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Section 1 - Chemical Product and Company Identification |
MSDS Name: Acrylamide-bis premix 37.5:1 (2.6% concentration)
Catalog Numbers:
AC400280000, AC400280300, AC400281500
Synonyms:
AAM; Acrylamid; Acrylamide Monomer; Acrylic Acid Amide; Acrylic
Amide; Propenoic Acid Amide; 2-Propenamide
Company Identification:
Acros Organics N.V.
One Reagent Lane
Fair Lawn, NJ 07410
For information in North America, call: 800-ACROS-01
For emergencies in the US, call CHEMTREC: 800-424-9300
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Section 2 - Composition, Information on Ingredients
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| CAS# |
Chemical Name |
Percent |
EINECS/ELINCS |
| 79-06-1 |
Acrylamide |
90-95 | 201-173-7 |
| 110-26-9 |
Methylenediacrylamide |
1-5 | 203-750-9 |
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Section 3 - Hazards Identification
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EMERGENCY OVERVIEW
Appearance: Colorless - White Crystalline Powder.
Warning! Acrylamide may cause nervous system
damage. Acrylamide caused cancer and male reproductive disorders in
laboratory animal tests. Acrylamide may polymerize explosively if
heated to 183癋 (84癈). Acrylamide may form explosive dust-air
mixtures. Harmful if swallowed, inhaled, or absorbed through the
skin. Causes eye and skin irritation. May cause allergic skin
reaction. Cancer suspect agent. Light sensitive. Air sensitive.
Target Organs: Eyes, nervous system,
reproductive system, skin.
Potential Health Effects
Eye:
Causes moderate eye irritation.
Skin:
Causes mild skin irritation. May be harmful if absorbed through the
skin. May cause local irritation characterized by blistering and
desquamation of the palms and soles combined with blueness of the
hands and feet.
Ingestion:
Harmful if swallowed. May cause central, peripheral, and autonomic
nervous system effects. Causes digestive tract irritation.
Inhalation:
Causes respiratory tract irritation. May be harmful if inhaled.
Chronic:
May cause cancer in humans. Effects may be delayed.
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Section 4 - First Aid Measures
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Eyes:
Immediately flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid imme
diately.
Skin:
Get medical aid. Immediately flush skin with plenty of water for at
least 15 minutes while removing contaminated clothing and shoes.
Wash clothing before reuse.
Ingestion:
Call a poison control center. If swallowed, do not induce vomiting
unless directed to do so by medical personnel. Never give anything by
mouth to an unconscious person. Get medical aid.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh
air immediately. If breathing is difficult, give oxygen. If
breathing has ceased apply artificial respiration using oxygen and a
suitable mechanical device such as a bag and a mask.
Notes to Physician:
Treat symptomatically and supportively.
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Section 5 - Fire Fighting Measures
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General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion. Use water
spray to keep fire-exposed containers cool. Containers may explode
when heated.
Extinguishing Media:
Do NOT get water inside containers. For small fires, use dry
chemical, carbon dioxide, or water spray. For large fires, use dry
chemical, carbon dioxide, alcohol-resistant foam, or water spray.
Cool containers with flooding quantities of water until well after
fire is out.
Flash Point: 145 deg C ( 293.00 deg F)
Autoignition Temperature: Not available.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating:
(estimated) Health: 2; Flammability: 0; Instability: 0
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Section 6 - Accidental Release Measures
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General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Clean up spills immediately, observing precautions in the Protective
Equipment section. Avoid generating dusty conditions. Provide
ventilation. Place under an inert atmosphere. Do not get water inside
containers. Cover with dry earth, dry sand, or other non-combustible
material followed with plastic sheet to minimize spreading and
contact with water.
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Section 7 - Handling and Storage
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Handling:
Use only in a well-ventilated area. Minimize dust generation and
accumulation. Do not get in eyes, on skin, or on clothing. Keep
container tightly closed. Do not ingest or inhale. Store protected
from light. Handle under an inert atmosphere. Store protected from
air. Wash clothing before reuse. Keep from contact with moist air and
steam.
Storage:
Store in a tightly closed container. Store in a cool, dry,
well-ventilated area away from incompatible substances. Keep
refrigerated. (Store below 4癈/39癋.) Do not expose to air. Store
protected from moisture. Store protected from light.
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Section 8 - Exposure Controls, Personal Protection
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Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate general or
local exhaust ventilation to keep airborne concentrations below the
permissible exposure limits.
Exposure Limits
| Chemical Name |
ACGIH |
NIOSH |
OSHA - Final PELs |
| Acrylamide
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0.03 mg/m3 TWA (inhalable fraction and vapor); Skin - potential significant contribution to overall exposure by the cutaneous r oute
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0.03 mg/m3 TWA 60 mg/m3 IDLH
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0.3 mg/m3 TWA
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| Methylenediacrylamide
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none listed
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none listed
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none listed
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OSHA Vacated PELs:
Acrylamide:
0.03 mg/m3 TWA
Methylenediacrylamide:
No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
A respiratory protection program that meets OSHA's 29
CFR 1910.134 and ANSI Z88.2 requirements or European
Standard EN 149 must be followed whenever workplace
conditions warrant respirator use.
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Section 9 - Physical and Chemical Properties
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Physical State: Crystalline powder
Appearance: Colorless - White Crystalline Powder
Odor: None reported.
pH: Not available.
Vapor Pressure: Not available.
Vapor Density: Not available.
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: Decomposes
Freezing/Melting Point:Decomposes
Decomposition Temperature:145 deg C
Solubility: soluble in water
Specific Gravity/Density:1.1000 g/cm3
Molecular Formula:Not applicable.
Molecular Weight:Not available.
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Section 10 - Stability and Reactivity
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Chemical Stability:
Unstable. May decompose on exposure to moist air or water. May
decompose when exposed to light. May decompose on exposure to air.
Conditions to Avoid:
Incompatible materials, light, dust generation, moisture, exposure to
air, temperatures above 50癈 (122癋), strong oxidants.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong reducing agents, acids, bases,
aluminum, brass, copper, iron, iron salts, heat, moisture, air.
Hazardous Decomposition Products:
Carbon monoxide, oxides of nitrogen, carbon dioxide, ammonia.
Hazardous Polymerization: Will occur.
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Section 11 - Toxicological Information
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RTECS#:
CAS# 79-06-1:
AS3325000
CAS# 110-26-9:
AS3678000
LD50/LC50:
CAS# 79-06-1:
Draize test, rabbit,
eye: 100 mg/24H Moderate;
Draize
test, rabbit, skin: 50 mg/3D Mild;
Draize test, rabbit, skin: 500 mg/24H
Mild;
Oral, mouse: LD50 = 107
mg/kg;
Oral, rabbit: LD50 = 150
mg/kg;
Oral, rat: LD50 = 124
mg/kg;
Skin, rabbit: LD50 = 1680
uL/kg;
Skin, rat: LD50 = 400
mg/kg;
.
CAS# 110-26-9:
Oral, mouse:
LD50 = 380 mg/kg;
Oral, rat: LD50
= 390 mg/kg;
.
Carcinogenicity:
CAS# 79-06-1:
- ACGIH:
A3 - Confirmed animal carcinogen with unknown relevance to humans
- California:
carcinogen, initial date 1/1/90
- NTP:
Suspect carcinogen
- IARC:
Group 2A carcinogen
CAS# 110-26-9:
Not listed by ACGIH, IARC, NTP, or CA Prop 65.
Epidemiology:
No information available.
Teratogenicity:
CAS# 79-06-9 Carcinogenic Effects: Oral, rat TDLo = 1456
mg/kg/2Y-C.; Oral, mouse: TDLo = 300 mg/kg/2W-I.;
Neoplastic Effects: Intraperitoneal, mouse: TDLo = 24
mg.kg/8W-I.; Intraperitoneal, mouse: TD = 72 mg/kg/8W-I.
Reproductive Effects:
CAS# 110-26-9 Paternal effects: testes/sperm
duct/epididymis by orl-mus TDLo = 3208 mg/kg (16 D male).;
Maternal Effects: orl-mus TDLo = 360 mg/kg (male 16 days,
pre-mating).; Paternal Effects: orl-mus TDLo = 50 mg/kg
(male 1 day, pre-mating).; Fertility: Pre-implantation
mortality- intraperitoneal, mouse TDLo = 225 mg/kg (male 1
day, pre-mating).CAS# 79-06-1 Oral, rat TDLo = 200 mg/kg
(7-16D preg).; Oral, rat LD 1456 mg/kg/2Y-C.
Mutagenicity:
CAS# 79-06-9 Unscheduled DNA synthesis: Human mammary gland
= 1mmol/L.; Micronucleus Test: Intraperitoneal, rat = 100
mg/kg.; DNA Inhibition: rat cells = 1mmol/L.; Sister
chromatid exchange: oral, rat = 600 mg/kg/10D
(Continuous).; Dominant lethal test: oral, rat = 150
mg/kg/5D (Continuous.
Neurotoxicity:
No information available.
Other Studies:
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Section 12 - Ecological Information
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No information available.
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Section 13 - Disposal Considerations
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Chemical waste generators must determine whether a discarded chemical is classified
as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3.
Additionally, waste generators must consult state and local hazardous waste regulations to
ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series:
CAS# 79-06-1: waste
number U007.
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Section 14 - Transport Information
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| |
US DOT |
Canada TDG |
| Shipping Name: |
ACRYLAMIDE, SOLID, MIXTURE |
ACRYLAMIDE, SOLID, MIXTURE |
| Hazard Class: |
6.1 |
6.1 |
| UN Number: |
UN2074 |
UN2074 |
| Packing Group: |
III |
III |
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Section 15 - Regulatory Information
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US FEDERAL
TSCA
CAS# 79-06-1 is listed on the TSCA inventory.
CAS# 110-26-9 is listed on the TSCA inventory.
Health & Safety Reporting List
CAS# 79-06-1: Effective 10/4/82, Sunset 10/4/92
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
CAS# 79-06-1: 5000 lb final RQ; 2270 kg final RQ
SARA Section 302 Extremely Hazardous Substances
CAS# 79-06-1: 1000 lb lower threshold TPQ; 10000 lb upper threshold TP
Q
SARA Codes
CAS # 79-06-1: immediate, delayed, sudden release of pressure, reactive.
CAS # 110-26-9: immediate, delayed, reactive.
Section 313
This material contains Acrylamide
(CAS# 79-06-1, 90-95%),which is subject to the reporting requirements
of Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
CAS# 79-06-1 is listed as a hazardous air pollutant (HAP).
This material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product
are listed as Hazardous Substances under the CWA.
None of the chemicals in this
product are listed as Priority Pollutants under the CWA.
None of the chemicals in this
product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product
are considered highly hazardous by OSHA.
STATE
CAS# 79-06-1 can be found on the
following state right to know lists: California, New Jersey,
Pennsylvania, Minnesota, Massachusetts.
CAS# 110-26-9 is not present on
state lists from CA, PA, MN, MA, FL, or NJ.
California Prop 65
The following statement(s) is(are) made in order to comply with
the California Safe Drinking Water Act:
WARNING: This product contains Acrylamide, a chemical known to the
state of California to cause cancer.
California No Significant Risk Level:
CAS# 79-06-1: 0.2 鎔/day NSRL
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
T
Risk Phrases:
R 20/21 Harmful by inhalation and in contact with skin.
R 25 Toxic if swallowed.
R 36/38 Irritating to eyes and skin.
R 43 May cause sensitization by skin contact.
R 45 May cause cancer.
R 46 May cause heritable genetic damage.
R 48/23/24/25 Toxic : danger of serious damage to health by
prolonged exposure through inhalation, contact with skin and if
swallowed.
R 62 Possible risk of impaired fertility.
Safety Phrases:
S 45 In case of accident or if you feel unwell, seek medical advice
immediately (show the label where possible).
S 53 Avoid exposure - obtain special instructions before use.
WGK (Water Danger/Protection)
CAS# 79-06-1: 3
CAS# 110-26-9: 2
Canada - DSL/NDSL
CAS# 79-06-1 is listed on Canada's DSL List.
CAS# 110-26-9 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of D1B, D2B.
This product has been classified in accordance with the hazard
criteria of the Controlled Products Regulations and the MSDS
contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
CAS# 79-06-1 is listed on the Canadian Ingredient Disclosure List.
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Section 16 - Additional Information
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MSDS Creation Date: 11/04/1998
Revision #6 Date: 11/08/2007
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no event shall Fisher be liable
for any claims, losses, or damages of any third party or for lost profits
or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if Fisher has been advised of
the possibility of such damages.
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