SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 26/OCT/2004
Date Updated: 14/MAY/2004
Version 1.6
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name ADIPIC ACID FREE ACID
Product Number A5252
Company Sigma-Aldrich Pty, Ltd
Unit 2, 14 Anella Avenue
Castle Hill NSW 1765
Technical Phone # +61 2 9841 0555
Fax +61 2 9841 0500
Emergency Phone # +61 2 9841 0566
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
ADIPIC ACID 124-04-9 204-673-3 607-144-00-9
Formula C6H10O4
Molecular Weight 146.14 AMU
Synonyms Acifloctin * Acinetten * Adilactetten * Adipic
acid (ACGIH) * Adipinic acid *
1,4-Butanedicarboxylic acid * Hexanedioic acid *
1,6-Hexanedioic acid * Kyselina adipova (Czech)
* Molten adipic acid
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Irritating to eyes.
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER SKIN CONTACT
In case of contact, immediately wash skin with soap and copious
amounts of water.
AFTER EYE CONTACT
In case of contact, immediately flush eyes with copious amounts
of water for at least 15 minutes.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
GENERAL INFORMATION
Contamination of the eyes should be treated by immediate and
prolonged irrigation with copious amounts of water.
5 - Fire Fighting Measures
EXPLOSION DATA
Dust Potential: This material, like most materials in powder
form, is capable of creating a dust explosion.
EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.
SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear respirator, chemical safety goggles, rubber boots, and
heavy rubber gloves.
ENVIRONMENTAL PRECAUTION(S)
Avoid contaminating water supply. Avoid contaminating sewers and
waterways with this material.
METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Avoid
raising dust. Ventilate area and wash spill site after material
pickup is complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe dust. Avoid contact
with eyes, skin, and clothing. Avoid prolonged or repeated
exposure.
STORAGE
Conditions of Storage: Keep tightly closed. Keep away from heat,
sparks, and open flame. Store in a cool dry place.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Safety shower and eye bath. Mechanical exhaust required. Ventilate
area - especially low places where heavy vapors might collect.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling. Wash contaminated clothing before
reuse.
EXPOSURE LIMITS
Country Source Type Value
Poland NDS 5 mg/m3
Poland NDSCh 10 mg/m3
Poland NDSP
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Remarks: {OELS ARE VALID FOR DUSTS} PY艁Y
EXPOSURE LIMITS - DENMARK
Source Type Value
OEL TWA 5 mg/m3
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
9 - Physical and Chemical Properties
Appearance Physical State: Solid
Color: White
Form: Fine crystals
Property Value At Temperature or Pressure
pH 2-3 25 藲C Concentration:
24.9 g/l
BP/BP Range 265 藲C 100 mmHg
MP/MP Range 151 藲C
Flash Point 196 藲C Method: closed cup
Flammability N/A
Autoignition Temp 420 藲C
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure 1 mmHg 159.5 藲C
SG/Density N/A
Partition Coefficient Log Kow: 0.093 25 藲C
Viscosity N/A
Vapor Density 5 g/l
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility Solvent: 0.1 g/ml MeOH clear, colorless
10 - Stability and Reactivity
STABILITY
Stable: Stable.
Materials to Avoid: Strong oxidizing agents.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
RTECS NUMBER: AU8400000
ACUTE TOXICITY
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LD50
Oral
Rat
5,050 mg/kg
LD50
Skin
Rabbit
7,940 mg/kg
LD50
Oral
Rat
> 11000 mg/kg
LD50
Intraperitoneal
Rat
275 MG/KG
Remarks: Behavioral:Somnolence (general depressed activity).
Gastrointestinal:Other changes. Blood: Hemorrhage.
LD50
Oral
Mouse
1900 mg/kg
Remarks: Gastrointestinal:Other changes.
LD50
Intravenous
Mouse
680 MG/KG
Remarks: Behavioral:Convulsions or effect on seizure threshold.
Blood: Hemorrhage.
LD50
Oral
Rabbit
> 11000 mg/kg
IRRITATION DATA
Eyes
Rabbit
20 mg
24H
Remarks: Moderate irritation effect
SIGNS AND SYMPTOMS OF EXPOSURE
To the best of our knowledge, the chemical, physical, and
toxicological properties have not been thoroughly investigated.
ROUTE OF EXPOSURE
Skin Contact: May cause skin irritation.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: Causes eye irritation.
Inhalation: Material may be irritating to mucous membranes and
upper respiratory tract. May be harmful if inhaled.
Ingestion: May be harmful if swallowed.
12 - Ecological Information
ECOTOXICOLOGICAL EFFECTS
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Test Type: LC50 Fish
Species: Onchorhynchus mykiss (Rainbow trout)
Time: 48 h
Value: 100 mg/l
Test Type: LC50 Fish
Species: Pimephales promelas (Fathead minnow)
Time: 96 h
Value: 97 mg/l
Test Type: EC50 Daphnia
Species: Daphnia magna
Time: 48 h
Value: 85.7 mg/l
Test Type: EC50 Algae
Species: Scenedesmus subspicatus
Time: 72 h
Value: 31.3 mg/l
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
environmental regulations.
14 - Transport Information
RID/ADR
Non-hazardous for road transport.
IMDG
Non-hazardous for sea transport.
IATA
Non-hazardous for air transport.
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
ANNEX I INDEX NUMBER: 607-144-00-9
INDICATION OF DANGER: Xi
Irritant.
R-PHRASES: 36
Irritating to eyes.
COUNTRY SPECIFIC INFORMATION
Germany
WGK: 1
SWITZERLAND
SWISS POISON CLASS: 4
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
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purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2004 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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