Xylene Page 1 of 5
BBC Biochemical MATERIAL SAFETY DATA SHEET
Section 1. Chemical Product and Company Information
Common Name: Xylene Code: 9910
Supplier: BBC Biochemical MSDS#: 9910
Synonym: Aromatic hydrocarbons Validation Date: 4-17-09
Trade Name: Xylene Print Date: 4-17-09
Material Uses: Clearing Agent Responsible Name: Dr. B
Manufacturer: BBC Biochemical In Case of Emergency: 1-800-424-9300 Chemtrec
PO Box 1320 USA
409 Eleanor Lane 1-202-483-7616 Chemtrec Intrl
Mount Vernon, WA 98273 1-800-635-4477
1-800-635-4477
Section 2. Composition and Information on Ingredients
Name CAS# % by Weight OSHA PEL ACGIH TLV
1) Xylenes 1330-20-7 60-100 100 ppm 100 ppm
2) Ethyl benzene 100-41-4 10-30 100 ppm 50 ppm (skin)
3) Toluene 108-88-3 0-0.5 200 ppm 50 ppm (skin)
4) Cumene 98-82-8 0-0.4 50 ppm 50 ppm
5) Benzene 71-43-2 <0.5 1 ppm 5 ppm
Section 3. Hazards Identification
Physical State and Clear, colorless liquid with aromatic sweet odor.
Appearance
Emergency Overview Note to physician: If more than 2.0 ml per kg has been ingested and vomiting has not occurred,
emesis should be induced with supervision. Keep victim's head below hips to prevent aspiration.
Routes of Entry Not available.
Potential Acute Health Effects
Eyes Liquid is moderately irritating to the eyes. High vapor concentrations may also be irritating.
Skin Liquid is mildly irritating to the skin. Prolonged or repeated contact can result in defatting and drying of
the skin which may result in skin irritation and dermatitis (rash).
Inhalation Vapors may be irritating to the nose, throat, and respiratory tract. High vapor concentrations may cause
central nervous system (CNS) depression.
Ingestion Liquid is moderately toxic and may be harmful if swallowed; may produce CNS depression. Ingestion of
product may result in vomiting; aspiration (breathing) of vomitus into the lungs must be avoided as even
small quantities may result in aspir. pneumontis.
Potential Chronic Health
Effects
Medical Conditions Preexisting eye, skin and respiratory disorders may be aggravated by exposure to this product.
Aggravated by Impaired function from preexisting disorders may be aggravated by exposure to this product.
Overexposure
Overexposure/ Early to moderate CNS depression may be evidenced by giddiness, headache, dizziness, and nausea;
Signs/Symptoms in extreme cases, unconsciousness and death may occur. Aspiration pneumontis may be evidenced by
coughing, labored breathing and cyanosis (bluish skin). In severe cases death may result.
Section 4. First Aid Measures
Eye Contact Immediately flush eyes with plenty of water for at least 15 minutes while holding eyelids open. Get
medical attention.
Skin Contact Remove contaminated clothing/shoes. Flush skin with water. If irritation occurs, get medical attention.
Do not reuse clothing until cleaned.
Inhalation Remove victim to fresh air. If not breathing, give artificial respiration. If breathing is difficult, oxygen
should be administered by qualified personnel. Get medical attention.
Ingestion Do not induce vomiting. If vomiting occurs spontaneously, keep head below hips to prevent aspiration
of liquid into the lungs. Get medical attention.
Notes to Physician Not available.
Section 5. Fire Fighting Measures
Flammability of the Flammable.
Product
Xylene Page 2 of 5
Auto-ignition 986.
Temperature
Flash Points 81癋.
Flammable Limits LEL: 1.00%, UEL: 7.00%
Products of Combustion Not available.
Fire Hazards in Presence Not available.
Of Various Substances
Explosion Hazards in Not available.
Presence of Various
Substances
Fire Fighting Media Use water fog, "alcohol" foam, dry chemical, or CO2. Clear fire area of unprotected personnel. Do
and Instructions not enter confined fire space without full bunker gear, including positive pressure NIOSH approved
SCBA. Cool fire exposed containers with water.
Protective Clothing (Fire)
Special Remarks on Fire Fine mist or spray may be flammable at temperatures below the flash point. Carbon
Hazards monoxide and unidentified organic compounds may be formed during combustion.
Special Remarks on When heated above the flash point this material emits flammable vapors which, when mixed with air,
Explosion Hazards can burn or be explosive.
Section 6. Accidental Release Measures
Small Spill and Leak Ventilate area of leak or spill. Remove all sources of ignition. Clean-up personnel require protective
clothing and respiratory protection from vapors. Only specially trained or qualified personnel should
handle the emergency.
Large Spill and Leak Same as above.
Section 7, Handling and Storage
Handling Empty containers retain product residue and can be dangerous. Do not pressurize, cut weld, braze,
solder, drill, grind, or expose such containers to heat, flame, sparks, static electricity, or other sources
of ignition.
Storage Keep away from heat, sparks, and flame. Surfaces that are hot may ignite liquid product even in the
absence of sparks or flame. Extinguish pilot lights, cigarettes and turn off other sources of ignition
prior to use and until all vapors are gone.
Section 8. Exposure Controls / Personal Protection
Engineering Controls Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety
shower. Provide exhaust ventilation sufficient to keep the airborne concentration of this product below
its exposure limits. Exhaust air may need to be cleaned by scrubbers or filters to reduce
environmental contamination.
Personal Protection
Eyes Use chemical safety goggles and/or full face shield where splashing is possible. Contact lenses
should not be worn when working with this material. Maintain eye wash fountain and quick-drench
facilities in work areas.
Body Where splashing is possible, full chemically resistant protective clothing (e.g., acid suit) and boots are
required.
Respiratory If exposure may or does exceed occupational exposure limits (Sec. 2) use a NIOSH approved
respirator to prevent overexposure. In accord with 29 CFR 1910.134 use either an atmosphere-
supplying respirator or an air-purifying respirator for organic vapors.
Hands Test data indicate the best protection is provided by neoprene, nitrile, and natural rubber gloves.
Feet Impervious footwear is required in areas where splashing is possible.
Personal Protection in See above.
Case of a Large Spill
Product Name Exposure Limits
1)Xylene OSHA PEL 100ppm TWA
2)
3)
Consult Local authorities before acceptable exposure limits.
Section 9. Physical and Chemical Properties
Physical State and Clear, colorless liquid. Odor: Sweet, aromatic.
Appearance
Molecular Weight 106.16 Taste: Not available.
Molecular Formula Not applicable. Color: Colorless.
pH (1%/Water) Essentially neutral.
Boiling/Condensation 279癋
Point
Melting/Freezing Point -54癋 (-48癈)/No data available.
Critical Temperature Not applicable.
Xylene Page 3 of 5
Specific Gravity 0.865-0.875
Vapor Pressure 9 mmHg@20癈.
Vapor Density Heavier than air, 3.7.
Volatility 100% volatile.
Odor Threshold Not applicable.
Evaporation Rate 0.72; slower than ether.
VOC Not available.
Viscosity Not available.
Ionicity (in water) Not available.
Dispersion Properties Not available.
Solubility Solubility negligible in water.
Physical Chemical Not available.
Comments
Section 10. Stability and Reactivity
Stability and Reactivity Stable.
Conditions of Instability Stable under normal conditions. Avoid heat, flame, and other sources of ignition.
Incompatibility with Avoid strong oxidizers. Xylene will attack some forms of plastics, rubber and coatings.
Various Substances
Hazardous Decomposition Carbon monoxide and unidentified organic compounds may be formed during combustion.
Products
Hazardous Will not occur.
Polymerization
Section 11. Toxicological Information
Toxicity to Animals Xylene:
LD50: oral rat=4300 mg/kg.; dermal rabbit >2000 mg/kg
LC50: inhalation rat=6700 ppm for 4 hours
Ethylbenzene:
LD50: oral rat=3500 mg/kg,; dermal rabbit=17.8 mL/kg
LC50: inhalation rat=4000 ppm for 4 hours
Chronic Effects on Xylene (1330-20-7) and ethyl benzene (100-41-4) are listed as toxic chemicals under Section 313 of
Humans SARA Title III. Under Sections 311/312, this product should be reported as an immediate (acute) health
hazard, delayed (chronic) health hazard, and a fire hazard. While there is no evidence that industrially
acceptable levels of toluene vapors (e.g., the TLV) have produced cardiac effects in humans, animal
studies have shown that inhalation of high levels of toluene produced cardiac sensitization. Such
sensitization may cause fatal changes in heart rhythms. This latter effect was shown to be enhanced by
hypoxia or the injection of adrenaline-like agents. Prolonged and repeated exposures to high
concentrations of toluene (mixed solvent) have resulted in hearing loss in laboratory rats. While the
effect of solvents on the human auditory system is uncertain, solvent abusers exposed to high doses of
toluene show signs of hearing loss, and occupational exposure to toluene (mixed solvent) may interact
with noise in causing hearing loss in the work environment. The effects of solvents on human hearing
are uncertain. Solvent abusers and noise interaction with toluene (mixed solvent) in the work
environment may cause signs of hearing loss.
Xylene is not listed as a carcinogen by NTP, IARC, or OSHA and we are not aware of data indicating it
is mutagenic, carcinogenic or a skin sensitizer. Laboratory animals exposed to prolonged and repeated
high doses of xylene by various routes have shown hearing loss and effects in liver, kidneys, lungs,
spleen, heart, blood and adrenals; developmental toxicity studies showed embryolethal/toxic and
teratogenic effects with maternal toxicity. The effects of solvents on human hearing are uncertain.
Solvent abusers and noise interaction with xylene (mixed solvent) in the work environment may cause
signs of hearing loss. Xylene is not listed as a carcinogen by NTP, IARC, or OSHA and we are not
aware of data indicating it is mutagenic, carcinogenic or a skin sensitizer. Laboratory animals exposed
to prolonged and repeated high doses of xylene by various routes have shown hearing loss and effects
in liver, kidneys, lungs, spleen, heart, blood and adrenals; developmental toxicity studies showed
embryolethal/toxic and teratogenic effects with maternal toxicity. The effects of solvents oh human
hearing are uncertain. Solvent abusers and noise interaction with xylene (mixed solvent) in the work
environment may cause signs of hearing loss.
A chronic feeding study in rats with ethyl benzene caused cancer (increase in total malignant tumors).
Developmental toxicity studies in rats with ethyl benzene showed evidence of skeletal and other
malformations at maternally toxic doses; similar effects were not seen in rabbits. Ethyl benzene was not
mutagenic in: Ames test, yeast, drosophila, sister chromatic exchange with cultured human
lymphocytes cells and in vitro cytogenetics assay with CHO cells.
This product contains a chemical or chemicals known to the State of California to cause cancer and/or
reproductive toxicity.
Other Toxic Effects on
Humans
Special Remarks on Not available.
Xylene Page 4 of 5
Toxicity to Animals
Special Remarks on This product may contain benzene (CAS# 71-43-2) at a concentration less than 10 ppm.
Chronic Effects on
Humans
Special Remarks on Not available.
Other Toxic Effects
on Humans
Section 12. Ecological Information
Ecotoxicity Not available.
BODS and COD Not available.
Biodegradable/OEDC Not available.
Mobility Not available.
Toxicity of the Not available.
Products of
Biodegradation
Special Remarks on Not available.
The Products of
Biodegradation
Section 13. Disposal Considerations
Waste Information Whatever cannot be saved for recovery or recycling should be handled as hazardous waste and sent to
a RCRA approved incinerator or disposed in a RCRA approved waste facility. Processing, use or
contamination of this product may change the waste management options. State and local disposal
regulations may differ from federal disposal regulations. Dispose of container and unused contents in
accordance with federal, state and local requirements.
Waste Stream Not available.
Consult your local or regional authorities.
Section 14. Transport Information
DOT Classification Domestic (Land, D.O.T.)
-----------------------
Proper Shipping Name: RQ, XYLENES
Hazard Class: 3
UN/NA: UN1307
Packing Group: III
Information reported for product/size: 398LB
International (Water, I.M.O.)
-----------------------------
Proper Shipping Name: XYLENES
Hazard Class: 3
UN/NA: UN1307
Packing Group: III
Information reported for product/size: 398LB
Marine Pollutant Not available.
Hazardous Substances Not available.
Reportable Quantity
Special Provisions for Chemical Inventory Status - Part 1
Transport Ingredient TSCA EC Japan Australia
m-Xylene (108-38-3) Yes Yes Yes Yes
o-Xylene (95-47-6) Yes Yes Yes Yes
p-Xylene (106-42-3) Yes Yes Yes Yes
Ethyl Benzene (100-41-4) Yes Yes Yes Yes
Chemical Inventory Status - Part 2
Canada
Ingredient Korea DSL NDSL Phil.
m-Xylene (108-38-3) Yes Yes No Yes
o-Xylene (95-47-6) Yes Yes No Yes
p-Xylene (106-42-3) Yes Yes No Yes
Ethyl Benzene (100-41-4) Yes Yes No Yes
Federal, State & International Regulations - Part 1
SARA 302 SARA 313
Ingredient RQ TPQ List Chemical Catg.
m-Xylene (108-38-3) No No Yes No
o-Xylene (95-47-6) No No Yes No
Xylene Page 5 of 5
p-Xylene (106-42-3) No No Yes No
Ethyl Benzene (100-41-4) No No Yes No
Federal, State & International Regulations - Part 2
RCRA TSCA
Ingredient CERCLA 261.33 8(d)
m-Xylene (108-38-3) 1000 No No
o-Xylene (95-47-6) 1000 No No
p-Xylene (106-42-3) 100 No Yes
Ethyl Benzene (100-41-4) 1000 No No
Chemical Weapons Convention: No TSCA 12(b): Yes CDTA: No
SARA 311/312: Acute: Yes Chronic: Yes Fire: Yes Pressure: No
Reactivity: No (Mixture / Liquid)
WARNING:
THIS PRODUCT CONTAINS A CHEMICAL(S) KNOWN TO THE STATE OF CALIFORNIA TO
CAUSE CANCER.
Australian Hazchem Code: 3[Y]
Poison Schedule: None allocated.
WHMIS:
This MSDS has been prepared according to the hazard criteria of the Controlled Products
Regulations (CPR) and the MSDS contains all of the information required by the CPR.
TDG Classification Proper Shipping Name: RQ, XYLENES
Hazard Class: 3
UN/NA: UN1307
Packing Group: III
Information reported for product/size: 398LB
ADR/RID Classification ADR (Europe) Information not available.
IMO/IMDG Classification IMDG Information not available.
ICAO/IATA Classification See IATA Regulations
Proper Shipping Name: XYLENES
Hazard Class: 3
UN/NA: UN1307
Packing Group: III
Information reported for product/size: 398LB
Section 15. Other Information
Label requirements
Fire Hazard
Hazardous Material National Fire
2
Health
3
Information System Protection
3
Fire Hazard Health Reactivity
2 0
(U.S.A.) Association
0
Reactivity
(U.S.A.) Specific Hazard
h
Personal Protection
References
Other Special
Considerations
Notice to Reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above named supplier nor any of its subsidiaries
assumes any liability whatsoever for the accuracy or completeness of the information contained herein.
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