2.73 MG/L
SECTION 13 - DISPOSAL CONSIDERATIONS
APPROPRIATE METHOD OF DISPOSAL OF SUBSTANCE OR PREPARATION
CONTACT A LICENSED PROFESSIONAL WASTE DISPOSAL SERVICE TO DISPOSE
OF THIS MATERIAL. DISSOLVE OR MIX THE MATERIAL WITH A COMBUSTIBLE
SOLVENT AND BURN IN A CHEMICAL INCINERATOR EQUIPPED WITH AN
AFTERBURNER AND SCRUBBER. OBSERVE ALL FEDERAL, STATE, AND LOCAL
ENVIRONMENTAL REGULATIONS.
SECTION 14 - TRANSPORT INFORMATION
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DOT
PROPER SHIPPING NAME: NONE
NON-HAZARDOUS FOR TRANSPORT: THIS SUBSTANCE IS
CONSIDERED TO BE NON-HAZARDOUS FOR TRANSPORT.
IATA
NON-HAZARDOUS FOR AIR TRANSPORT: NON-HAZARDOUS FOR AIR
TRANSPORT.
SECTION 15 - REGULATORY INFORMATION
EU DIRECTIVES CLASSIFICATION
SYMBOL OF DANGER: XN
INDICATION OF DANGER: HARMFUL.
R: 37-41-43-62
RISK STATEMENTS: IRRITATING TO RESPIRATORY SYSTEM. RISK OF
SERIOUS DAMAGE TO EYES. MAY CAUSE SENSITIZATION BY SKIN CONTACT.
POSSIBLE RISK OF IMPAIRED FERTILITY.
S: 26-36/37/39-45
SAFETY STATEMENTS: IN CASE OF CONTACT WITH EYES, RINSE
IMMEDIATELY WITH PLENTY OF WATER AND SEEK MEDICAL ADVICE. WEAR
SUITABLE PROTECTIVE CLOTHING, GLOVES, AND EYE/FACE PROTECTION.
IN CASE OF ACCIDENT OR IF YOU FEEL UNWELL, SEEK MEDICAL ADVICE
IMMEDIATELY (SHOW THE LABEL WHERE POSSIBLE).
US CLASSIFICATION AND LABEL TEXT
INDICATION OF DANGER: HARMFUL.
RISK STATEMENTS: IRRITATING TO RESPIRATORY SYSTEM. RISK OF
SERIOUS DAMAGE TO EYES. MAY CAUSE SENSITIZATION BY SKIN CONTACT.
POSSIBLE RISK OF IMPAIRED FERTILITY.
SAFETY STATEMENTS: IN CASE OF CONTACT WITH EYES, RINSE
IMMEDIATELY WITH PLENTY OF WATER AND SEEK MEDICAL ADVICE. WEAR
SUITABLE PROTECTIVE CLOTHING, GLOVES, AND EYE/FACE PROTECTION.
IN CASE OF ACCIDENT OR IF YOU FEEL UNWELL, SEEK MEDICAL ADVICE
IMMEDIATELY (SHOW THE LABEL WHERE POSSIBLE).
US STATEMENTS: TARGET ORGAN(S): LIVER. BONE MARROW.
UNITED STATES REGULATORY INFORMATION
SARA LISTED: YES
DEMINIMIS: 1 %
NOTES: THIS PRODUCT IS SUBJECT TO SARA SECTION 313 REPORTING
REQUIREMENTS.
TSCA INVENTORY ITEM: YES
CANADA REGULATORY INFORMATION
WHMIS CLASSIFICATION: THIS PRODUCT HAS BEEN CLASSIFIED IN
ACCORDANCE WITH THE HAZARD CRITERIA OF THE CPR, AND THE MSDS
CONTAINS ALL THE INFORMATION REQUIRED BY THE CPR.
DSL: YES
NDSL: NO
SECTION 16 - OTHER INFORMATION
DISCLAIMER
FOR R&D USE ONLY. NOT FOR DRUG, HOUSEHOLD OR OTHER USES.
WARRANTY
THE ABOVE INFORMATION IS BELIEVED TO BE CORRECT BUT DOES NOT
PURPORT TO BE ALL INCLUSIVE AND SHALL BE USED ONLY AS A GUIDE. THE
INFORMATION IN THIS DOCUMENT IS BASED ON THE PRESENT STATE OF OUR
KNOWLEDGE AND IS APPLICABLE TO THE PRODUCT WITH REGARD TO
APPROPRIATE SAFETY PRECAUTIONS. IT DOES NOT REPRESENT ANY
GUARANTEE OF THE PROPERTIES OF THE PRODUCT. BIOBASIC,
SHALL NOT BE HELD LIABLE FOR ANY DAMAGE RESULTING FROM HANDLING OR
FROM CONTACT WITH THE ABOVE PRODUCT. SEE REVERSE SIDE OF INVOICE
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OR PACKING SLIP FOR ADDITIONAL TERMS AND CONDITIONS OF SALE.
COPYRIGHT 2007 BIOBASIC. LICENSE GRANTED TO MAKE UNLIMITED
PAPER COPIES FOR INTERNAL USE ONLY.
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