Page 1/5
Safety Data Sheet
according to 1907/2006/EC, Article 31
Printing date 31.10.2007 Revision: 31.10.2007
Hazardous according to criteria of Worksafe Australia
1 Identification of substance
Trade name: HaloTag庐 diAcFAM Ligand
Article number: G8272
Application of the substance / the preparation: Laboratory chemicals
Manufacturer/Supplier:
Promega Corporation
2800 Woods Hollow Road
Madison, WI 53711
U.S.A.
1-608-274-4330
1-800-356-9526
MSDS author: Regulatory.Affairs@promega.com
Further information obtainable from:
37 Nelson Street
Annandale NSW 2038
AUSTRALIA
Sydney
Tel: (61) 02 9565 1100
Fax: (61) 02 9550 4454
Toll free Tel: 1800 225 123
Toll free Fax: 1800 626 017
Melbourne
Tel: (61) 03 9818 1466
Fax: (61) 03 9818 1244
Toll free Tel: 1800 335 435
E-mail Address: aus_custserv@au.promega.com
Web Address: www.promega.com/au/
Information in case of emergency:
CHEMTREC 1-800-424-9300
For call originating outside the United States dial 001-703-527-3887
2 Hazards identification
Hazard description:
Xn Harmful
Information concerning to particular hazards to man and environment
The product has to be labelled due to the calculation procedure of the "General Classification guideline for
preparations of the EU" in the latest valid version.
Harmful if swallowed.
(Contd. on page 2)
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Page 2/5
Safety Data Sheet
according to 1907/2006/EC, Article 31
Printing date 31.10.2007 Revision: 31.10.2007
Trade name: HaloTag庐 diAcFAM Ligand
(Contd. of page 1)
Irritating to eyes and skin.
Classification system:
The classification is in line with current EC lists. It is extended, by information from technical literature and
company information.
3 Composition/information on ingredients
Chemical characterization
Description: Mixture of substances listed below with nonhazardous additions.
Components:
CAS: 67-68-5 dimethyl sulfoxide 75-100%
RTECS: PV 6210000
Additional information: For the wording of the listed risk phrases refer to section 16.
4 First aid measures
General information:
Symptoms of poisoning may even occur after several hours; therefore medical observation for at least 48 hours
after the accident.
After inhalation: In case of unconsciousness place patient stably in side position for transportation.
After skin contact: Immediately wash with soap, water and rinse thoroughly.
After eye contact:
Rinse opened eye for several minutes under running water. If symptoms persist, consult a doctor.
After swallowing: Call for a doctor immediately.
5 Fire fighting measures
Suitable extinguishing agents:
CO2, powder or water spray. Fight larger fires with water spray or alcohol resistant foam.
6 Accidental release measures
Person-related safety precautions: Not required.
Measures for environmental protection: Do not allow to enter sewers/ surface or ground water.
Measures for cleaning/collecting: Dispose contaminated material as waste according to item 13.
7 Handling and storage
Handling
Information for safe handling:
Keep receptacles tightly sealed.
No special precautions are necessary if used correctly.
Information about fire - and explosion protection: No special measures required.
Storage
Requirements to be met by storerooms and receptacles: No special requirements.
Information about storage in one common storage facility: Not required.
Further information about storage conditions: Keep receptacle tightly sealed.
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(Contd. on page 3)
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Safety Data Sheet
according to 1907/2006/EC, Article 31
Printing date 31.10.2007 Revision: 31.10.2007
Trade name: HaloTag庐 diAcFAM Ligand
(Contd. of page 2)
8 Exposure controls and personal protection gear
Additional information about design of technical facilities: No further data; see item 7.
Ingredients with limit values that require monitoring at the workplace:
67-68-5 dimethyl sulfoxide
WEEL (USA) 250 ppm
Additional information: The lists valid during the making were used as basis.
Personal protective equipment
General protective and hygienic measures
Keep away from foodstuffs, beverages and feed.
Immediately remove all soiled and contaminated clothing
Wash hands before breaks and at the end of work.
Avoid contact with the eyes and skin.
Respiratory protection: Not required.
Protection of hands:
Protective gloves.
Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation
Material of gloves:
The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and
varies from manufacturer to manufacturer. As the product is a preparation of several substances, the resistance
of the glove material can not be calculated in advance and has therefore to be checked prior to the application.
Penetration time of glove material:
The exact break trough time has to be found out by the manufacturer of the protective gloves and has to be
observed.
Eye protection: Tightly sealed goggles.
9 Physical and chemical properties
General Information
Solid.
Form:
Colourless
Colour:
Characteristic
Odour:
Change in condition
Melting point/Melting range: 18.45掳C (65掳F)
Boiling point/Boiling range: 189掳C (372掳F)
> 55掳C (> 131掳F)
Flash point:
270掳C (518掳F)
Ignition temperature:
Product is not selfigniting.
Self-igniting:
Product does not present an explosion hazard.
Danger of explosion:
Explosion limits:
1.8 Vol %
Lower:
Zers Vol %
Upper:
Vapour pressure at 20掳C (68掳F): 2.5 hPa (2 mm Hg)
1.1 g/cm鲁
Density at 20掳C (68掳F):
Solubility in / Miscibility with
Soluble
Water:
(Contd. on page 4)
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Safety Data Sheet
according to 1907/2006/EC, Article 31
Printing date 31.10.2007 Revision: 31.10.2007
Trade name: HaloTag庐 diAcFAM Ligand
(Contd. of page 3)
Solvent content:
99.0 %
Organic solvents:
10 Stability and reactivity
Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications.
Dangerous reactions: No dangerous reactions known
Dangerous decomposition products: No dangerous decomposition products known
11 Toxicological information
Acute toxicity:
LD/LC50 values relevant for classification:
67-68-5 dimethyl sulfoxide
Oral LD50 14500 mg/kg (Rat)
Irritation of eyes acute 500 mg (Rabbit)
mild irritation
Primary irritant effect:
on the skin: Irritant to skin and mucous membranes.
on the eye: Irritating effect.
Sensitization: No sensitizing effects known.
Additional toxicological information:
The product shows the following dangers according to the calculation method of the General EU Classification
Guidelines for Preparations as issued in the latest version.
Harmful
Irritant
12 Ecological information
General notes:
Water hazard class 1 (German Regulation) (Self-assessment): slightly hazardous for water.
Do not allow undiluted product or large quantities of it to reach ground water, water course or sewage system.
13 Disposal considerations
Product:
Recommendation
Must not be disposed together with household garbage. Do not allow product to reach sewage system.
Uncleaned packaging:
Recommendation: Disposal must be made according to official regulations.
Recommended cleansing agents: Water, if necessary together with cleansing agents.
14 Transport information
Land transport ADR/RID (cross-border)
ADR/RID class: -
(Contd. on page 5)
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Safety Data Sheet
according to 1907/2006/EC, Article 31
Printing date 31.10.2007 Revision: 31.10.2007
Trade name: HaloTag庐 diAcFAM Ligand
(Contd. of page 4)
Maritime transport IMDG:
-
IMDG Class:
Marine pollutant: No
Air transport ICAO-TI and IATA-DGR:
ICAO/IATA Class: -
* 15 Regulations
Australian Inventory of Chemical Substances
67-68-5 dimethyl sulfoxide
Labelling according to EU guidelines:
The product has been classified and marked in accordance with EU Directives / Ordinance on Hazardous
Materials
Hazard-determining components of labelling:
dimethyl sulfoxide
Risk phrases:
Harmful if swallowed.
Irritating to eyes and skin.
Safety phrases:
Avoid contact with eyes.
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing and gloves.
This material and its container must be disposed of as hazardous waste.
National regulations
Technical instructions (air):
Class Share in %
NK 99.0
Waterhazard class: Water hazard class 1 (Self-assessment): slightly hazardous for water.
16 Other information
This information is based on our present knowledge. However, this shall not constitute a guarantee for any
specific product features and shall not establish a legally valid contractual relationship.
Department issuing MSDS:
Promega Corporation
Safety Department
2800 Woods Hollow Road
Madison, WI 53711
U.S.A.
* Data compared to the previous version altered.
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