SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 03/NOV/2004
Date Updated: 12/MAR/2004
Version 1.5
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name ALLYL CHLORIDE, 98%
Product Number A30702
Company Sigma-Aldrich Pty, Ltd
Unit 2, 14 Anella Avenue
Castle Hill NSW 1765
Australia
Technical Phone # +61 2 9841 0555
Fax +61 2 9841 0500
Emergency Phone # +61 2 9841 0566
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
ALLYL CHLORIDE 107-05-1 203-457-6 602-029-00-X
Formula C3H5Cl
Molecular Weight 76.53 AMU
Synonyms Allile (cloruro di) (Italian) *
p-Aminopropiofenon (Czech) * Allylchlorid
(German) * Allyl chloride (ACGIH:OSHA) * Allyle
(chlorure d') (French) * Chlorallylene *
Chloroallylene * 3-Chloroprene * 1-Chloro
propene-2 * 3-Chloropropene-1 * 3-Chloropropene
* 1-Chloro-2-propene * alpha-Chloropropylene *
3-Chloropropylene * 3-Chloro-1-propylene *
3-Chlorpropen (German) * NCI-C04615 * 1-Propene,
3-chloro- * 2-Propenyl chloride
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Highly flammable. Very toxic by inhalation. Very toxic to aquatic
organisms.
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER SKIN CONTACT
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.
AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.
SPECIAL RISKS
Specific Hazard(s): Flammable liquid. Emits toxic fumes under
fire conditions.
Explosion Hazards: Vapor may travel considerable distance to
source of ignition and flash back. Container explosion may occur
under fire conditions. Forms explosive mixtures in air.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Absorb on sand or vermiculite and place in closed containers for
disposal. Ventilate area and wash spill site after material
pickup is complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe vapor. Avoid
contact with eyes, skin, and clothing. Avoid prolonged or
repeated exposure.
STORAGE
Conditions of Storage: Keep tightly closed.
Store at 2-8掳C
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Use only in a chemical fume hood. Safety shower and eye bath.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling.
EXPOSURE LIMITS - DENMARK
Source Type Value
OEL TWA 3 mg/m3
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1 ppm
EXPOSURE LIMITS - GERMANY
Source Type Value
TRGS 900 OEL 3 mg/m3
1 ppm
Remarks: =1=
EXPOSURE LIMITS - NORWAY
Source Type Value
OEL 3 mg/m3
1 ppm
Remarks: H
EXPOSURE LIMITS - SWEDEN
Source Type Value
LLV (Level3 mg/m3
1 ppm
Remarks: H
EXPOSURE LIMITS - SWITZERLAND
Source Type Value
OEL OEL 3 mg/m3
1 ppm
Remarks: H*
EXPOSURE LIMITS - UNITED KINGDOM
Source Type Value
OEL LTEL 3 mg/m3
1 ppm
OEL STEL 6 mg/m3
2 ppm
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
9 - Physical and Chemical Properties
Appearance Physical State: Clear liquid
Color: Colorless
Property Value At Temperature or Pressure
pH N/A
BP/BP Range 44 - 46 掳C 760 mmHg
MP/MP Range -130 掳C
Flash Point -32 掳C Method: closed cup
Flammability N/A
Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits Lower: 3.2 %
Upper: 11.2 %
Vapor Pressure 295.207 mmHg 20 掳C
SG/Density 0.935 g/cm3
Partition Coefficient N/A
Viscosity N/A
Vapor Density 2.6 g/l
Saturated Vapor Conc. N/A
Evaporation Rate N/A
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Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility N/A
10 - Stability and Reactivity
STABILITY
Stable: Stable.
Materials to Avoid: Strong oxidizing agents.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide,
Hydrogen chloride gas.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
RTECS NUMBER: UC7350000
ACUTE TOXICITY
LCLO
Inhalation
Human
3,000 ppm
LD50
Oral
Rat
460 mg/kg
Remarks: Behavioral:Tremor. Behavioral:Convulsions or effect on
seizure threshold. Lungs, Thorax, or Respiration:Dyspnea.
LC50
Inhalation
Rat
11,000 mg/m3
2H
Remarks: Sense Organs and Special Senses (Nose, Eye, Ear, and
Taste):Eye:Lacrimation. Gastrointestinal:Ulceration or bleeding
from duodenum. Lungs, Thorax, or Respiration:Respiratory
depression.
LD50
Oral
Mouse
425 mg/kg
Remarks: Behavioral:Somnolence (general depressed activity).
Behavioral:Tremor. Lungs, Thorax, or Respiration:Dyspnea.
LC50
Inhalation
Mouse
11,500 mg/m3
2H
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Remarks: Sense Organs and Special Senses (Nose, Eye, Ear, and
Taste):Eye:Lacrimation. Behavioral:Somnolence (general depressed
activity). Lungs, Thorax, or Respiration:Respiratory depression.
LD50
Intraperitoneal
Mouse
155 MG/KG
LD50
Skin
Rabbit
2066 mg/kg
LC50
Inhalation
Guinea pig
5,800 mg/m3
2H
Remarks: Sense Organs and Special Senses (Nose, Eye, Ear, and
Taste):Eye:Lacrimation. Behavioral:Somnolence (general depressed
activity). Lungs, Thorax, or Respiration:Respiratory depression.
IRRITATION DATA
Eyes
Rat
290 ppm
6H
Skin
Rabbit
10 mg
24H
Remarks: Open irritation test
Eyes
Rabbit
500 mg
Remarks: Moderate irritation effect
Eyes
Guinea pig
290 ppm
6H
SIGNS AND SYMPTOMS OF EXPOSURE
Material is extremely destructive to tissue of the mucous
membranes and upper respiratory tract, eyes, and skin.
Inhalation may result in spasm, inflammation and edema of the
larynxand bronchi, chemical pneumonitis, and pulmonary edema.
Symptoms of exposure may include burning sensation, coughing,
wheezing, laryngitis, shortness of breath, headache, nausea, and
vomiting.
ROUTE OF EXPOSURE
Skin Contact: Causes burns.
Skin Absorption: Harmful if absorbed through skin. Readily
absorbed through skin.
Eye Contact: Causes burns. Lachrymator.
Inhalation: Harmful if inhaled. Material is extremely
destructive to the tissue of the mucous membranes and upper
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respiratory tract.
Ingestion: Harmful if swallowed.
CHRONIC EXPOSURE - CARCINOGEN
Result: This product is or contains a component that has been
reported to be possibly carcinogenic based on its IARC, ACGIH,
NTP, or EPA classification.
Mouse
Route of Application: Oral
Exposure Time: 78W
Result: Tumorigenic:Equivocal tumorigenic agent by RTECS
criteria. Gastrointestinal:Tumors.
Mouse
Route of Application: Intraperitoneal
Exposure Time: 8W
Result: Tumorigenic:Equivocal tumorigenic agent by RTECS
criteria. Lungs, Thorax, or Respiration:Tumors.
Mouse
Route of Application: Oral
Exposure Time: 78W
Result: Tumorigenic:Equivocal tumorigenic agent by RTECS
criteria. Gastrointestinal:Tumors.
IARC CARCINOGEN LIST
Rating: Group 3
CHRONIC EXPOSURE - MUTAGEN
Human
1 MMOL/L
Cell Type: HeLa cell
Unscheduled DNA synthesis
CHRONIC EXPOSURE - TERATOGEN
Species: Rat
Dose: 300 PPM/7H
Route of Application: Inhalation
Exposure Time: (6-15D PREG)
Result: Specific Developmental Abnormalities: Musculoskeletal
system.
Species: Mouse
Dose: 4 GM/KG
Route of Application: Oral
Exposure Time: (7-14D PREG)
Result: Effects on Embryo or Fetus: Fetal death.
CHRONIC EXPOSURE - REPRODUCTIVE HAZARD
Species: Rat
Dose: 1200 MG/KG
Route of Application: Intraperitoneal
Exposure Time: (1-15D PREG)
Result: Effects on Fertility: Post-implantation mortality (e.g.,
dead and/or resorbed implants per total number of implants).
Effects on Embryo or Fetus: Fetotoxicity (except death, e.g.,
stunted fetus). Specific Developmental Abnormalities: Other
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developmental abnormalities.
12 - Ecological Information
No data available.
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
environmental regulations.
14 - Transport Information
RID/ADR
UN#: 1100
Class: 3
PG: I
Proper Shipping Name: Allyl chloride
IMDG
UN#: 1100
Class: 3
PG: I
Subrisk: 6.1
Proper Shipping Name: Allyl chloride
Marine Pollutant: No
Severe Marine Pollutant: No
IATA
UN#: 1100
Class: 3
PG: I
Subrisk: 6.1
Proper Shipping Name: Allyl chloride
Inhalation Packing Group I: No
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
ANNEX I INDEX NUMBER: 602-029-00-X
NOTA: D
INDICATION OF DANGER: F T+ N
Highly Flammable. Very toxic. Dangerous for the environment.
R-PHRASES: 11 26 50
Highly flammable. Very toxic by inhalation. Very toxic to
aquatic organisms.
S-PHRASES: 16 29 33 45 61
Keep away from sources of ignition - no smoking. Do not empty
into drains. Take precautionary measures against static
discharges. In case of accident or if you feel unwell, seek
medical advice immediately (show the label where possible).
Avoid release to the environment. Refer to special
instructions/safety data sheets.
COUNTRY SPECIFIC INFORMATION
Germany
WGK: 2
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SWITZERLAND
SWISS POISON CLASS: 1
NORWAY
Labelling for organic solvents where the package is 1liter or
more.
YL-tall m3/l: 626666
YL-group: 5
Safety phrases: 38 42 210
In case of insufficient ventilation, wear suitable respiratory
equipment. During fumigation/spraying wear suitable respiratory
equipment. Use compressed air- or fresh air line breathing
apparatus in confined spaces.
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2004 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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