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Section 1 - Chemical Product and Company Identification |
MSDS Name: Dimethyl Fumarate, 99%
Catalog Numbers:
AC222180000, AC222180250, AC222181000
Synonyms:
Fumaric Acid, Dimethyl Ester; Allomaleic Acid Dimethyl Ester.
Company Identification:
Acros Organics N.V.
One Reagent Lane
Fair Lawn, NJ 07410
For information in North America, call: 800-ACROS-01
For emergencies in the US, call CHEMTREC: 800-424-9300
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Section 2 - Composition, Information on Ingredients
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| CAS# |
Chemical Name |
Percent |
EINECS/ELINCS |
| 624-49-7 |
Dimethyl Fumarate |
99 | 210-849-0 |
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Section 3 - Hazards Identification
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EMERGENCY OVERVIEW
Appearance: white crystalline powder.
Warning! Causes severe eye irritation and possible
eye injury. May be harmful if absorbed through the skin. Causes skin
irritation. May cause digestive tract irritation with nausea,
vomiting, and diarrhea. May cause respiratory tract irritation.
Target Organs: None.
Potential Health Effects
Eye:
Contact produces irritation, tearing, and burning pain. Causes
severe eye irritation and possible injury.
Skin:
Causes skin irritation. May be harmful if absorbed through the skin.
May cause reddening of the skin.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and
diarrhea.
Inhalation:
Inhalation of dust may cause respiratory tract irritation.
Chronic:
No information found.
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Section 4 - First Aid Measures
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Eyes:
Get medical aid. Gently lift eyelids and flush continuously with wate
r. Extensive irrigation with water is required (at least 30 minutes).
Skin:
Flush skin with plenty of water for at least 15 minutes while
removing contaminated clothing and shoes. Get medical aid if
irritation develops or persists. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Do NOT induce
vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls
of milk or water. Get medical aid if irritation or symptoms occur.
Inhalation:
Remove from exposure and move to fresh air immediately. If not
breathing, give artificial respiration. If breathing is difficult,
give oxygen. Get medical aid if cough or other symptoms appear.
Notes to Physician:
Treat symptomatically and supportively.
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Section 5 - Fire Fighting Measures
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General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion. Vapors may
be heavier than air. They can spread along the ground and collect
in low or confined areas.
Extinguishing Media:
Use agent most appropriate to extinguish fire. Use water spray, dry
chemical, carbon dioxide, or appropriate foam.
Flash Point: Not available.
Autoignition Temperature: Not available.
Explosion Limits, Lower:N/A
Upper: N/A
NFPA Rating:
(estimated) Health: 1; Flammability: 0; Instability: 0
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Section 6 - Accidental Release Measures
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General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Clean up spills immediately, observing precautions in the Protective
Equipment section. Sweep up, then place into a suitable container for
disposal. Avoid generating dusty conditions. Provide ventilation.
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Section 7 - Handling and Storage
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Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Use only in a well-ventilated area. Avoid contact
with eyes, skin, and clothing. Keep container tightly closed. Avoid
ingestion and inhalation.
Storage:
Store in a cool, dry place. Keep container closed when not in use.
Keep containers tightly closed.
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Section 8 - Exposure Controls, Personal Protection
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Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate general or
local exhaust ventilation to keep airborne concentrations below the
permissible exposure limits.
Exposure Limits
| Chemical Name |
ACGIH |
NIOSH |
OSHA - Final PELs |
| Dimethyl Fumarate
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none listed
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none listed
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none listed
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OSHA Vacated PELs:
Dimethyl Fumarate:
No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes:
Wear safety glasses and chemical goggles if splashing
is possible. Wear appropriate protective eyeglasses or
chemical safety goggles as described by OSHA's eye and
face protection regulations in 29 CFR 1910.133 or
European Standard EN166.
Skin:
Wear appropriate protective gloves and clothing to
prevent skin exposure.
Clothing:
Wear appropriate protective clothing to minimize
contact with skin.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.
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Section 9 - Physical and Chemical Properties
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Physical State: Crystalline powder
Appearance: white
Odor: None reported.
pH: Not available.
Vapor Pressure: Not available.
Vapor Density: 5.0
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 192.0 - 193.0 deg C @ 760.00m
Freezing/Melting Point:103.00 - 104.00 deg C
Decomposition Temperature:Not available.
Solubility: Not available.
Specific Gravity/Density:Not available.
Molecular Formula:C6H8O4
Molecular Weight:144.13
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Section 10 - Stability and Reactivity
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Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, dust generation, excess heat, strong
oxidants.
Incompatibilities with Other Materials:
Acids - bases - oxidizing agents - reducing agents.
Hazardous Decomposition Products:
Carbon monoxide, irritating and toxic fumes and gases, carbon
dioxide.
Hazardous Polymerization: Has not been reported.
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Section 11 - Toxicological Information
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RTECS#:
CAS# 624-49-7:
EM6125000
LD50/LC50:
CAS# 624-49-7:
Draize test,
rabbit, eye: 250 ug/24H Severe;
Draize test, rabbit, skin: 20 mg/24H
Moderate;
Oral, rat: LD50 = 2240
mg/kg;
Skin, rabbit: LD50 = 1250
mg/kg;
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Carcinogenicity:
CAS# 624-49-7:
Not listed by ACGIH, IARC, NTP, or CA Prop 65.
Epidemiology:
No information available.
Teratogenicity:
No information available.
Reproductive Effects:
No information available.
Mutagenicity:
No information available.
Neurotoxicity:
No information available.
Other Studies:
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Section 12 - Ecological Information
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No information available.
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Section 13 - Disposal Considerations
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Chemical waste generators must determine whether a discarded chemical is classified
as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3.
Additionally, waste generators must consult state and local hazardous waste regulations to
ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
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Section 14 - Transport Information
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US DOT |
Canada TDG |
| Shipping Name: |
Not regulated as a hazardous material |
No information available. |
| Hazard Class: |
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| UN Number: |
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| Packing Group: |
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Section 15 - Regulatory Information
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US FEDERAL
TSCA
CAS# 624-49-7 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants.
This material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product
are listed as Hazardous Substances under the CWA.
None of the chemicals in this
product are listed as Priority Pollutants under the CWA.
None of the chemicals in this
product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product
are considered highly hazardous by OSHA.
STATE
CAS# 624-49-7 is not present on
state lists from CA, PA, MN, MA, FL, or NJ.
California Prop 65
California No Significant Risk Level:
None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
XN
Risk Phrases:
R 21 Harmful in contact with skin.
R 36/37/38 Irritating to eyes, respiratory system and skin.
Safety Phrases:
S 36/37/39 Wear suitable protective clothing, gloves and eye/face pr
otection.
WGK (Water Danger/Protection)
CAS# 624-49-7: No information available.
Canada - DSL/NDSL
CAS# 624-49-7 is listed on Canada's DSL List.
Canada - WHMIS
WHMIS: Not available.
This product has been classified in accordance with the hazard
criteria of the Controlled Products Regulations and the MSDS
contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
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Section 16 - Additional Information
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MSDS Creation Date: 6/25/1998
Revision #3 Date: 10/03/2005
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no event shall Fisher be liable
for any claims, losses, or damages of any third party or for lost profits
or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if Fisher has been advised of
the possibility of such damages.
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