SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 09/JUN/2005
Date Updated: 18/MAY/2005
Version 2.1
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name FURAN, 98%
Product Number F19558
Company Sigma-Aldrich Pty. Ltd.
12 Anella Avenue
Castle Hill NSW 2154
Australia
Technical Phone # +61 2 9841 0555 (1800 800 097)
Fax +61 2 9841 0500 (1800 800 096)
Emergency Phone # +44 8701906777 (1800 448 465)
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
FURAN 110-00-9 203-727-3 603-105-00-5
Formula C4H4O
Molecular Weight 68.08 AMU
Synonyms Axole * Divinylene oxide *
1,4-Epoxy-1,3-butadiene * Furfuran * NCI-C56202
* Oxacyclopentadiene * Oxole * RCRA waste number
U124 * Tetrole
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
May cause cancer. Extremely flammable. May form explosive
peroxides. Also harmful by inhalation and if swallowed. Irritating
to skin. Also harmful: danger of serious damage to health by
prolonged exposure if swallowed. Also possible risks of
irreversible effects. Harmful to aquatic organisms, may cause
long-term adverse effects in the aquatic environment.
Carc. Cat.2 Muta. Cat.3
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER SKIN CONTACT
In case of contact, immediately wash skin with soap and copious
amounts of water.
AFTER EYE CONTACT
In case of contact, immediately flush eyes with copious amounts
of water for at least 15 minutes.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Carbon dioxide, dry chemical powder, or appropriate
foam.
Unsuitable: Carbon Dioxide, dry chemical powder, or appropriate
foam. Water can be applied as a spray or fog and if properly
applied is capable of extinguishing the fire by sweeping the
flames off the surface of the burning liquid.
SPECIAL RISKS
Specific Hazard(s): Extremely flammable. Vapor may travel
considerable distance to source of ignition and flash back.
Explosion Hazards: Vapor may travel considerable distance to
source of ignition and flash back. Container explosion may occur
under fire conditions. Forms explosive mixtures in air. Caution:
forms explosive peroxides on prolonged storage.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
SPECIFIC METHOD(S) OF FIRE FIGHTING
Use water spray to cool fire-exposed containers.
6 - Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area. Shut off all sources of ignition. Use nonsparking
tools.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Cover with dry-lime, sand, or soda ash. Place in covered
containers using non-sparking tools and transport outdoors.
Ventilate area and wash spill site after material pickup is
complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe vapor. Avoid
contact with eyes, skin, and clothing. Avoid prolonged or
repeated exposure.
STORAGE
Conditions of Storage: Keep container closed. Keep away from
heat, sparks, and open flame.
SPECIAL REQUIREMENTS: Refrigerate before opening. May develop
pressure. Open carefully.
8 - Exposure Controls / Personal Protection
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ENGINEERING CONTROLS
Safety shower and eye bath. Use nonsparking tools. Mechanical
exhaust required.
GENERAL HYGIENE MEASURES
Remove and wash contaminated clothing promptly. Wash thoroughly
after handling.
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
9 - Physical and Chemical Properties
Appearance Physical State: Clear liquid
Color: Colorless
Property Value At Temperature or Pressure
pH N/A
BP/BP Range 31 - 33 掳C
MP/MP Range N/A
Flash Point -36 掳C Method: closed cup
Flammability N/A
Autoignition Temp 390 掳C
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits Lower: 2.3 %
Upper: 14.3 %
Vapor Pressure 476.674 mmHg 20 掳C
SG/Density 0.936 g/cm3
Partition Coefficient N/A
Viscosity N/A
Vapor Density 2.3 g/l
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility Solubility in Water:Slightly.
Other Solvents: ACETONE, ETHANOL
10 - Stability and Reactivity
STABILITY
Stable: Stable.
Conditions of Instability: May form peroxides of unknown stability.
Materials to Avoid: Oxidizing agents Avoid contact with acid.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
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RTECS NUMBER: LT8524000
ACUTE TOXICITY
LD50
Oral
Rat
300 mg/kg
LC50
Inhalation
Rat
3,398 ppm
1H
Remarks: Sense Organs and Special Senses (Nose, Eye, Ear, and
Taste):Eye:Etosis. Behavioral:Somnolence (general depressed
activity). Lungs, Thorax, or Respiration:Dyspnea.
LD50
Intraperitoneal
Rat
5200 UG/KG
LC50
Inhalation
Mouse
120 mg/m3
1H
Remarks: Lungs, Thorax, or Respiration:Acute pulmonary edema.
Lungs, Thorax, or Respiration:Other changes.
LD50
Intraperitoneal
Mouse
7 MG/KG
SIGNS AND SYMPTOMS OF EXPOSURE
Can cause CNS depression. Prolonged or repeated exposure to skin
causes defatting and dermatitis.
ROUTE OF EXPOSURE
Skin Contact: Causes skin irritation.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: May cause eye irritation.
Inhalation: Material may be irritating to mucous membranes and
upper respiratory tract. Harmful if inhaled.
Ingestion: Harmful if swallowed.
TARGET ORGAN INFORMATION
Liver. G.I. System. Central nervous system.
CHRONIC EXPOSURE - CARCINOGEN
Result: This product is or contains a component that has been
reported to be possibly carcinogenic based on its IARC, ACGIH,
NTP, or EPA classification.
Rat
Route of Application: Oral
Exposure Time: 2Y
Result: Tumorigenic:Carcinogenic by RTECS criteria.
Liver:Tumors. Liver:Angiosarcoma.
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Mouse
Route of Application: Oral
Exposure Time: 2Y
Result: Tumorigenic:Carcinogenic by RTECS criteria. Liver:Tumors.
IARC CARCINOGEN LIST
Rating: Group 2B
CHRONIC EXPOSURE - MUTAGEN
Mouse
1139 MG/L
Cell Type: lymphocyte
Mutation in mammalian somatic cells.
Hamster
184 MMOL/L
Cell Type: ovary
Cytogenetic analysis
CHRONIC EXPOSURE - REPRODUCTIVE HAZARD
Species: Rat
Dose: 3900 MG/KG
Route of Application: Oral
Exposure Time: (13W MALE/13W PRE)
Result: Paternal Effects: Testes, epididymis, sperm duct.
Maternal Effects: Ovaries, fallopian tubes.
12 - Ecological Information
No data available.
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Burn in a chemical incinerator equipped with an
afterburner and scrubber but exert extra care in igniting as this
material is highly flammable. Observe all federal, state, and
local environmental regulations.
14 - Transport Information
RID/ADR
UN#: 2389
Class: 3
PG: I
Proper Shipping Name: Furan
IMDG
UN#: 2389
Class: 3
PG: I
Proper Shipping Name: Furan
Marine Pollutant: No
Severe Marine Pollutant: No
IATA
UN#: 2389
Class: 3
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PG: I
Proper Shipping Name: Furan
Inhalation Packing Group I: No
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
ANNEX I INDEX NUMBER: 603-105-00-5
NOTA: E
INDICATION OF DANGER: F+ T
Extremely Flammable. Toxic.
R-PHRASES: 45 12 19 20/22 38 48/22 68 52/53
May cause cancer. Extremely flammable. May form explosive
peroxides. Also harmful by inhalation and if swallowed.
Irritating to skin. Also harmful: danger of serious damage to
health by prolonged exposure if swallowed. Also possible risks
of irreversible effects. Harmful to aquatic organisms, may
cause long-term adverse effects in the aquatic environment.
S-PHRASES: 53 45 61
Restricted to professional users. Attention - Avoid exposure -
obtain special instructions before use. In case of accident or
if you feel unwell, seek medical advice immediately (show the
label where possible). Avoid release to the environment. Refer
to special instructions/safety data sheets.
COUNTRY SPECIFIC INFORMATION
Germany
WGK: 3 (Self classification)
SWITZERLAND
SWISS POISON CLASS: 3
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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