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Section 1 - Chemical Product and Company Identification |
MSDS Name: epsilon-Caprolactam
Catalog Numbers:
AC108230000, AC108230010, AC108230050, AC220310000, AC220311000, AC403940000
AC403940000, AC403940010, AC403942500
Synonyms:
2-Oxohexamethyleneimine; 6-Aminocaproic acid lactam; 6-Aminohexanoic
acid cyclic lactam; 1-Aza-2-cycloheptanone;
Hexahydro-2H-azepin-2-one; Aminocaproic lactam; Caprolactam.
Company Identification:
Acros Organics N.V.
One Reagent Lane
Fair Lawn, NJ 07410
For information in North America, call: 800-ACROS-01
For emergencies in the US, call CHEMTREC: 800-424-9300
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Section 2 - Composition, Information on Ingredients
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| CAS# |
Chemical Name |
Percent |
EINECS/ELINCS |
| 105-60-2 |
epsilon-Caprolactam |
>99 | 203-313-2 |
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Section 3 - Hazards Identification
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EMERGENCY OVERVIEW
Appearance: white crystals.
Warning! Causes eye, skin, and respiratory tract
irritation. Harmful if inhaled. May be harmful if swallowed or
absorbed through the skin. Hygroscopic (absorbs moisture from the
air).
Target Organs: Central nervous system,
respiratory system, eyes, skin.
Potential Health Effects
Eye:
Causes eye irritation. Vapors cause eye irritation.
Skin:
Causes skin irritation. May cause skin sensitization, an allergic
reaction, which becomes evident upon re-exposure to this material.
May cause dermatitis. May be harmful if absorbed through the skin.
Caprolactam was not a skin irritant to humans when applied as a 5%
aqueous, olive oil, or alcohol solution, and no clear evidence was
found that caprolactam produced dermatitis, although contact
dermatitis was considered a possibility. In 1995, a case of allergic
contact dermatitis from caprolactam exposure was diagnosed in a
textile factory worker where nylon-6 was produced. Caprolactam was
negative in the guinea pig maximization test.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and
diarrhea. May be harmful if swallowed.
Inhalation:
Causes respiratory tract irritation. May cause lung damage. May
cause central nervous system effects such as nausea and headache.
Material has a very low vapor pressure at room temperature, so
inhalation exposures are not expected unless material is heated or
misted.
Inhalation may also cause confusion, cough, and dizziness. In acute
inhalation studies with caprolactam aerosol, rats exhibited shallow
to spasmodic respiration, bloody nasal exudate, severe tremor,
general circulatory congestion, and adverse effects to the lung and
liver.
Chronic:
Chronic inhalation may cause effects similar to those of acute
inhalation. Animal studies indicate that the product may affect the
liver and kidneys.
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Section 4 - First Aid Measures
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Eyes:
In case of contact, immediately flush eyes with plenty of water for a
t least 15 minutes. Get medical aid.
Skin:
In case of contact, flush skin with plenty of water. Remove
contaminated clothing and shoes. Get medical aid if irritation
develops and persists. Wash clothing before reuse.
Ingestion:
If swallowed, do not induce vomiting unless directed to do so by
medical personnel. Never give anything by mouth to an unconscious
person. Get medical aid.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial
respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.
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Section 5 - Fire Fighting Measures
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General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion. This
material in sufficient quantity and reduced particle size is capable
of creating a dust explosion.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or appropriate foam.
Flash Point: 125 deg C ( 257.00 deg F)
Autoignition Temperature: 374 deg C ( 705.20 deg F)
Explosion Limits, Lower:1.40 vol %
Upper: 8.00 vol %
NFPA Rating:
(estimated) Health: 2; Flammability: 1; Instability: 1
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Section 6 - Accidental Release Measures
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General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal
container. Wash area with soap and water. Clean up spills
immediately, observing precautions in the Protective Equipment
section. Avoid generating dusty conditions. Provide ventilation.
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Section 7 - Handling and Storage
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Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Use with adequate ventilation. Minimize dust
generation and accumulation. Avoid breathing vapors from heated
material. Avoid contact with eyes, skin, and clothing. Avoid
breathing dust. Avoid breathing spray or mist.
Storage:
Store in a cool, dry place. Store in a tightly closed container.
Store protected from moisture. Separate from oxidizing materials.
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Section 8 - Exposure Controls, Personal Protection
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Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate general or
local exhaust ventilation to keep airborne concentrations below the
permissible exposure limits.
Exposure Limits
| Chemical Name |
ACGIH |
NIOSH |
OSHA - Final PELs |
| epsilon-Caprolactam
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5 mg/m3 TWA (inhalable fraction and vapor)
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1 mg/m3 TWA (dust); 0.22 ppm TWA (vapor); 1 mg/m3 TWA (vapor)
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none listed
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OSHA Vacated PELs:
epsilon-Caprolactam:
1 mg/m3 TWA (dust); 5 ppm TWA (vapor); 20 mg/m3 TWA (vapor)
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.
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Section 9 - Physical and Chemical Properties
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Physical State: Crystals
Appearance: white
Odor: unpleasant odor
pH: Not available.
Vapor Pressure: 0.0016 mm Hg @ 25 deg C
Vapor Density: 3.01 (air=1)
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 268 deg C @ 760 mm Hg
Freezing/Melting Point:68-71 deg C
Decomposition Temperature:Not available.
Solubility: Soluble.
Specific Gravity/Density:1.02 @ 75癈
Molecular Formula:C6H11NO
Molecular Weight:113.16
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Section 10 - Stability and Reactivity
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Chemical Stability:
Stable under normal temperatures and pressures. Polymerization of
caprolactam is slow and not violent. It does not occur at < 100癈
(212癋).
Conditions to Avoid:
Dust generation, moisture, excess heat.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: May occur.
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Section 11 - Toxicological Information
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RTECS#:
CAS# 105-60-2:
CM3675000
LD50/LC50:
CAS# 105-60-2:
Draize test,
rabbit, eye: 20 mg/24H Moderate;
Draize test, rabbit, skin: 500 mg/24H
Mild;
Inhalation, mouse: LC50 = 450
mg/m3;
Inhalation, rat: LC50 = 300
mg/m3/2H;
Oral, mouse: LD50 = 930
mg/kg;
Oral, rat: LD50 = 1210
mg/kg;
Skin, rabbit: LD50 = 1410
uL/kg;
Skin, rat: LD50 = >2
gm/kg;
.
Carcinogenicity:
CAS# 105-60-2:
Not listed by ACGIH, IARC, NTP, or CA Prop 65.
Epidemiology:
No data available.
Teratogenicity:
No data available.
Reproductive Effects:
No data available.
Mutagenicity:
No data available.
Neurotoxicity:
No data available.
Other Studies:
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Section 12 - Ecological Information
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Ecotoxicity:
No data available.
No information available.
Environmental:
No information available.
Physical:
Octanol/water partition coefficient as log Pow: -0.19.
Other:
Readily biodegradable.
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Section 13 - Disposal Considerations
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Chemical waste generators must determine whether a discarded chemical is classified
as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3.
Additionally, waste generators must consult state and local hazardous waste regulations to
ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
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Section 14 - Transport Information
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US DOT |
Canada TDG |
| Shipping Name: |
Not regulated as a hazardous material |
No information available. |
| Hazard Class: |
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| UN Number: |
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| Packing Group: |
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Section 15 - Regulatory Information
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US FEDERAL
TSCA
CAS# 105-60-2 is listed on the TSCA inventory.
Health & Safety Reporting List
CAS# 105-60-2: Effective 6/1/87, Sunset 6/1/97
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 105-60-2: immediate.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants.
This material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product
are listed as Hazardous Substances under the CWA.
None of the chemicals in this
product are listed as Priority Pollutants under the CWA.
None of the chemicals in this
product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product
are considered highly hazardous by OSHA.
STATE
CAS# 105-60-2 can be found on the
following state right to know lists: California, New Jersey,
Pennsylvania, Minnesota, Massachusetts.
California Prop 65
California No Significant Risk Level:
None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
XN
Risk Phrases:
R 20/22 Harmful by inhalation and if swallowed.
R 36/37/38 Irritating to eyes, respiratory system and skin.
Safety Phrases:
WGK (Water Danger/Protection)
CAS# 105-60-2: 1
Canada - DSL/NDSL
CAS# 105-60-2 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of D2B.
This product has been classified in accordance with the hazard
criteria of the Controlled Products Regulations and the MSDS
contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
CAS# 105-60-2 is listed on the Canadian Ingredient Disclosure List.
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Section 16 - Additional Information
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MSDS Creation Date: 3/16/1998
Revision #5 Date: 3/22/2006
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no event shall Fisher be liable
for any claims, losses, or damages of any third party or for lost profits
or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if Fisher has been advised of
the possibility of such damages.
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