The MSDS format adheres to the standards and regulatory requirements
of the United States and may not meet regulatory requirements
in other countries.
DuPont Page 1
Material Safety Data Sheet
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"SUVA" HP80 (R402A)
6003FR Revised 14-OCT-2006
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CHEMICAL PRODUCT/COMPANY IDENTIFICATION
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Material Identification
"SUVA" is a registered trademark of DuPont.
Corporate MSDS Number : DU005613
Company Identification
MANUFACTURER/DISTRIBUTOR
DuPont Fluoroproducts
1007 Market Street
Wilmington, DE 19898
PHONE NUMBERS
Product Information : 1-800-441-7515 (outside the U.S.
302-774-1000)
Transport Emergency : CHEMTREC 1-800-424-9300(outside U.S.
703-527-3887)
Medical Emergency : 1-800-441-3637 (outside the U.S.
302-774-1000)
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COMPOSITION/INFORMATION ON INGREDIENTS
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Components
Material CAS Number %
ETHANE, PENTAFLUORO- (HFC-125) 354-33-6 60
*METHANE, CHLORODIFLUORO- (HCFC-22) 75-45-6 38
PROPANE 74-98-6 2
* Disclosure as a toxic chemical is required under Section 313 of
Title III of the Superfund Amendments and Reauthorization Act of 1986
and 40 CFR part 372.
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HAZARDS IDENTIFICATION
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Potential Health Effects
Inhalation of high concentrations of vapor is harmful and
may cause heart irregularities, unconsciousness, or death.
Intentional misuse or deliberate inhalation may cause death
without warning. Vapor reduces oxygen available for
breathing and is heavier than air. Liquid contact can cause
frostbite.
HUMAN HEALTH EFFECTS:
6003FR DuPont Page 2
Material Safety Data Sheet
(HAZARDS IDENTIFICATION - Continued)
Overexposure to the vapors by inhalation may include
temporary nervous system depression with anesthetic effects
such as dizziness, headache, confusion, incoordination, and
loss of consciousness. Higher exposures to the vapors may
cause temporary alteration of the heart's electrical
activity with irregular pulse, palpitations, or inadequate
circulation. Fatality may occur from gross overexposure.
Skin contact with the liquid may cause frostbite.
Individuals with preexisting diseases of the central nervous
or cardiovascular system may have increased susceptibility
to the toxicity of increased exposures.
Carcinogenicity Information
None of the components present in this material at concentrations
equal to or greater than 0.1% are listed by IARC, NTP, OSHA or ACGIH
as a carcinogen.
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FIRST AID MEASURES
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First Aid
INHALATION
If inhaled, immediately remove to fresh air. Keep person calm.
If not breathing, give artificial respiration. If breathing is
difficult, give oxygen. Call a physician.
SKIN CONTACT
Flush area with lukewarm water. Do not use hot water. If
frostbite has occurred, call a physician.
EYE CONTACT
In case of contact, immediately flush eyes with plenty of water
for at least 15 minutes. Call a physician.
INGESTION
Not a probable route. However, in case of accidental ingestion,
call a physician.
Notes to Physicians
THIS MATERIAL MAY MAKE THE HEART MORE SUSCEPTIBLE TO
ARRHYTHMIAS. Catecholamines such as adrenaline, and other
compounds having similar effects, should be reserved for
emergencies and then used only with special caution.
6003FR DuPont Page 3
Material Safety Data Sheet
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FIRE FIGHTING MEASURES
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Flammable Properties
Flash Point : No flash point
Flammable Limits in Air, % by Volume:
LEL : None per ASTM E681
UEL : None per ASTM E681
Autoignition: Not determined
Fire and Explosion Hazards:
Cylinders may rupture under fire conditions. Decomposition
may occur.
Contact of welding or soldering torch flame with high
concentrations of refrigerant can result in visible changes
in the size and color of torch flames. This flame effect
will only occur in concentrations of product well above the
recommended exposure limit, therefore stop all work and
ventilate to disperse refrigerant vapors from the work area
before using any open flames.
R-402A is not flammable in air at temperatures up to 100
deg C (212 deg F) at atmospheric pressure. However,
mixtures of R-402A with high concentrations of air at
elevated pressure and/or temperature can become combustible
in the presence of an ignition source. R-402A can also
become combustible in an oxygen enriched environment (oxygen
concentrations greater than that in air). Whether a mixture
containing R-402A and air, or R-402A in an oxygen enriched
atmosphere becomes combustible depends on the
inter-relationship of 1) the temperature 2) the pressure,
and 3) the proportion of oxygen in the mixture. In general,
R-402A should not be allowed to exist with air above
atmospheric pressure or at high temperatures; or in an
oxygen enriched environment. For example: R-402A should
NOT be mixed with air under pressure for leak testing or
other purposes.
Experimental data have also been reported which indicate
combustibility of HCFC-22, a component in this blend, in
the presence of chlorine.
Extinguishing Media
As appropriate for combustibles in area.
Fire Fighting Instructions
Keep cylinders cool with water spray or fog. Self-contained
breathing apparatus (SCBA) is required if cylinders rupture
and contents are released under fire conditions. Water
runoff should be contained and neutralized prior to release.
6003FR DuPont Page 4
Material Safety Data Sheet
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ACCIDENTAL RELEASE MEASURES
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Safeguards (Personnel)
NOTE: Review FIRE FIGHTING MEASURES and HANDLING (PERSONNEL)
sections before proceeding with clean-up. Use appropriate
PERSONAL PROTECTIVE EQUIPMENT during clean-up.
Accidental Release Measures
Remove open flames. Use self-contained breathing apparatus
(SCBA) for large spills or releases.
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HANDLING AND STORAGE
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Handling (Personnel)
Avoid breathing vapors. Avoid liquid contact with skin or
eyes. Use with sufficient ventilation to keep employee
exposure below the recommended limits. Avoid prolonged or
repeated exposure. Wash thoroughly after handling.
Storage
Clean, dry area. Do not heat above 52 deg C (125 deg F).
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EXPOSURE CONTROLS/PERSONAL PROTECTION
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Engineering Controls
Refrigerant concentration monitors may be necessary to determine
vapor concentrations in work areas prior to use of torches or
other open flames, or if employees are entering enclosed areas.
Use with sufficient ventilation to keep employee exposure
below the recommended exposure limit. Local exhaust should
be used if large amounts are released. Mechanical
ventilation should be used in low or enclosed places.
Personal Protective Equipment
Impervious gloves should be used to avoid prolonged or
repeated exposure. Chemical splash goggles should be
available for use as needed to prevent eye contact. Under
normal manufacturing conditions, no respiratory protection
is required when using this product. Self-contained
breathing apparatus (SCBA) is required if a large release
occurs.
# Exposure Guidelines
6003FR DuPont Page 5
Material Safety Data Sheet
Applicable Exposure Limits
ETHANE, PENTAFLUORO- (HFC-125)
PEL (OSHA) : None Established
TLV (ACGIH) : None Established
AEL * (DuPont) : 1000 ppm, 8 & 12 Hr. TWA
WEEL (AIHA) : 1000 ppm, 4900 mg/m3, 8 Hr. TWA
METHANE, CHLORODIFLUORO- (HCFC-22)
PEL (OSHA) : None Established
TLV (ACGIH) : 1,000 ppm, 3,540 mg/m3, 8 Hr. TWA, A4
AEL * (DuPont) : None Established
PROPANE
PEL (OSHA) : 1,000 ppm, 1,800 mg/m3, 8 Hr. TWA
AEL * (DuPont) : None Established
* AEL is DuPont's Acceptable Exposure Limit. Where governmentally
imposed occupational exposure limits which are lower than the AEL
are in effect, such limits shall take precedence.
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PHYSICAL AND CHEMICAL PROPERTIES
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Physical Data
Boiling Point : -49.2 C (-56.6 F)
Vapor Pressure : 193.6 psia at 25 deg C (77 deg F)
% Volatiles : 100 WT%
Evaporation Rate : (CCl4 = 1)
Greater than 1
Solubility in Water : Not determined
Odor : Slight ethereal
Form : Liquefied gas
Color : Clear, colorless
Density : 1.152 gm/cc at 25 deg C (77 deg F) -
Liquid
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STABILITY AND REACTIVITY
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Chemical Stability
Material is stable. However, avoid open flames and high
temperatures.
Incompatibility with Other Materials
Incompatible with alkali or alkaline earth metals -
powdered Al, Zn, Be, etc.
6003FR DuPont Page 6
Material Safety Data Sheet
(STABILITY AND REACTIVITY - Continued)
Decomposition
Decomposition products are hazardous. "SUVA" HP80 can be
decomposed by high temperatures (open flames, glowing metal
surfaces, etc.) forming hydrochloric and hydrofluoric acids,
and possibly carbonyl halides. These materials are toxic
and irritating. Contact should be avoided.
Polymerization
Polymerization will not occur.
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TOXICOLOGICAL INFORMATION
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Animal Data
The blend is untested.
ETHANE, PENTAFLUORO
Inhalation 4 hour ALC: > 709,000 ppm in rats
Single, high inhalation exposures caused lethargy, decreased
activity, labored breathing and weight loss. Weak cardiac
sensitization effect, a potentially fatal disturbance of
heart rhythm caused by a heightened sensitivity to the
action of epinephrine. Lowest-Observed-Adverse-Effect-Level
for cardiac sensitization: 100,000 ppm.
Repeated exposure caused: No significant toxicological
effects. No-Observed-Adverse-Effect Level(NOAEL): 50,000 ppm
No animal data are available to define carcinogenic,
developmental or reproductive hazards. In animal testing
this material has not caused developmental toxicity.
HFC-125 does not produce genetic damage in bacterial or
mammalian cell cultures or when tested in animals (not
tested for heritable genetic damage).
METHANE, CHLORODIFLUORO
Inhalation 4-hour LC50: 220,000 ppm in rats
The compound is a skin irritant and a slight eye irritant,
but is not a skin sensitizer in animals.
Effects from single high exposures include central nervous
system depression, anesthesia, rapid breathing, lung
congestion and microscopic liver changes. Cardiac
sensitization occurred in dogs at 50,000 ppm or greater from
the action of exogenous epinephrine.
No toxic effects or abnormal histopathological observations
occurred in rats repeatedly exposed to concentrations
6003FR DuPont Page 7
Material Safety Data Sheet
(TOXICOLOGICAL INFORMATION - Continued)
ranging from 10,000 to 50,000 ppm (v/v). Long-term
exposures to 50,000 ppm (v/v) of vapors produced organ
weight increases and a decrease in body weight gain, but no
increased mortality or adverse hematological effects.
In chronic inhalation studies, HCFC-22, at a concentration
of 50,000 ppm (v/v), produced a small, but statistically
significant increase of late-occurring tumors involving
salivary glands in male rats, but not female rats or male
or female mice. In the same studies, no increased
incidence of tumors was seen in either species at
concentrations of 10,000 ppm or 1000 ppm (v/v).
Long-term administration in corn oil produced no effects
on body weight or mortality.
HCFC-22 was mutagenic in some strains of bacteria in
bacterial cell cultures, but not mammalian cell cultures or
animals. It did not cause heritable genetic damage in
mammals.
A slight, but significant increase in developmental
toxicity was observed at high concentrations (50,000 ppm)
of HCFC-22, a concentration which also produced toxic
effects in the adult animal. Based on these findings,
and other negative developmental studies, HCFC-22 is not
considered a unique hazard to the conceptus. Studies of
the effects of HCFC-22 on male reproductive performance
have been negative. Specific studies to evaluate the
effect on female reproductive performance have not been
conducted, however, limited information obtained from
studies on developmental toxicity do not indicate
adverse effects on female reproductive performance at
concentrations up to 50,000 ppm.
PROPANE
Toxicity in animals occurring only with inhalation exposures
at high concentrations (10% or greater) include cardiac
sensitization, analgesia, irregular respiration and
hypotension. No animal test reports are available to define
carcinogenic, developmental, or reproductive hazards. Tests
in bacteria cell cultures demonstrate no mutagenic activity.
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ECOLOGICAL INFORMATION
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Ecotoxicological Information
Aquatic Toxicity:
HCFC-22
48 hour EC50 - Daphnia magna: 433 mg/L
6003FR DuPont Page 8
Material Safety Data Sheet
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DISPOSAL CONSIDERATIONS
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Waste Disposal
Comply with Federal, State, and local regulations. Reclaim
by distillation or remove to a permitted waste disposal
facility.
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TRANSPORTATION INFORMATION
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Shipping Information
DOT/IMO/IATA
Proper Shipping Name : Liquefied Gas N.O.S.
(Chlorodifluoromethane and
Pentafluoroethane)
Hazard Class : 2.2
UN No. : 3163
Label(s) : Nonflammable Gas
Shipping Containers
Tank Cars.
Cylinders
Ton Tanks
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REGULATORY INFORMATION
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U.S. Federal Regulations
TSCA Inventory Status : Reported/Included.
TITLE III HAZARD CLASSIFICATIONS SECTIONS 311, 312
Acute : Yes
Chronic : No
Fire : No
Reactivity : No
Pressure : Yes
HAZARDOUS CHEMICAL LISTS
SARA Extremely Hazardous Substance: No
CERCLA Hazardous Substance : No
SARA Toxic Chemical - See Components Section
6003FR DuPont Page 9
Material Safety Data Sheet
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OTHER INFORMATION
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NFPA, NPCA-HMIS
NPCA-HMIS Rating
Health :1
Flammability :0
Reactivity :1
Personal Protection rating to be supplied by user depending on use
conditions.
Additional Information
MEDICAL USE: CAUTION: Do not use in medical applications
involving permanent implantation in the human body. For other
medical applications see DuPont CAUTION Bulletin No. H-50102.
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The data in this Material Safety Data Sheet relates only to the
specific material designated herein and does not relate to use in
combination with any other material or in any process.
Responsibility for MSDS : MSDS Coordinator
> : DuPont Fluoroproducts
Address : Wilmington, DE 19898
Telephone : (800) 441-7515
# Indicates updated section.
This information is based upon technical information believed to be
reliable. It is subject to revision as additional knowledge and
experience is gained.
End of MSDS
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