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Section 1 - Chemical Product and Company Identification |
MSDS Name: Quinoline
Catalog Numbers:
AC132190000, AC132190010, AC132195000, AC221140000, AC221140050,
AC221140250, AC221141000, AC221145000, AC418790000, AC418790050,
AC418790250, AC418791000, Q35-500
Synonyms:
1-Azanaphthalene; 1-Benzazine; Benzopyridine
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
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Section 2 - Composition, Information on Ingredients
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| CAS# |
Chemical Name |
Percent |
EINECS/ELINCS |
| 91-22-5 |
Quinoline |
>96 | 202-051-6 |
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Section 3 - Hazards Identification
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EMERGENCY OVERVIEW
Appearance: clear yellow to brown liquid.
Warning! Causes eye irritation and possible
injury. Harmful in contact with skin and if swallowed. Possible
risks of irreversible effects. Causes skin and respiratory tract
irritation. Cancer suspect agent. May cause liver damage.
Target Organs: Liver, respiratory system, eyes,
skin, optic nerve.
Potential Health Effects
Eye:
May result in corneal injury. May cause retinal damage. Causes
eye irritation and possible burns.
Skin:
Harmful if absorbed through the skin. May cause severe irritation
and possible burns. If absorbed, may cause symptoms similar to those
for ingestion.
Ingestion:
Harmful if swallowed. May cause irritation of the digestive tract.
May cause liver damage.
Absorption of quinoline into the body may lead to nausea, vomiting,
gastro-intestinal cramps, fever, a feeling of dizziness, irregular
rapid pulse, and collapse. Quinoline has been reported to be toxic
to the retina or optic nerve.
Inhalation:
Causes respiratory tract irritation. May cause respiratory muscle
paralysis. Other symptoms include lethargy, irritation, sore
throat, nose bleeds, hoarseness, cough, chest tightness, difficulty
breathing, nausea, vomiting, dizziness, fever. Extreme exposures
could result in a build-up of fluid in the lungs (pulmonary edema)
that might be fatal in severe cases.
Chronic:
Chronic inhalation and ingestion may cause effects similar to those
of acute inhalation and ingestion. Chronic exposure may cause liver
damage. Cancer suspect agent.
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Section 4 - First Aid Measures
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Eyes:
Get medical aid immediately. Immediately flush eyes with plenty of wa
ter for at least 15 minutes.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of
water for at least 15 minutes while removing contaminated clothing
and shoes.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4
cupfuls of milk or water. Never give anything by mouth to an
unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh
air immediately. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen.
Notes to Physician:
Treat symptomatically and supportively.
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Section 5 - Fire Fighting Measures
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General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion.
Extinguishing Media:
In case of fire, use water, dry chemical, chemical foam, or
alcohol-resistant foam.
Flash Point: 100.6 deg C ( 213.08 deg F)
Autoignition Temperature: 480 deg C ( 896.00 deg F)
Explosion Limits, Lower: 1.20
Upper: 7.00
NFPA Rating:
(estimated) Health: 3; Flammability: 2; Instability: 0
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Section 6 - Accidental Release Measures
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General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container. Avoid runoff into storm sewers and
ditches which lead to waterways. Clean up spills immediately,
observing precautions in the Protective Equipment section. Provide
ventilation.
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Section 7 - Handling and Storage
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Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Avoid breathing vapors from heated material. Do
not get in eyes, on skin, or on clothing. Do not ingest or inhale.
Use only in a chemical fume hood. Discard contaminated shoes.
Storage:
Keep away from sources of ignition. Do not store in direct sunlight.
Store in a tightly closed container. Store in a cool, dry,
well-ventilated area away from incompatible substances.
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Section 8 - Exposure Controls, Personal Protection
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Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate general or
local exhaust ventilation to keep airborne concentrations below the
permissible exposure limits.
Exposure Limits
| Chemical Name |
ACGIH |
NIOSH |
OSHA - Final PELs |
| Quinoline
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none listed
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none listed
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none listed
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OSHA Vacated PELs:
Quinoline:
No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes:
Wear chemical splash goggles and face shield.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.
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Section 9 - Physical and Chemical Properties
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Physical State: Liquid
Appearance: clear yellow to brown
Odor: peculiar odor
pH: 7.3
Vapor Pressure: 1 mm Hg @59.7C
Vapor Density: 4.45
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 237 deg C
Freezing/Melting Point:-15 deg C
Decomposition Temperature:Not available.
Solubility: slightly soluble in cold water
Specific Gravity/Density: 1.0850
Molecular Formula:C9H7N
Molecular Weight:129.0557
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Section 10 - Stability and Reactivity
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Chemical Stability:
Stable under normal temperatures and pressures. Substance undergoes
color change upon exposure to light and air.
Conditions to Avoid:
Incompatible materials, light, excess heat.
Incompatibilities with Other Materials:
Perchromates, dinitrogen tetraoxide, hydrogen peroxide, linseed oil +
thionyl chloride, maleic anhydride.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen gas.
Hazardous Polymerization: Has not been reported.
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Section 11 - Toxicological Information
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RTECS#:
CAS# 91-22-5:
VA9275000
LD50/LC50:
CAS# 91-22-5:
Draize test, rabbit,
skin: 100 mg/24H Moderate;
Oral,
rat: LD50 = 331 mg/kg;
Skin,
rabbit: LD50 = 540 uL/kg;
.
Carcinogenicity:
CAS# 91-22-5:
- ACGIH:
Not listed.
- California:
carcinogen, initial date 10/24/97
- NTP:
Not listed.
- IARC:
Not listed.
Epidemiology:
No information found
Teratogenicity:
No information found
Reproductive Effects:
No information found
Mutagenicity:
Mutation data reported.
Neurotoxicity:
No information found
Other Studies:
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Section 12 - Ecological Information
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Ecotoxicity:
No data available.
"Several studies of aquatic toxicity have shown lethal concentrations
in about 10 different types of fish to range from 5 to 50 mg/l. The
toxic threshold in Daphnia is 52 mg/l."
Environmental:
No information available.
Physical:
No information available.
Other:
No information available.
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Section 13 - Disposal Considerations
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Chemical waste generators must determine whether a discarded chemical is classified
as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3.
Additionally, waste generators must consult state and local hazardous waste regulations to
ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
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Section 14 - Transport Information
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US DOT |
Canada TDG |
| Shipping Name: |
QUINOLINE |
QUINOLINE |
| Hazard Class: |
6.1 |
6.1 |
| UN Number: |
UN2656 |
UN2656 |
| Packing Group: |
III |
III |
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Section 15 - Regulatory Information
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US FEDERAL
TSCA
CAS# 91-22-5 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
CAS# 91-22-5: 5000 lb final RQ; 2270 kg final RQ
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 91-22-5: immediate.
Section 313
This material contains Quinoline
(CAS# 91-22-5, >96%),which is subject to the reporting requirements
of Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
CAS# 91-22-5 is listed as a hazardous air pollutant (HAP).
This material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
CAS# 91-22-5 is listed as a Hazardous Substance under the CWA.
None of the chemicals in this
product are listed as Priority Pollutants under the CWA.
None of the chemicals in this
product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product
are considered highly hazardous by OSHA.
STATE
CAS# 91-22-5 can be found on the
following state right to know lists: California, New Jersey,
Pennsylvania, Minnesota, Massachusetts.
California Prop 65
The following statement(s) is(are) made in order to comply with
the California Safe Drinking Water Act:
WARNING: This product contains Quinoline, a chemical known to the
state of California to cause cancer.
California No Significant Risk Level:
None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
XN
Risk Phrases:
R 21/22 Harmful in contact with skin and if swallowed.
R 37/38 Irritating to respiratory system and skin.
R 40 Limited evidence of a carcinogenic effect.
R 41 Risk of serious damage to eyes.
R 68 Possible risk of irreversible effects.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately with plenty of
water and seek medical advice.
S 36/37/39 Wear suitable protective clothing, gloves and eye/face pr
otection.
WGK (Water Danger/Protection)
CAS# 91-22-5: 2
Canada - DSL/NDSL
CAS# 91-22-5 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of B3, D1B, E.
This product has been classified in accordance with the hazard
criteria of the Controlled Products Regulations and the MSDS
contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
CAS# 91-22-5 is listed on the Canadian Ingredient Disclosure List.
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Section 16 - Additional Information
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MSDS Creation Date: 12/12/1997
Revision #6 Date: 10/29/2007
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no event shall Fisher be liable
for any claims, losses, or damages of any third party or for lost profits
or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if Fisher has been advised of
the possibility of such damages.
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