Material Safety Data Sheet
Genetron 500
1. CHEMICAL PRODUCT AND COMPANY IDENTIFICATION
PRODUCT NAME: Genetron 500
R-500
OTHER/GENERIC NAMES:
PRODUCT USE: Refrigerant
MANUFACTURER: Honeywell
101 Columbia Road
Box 1053
Morristown, New Jersey 07962-1053
FOR MORE INFORMATION CALL: IN CASE OF EMERGENCY CALL:
(Monday-Friday, 9:00am-5:00pm) (24 Hours/Day, 7 Days/Week)
1-800-522-8001 CHEMTREC: 800-424-9300 or 703-527-3887
2. COMPOSITION/INFORMATION ON INGREDIENTS
INGREDIENT NAME CAS NUMBER WEIGHT %
Dichlorodifluoromethane (CFC-12) 75-71-8 73.8
1,1 Difluoroethane (HFC-152a) 75-37-6 26.2
Trace impurities and additional material names not listed above may also appear in Section 15 toward the end of the MSDS.
These materials may be listed for local "Right-To-Know" compliance and for other reasons.
3. HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW: Colorless, volatile liquid with ethereal and faint sweetish odor.
Non-flammable material. Overexposure may cause dizziness and loss of concentration. At
higher levels, CNS depression and cardiac arrhythmia may result from exposure. Vapors
displace air and can cause asphyxiation in confined spaces. At higher temperatures, (>250癈),
decomposition products may include Hydrochloric Acid (HCl), Hydrofluoric Acid (HF) and
carbonyl halides.
POTENTIAL HEALTH HAZARDS
Irritation would result from a defatting action on tissue. Liquid contact could cause frostbite.
SKIN:
Liquid contact can cause severe irritation and frostbite. Mist may irritate.
EYES:
Genetron 500 is low in acute toxicity in animals even at a concentrations of 4% (40,000ppm).
INHALATION:
However, when oxygen levels in air are reduced to 12?4% by displacement, symptoms of
asphyxiation, loss of coordination, increased pulse rate and deeper respiration will occur. At high
levels, cardiac arrhythmia may occur.
Page 1 of 8
MSDS Number: GTRN-0034
Current Issue Date: January, 2004
MATERIAL SAFETY DATA SHEET
Genetron 500
Ingestion is unlikely because of the low boiling point of the material. Should it occur, discomfort in the
INGESTION:
gastrointestinal tract from rapid evaporation of the material and consequent evolution of gas would result.
Some effects of inhalation and skin exposure would be expected.
DELAYED EFFECTS: None known
Ingredients found on one of the OSHA designated carcinogen lists are listed below.
INGREDIENT NAME NTP STATUS IARC STATUS OSHA LIST
No ingredients listed in this section
4. FIRST AID MEASURES
Promptly flush skin with water until all chemical is removed. If there is evidence of frostbite, bathe (do not rub) with
SKIN:
lukewarm (not hot) water. If water is not available, cover with a clean, soft cloth or similar covering. Get medical
attention if symptoms persist.
Immediately flush eyes with large amounts of water for at least 15 minutes (in case of frostbite water should be
EYES:
lukewarm, not hot) lifting eyelids occasionally to facilitate irrigation. Get medical attention if symptoms persist.
Immediately remove to fresh air. If breathing has stopped, give artificial respiration. Use oxygen as
INHALATION:
required, provided a qualified operator is available. Get medical attention. Do not give epinephrine
(adrenaline).
Ingestion is unlikely because of the physical properties and is not expected to be hazardous. Do not induce
INGESTION:
vomiting unless instructed to do so by a physician.
Because of the possible disturbances of cardiac rhythm, catecholamine drugs, such as
ADVICE TO PHYSICIAN:
epinephrine, should be used with special caution and only in situations of emergency life
support. Treatment of overexposure should be directed at the control of symptoms and the
clinical conditions.
5. FIRE FIGHTING MEASURES
FLAMMABLE PROPERTIES
FLASH POINT: Gas, not applicable per DOT regulations
Not applicable
FLASH POINT METHOD:
AUTOIGNITION TEMPERATURE: Unknown
None*
UPPER FLAME LIMIT (volume % in air):
None*
LOWER FLAME LIMIT (volume % in air):
*Based on ASHRAE Standard 34 with match ignition
Not applicable
FLAME PROPAGATION RATE (solids):
Not applicable
OSHA FLAMMABILITY CLASS:
EXTINGUISHING MEDIA:
Use any standard agent ?choose the one most appropriate for type of surrounding fire (material itself is not flammable)
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MSDS Number: GTRN-0034
Current Issue Date: January, 2004
MATERIAL SAFETY DATA SHEET
Genetron 500
UNUSUAL FIRE AND EXPLOSION HAZARDS:
Contact with certain reactive metals may result in formation of explosive or exothermic reactions under specific conditions
(e.g. very high temperatures and/or appropriate pressures).
This material may become flammable when mixed with air under pressure and exposed to strong ignition sources.
SPECIAL FIRE FIGHTING PRECAUTIONS/INSTRUCTIONS:
Firefighters should wear self-contained, NIOSH-approved breathing apparatus for protection against possible toxic
decomposition products. Proper eye and skin protection should be provided. Use water spray to keep fire-exposed
containers cool.
6. ACCIDENTAL RELEASE MEASURES
IN CASE OF SPILL OR OTHER RELEASE: (Always wear recommended personal protective equipment.)
Evacuate unprotected personnel. Protected personnel should remove ignition sources and shut off leak, if without risk, and
provide ventilation. Unprotected personnel should not return until air has been tested and determined safe, including low-
lying areas.
Spills and releases may have to be reported to Federal and/or local authorities. See Section 15 regarding reporting
requirements.
7. HANDLING AND STORAGE
NORMAL HANDLING: (Always wear recommended personal protective equipment.)
Avoid breathing vapors and liquid contact with eyes, skin or clothing. Do not puncture or drop cylinders, expose them to
open flame or excessive heat. Use authorized cylinders only. Follow standard safety precautions for handling and use of
compressed gas cylinders.
STORAGE RECOMMENDATIONS:
Store in a cool, well-ventilated area of low fire risk and out of direct sunlight. Protect cylinder and its fittings from physical
damage. Storage in subsurface locations should be avoided. Close valve tightly after use and when empty.
8. EXPOSURE CONTROLS/PERSONAL PROTECTION
ENGINEERING CONTROLS:
Provide local ventilation at filling zones and areas where leakage is probable. Mechanical (general) ventilation may be
adequate for other operating and storage areas.
PERSONAL PROTECTIVE EQUIPMENT
SKIN PROTECTION:
Skin contact with refrigerant may cause frostbite. General work clothing and gloves (leather) should provide adequate
protection. If prolonged contact with the liquid or gas is anticipated, insulated gloves constructed of PVA, neoprene or
butyl rubber should be used. Any contaminated clothing should be promptly removed and washed before reuse.
EYE PROTECTION:
For normal conditions, wear safety glasses. Where there is reasonable probability of liquid contact, wear chemical safety
goggles.
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MSDS Number: GTRN-0034
Current Issue Date: January, 2004
MATERIAL SAFETY DATA SHEET
Genetron 500
RESPIRATORY PROTECTION:
None generally required for adequately ventilated work situations. For accidental release or non-ventilated situations, or
release into confined space, where the concentration may be above the PEL of 1,000 ppm, use a self-contained, NIOSH -
approved breathing apparatus or supplied air respirator. For escape: use the former or a NIOSH-approved gas mask
with organic vapor canister.
ADDITIONAL RECOMMENDATIONS:
Where contact with liquid is likely, such as in a spill or leak, impervious boots and clothing should be worn. High dose-
level warning signs are recommended for areas of principle exposure. Provide eyewash stations and quick-drench
shower facilities at convenient locations. For tank cleaning operations, see OSHA regulations, 29 CFR 1910.132 and 29
CFR 1910.133.
EXPOSURE GUIDELINES
INGREDIENT NAME ACGIH TLV OSHA PEL OTHER LIMIT
Dichlorodifluoromethane 1000 ppm TWA 1000 ppm TWA None
(8hr) (8hr)
1,1-Difluoroethane None None **1000 ppm TWA
(8hr)
* = Limit established by Honeywell.
** = Workplace Environmental Exposure Level (AIHA).
*** = Biological Exposure Index (ACGIH).
OTHER EXPOSURE LIMITS FOR POTENTIAL DECOMPOSITION PRODUCTS:
Hydrogen Fluoride: ACGIH TLV = 3 ppm ceiling
9. PHYSICAL AND CHEMICAL PROPERTIES
APPEARANCE: Clear, colorless liquid and vapor
Gas at ambient temperatures
PHYSICAL STATE:
99.31 average
MOLECULAR WEIGHT:
CCl2F2 , CHF2CH3
CHEMICAL FORMULA:
Faint ethereal odor
ODOR:
SPECIFIC GRAVITY (water = 1.0): 1.171 @ 30癈 (86癋)
Unknown
SOLUBILITY IN WATER (weight %):
pH: Neutral
BOILING POINT: -33.5癈 (-28.3癋)
FREEZING POINT: -158癈 (-252.4癋)
VAPOR PRESSURE: 100.1 psia @ 70癋
231.7 psia @ 130癋
4.2
VAPOR DENSITY (air = 1.0):
>1 COMPARED TO: CCl4 = 1
EVAPORATION RATE:
100
% VOLATILES:
Not applicable
FLASH POINT:
(Flash point method and additional flammability data are found in Section 5.)
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MSDS Number: GTRN-0034
Current Issue Date: January, 2004
MATERIAL SAFETY DATA SHEET
Genetron 500
10. STABILITY AND REACTIVITY
NORMALLY STABLE? (CONDITIONS TO AVOID):
The product is stable.
Do not mix with oxygen or air above atmospheric pressure. Any source of high temperature, such as lighted cigarettes,
flames, hot spots or welding may yield toxic and/or corrosive decomposition products.
INCOMPATIBILITIES:
(Under specific conditions: e.g. very high temperatures and/or appropriate pressures) ?Freshly abraded aluminum surfaces
(may cause strong exothermic reaction). Chemically active metals: potassium, calcium, powdered aluminum, magnesium
and zinc.
HAZARDOUS DECOMPOSITION PRODUCTS:
Halogens, halogen acids and possibly carbonyl halides.
HAZARDOUS POLYMERIZATION:
Will not occur.
11. TOXICOLOGICAL INFORMATION
IMMEDIATE (ACUTE) EFFECTS:
Dichlorodifluoromethane
LC50 : 4 hr. (rat) - > 760,000 ppm
Cardiac Sensitization threshold (dog) ?50,000 ppm
10 min EC50 ?254,000 ppm
Difluoroethane
LD50: single dose (rat) ?non-lethal at 1,500 mg/kg
LC50: 2 hr (rat) - ~383,000 ppm. Non-lethal at 200,000 ppm
Cardiac Sensitization NOEL ?>150,000 ppm
DELAYED (SUBCHRONIC AND CHRONIC) EFFECTS:
Dichlorodifluoromethane
Subchronic: NOEL - 10,000 ppm
Difluoroethane
Exposures of rats 6 hrs/day, 5 days/week, for two years at levels up to 25,000 ppm, did not cause chronic toxicity or
carcinogenic response.
OTHER DATA:
Teratology: Not a teratogen
12. ECOLOGICAL INFORMATION
Degradability (BOD): Genetron 500 is a gas at room temperature; therefore, it is unlikely to remain in water.
Octanol Water Partition Coefficient: Unknown
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MSDS Number: GTRN-0034
Current Issue Date: January, 2004
MATERIAL SAFETY DATA SHEET
Genetron 500
13. DISPOSAL CONSIDERATIONS
RCRA
Yes
Is the unused product a RCRA hazardous waste if discarded?
U075
If yes, the RCRA ID number is:
OTHER DISPOSAL CONSIDERATIONS:
Disposal must comply with federal, state, and local disposal or discharge laws. Genetron 500 is subject to U.S.
Environmental Protection Agency Clean Air Act Regulations Section 608 in 40 CFR Part 82 regarding refrigerant recycling.
The information offered here is for the product as shipped. Use and/or alterations to the product such as mixing with other
materials may significantly change the characteristics of the material and alter the RCRA classification and the proper disposal
method.
14. TRANSPORT INFORMATION
US DOT PROPER SHIPPING NAME: Dichlorodifluoromethane and Difluoroethane
US DOT HAZARD CLASS:
Azeotropic Mixture
US DOT HAZARD CLASS: 2.2
US DOT PACKING GROUP: Not applicable
UN2602
US DOT ID NUMBER:
For additional information on shipping regulations affecting this material, contact the information number found in Section 1.
15. REGULATORY INFORMATION
TOXIC SUBSTANCES CONTROL ACT (TSCA)
Components listed on the TSCA inventory
TSCA INVENTORY STATUS:
None
OTHER TSCA ISSUES:
SARA TITLE III/CERCLA
"Reportable Quantities" (RQs) and/or "Threshold Planning Quantities" (TPQs) exist for the following ingredients.
INGREDIENT NAME SARA/CERCLA RQ (lb.) SARA EHS TPQ (lb.)
Dichlorodifluoromethane 5000 None
Spills or releases resulting in the loss of any ingredient at or above its RQ requires immediate notification to the
National Response Center [(800) 424-8802] and to your Local Emergency Planning Committee.
IMMEDIATE
SECTION 311 HAZARD CLASS:
PRESSURE
SARA 313 TOXIC CHEMICALS:
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MSDS Number: GTRN-0034
Current Issue Date: January, 2004
MATERIAL SAFETY DATA SHEET
Genetron 500
The following ingredients are SARA 313 "Toxic Chemicals". CAS numbers and weight percents are found in Section 2.
INGREDIENT NAME COMMENT
Dichlorodifluoromethane None
STATE RIGHT-TO-KNOW
In addition to the ingredients found in Section 2, the following are listed for state right-to-know purposes.
INGREDIENT NAME WEIGHT % COMMENT
No ingredients listed in this section
ADDITIONAL REGULATORY INFORMATION:
Genetron 500 is subject to U.S. Environmental Protection Agency Clean Air Act Regulations at 40 CFR Part 82.
WARNING:
Do not vent to the atmosphere. To comply with provisions of the U.S. Clean Air Act, any residual must be recovered.
Contains Dichlorodifluoromethane (CFC-12), a substance which harms public health and environment by destroying ozone
in the upper atmosphere. Destruction of the ozone layer can lead to increased ultraviolet radiation which, with excess
exposure to sunlight, can lead to an increase in skin cancer and eye cataracts.
Contains Genetron 152a, a greenhouse gas, a substance which may contribute to global warming.
WHMIS CLASSIFICATION (CANADA):
This product has been evaluated in accordance with the hazard criteria of the CPR and the MSDS contains all the information
required by the CPR.
FOREIGN INVENTORY STATUS:
Dichlorodifluoroethane Difluoroethane
Canada ?Listed on DSL EU ?EINECS # 2008661
EU ?EINECS # 2206926 ECL Serial No. 2-276
Canada ?Listed on DSL
16. OTHER INFORMATION
January, 2004
CURRENT ISSUE DATE:
February, 2003
PREVIOUS ISSUE DATE:
CHANGES TO MSDS FROM PREVIOUS ISSUE DATE ARE DUE TO THE FOLLOWING:
Section 3: Revised decomposition products
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MSDS Number: GTRN-0034
Current Issue Date: January, 2004
MATERIAL SAFETY DATA SHEET
Genetron 500
HMIS Classification: Health ?1, Flammability ?1, Reactivity ?0
OTHER INFORMATION:
NFPA Classification: Health ?2, Flammability ?1, Reactivity ?0
ANSI/ASHRAE 34 Safety Group ?A1
Regulatory Standards:
1. OSHA regulations for compressed gases: 29 CFR 1910.101
2. DOT classification per 49 CFR 172.101
3. Clean Air Act Class I Substance
General
a) CGA pamphlet P-1, Safe Handling of Compressed Gases in Containers, 1984, Compressed
Gas Association (1980 Printing)
b) Bretherick, L., Handbook of Reactive Chemical Hazards, 4th ed., 1992, Butterworths,
Boston, MA
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MSDS Number: GTRN-0034
Current Issue Date: January, 2004
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