SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 15/NOV/2004
Date Updated: 25/MAR/2004
Version 1.1
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name ISOAMYL ALCOHOL, 98+%
Product Number W205702
Company Sigma-Aldrich Pty, Ltd
Unit 2, 14 Anella Avenue
Castle Hill NSW 1765
Australia
Technical Phone # +61 2 9841 0555
Fax +61 2 9841 0500
Emergency Phone # +61 2 9841 0566
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
3-METHYL-1-BUTANOL, GMP 123-51-3 204-633-5 None
Formula C5H12O
Molecular Weight 88.15 AMU
Synonyms Alcool amilico (Italian) * Alcool isoamylique
(French) * Amylowy alkohol (Polish) *
Fermentation amyl alcohol * Isoamyl alcohol
(ACGIH) * Isoamyl alcohol, primary (OSHA) *
Isoamyl alkohol (Czech) * Iso-amylalkohol
(German) * Isoamylol * Isobutylcarbinol *
Isopentanol * Isopentyl alcohol *
2-Methyl-4-butanol * 3-Methyl butanol *
3-Methylbutan-1-ol * 3-Methyl-1-butanol *
3-Metil-butanolo (Italian)
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Flammable. Harmful if swallowed. Risk of serious damage to eyes.
Irritating to respiratory system and skin.
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER SKIN CONTACT
In case of contact, immediately wash skin with soap and copious
amounts of water.
AFTER EYE CONTACT
In case of contact, immediately flush eyes with copious amounts
of water for at least 15 minutes.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.
SPECIAL RISKS
Specific Hazard(s): Combustible liquid. Emits toxic fumes under
fire conditions. Vapor may travel considerable distance to
source of ignition and flash back.
Explosion Hazards: Vapor may travel considerable distance to
source of ignition and flash back.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear respirator, chemical safety goggles, rubber boots, and
heavy rubber gloves.
METHODS FOR CLEANING UP
Absorb on sand or vermiculite and place in closed containers for
disposal. Ventilate area and wash spill site after material
pickup is complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe vapor. Avoid
contact with eyes, skin, and clothing. Avoid prolonged or
repeated exposure.
STORAGE
Conditions of Storage: Keep tightly closed. Keep away from heat
and open flame.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Mechanical exhaust required. Safety shower and eye bath.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling.
EXPOSURE LIMITS
Country Source Type Value
Poland NDS 200 mg/m3
Poland NDSCh 400 mg/m3
Poland NDSP
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EXPOSURE LIMITS - DENMARK
Source Type Value
OEL TWA 360 mg/m3
100 ppm
EXPOSURE LIMITS - GERMANY
Source Type Value
TRGS 900 OEL 360 mg/m3
100 ppm
Remarks: 4
Remarks: Y
EXPOSURE LIMITS - NORWAY
Source Type Value
OEL 180 mg/m3
50 ppm
EXPOSURE LIMITS - SWITZERLAND
Source Type Value
OEL OEL 360 mg/m3
100 ppm
Remarks: C
EXPOSURE LIMITS - UNITED KINGDOM
Source Type Value
OEL OEL 366 mg/m3
100 ppm
OEL STEL 458 mg/m3
125 ppm
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
9 - Physical and Chemical Properties
Appearance Color: Colorless
Form: Clear liquid
Property Value At Temperature or Pressure
pH N/A
BP/BP Range 131 - 132 掳C
MP/MP Range -117 掳C
Flash Point 43 掳C Method: closed cup
Flammability N/A
Autoignition Temp 340 掳C
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits Lower: 1.2 %
Upper: 9 %
Vapor Pressure 2 mmHg 20 掳C
SG/Density 0.809 g/cm3
Partition Coefficient N/A
Viscosity N/A
Vapor Density > 3 g/l
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
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Solvent Content N/A
Water Content < 0.3 %
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility N/A
10 - Stability and Reactivity
STABILITY
Stable: Stable.
Materials to Avoid: Strong oxidizing agents, Acid chlorides, Acid
anhydrides.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
RTECS NUMBER: EL5425000
ACUTE TOXICITY
LD50
Oral
Rat
1300 mg/kg
Remarks: Liver:Fatty liver degeneration. Kidney, Ureter,
Bladder:Other changes. Blood:Other changes.
LD50
Intravenous
Mouse
234 MG/KG
LD50
Oral
Rabbit
3438 mg/kg
Remarks: Sense Organs and Special Senses (Nose, Eye, Ear, and
Taste):Eye:Corneal damage. Cardiac:Pulse rate. Lungs, Thorax, or
Respiration:Dyspnea.
LD50
Skin
Rabbit
3970 UL/KG
IRRITATION DATA
Eyes
Human
150 ppm
Skin
Rabbit
20 mg
24H
Remarks: Moderate irritation effect
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Eyes
Rabbit
20 mg
24H
Remarks: Moderate irritation effect
SIGNS AND SYMPTOMS OF EXPOSURE
Prolonged contact can cause: Dizziness. Narcotic effect. Nausea,
headache, and vomiting. Coughing, chest pains, difficulty in
breathing. To the best of our knowledge, the chemical, physical,
and toxicological properties have not been thoroughly
investigated.
ROUTE OF EXPOSURE
Skin Contact: Causes skin irritation.
Skin Absorption: Readily absorbed through skin. May be harmful
if absorbed through the skin.
Eye Contact: Causes severe eye irritation.
Inhalation: Material is irritating to mucous membranes and upper
respiratory tract. May be harmful if inhaled.
Ingestion: Harmful if swallowed.
TARGET ORGAN INFORMATION
Central nervous system. Liver. Kidneys.
CHRONIC EXPOSURE - CARCINOGEN
Rat
Route of Application: Oral
Exposure Time: 75W
Result: Tumorigenic:Carcinogenic by RTECS criteria.
Liver:Tumors. Blood:Leukemia
Rat
Route of Application: Subcutaneous
Exposure Time: 85W
Result: Tumorigenic:Carcinogenic by RTECS criteria.
Liver:Tumors. Blood:Leukemia
12 - Ecological Information
No data available.
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. This combustible material may be burned in a
chemical incinerator equipped with an afterburner and scrubber.
Observe all federal, state, and local environmental regulations.
14 - Transport Information
RID/ADR
UN#: 1105
Class: 3
PG: III
Proper Shipping Name: PENTANOLS
IMDG
UN#: 1105
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Class: 3
PG: III
Proper Shipping Name: PENTANOLS
Marine Pollutant: No
Severe Marine Pollutant: No
IATA
UN#: 1105
Class: 3
PG: III
Proper Shipping Name: PENTANOLS
Inhalation Packing Group I: No
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
INDICATION OF DANGER: Xn
Harmful.
R-PHRASES: 10 22 41 37/38
Flammable. Harmful if swallowed. Risk of serious damage to
eyes. Irritating to respiratory system and skin.
S-PHRASES: 16 26 36
Keep away from sources of ignition - no smoking. In case of
contact with eyes, rinse immediately with plenty of water and
seek medical advice. Wear suitable protective clothing.
COUNTRY SPECIFIC INFORMATION
Germany
WGK: 1
SWITZERLAND
SWISS POISON CLASS: 4
16 - Other Information
DISCLAIMER
Caution: for manufacturing, processing, or repacking. This
material is not sterile and has not been pyrogen-tested.
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