Analysis

Section 2 - Composition, Information on Ingredients

CAS#	Chemical Name	Percent	EINECS/ELINCS
67-56-1	Methyl alcohol	98.47	200-659-6
1899-02-1	Phenyltrimethylammonium hydroxide	1.53	217-592-3

Section 3 - Hazards Identification

Appearance: clear, colorless liquid. Flash Point: 10 deg C.
Danger! Flammable liquid and vapor. Harmful if inhaled. May be fatal or cause blindness if swallowed. Causes respiratory tract irritation. Causes eye and skin irritation. May be absorbed through intact skin. May cause central nervous system depression. May cause liver, kidney and heart damage. This substance has caused adverse reproductive and fetal effects in animals. Cannot be made non-poisonous.
Target Organs: Kidneys, heart, central nervous system, liver, eyes.


Potential Health Effects
Eye: Produces irritation, characterized by a burning sensation, redness, tearing, inflammation, and possible corneal injury. May cause painful sensitization to light.
Skin: Causes moderate skin irritation. May be absorbed through the skin in harmful amounts. Prolonged and/or repeated contact may cause defatting of the skin and dermatitis.
Ingestion: May be fatal or cause blindness if swallowed. May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause systemic toxicity with acidosis. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure. May cause cardiopulmonary system effects.
Inhalation: Harmful if inhaled. May cause adverse central nervous system effects including headache, convulsions, and possible death. May cause visual impairment and possible permanent blindness. Causes irritation of the mucous membrane.
Chronic: Prolonged or repeated skin contact may cause dermatitis. Chronic inhalation and ingestion may cause effects similar to those of acute inhalation and ingestion. Chronic exposure may cause reproductive disorders and teratogenic effects. Laboratory experiments have resulted in mutagenic effects. Prolonged exposure may cause liver, kidney, and heart damage.

Section 4 - First Aid Measures

Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid imme diately.
Skin: Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
Ingestion: Call a poison control center. If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician: Effects may be delayed. Ethanol may inhibit methanol metabolism.

Section 5 - Fire Fighting Measures

General Information: Containers can build up pressure if exposed to heat and/or fire. As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Water runoff can cause environmental damage. Dike and collect water used to fight fire. Vapors can travel to a source of ignition and flash back. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Water may be ineffective. Material is lighter than water and a fire may be spread by the use of water. Flammable liquid and vapor. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. May be ignited by heat, sparks, and flame.
Extinguishing Media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective. Use agent most appropriate to extinguish fire. For large fires, use water spray, fog or alcohol-resistant foam. Do NOT use straight streams of water.
Flash Point: 10 deg C ( 50.00 deg F)
Autoignition Temperature: 464 deg C ( 867.20 deg F)
Explosion Limits, Lower:6.0
Upper: 36
NFPA Rating: (estimated) Health: 1; Flammability: 3; Instability: 0

Section 6 - Accidental Release Measures

General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Clean up spills immediately, observing precautions in the Protective Equipment section. Use water spray to disperse the gas/vapor. Remove all sources of ignition. Provide ventilation. A vapor suppressing foam may be used to reduce vapors. Water spray may reduce vapor but may not prevent ignition in closed spaces.

Section 7 - Handling and Storage

Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Ground and bond containers when transferring material. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Use only with adequate ventilation. Keep away from heat, sparks and flame.
Storage: Keep away from sources of ignition. Keep refrigerated. (Store below 4癈/39癋.) Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area. Store under an inert atmosphere. Do not store in aluminum or lead containers.

Section 8 - Exposure Controls, Personal Protection

Engineering Controls: Use explosion-proof ventilation equipment. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits

Chemical Name	ACGIH	NIOSH	OSHA - Final PELs
Methyl alcohol	200 ppm TWA; 250 ppm STEL; Skin - potential significant contribution to overall exposure by the cutaneous r oute	200 ppm TWA; 260 mg/m3 TWA 6000 ppm IDLH	200 ppm TWA; 260 mg/m3 TWA
Phenyltrimethylammonium hydroxide	none listed	none listed	none listed

OSHA Vacated PELs: Methyl alcohol: 200 ppm TWA; 260 mg/m3 TWA Phenyltrimethylammonium hydroxide: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear chemical splash goggles.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - Physical and Chemical Properties

Physical State: Liquid
Appearance: clear, colorless
Odor: alcohol-like
pH: Not available.
Vapor Pressure: Not available.
Vapor Density: 1.1
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 64 deg C
Freezing/Melting Point:Not available.
Decomposition Temperature:Not available.
Solubility: Miscible.
Specific Gravity/Density:0.8
Molecular Formula:C9H15NO
Molecular Weight:153.22

Section 10 - Stability and Reactivity

Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: High temperatures, ignition sources.
Incompatibilities with Other Materials: Strong oxidizing agents, strong acids, caustics (e.g. ammonia, ammonium hydroxide, calcium hydroxide, potassium hydroxide, sodium hydroxide), aliphatic amines, isocyanates.
Hazardous Decomposition Products: Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, formaldehyde.
Hazardous Polymerization: Has not been reported

Section 11 - Toxicological Information

RTECS#:      
CAS# 67-56-1: PC1400000      
CAS# 1899-02-1: BT2275000
LD50/LC50:
CAS# 67-56-1:
     Draize test, rabbit, eye: 40 mg Moderate;
     Draize test, rabbit, eye: 100 mg/24H Moderate;
     Draize test, rabbit, skin: 20 mg/24H Moderate;
     Inhalation, rabbit: LC50 = 81000 mg/m3/14H;
     Inhalation, rat: LC50 = 64000 ppm/4H;
     Oral, mouse: LD50 = 7300 mg/kg;
     Oral, rabbit: LD50 = 14200 mg/kg;
     Oral, rat: LD50 = 5600 mg/kg;
     Skin, rabbit: LD50 = 15800 mg/kg;
.

CAS# 1899-02-1:
.

Carcinogenicity:
CAS# 67-56-1: Not listed by ACGIH, IARC, NTP, or CA Prop 65.
CAS# 1899-02-1: Not listed by ACGIH, IARC, NTP, or CA Prop 65.

Epidemiology: No data available.
Teratogenicity: Effects on Newborn: Behaviorial, Oral, rat: TDLo=7500 mg/kg (female 17-19 days after conception). Effects on Embryo or Fetus: Fetotoxicity, Inhalation, rat: TCLo=10000 ppm/7H (female 7-15 days after conception). Specific Developmental Abnormalities: Cardiovascular, Musculoskeletal, Urogenital, Inhalation, rat: TCLo=20000 ppm/7H (7-14 days after conception).
Reproductive Effects: Paternal Effects: Spermatogenesis: Intraperitoneal, mouse TDLo=5 g/kg ( male 5 days pre-mating). Fertility: Oral, rat: TDLo = 35295 mg/kg (female 1-15 days after conception). Paternal Effects: Testes, Epididymis, Sperm duct: Oral, rat: TDLo = 200 ppm/20H (male 78 weeks pre-mating).
Mutagenicity: DNA inhibition: Human Lymphocyte = 300 mmol/L. DNA damage: Oral, rat = 10 umol/kg. Mutation in microorganisms: Mouse Lymphocyte = 7900 mg/L. Cytogenetic analysis: Oral, mouse = 1 gm/kg.
Neurotoxicity: ACGIH cites neuropathy, vision and CNS under TLV Basis.
Other Studies:

Section 12 - Ecological Information

Ecotoxicity: Fish: Fathead Minnow: 29.4 g/L; 96 Hr; LC50 (unspecified)Fish: Goldfish: 250 ppm; 11 Hr; resulted in deathFish: Rainbow trout: 8000 mg/L; 48 Hr; LC50 (unspecified)Fish: Rainbow trout: LC50 = 13-68 mg/L; 96 Hr.; 12 degrees CFish: Fathead Minnow: LC50 = 29400 mg/L; 96 Hr.; 25 degrees C, pH 7.63Fish: Rainbow trout: LC50 = 8000 mg/L; 48 Hr.; UnspecifiedBacteria: Phytobacterium phosphoreum: EC50 = 51,000-320,000 mg/L; 30 minutes; Microtox test No data available.
Environmental: Dangerous to aquatic life in high concentrations. Aquatic toxicity rating: TLm 96>1000 ppm. May be dangerous if it enters water intakes. Methyl alcohol is expected to biodegrade in soil and water very rapidly. This product will show high soil mobility and will be degraded from the ambient atmosphere by the reaction with photochemically produced hyroxyl radicals with an estimated half-life of 17.8 days. Bioconcentration factor for fish (golden ide) < 10. Based on a log Kow of -0.77, the BCF value for methanol can be estimated to be 0.2.
Physical: No information available.
Other: No information available.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series:
CAS# 67-56-1: waste number U154 (Ignitable waste).

Section 14 - Transport Information

	US DOT	Canada TDG
Shipping Name:	METHANOL	METHANOL SOLUTION
Hazard Class:	3	3(6.1)
UN Number:	UN1230	UN1230
Packing Group:	II	II
Additional Info:		FLASHPOINT 12 C

Section 15 - Regulatory Information

US FEDERAL

TSCA
     CAS# 67-56-1 is listed on the TSCA inventory.
     CAS# 1899-02-1 is listed on the TSCA inventory.
Health & Safety Reporting List
     None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
     None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
     None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
     None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
     CAS# 67-56-1: 5000 lb final RQ; 2270 kg final RQ
SARA Section 302 Extremely Hazardous Substances
     None of the chemicals in this product have a TPQ.
SARA Codes
     CAS # 67-56-1: immediate, fire.
     CAS # 1899-02-1: immediate, delayed.
Section 313
     This material contains Methyl alcohol (CAS# 67-56-1, 98.47%),which is subject to the reporting requirements of Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
     CAS# 67-56-1 is listed as a hazardous air pollutant (HAP).

     This material does not contain any Class 1 Ozone depletors.
     This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
     None of the chemicals in this product are listed as Hazardous Substances under the CWA.
     None of the chemicals in this product are listed as Priority Pollutants under the CWA.
     None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
     None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
     CAS# 67-56-1 can be found on the following state right to know lists: California, New Jersey, Pennsylvania, Minnesota, Massachusetts.
     CAS# 1899-02-1 is not present on state lists from CA, PA, MN, MA, FL, or NJ.

California Prop 65

California No Significant Risk Level: None of the chemicals in this product are listed.

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
     T F
Risk Phrases:
     R 11 Highly flammable.
     R 23/24/25 Toxic by inhalation, in contact with skin and if
     swallowed.
     R 39/23/24/25 Toxic : danger of very serious irreversible effects
     through inhalation, in contact with skin and if swallowed.

Safety Phrases:
     S 16 Keep away from sources of ignition - No smoking.
     S 36/37 Wear suitable protective clothing and gloves.
     S 45 In case of accident or if you feel unwell, seek medical advice
     immediately (show the label where possible).
     S 7 Keep container tightly closed.

WGK (Water Danger/Protection)
     CAS# 67-56-1: 1
     CAS# 1899-02-1: No information available.
Canada - DSL/NDSL
     CAS# 67-56-1 is listed on Canada's DSL List.
     CAS# 1899-02-1 is listed on Canada's DSL List.
Canada - WHMIS
     This product has a WHMIS classification of B2, D2A, D2B.
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
     CAS# 67-56-1 is listed on the Canadian Ingredient Disclosure List.

Section 16 - Additional Information

MSDS Creation Date: 9/02/1997
Revision #7 Date: 10/03/2005

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.