|
Section 1 - Chemical Product and Company Identification |
MSDS Name: 4-Aminobenzyl cyanide, 99%
Catalog Numbers:
AC103210000, AC103210100
Synonyms:
4-Aminophenylacetonitrile; 4-Aminobenzyl cyanide.
Company Identification:
Acros Organics N.V.
One Reagent Lane
Fair Lawn, NJ 07410
For information in North America, call: 800-ACROS-01
For emergencies in the US, call CHEMTREC: 800-424-9300
|
Section 2 - Composition, Information on Ingredients
|
| CAS# |
Chemical Name |
Percent |
EINECS/ELINCS |
| 3544-25-0 |
4-Aminobenzyl cyanide |
99 | 222-587-4 |
|
Section 3 - Hazards Identification
|
EMERGENCY OVERVIEW
Appearance: yellow to brown crystalline powder.
Warning! May be harmful if swallowed, inhaled, or
absorbed through the skin. May cause eye and skin irritation. May
cause respiratory tract irritation.
Target Organs: No data found.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. May be harmful if absorbed through the
skin.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and
diarrhea. May be harmful if swallowed.
Inhalation:
May cause respiratory tract irritation. May be harmful if inhaled.
Chronic:
May be metabolized to cyanide which in turn acts by inhibiting
cytochrome oxidase impairing cellular respiration. Chronic exposure
to cyanide solutions may lead to the development of a "cyanide" rash,
characterized by itching, and by macular, papular, and vesicular
eruptions, and may be accompanied by secondary infections. Exposure
to small amounts of cyanide compounds over long periods of time is
reported to cause loss of appetite, headache, weakness, nausea,
dizziness, and symptoms of irritation of the upper respiratory tract
and eyes.
|
Section 4 - First Aid Measures
|
Eyes:
In case of contact, immediately flush eyes with plenty of water for a
t least 15 minutes. Get medical aid.
Skin:
In case of contact, immediately flush skin with plenty of water for
at least 15 minutes while removing contaminated clothing and shoes.
Get medical aid immediately. Wash clothing before reuse.
Ingestion:
If swallowed, do not induce vomiting unless directed to do so by
medical personnel. Never give anything by mouth to an unconscious
person. Get medical aid.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial
respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.
|
Section 5 - Fire Fighting Measures
|
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. Combustion generates toxic fumes. This material in
sufficient quantity and reduced particle size is capable of creating
a dust explosion.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.
Flash Point: > 110 deg C (> 230.00 deg F)
Autoignition Temperature: Not available.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating:
(estimated) Health: 2; Flammability: 1; Instability: 0
|
Section 6 - Accidental Release Measures
|
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal
container. Clean up spills immediately, observing precautions in the
Protective Equipment section. Provide ventilation.
|
Section 7 - Handling and Storage
|
Handling:
Wash thoroughly after handling. Wash thoroughly after handling.
Remove contaminated clothing and wash before reuse. Minimize dust
generation and accumulation. Avoid contact with eyes, skin, and
clothing. Use only with adequate ventilation. Avoid breathing dust.
Storage:
Store in a tightly closed container. Store in a cool, dry,
well-ventilated area away from incompatible substances.
|
Section 8 - Exposure Controls, Personal Protection
|
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate
ventilation to keep airborne concentrations low.
Exposure Limits
| Chemical Name |
ACGIH |
NIOSH |
OSHA - Final PELs |
| 4-Aminobenzyl cyanide
|
none listed
|
none listed
|
5 mg/m3 TWA (listed under Cyanide anion).
|
OSHA Vacated PELs:
4-Aminobenzyl cyanide:
No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.
|
Section 9 - Physical and Chemical Properties
|
Physical State: Crystalline powder
Appearance: yellow to brown
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Vapor Density: 4.6
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 312 deg C @ 760 mm Hg
Freezing/Melting Point:44-48 deg C
Decomposition Temperature:Not available.
Solubility: slightly soluble
Specific Gravity/Density:Not available.
Molecular Formula:C8H8N2
Molecular Weight:132.16
|
Section 10 - Stability and Reactivity
|
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Dust generation.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong reducing agents, strong acids, and
strong bases.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide, cyanides.
Hazardous Polymerization: Has not been reported.
|
Section 11 - Toxicological Information
|
RTECS#:
CAS# 3544-25-0
unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
CAS# 3544-25-0:
Not listed by ACGIH, IARC, NTP, or CA Prop 65.
Epidemiology:
No information found
Teratogenicity:
No information found
Reproductive Effects:
No information found
Mutagenicity:
No information found
Neurotoxicity:
No information found
Other Studies:
|
Section 12 - Ecological Information
|
Ecotoxicity:
Bacteria: Phytobacterium phosphoreum: EC50 = 0.36-0.40 mg/L; 5,15,30
minutes; Microtox test; 15 degrees C
|
Section 13 - Disposal Considerations
|
Chemical waste generators must determine whether a discarded chemical is classified
as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3.
Additionally, waste generators must consult state and local hazardous waste regulations to
ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
|
Section 14 - Transport Information
|
| |
US DOT |
Canada TDG |
| Shipping Name: |
DOT regulated - small quantity provisions apply (see 49CFR173.4) |
NITRILES SOLID TOXIC NOS (4-AMINOBENZYL CYANIDE) |
| Hazard Class: |
|
6.1 |
| UN Number: |
|
UN3276 |
| Packing Group: |
|
III |
|
Section 15 - Regulatory Information
|
US FEDERAL
TSCA
CAS# 3544-25-0 is not listed on the TSCA inventory.
It is for research and development use only.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants.
This material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product
are listed as Hazardous Substances under the CWA.
CAS# 3544-25-0 is listed as a Priority Pollutant under the Clean
Water Act.
CAS# 3544-25-0 is listed as a Toxic Pollutant under the Clean Water
Act.
OSHA:
None of the chemicals in this product
are considered highly hazardous by OSHA.
STATE
CAS# 3544-25-0 can be found on the
following state right to know lists: California, (listed as Cyanides,
inorganic salts), New Jersey, (listed as Cyanide anion), New Jersey,
(listed as Cyanides, inorganic salts), Pennsylvania, (listed as
Cyanide anion), Massachusetts, (listed as Cyanide anion).
California Prop 65
California No Significant Risk Level:
None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
XN
Risk Phrases:
R 20/21/22 Harmful by inhalation, in contact with skin and if
swallowed.
Safety Phrases:
S 36/37 Wear suitable protective clothing and gloves.
WGK (Water Danger/Protection)
CAS# 3544-25-0: No information available.
Canada - DSL/NDSL
None of the chemicals in this product are listed on the DSL or NDSL list.
Canada - WHMIS
not available.
This product has been classified in accordance with the hazard
criteria of the Controlled Products Regulations and the MSDS
contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
CAS# 3544-25-0 (listed as Cyanides, inorganic salts) is listed on the Canadian Ingredient Disclosure List.
|
Section 16 - Additional Information
|
MSDS Creation Date: 7/07/1999
Revision #4 Date: 9/26/2007
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no event shall Fisher be liable
for any claims, losses, or damages of any third party or for lost profits
or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if Fisher has been advised of
the possibility of such damages.
|
|