SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 14/NOV/2004
Date Updated: 12/MAR/2004
Version 1.3
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name AMMONIUM CHLORIDE, MOLECULAR BIOLOGY
REAGENT
Product Number A9434
Company Sigma-Aldrich Pty, Ltd
Unit 2, 14 Anella Avenue
Castle Hill NSW 1765
Australia
Technical Phone # +61 2 9841 0555
Fax +61 2 9841 0500
Emergency Phone # +61 2 9841 0566
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
AMMONIUM CHLORIDE 12125-02-9 235-186-4 017-014-00-8
Formula NH4Cl
Molecular Weight 53.49 AMU
Synonyms Amchlor * Ammoneric * Ammoniumchlorid (German) *
Ammonium chloride (ACGIH) * Ammonium muriate *
Chlorid amonny (Czech) * Darammon * Sal ammonia
* Sal ammoniac * Salammonite * Salmiac
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Harmful if swallowed. Irritating to eyes.
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER SKIN CONTACT
In case of contact, immediately wash skin with soap and copious
amounts of water.
AFTER EYE CONTACT
In case of contact, immediately flush eyes with copious amounts
of water for at least 15 minutes.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Noncombustible. Use extinguishing media appropriate to
surrounding fire conditions.
SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear respirator, chemical safety goggles, rubber boots, and
heavy rubber gloves.
METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Avoid
raising dust. Ventilate area and wash spill site after material
pickup is complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe dust. Avoid contact
with eyes, skin, and clothing. Avoid prolonged or repeated
exposure.
STORAGE
Conditions of Storage: Keep tightly closed.
SPECIAL REQUIREMENTS: Hygroscopic.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Safety shower and eye bath. Mechanical exhaust required.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling.
EXPOSURE LIMITS
Country Source Type Value
Poland NDS 10 MG/M3
Poland NDSCh 20 MG/M3
Poland NDSP -
EXPOSURE LIMITS - DENMARK
Source Type Value
OEL TWA 10 mg/m3
EXPOSURE LIMITS - NORWAY
Source Type Value
OEL 10 mg/m3
Remarks: 1)
EXPOSURE LIMITS - SWITZERLAND
Source Type Value
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OEL OEL 6 mg/m3
Remarks: A
EXPOSURE LIMITS - UNITED KINGDOM
Source Type Value
OEL OEL 10 mg/m3
OEL STEL 20 mg/m3
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
9 - Physical and Chemical Properties
Appearance Physical State: Solid
Property Value At Temperature or Pressure
pH 4.5 - 5.5 20 掳C Concentration: 50
g/l
BP/BP Range N/A
MP/MP Range 340 掳C
Flash Point N/A
Flammability N/A
Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure 1 mmHg 160.4 掳C
SG/Density 1 g/cm3
Partition Coefficient N/A
Viscosity N/A
Vapor Density 1.9 g/l
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density 500 kg/l
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility Solubility in Water:Soluble.
10 - Stability and Reactivity
STABILITY
Stable: Stable.
Conditions to Avoid: Protect from moisture.
Materials to Avoid: Strong acids, Strong bases, Strong oxidizing
agents.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Ammonia, Hydrogen chloride gas.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
RTECS NUMBER: BP4550000
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ACUTE TOXICITY
LDLO
Oral
Infant
2000 mg/kg
Remarks: Cardiac:Other changes.
LD50
Oral
Rat
1650 mg/kg
LD50
Intramuscular
Rat
30 MG/KG
LD50
Oral
Mouse
1300 mg/kg
LD50
Intraperitoneal
Mouse
485 MG/KG
LD50
Intravenous
Mouse
358 MG/KG
Remarks: Behavioral:Convulsions or effect on seizure threshold.
Behavioral:Coma. Lungs, Thorax, or Respiration:Respiratory
stimulation.
IRRITATION DATA
Eyes
Rabbit
500 mg
24H
Remarks: Mild irritation effect
Eyes
Rabbit
100 mg
Remarks: Severe irritation effect
SIGNS AND SYMPTOMS OF EXPOSURE
To the best of our knowledge, the chemical, physical, and
toxicological properties have not been thoroughly investigated.
ROUTE OF EXPOSURE
Skin Contact: Causes skin irritation.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: Causes severe eye irritation.
Inhalation: May be harmful if inhaled. Material is irritating to
mucous membranes and upper respiratory tract.
Ingestion: Harmful if swallowed.
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CHRONIC EXPOSURE - MUTAGEN
Hamster
400 MG/L
Cell Type: fibroblast
Cytogenetic analysis
12 - Ecological Information
No data available.
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
environmental regulations.
14 - Transport Information
RID/ADR
Non-hazardous for road transport.
IMDG
Non-hazardous for sea transport.
IATA
UN#: 3077
Class: 9
PG: III
Proper Shipping Name: Environmentally hazardous
substance, solid, n.o.s
Inhalation Packing Group I: No
Technical Name: Required
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
ANNEX I INDEX NUMBER: 017-014-00-8
INDICATION OF DANGER: Xn
Harmful.
R-PHRASES: 22 36
Harmful if swallowed. Irritating to eyes.
S-PHRASES: 22
Do not breathe dust.
COUNTRY SPECIFIC INFORMATION
Germany
WGK: 1
SWITZERLAND
SWISS POISON CLASS: 4
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
SIGMA - A9434 www.sigma-aldrich.com Page 5
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2004 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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