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Section 1 - Chemical Product and Company Identification |
MSDS Name: 4-Amino-2-nitrophenol
Catalog Numbers:
AC164230000, AC164230050, AC164230250, AC164231000
Synonyms:
4-Hydroxy-3-nitroaniline; 4-Amino-2-hydroxynitrobenzene.
Company Identification:
Acros Organics N.V.
One Reagent Lane
Fair Lawn, NJ 07410
For information in North America, call: 800-ACROS-01
For emergencies in the US, call CHEMTREC: 800-424-9300
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Section 2 - Composition, Information on Ingredients
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| CAS# |
Chemical Name |
Percent |
EINECS/ELINCS |
| 119-34-6 |
4-Hydroxy-3-nitroaniline |
99 | 204-316-1 |
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Section 3 - Hazards Identification
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EMERGENCY OVERVIEW
Appearance: dark brown crystalline powder.
Warning! Causes eye, skin, and respiratory tract
irritation. Harmful if swallowed. Possible risks of irreversible
effects.
Target Organs: Respiratory system, eyes, skin.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation. May be harmful if absorbed through the skin.
Ingestion:
Harmful if swallowed. May cause irritation of the digestive tract.
Inhalation:
Causes respiratory tract irritation. May be harmful if inhaled.
Chronic:
Possible risk of irreversible effects.
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Section 4 - First Aid Measures
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Eyes:
Immediately flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Immediately flush skin with plenty of water for at
least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Do not induce vomiting. Get medical aid immediately. Call a poison
control center.
Inhalation:
Remove from exposure and move to fresh air immediately. If breathing
is difficult, give oxygen. Get medical aid. Do not use mouth-to-mouth
resuscitation if victim ingested or inhaled the substance; induce
artificial respiration with the aid of a pocket mask equipped with a
one-way valve or other proper respiratory medical device.
Notes to Physician:
Treat symptomatically and supportively.
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Section 5 - Fire Fighting Measures
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General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or appropriate foam.
Flash Point: Not available.
Autoignition Temperature: Not available.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating:
(estimated) Health: 2; Flammability: 1; Instability: 0
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Section 6 - Accidental Release Measures
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General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal
container. Avoid generating dusty conditions. Provide ventilation. Do
not let this chemical enter the environment.
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Section 7 - Handling and Storage
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Handling:
Minimize dust generation and accumulation. Do not get in eyes, on
skin, or on clothing. Do not ingest or inhale. Use with adequate
ventilation.
Storage:
Store in a cool, dry place. Store in a tightly closed container.
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Section 8 - Exposure Controls, Personal Protection
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Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate
ventilation to keep airborne concentrations low.
Exposure Limits
| Chemical Name |
ACGIH |
NIOSH |
OSHA - Final PELs |
| 4-Hydroxy-3-nitroaniline
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none listed
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none listed
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none listed
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OSHA Vacated PELs:
4-Hydroxy-3-nitroaniline:
No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
A respiratory protection program that meets OSHA's 29
CFR 1910.134 and ANSI Z88.2 requirements or European
Standard EN 149 must be followed whenever workplace
conditions warrant respirator use.
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Section 9 - Physical and Chemical Properties
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Physical State: Crystalline powder
Appearance: dark brown
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Vapor Density: Not available.
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point:124 - 128 deg C
Decomposition Temperature:Not available.
Solubility: Not available.
Specific Gravity/Density:Not available.
Molecular Formula:C6H6N2O3
Molecular Weight:154.12
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Section 10 - Stability and Reactivity
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Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, dust generation, excess heat.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong bases, acid chlorides, acid
anhydrides.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.
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Section 11 - Toxicological Information
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RTECS#:
CAS# 119-34-6:
SJ6303000
LD50/LC50:
CAS# 119-34-6:
Draize test,
rabbit, eye: 100 mg/24H Severe;
Oral, mouse: LD50 = 1470 mg/kg;
Oral, rat: LD50 = 1470 mg/kg;
.
Carcinogenicity:
CAS# 119-34-6:
- ACGIH:
Not listed.
- California:
carcinogen, initial date 1/29/99
- NTP:
Not listed.
- IARC:
Not listed.
Epidemiology:
No information available.
Teratogenicity:
No information available.
Reproductive Effects:
No information available.
Mutagenicity:
No information available.
Neurotoxicity:
No information available.
Other Studies:
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Section 12 - Ecological Information
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Ecotoxicity:
Fish: Fathead Minnow: LC50 = 29.9 - 39.4 mg/L; 96 Hr.; Flow-through,
25-27.8 degrees CBacteria: Phytobacterium phosphoreum: EC50 =
38.7 - 43.4 mg/L; 5,15,30 minutes; Microtox test, 15 degrees C
No data available.
Environmental:
TERRESTRIAL FATE: An estimated Koc of 79, based on an experimental
log Kow, indicates that 4-amino-2-nitrophenol will have high
mobility in soil. AQUATIC FATE: 4-Amino-2-nitrophenol is not expected
to volatilize from water surfaces based on an Henry's Law constant of
2.2X10-12 atm-cu m/mole. It may bind strongly to organic matter as
the aromatic amino group is indicated as a highly reactive group
with an affinity for organic materials.
Physical:
ATMOSPHERIC FATE: Based on an estimated vapor pressure of 3.52X10-5
mm Hg at 25 deg C, 4-amino-2-nitrophenol will exist in both the vapor
phase and particulate phase in the ambient atmosphere.
Other:
4-Amino-2-nitrophenol (0.025% w/v) was used as a carbon source for
Nocardia v. when measured for visible growth over a period of 16
days at 30 deg C; growth was slight but noticeable.
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Section 13 - Disposal Considerations
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Chemical waste generators must determine whether a discarded chemical is classified
as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3.
Additionally, waste generators must consult state and local hazardous waste regulations to
ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
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Section 14 - Transport Information
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US DOT |
Canada TDG |
| Shipping Name: |
Not regulated. |
Not regulated. |
| Hazard Class: |
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| UN Number: |
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| Packing Group: |
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Section 15 - Regulatory Information
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US FEDERAL
TSCA
CAS# 119-34-6 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants.
This material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product
are listed as Hazardous Substances under the CWA.
None of the chemicals in this
product are listed as Priority Pollutants under the CWA.
None of the chemicals in this
product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product
are considered highly hazardous by OSHA.
STATE
CAS# 119-34-6 can be found on the
following state right to know lists: Massachusetts.
California Prop 65
The following statement(s) is(are) made in order to comply with
the California Safe Drinking Water Act:
WARNING: This product contains 4-Hydroxy-3-nitroaniline, a chemical
known to the state of California to cause cancer.
California No Significant Risk Level:
None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
XN
Risk Phrases:
R 22 Harmful if swallowed.
R 36/37/38 Irritating to eyes, respiratory system and skin.
R 68 Possible risk of irreversible effects.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately with plenty of
water and seek medical advice.
S 36/37/39 Wear suitable protective clothing, gloves and eye/face pr
otection.
WGK (Water Danger/Protection)
CAS# 119-34-6: No information available.
Canada - DSL/NDSL
CAS# 119-34-6 is listed on Canada's NDSL List.
Canada - WHMIS
This product has a WHMIS classification of D2B.
This product has been classified in accordance with the hazard
criteria of the Controlled Products Regulations and the MSDS
contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
CAS# 119-34-6 is listed on the Canadian Ingredient Disclosure List.
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Section 16 - Additional Information
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MSDS Creation Date: 6/14/1999
Revision #5 Date: 11/14/2007
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no event shall Fisher be liable
for any claims, losses, or damages of any third party or for lost profits
or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if Fisher has been advised of
the possibility of such damages.
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