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MSDS Material Safety Data Sheet
CAS

67-68-5 7647-14-5 75-12-7

File Name: 67-68-5_7647-14-5_75-12.asp

                                                                                                                             Rev.9/2008


Mirus Bio, LLC
505 S. Rosa Rd.
Madison, WI 53719
608.441.2852
www.mirusbio.com



Material Safety Data Sheet

Section I - Product Identification
?br> Product Name Label IT miRNA Labeling Kits, Version 2 ?Reconstitution Solution and Labeling Reagent(s)
Not available separately; Part of MIR 9305, 9325, 9410, 9450, 9510, 9550, 9610, 9650
Part#
Research Laboratory
Product Use

Precautionary Labeling
We are unaware of any hazards with these products when mixed other than those associated with the individual reagents listed below.

Section II - Components
Component CAS# Hazard Weight %
Dimethyl sulfoxide 67-68-5 Irritant. Irritating to eyes, respiratory system and skin. 100
(DMSO) Readily absorbed through skin. In case of contact with
eyes, rinse immediately with plenty of water and seek
medical advice. Do not breathe vapor.
Labeling Reagent Proprietary The hazards of this reagent are not fully characterized. 100
(LR) Potentially harmful ?handle with care. Labeling
reagent covalently modifies nucleic acids. <0.1 when
reconstituted

Section III - Physical Data
(DMSO) clear liquid (DMSO) 1.101
Appearance Specific Gravity
(LR) dried film
(DMSO) 0.42
Boiling Point Vapor Pressure
(DMSO) 189癈
(mm Hg)
Melting Point (DMSO) 18.4癈

Section IV - Fire and Explosion Hazard Data
(DMSO) 63
Flash Point UEL (%)
(DMSO) 85癈
(DMSO) 3.5
Autoignition Temp. LEL (%)
(DMSO) 300癈

Fire Extinguishing Media
Use water spray, carbon dioxide, dry chemical powder or appropriate foam.
Special Fire-Fighting Procedures
Avoid breathing vapors. Use self-contained breathing apparatus. Prevent contact with skin and eyes. Firefighters should
wear proper protective equipment.
Unusual Fire and Explosion Hazards
(DMSO) Emits toxic fumes under fire conditions.
(LR) None known.

Section V - Health Hazard Data
N/A (DMSO) 14500 mg/kg
TLV Oral Rat LD50
N/A N/A
STEL Carcinogenicity
N/A
PEL
Rev.9/2008




Section VI - Reactivity Data
(DMSO) Stable. Not a (DMSO) Acid chorides, phosphorus halides, strong
Stability Incompatibilities
significant hazard in these acids, strong oxidizing agents, strong reducing
quantities. agents.
(DMSO) Excessive heat Decomposition Products (DMSO) Carbon monoxide, carbon dioxide, sulfur
Conditions to
and incompatible materials. oxides.
Avoid

Section VII - Spills and Disposal
Spills
Evacuate area. Wear self-contained breathing apparatus, rubber boots and heavy rubber gloves. Absorb with sand or
vermiculite and place in closed container for disposal. Ventilate area and wash spill site after material pickup is complete.
Disposal
Dispose in accordance with all applicable federal, state, and local regulations.

Section VIII - Protective Equipment
Ventilation
Mechanical ventilation is recommended.
Respiratory Protection
Recommended.
Eye/Skin Protection
Gloves, protective clothing, and eyewear should be worn and safe laboratory practices followed.

Section IX - Storage and Handling
Storage Requirements
(DMSO) Refrigeration. (LR) Freezer storage recommended. Protect from light.


Section X - Transportation
IATA/ICOA
Proper Shipping Name: Combustible Liquid, n.o.s.
UN#: 1993
Class: Combustible Liquid
Packing Group: III
Hazard Label: None
IATA/ICOA: Non Hazardous for Air Transport

The information given above was obtained from reliable sources and we believe it is correct. No warranty is expressed or is implied
regarding the accuracy or completeness of this information. It is the user's responsibility to verify this information and determine its
suitability under their own operating conditions. In no case will Mirus Bio be liable for incidental or consequential damages,
including lost profits.
Rev.9/2008


Mirus Bio, LLC
505 S. Rosa Rd.
Madison, WI 53719
608.441.2852
www.mirusbio.com




Material Safety Data Sheet

Section I - Product Identification
?br> Product Name Label IT miRNA Labeling Kits, Version 2 ?10X STOP Reagent
Not available separately; Part of MIR 9305, 9325, 9410, 9450, 9510, 9550, 9610, 9650
Part#
Research Laboratory
Product Use

Precautionary Labeling
We are unaware of any hazards with these products other than those associated with the individual components of each reagent listed
below.

Section II - Components
Component CAS# Hazard Weight %
Sodium chloride 7647-14-5 Avoid contact with eyes, skin and clothing. 13
Avoid prolonged or repeated exposure. In
case of contact, wash immediately with
copious amounts of water.

Section III - Physical Data
colorless liquid N/A
Appearance Boiling Point

Section IV - Fire and Explosion Hazard Data
Fire Extinguishing Media
Non-combustible. Use water spray to cool fire-exposed containers.
Special Fire-Fighting Procedures
Emits toxic fumes under fire conditions; avoid breathing vapors. Use self-contained breathing apparatus and protective
clothing to prevent contact with skin and eyes.

Section V - Health Hazard Data
N/A N/A
PEL Oral Rat LD50
N/A
Carcinogenicity

Section VI - Reactivity Data
Stable under normal temperatures and pressures. Strong oxidizing agents.
Stability Incompatibilities
Incompatible materials. Not known.
Conditions to Decomposition
Avoid Products

Section VII - Spills and Disposal
Spills
Wear respirator, safety goggles, rubber boots and heavy rubber gloves. Absorb with sand or vermiculite and place in closed
containers for disposal. Ventilate area and wash spill site after material pickup is complete.
Disposal
Dispose in accordance with all applicable federal, state, and local regulations.
Rev.9/2008




Section VIII - Protective Equipment
Respiratory Protection
Wear appropriate NIOSH/MSHA-approved respirator.
Eye/Skin Protection
Wear safety goggles or face shield, chemical resistant gloves and impervious protective clothing. Have a safety shower and
eye bath available.

Section IX - Storage and Handling
Storage Requirements
Keep tightly closed. Store in a cool dry place away from incompatible substances.


The information given above was obtained from reliable sources and we believe it is correct. No warranty is expressed or is implied
regarding the accuracy or completeness of this information. It is the user's responsibility to verify this information and determine its
suitability under their own operating conditions. In no case will Mirus Bio be liable for incidental or consequential damages,
including lost profits.
Rev.9/2008



Mirus Bio, LLC
505 S. Rosa Rd.
Madison, WI 53719
608.441.2852
www.mirusbio.com



Material Safety Data Sheet

Section I - Product Identification
?br> Product Name Label IT miRNA Labeling Kits, Version 2 - 2X Hybridization Buffer
Not available separately; Part of MIR 9305, 9325, 9410, 9450, 9510, 9550, 9610, 9650
Part#
Research Laboratory
Product Use

Precautionary Labeling
We are unaware of any hazards with these products when mixed other than those associated with the individual reagents listed below.

Section II - Components
Component CAS# Hazard Weight %
Formamide 75-12-7 Mists and heated vapors are irritating. Irritant to upper 1-50%
respiratory tract and eyes. May be teratogenic.

Section III - Physical Data
Clear liquid
Appearance
Section IV - Fire and Explosion Hazard Data
Fire Extinguishing Media
Use water spray, carbon dioxide, dry chemical powder or appropriate foam.
Special Fire-Fighting Procedures
Avoid breathing vapors. Use self-contained breathing apparatus. Prevent contact with skin and eyes. Firefighters should
wear proper protective equipment.
Unusual Fire and Explosion Hazards
Moderate, when exposed to heat or flames. Can react with oxidizing materials.

Section V - Health Hazard Data
Overexposure
May be harmful by inhalation, ingestion or skin absorption. Irritant. Danger of serious irreversible effects. May be
teratogenic.
Emergency First Aid
Wash affected area with water. Irrigate eyes for at least 15 minutes. Seek medical attention.

Section VI - Reactivity Data
Stable under recommended Strong oxidizing agents, protect from moisture,
Stability Incompatibilities
storage conditions. acids, and bases.
N/A Decomposition Products Toxic fumes of CO, CO2, nitrogen oxides and
Conditions to
sulfur oxides.
Avoid

Section VII - Spills and Disposal
Spills
Absorb with sand and place in open container for disposal. Ventilate area and wash spill site thoroughly.
Disposal
Dispose in accordance with all applicable federal, state, and local regulations.
Rev.9/2008




Section VIII - Protective Equipment
Ventilation
Not expected to require any special ventilation.
Respiratory Protection
Not expected to require personal respirator usage.
Eye/Skin Protection
Gloves, protective clothing, and eyewear should be worn and safe laboratory practices followed.

Section IX - Storage and Handling
Storage Requirements
Storage: -20癈

The information given above was obtained from reliable sources and we believe it is correct. No warranty is expressed or is implied
regarding the accuracy or completeness of this information. It is the user's responsibility to verify this information and determine its
suitability under their own operating conditions. In no case will Mirus Bio be liable for incidental or consequential damages,
including lost profits.
Rev.9/2008


Mirus Bio, LLC
505 S. Rosa Rd.
Madison, WI 53719
608.441.2852
www.mirusbio.com




Material Safety Data Sheet

Section I - Product Identification
?br> Product Name Label IT miRNA Labeling Kits, Version 2 ?Purification Columns and Buffer Components
Not available separately; Part of MIR 9305, 9325, 9410, 9450, 9510, 9550, 9610, 9650
Part#
Research Laboratory
Product Use

Precautionary Labeling
We are unaware of any hazards with these products other than those associated with the individual components of each reagent listed
below.

Section II - Components
Component CAS# Hazard Weight %
Column Binding Buffer Proprietary Information No hazardous substances in reportable quantities. Proprietary

Column Wash Buffer Proprietary Information No hazardous substances in reportable quantities.

Section III - Physical Data
colorless liquid N/A
Appearance Boiling Point

Section IV - Fire and Explosion Hazard Data
Fire Extinguishing Media
Non-combustible. Use water spray to cool fire-exposed containers.
Special Fire-Fighting Procedures
Emits toxic fumes under fire conditions; avoid breathing vapors. Use self-contained breathing apparatus and protective
clothing to prevent contact with skin and eyes.

Section V - Health Hazard Data
N/A N/A
PEL Oral Rat LD50
N/A
Carcinogenicity

Section VI - Reactivity Data
Stable under normal temperatures and pressures. Strong oxidizing agents.
Stability Incompatibilities
Incompatible materials. Not known.
Conditions to Decomposition
Avoid Products

Section VII - Spills and Disposal
Spills
Wear respirator, safety goggles, rubber boots and heavy rubber gloves. Absorb with sand or vermiculite and place in closed
containers for disposal. Ventilate area and wash spill site after material pickup is complete.
Disposal
Dispose in accordance with all applicable, federal, state, and local regulations.
Rev.9/2008



Section VIII - Protective Equipment
Respiratory Protection
Wear appropriate NIOSH/MSHA-approved respirator.
Eye/Skin Protection
Wear safety goggles or face shield, chemical resistant gloves and impervious protective clothing. Have a safety shower and
eye bath available.

Section IX - Storage and Handling
Storage Requirements
Keep tightly closed. Store in a cool dry place away from incompatible substances.


The information given above was obtained from reliable sources and we believe it is correct. No warranty is expressed or is implied
regarding the accuracy or completeness of this information. It is the user's responsibility to verify this information and determine its
suitability under their own operating conditions. In no case will Mirus Bio be liable for incidental or consequential damages,
including lost profits.

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