EMS CATALOG NO: 12300
EMS PRODUCT: Sodium Cacodylate
DATE: 10/30/2007
PAGE NUMBER: One of 7
MATERIAL SAFETY DATA SHEET
The information contained herein is based on data considered accurate. However, no
warranty is expressed or implied regarding the accuracy of these data or the results to
be obtained from the use thereof.
Electron Microscopy Sciences assumes no responsibility for personal injury or property
damage to vendees, users or third parties caused by the material. Such vendees or
users assume all risks associated with the use of the material.
ELECTRON MICROSCOPY SCIENCES
1560 INDUSTRY ROAD
P.O. BOX 550
HATFIELD, PA 19440 24 HOUR EMERGENCY PHONE NUMBER
(215) 412-8400 CHEMTREC: (800) 424-9300
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FOR PRODUCT AND SALES INFORMATION
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CONTACT ELECTRON MICROSCOPY SCIENCES OFFICE ABOVE.
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PRODUCT IDENTIFICATION
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COMMON NAME: Sodium Cacodylate Trihydrate
COMMERCIAL NAME(S): Cacodylic Acid, Sodium Salt
SYNONYM: Sodium Dimethylarsinate Trihydrate, Cacodylate Acid
CHEMICAL NAME: Not available.
CHEMICAL FAMILY: Not available.
CHEMICAL FORMULA: (CH3)2AsO2Na.3H2O
CAS#: 124-65-2
RTECS: CH7700000
TSCA: 8(b) INVENTORY: Cacodylic acid, sodium salt
CI#: Not available.
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COMPOSITION AND INFORMATION ON INGREDIENTS
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NAME: Sodium Dimethylarsinate Trihydrate
CAS#: 124-65-2
% BY WEIGHT: 100
TOXICOLOGICAL DATA ON INGREDIENTS:
ORAL (LD50): Acute: 2600 mg/kg [Rat]. 4mg/kg [Mouse].
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HAZARDS IDENTIFICATION
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POTENTIAL ACUTE HEALTH EFFECTS:
Extremely hazardous in case of ingestion, of inhalation. Hazardous in case of skin
contact (irritant, permeator), of eye contact (irritant). Severe over-exposure can result
in death.
POTENTIAL CHRONIC HEALTH EFFECTS:
Extremely hazardous in case of ingestion, of inhalation. Hazardous in case of skin
contact (irritant, permeator), of eye contact (irritant).
CARCINOGENIC EFFECTS: Classified A! (confirmed for human.)
by ACGIH, 1 (Known.) by NTP, +(PROVEN) by OSHA.
MUTAGENIC EFFECTS: Not available.
TERATOGENIC EFFECTS: Not available.
DEVELOPMENTAL TOXICITY: Not available.
The substance is toxic to blood, kidneys, lungs, liver.
Repeated or prolonged exposure to the substance can produce target organs damage.
Repeated exposure to an highly toxic material may produce general deterioration of
health by an accumulation in one or many human organs.
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FIRST AID MEASURES
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EYE CONTACT:
Check for and remove any contact lenses. Immediately flush eyes with running water
for at least 15 minutes, keeping eyelids open. Cold water may be used. Do not use an
eye ointment. Seek medical attention.
SKIN CONTACT:
After contact with skin, was immediately with plenty of water. Gently and thoroughly
wash the contaminated skin with running water and non-abrasive soap. Be particularly
careful to clean folds, crevices, creases and groin. Cold water may be used. Cover the
irritated skin with an emollient. If irritation persists, seek medical attention. Wash
contaminated clothing before reusing.
SERIOUS SKIN CONTACT:
Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial
cream. Seek immediate medical attention.
Sodium Cacodylate 2
Catalog #12300
INHALATION:
Allow the victim to rest in a well ventilated area. Seek immediate medical attention.
SERIOUS INHALATION:
Evacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a
collar, tie, belt or waistband. If breathing is difficult, administer oxygen. If the victim is
not breathing, perform mouth-to-mouth resuscitation. Seek medical attention.
INGESTION:
Induce vomiting. Call a physician immediately.
Loosen tight clothing such as a collar, tie, belt or waistband. If the victim is not
breathing, perform mouth-to-mouth resuscitation. Seek immediate medical attention.
SERIOUS INGESTION: Not available.
Note to Physician:
If emesis is unsuccessful after two doses of Ipecac, consider gastric lavage.
Monitor urine arsenic level. Alkalization of urine may help prevent disposition
Of red cell breakdown products in renal tubular cells . If acute exposure is
Significant, maintain high urine output and monitor volume status, preferably
With central venous pressure line. Abdominal X-rays should be done routinely
For all ingestions. Chelation therapy with BAL, followed by n-penicillamine is
Recommended, but specific dosing guidelines are not clearly established.
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FIRE AND EXPLOSION DATA
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FLAMMABILITY OF THE PRODUCT: May be combustible at high temperature.
AUTO-IGNITION TEMPERATURE: Not available.
FLASH POINTS: Not available.
FLAMMABLE LIMITS: Not available.
PRODUCTS OF COMBUSTION: These products are carbon oxides (CO, CO2). Some
metallic oxides.
FIRE HAZARDS IN PRESENCE OF VARIOUS SUBSTANCES: Not available.
EXPLOSION HAZARDS IN PRESENCE OF VARIOUS SUBSTANCES:
RISKS OF EXPLOSION OF THE PRODUCT IN PRESENCE OF MECHANICAL
IMPACT: Not available.
RISKS OF EXPLOSION OF THE PRODUCT IN PRESENCE OF STATIC
DISCHARGE: Not available.
FIRE FIGHTING MEDIA AND INSTRUCTIONS:
SMALL FIRE: Use DRY chemical powder.
LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
SPECIAL REMARKS ON FIRE HAZARDS: Not available.
SPECIAL REMARKS ON EXPLOSION HAZARDS: Not available.
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ACCIDENTAL RELEASE MEASURES
Sodium Cacodylate 3
Catalog #12300
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SMALL SPILL: Use appropriate tools to put the spilled solid in a convenient waste
disposal container.
LARGE SPILL: Use a shovel to put the material into a convenient waste disposal
container.
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HANDLING AND STORAGE
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PRECAUTIONS: Keep locked up. Keep away from heat. Keep away from sources of
ignition. Empty containers pose a fire risk, evaporate the residue under a fume hood.
Ground all equipment containing material. Do not ingest. Do not breathe dust. Wear
suitable protective clothing. In case of insufficient ventilation, wear suitable respiratory
equipment. If ingested, seek medical advice immediately and show the container or the
label. Avoid contact with skin and eyes.
STORAGE: Keep container dry. Keep in a cool place. Ground all equipment containing
material. Keep container tightly closed. Keep in a cool, well-ventilated place. Highly
toxic or infectious materials should be stored in a separate locked safety cabinet or
room.
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EXPOSURE CONTROLS/PERSONAL PROTECTION
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ENGINEERING CONTROLS: Use process enclosures, local exhaust ventilation, or other
engineering controls to keep airborne levels below recommended exposure limits. If
user operations generate dust, fume or mist, use ventilation to keep exposure to
airborne contaminants below the exposure limit.
PERSONAL PROTECTION: Splash goggles. Lab coat. Dust respirator. Be sure to use an
approved/certified respirator or equivalent.
PERSONAL PROTECTION IN CASE OF A LARGE SPILL: Splash goggles. Full suit. Dust
respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoid
inhalation of the product. Suggested protective clothing might not be sufficient; consult
a specialist BEFORE handling this product.
EXPOSURE LIMITS: Not available.
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PHYSICAL AND CHEMICAL PROPERTIES
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PHYSICAL STATE AND APPEARANCE: Solid. (Crystalline solid.)
Sodium Cacodylate 4
Catalog #12300
ODOR: Odorless
TASTE: Not available.
COLOR: White.
MOLECULAR WEIGHT: 214.03 g/mole
pH (1% SOLN/WATER): Soluble in water
BOILING POINT: Decomposes.
MELTING POINT: 60oC (140oF)
CRITICAL TEMPERATURE: Not available.
SPECIFIC GRAVITY: 0.58
VAPOR PRESSURE: Not applicable.
VAPOR DENSITY: 7.4 (Air=1)
VOLATILITY: Not available.
ODOR THRESHOLD: Not available.
WATER/OIL DIST. COEFF.: Not available.
IONICITY (IN WATER): Not available.
DISPERSION PROPERTIES: See solubility in water, methanol.
SOLUBILITY: Soluble in cold water, methanol.
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STABILITY AND REACTIVITY DATA
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STABILITY: The product is stable under ordinary conditions of use and storage.
INSTABILITY TEMPERATURE: Not available.
CONDITIONS OF INSTABILITY: Not available.
INCOMPATIBILITY WITH VARIOUS SUBSTANCES: Reducing agents, aluminum, zinc,
Common metals (corrosive) and sodium borohydride.
CORROSIVITY: Non-corrosive in presence of glass.
SPECIAL REMARKS ON REACTIVITY: Not available.
SPECIAL REMARKS ON CORROSIVITY: Not available.
POLYMERIZATION: No.
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TOXICOLOGICAL INFORMATION
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ROUTES OF ENTRY: Dermal contact. Eye contact. Inhalation. Ingestion.
TOXICITY TO ANIMALS: Acute oral toxicity (LD50): 4mg/kg [Mouse].
CHRONIC EFFECTS ON HUMANS:
CARCINOGENIC EFFECTS: Classified A1 (Confirmed for human.)
by ACGIH, 1 (Known.) by NTP, + (PROVEN) by OSHA.
The substance is toxic to blood, kidneys, lungs, liver.
OTHER TOXIC EFFECTS ON HUMANS: Extremely hazardous in case of
ingestion, of inhalation. Hazardous in case of skin contact
(irritant, permeator).
SPECIAL REMARKS ON TOXICITY TO ANIMALS: Not available.
SPECIAL REMARKS ON CHRONIC EFFECTS ON HUMANS: Not available.
SPECIAL REMARKS ON OTHER TOXIC EFFECTS ON HUMANS: Not available.
Sodium Cacodylate 5
Catalog #12300
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ECOLOGICAL INFORMATION
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ECOTOXICITY: This material is expected to be slightly toxic to aquatic life.
BOD5 AND COD: Not available.
PRODUCTS OF BIODEGRADATION: Possibly hazardous short term degradation products
are not likely. However, long term degradation products may arise.
TOXICITY OF THE PRODUCTS OF BIODEGRADATION: The products of degradation are
more toxic.
SPECIAL REMARKS ON THE PRODUCTS OF BIODEGRADATION: Not available.
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DISPOSAL CONSIDERATIONS
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WASTE DISPOSAL: Recycle to process, if possible. Consult your local or regional
authorities.
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TRANSPORT INFORMATION
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DOT CLASSIFICATION: CLASS 6.1 : Poisonous material.
IDENTIFICATION: Sodium Cacodylate UN 1688 PG:II
SPECIAL PROVISIONS FOR TRANSPORT: Marine Pollutant
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OTHER REGULATORY INFORMATION
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FEDERAL AND STATE REGULATIONS:
CALIFORNIA PROPOSITION 65: This product contains the
following ingredients for which the State of California has
found to cause cancer, birth defects or other reproductive
harm, which would require a warning under the statute:
Cacodylic acid, sodium salt
CALIFORNIA PROPORTIONATES 65: This product contains the
following ingredients for which the State of California has
found to cause cancer which would require a warning under
the statute: Cacodylic acid, sodium salt.
PENNSYLVANIA RTK: Cacodylic Acid, sodium salt
MASSACHUSETTS RTK: Cacodylic acid, sodium salt
TSCA 8(b) INVENTORY: Cacodylic acid, sodium salt
SARA 301/304/311/312: Extremely hazardous substances:
Sodium Cacodylate 6
Catalog #12300
Cacodylic acid, sodium salt
SARA 313 Toxic chemical notification and release reporting:
Cacodylic Acid, sodium salt
CERCLA: Hazardous substances: Cacodylic acid, sodium salt
OTHER REGULATIONS:
OSHA: Hazardous by definition of Hazard Communication
Standard (29 CFR 1910.1200)
OTHER CLASSIFICATIONS:
WHMIS (CANADA): CLASS D-1A: Material causing immediate and
serious toxic effects (VERY TOXIC).
CLASS D-2A: Material causing other toxic
effects (VERY TOXIC).
DSCLA (EEC): R36/38-Irritating to eyes and skin.
R45-May cause cancer.
HMIS (U.S.A.):
HEALTH HAZARD: 3
FIRE HAZARD: 0
REACTIVITY: 0
PERSONAL PROTECTION: E
NATIONAL FIRE PROTECTION ASSOCIATION (U.S.A.)
HEALTH: 3
FLAMMABILITY: 0
REACTIVITY: 0
SPECIFIC HAZARD:
PROTECTIVE EQUIPMENT:
Gloves.
Lab coat.
Dust respirator. Be sure to use an approved/certified respirator or equivalent. Wear
appropriate respirator when ventilation is inadequate.
Splash goggles.
Sodium Cacodylate 7
Catalog #12300
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