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Search   
MSDS  
:
 m-Phenylenediamine
CAS  
:
 108-45-2
SYNONYMS  
:
 1,3-Diaminobenzene.

Section 1 - Chemical Product and Company Identification
MSDS Name: m-Phenylenediamine
Catalog Numbers: AC130560000, AC130560010, AC130560250, AC130562500, AC130565000
Synonyms:
1,3-Diaminobenzene.
Company Identification:

              Acros Organics N.V.
              One Reagent Lane
              Fair Lawn, NJ 07410
For information in North America, call: 800-ACROS-01
For emergencies in the US, call CHEMTREC: 800-424-9300

Section 2 - Composition, Information on Ingredients

CAS# Chemical Name Percent EINECS/ELINCS
108-45-2 m-Phenylenediamine 99+ 203-584-7

Section 3 - Hazards Identification

EMERGENCY OVERVIEW

Appearance: brown-gray solid.
Danger! Toxic if swallowed, inhaled or absorbed through the skin. Causes eye irritation. Possible risks of irreversible effects. Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. May cause sensitization by skin contact.
Target Organs: Kidneys, central nervous system.


Potential Health Effects
Eye: Causes eye irritation.
Skin: May cause skin irritation. Toxic in contact with skin. May cause sensitization by skin contact.
Ingestion: May cause irritation of the digestive tract. Toxic if swallowed.
Inhalation: May cause respiratory tract irritation. Toxic if inhaled.
Chronic: Adverse reproductive effects have been reported in animals. Laboratory experiments have resulted in mutagenic effects. Repeated or prolonged exposure may cause allergic reactions in sensitive individuals. May cause kidney damage. Exposure to high concentrations may cause central nervous system depression. Animal studies have reported the development of tumors. Possible risk of irreversible effects.

Section 4 - First Aid Measures


Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid imme diately.
Skin: Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion: POISON material. If swallowed, get medical aid immediately. Only induce vomiting if directed to do so by medical personnel. Never give anything by mouth to an unconscious person.
Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Do not use mouth-to-mouth resuscitation if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device.
Notes to Physician: Treat symptomatically and supportively.

Section 5 - Fire Fighting Measures


General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors or dust may form explosive mixture with air.
Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam.
Flash Point: 175 deg C ( 347.00 deg F)
Autoignition Temperature: 530 deg C ( 986.00 deg F)
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 3; Flammability: 1; Instability: 1

Section 6 - Accidental Release Measures


General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Wear a self contained breathing apparatus and appropriate personal protection. (See Exposure Controls, Personal Protection section). Avoid generating dusty conditions. Provide ventilation. Evacuate unnecessary personnel. Do not let this chemical enter the environment.

Section 7 - Handling and Storage


Handling: Minimize dust generation and accumulation. Do not get in eyes, on skin, or on clothing. Do not ingest or inhale. Use only in a chemical fume hood.
Storage: Store in a cool, dry place. Store in a tightly closed container. Store protected from light. Store under nitrogen.

Section 8 - Exposure Controls, Personal Protection


Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use only under a chemical fume hood.
Exposure Limits
Chemical Name ACGIH NIOSH OSHA - Final PELs
m-Phenylenediamine 0.1 mg/m3 TWA none listed none listed

OSHA Vacated PELs: m-Phenylenediamine: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

Section 9 - Physical and Chemical Properties


Physical State: Solid
Appearance: yellow - light tan - brown-gray
Odor: amine-like
pH: 8 (100g/L aq.sol.)
Vapor Pressure: 1.3 hPa @ 100 deg C
Vapor Density: Not available.
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 282 - 284 deg C @ 760 mmHg
Freezing/Melting Point:63 - 65 deg C
Decomposition Temperature:Not available.
Solubility: 350 g/L (25C)
Specific Gravity/Density:Not available.
Molecular Formula:C6H8N2
Molecular Weight:108.14

Section 10 - Stability and Reactivity


Chemical Stability: Darkens on exposure to light and air. Air sensitive. Light sensitive.
Conditions to Avoid: Incompatible materials, light, dust generation, exposure to air, excess heat.
Incompatibilities with Other Materials: Strong oxidizing agents, acids, acid chlorides, acid anhydrides, chloroformates.
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.

Section 11 - Toxicological Information


RTECS#:      
CAS# 108-45-2: SS7700000
LD50/LC50:
CAS# 108-45-2:
     Draize test, rabbit, eye: 100 uL Severe;
     Oral, mouse: LD50 = 67700 ug/kg;
     Oral, rabbit: LD50 = 437 mg/kg;
     Oral, rat: LD50 = 280 mg/kg;
.

Carcinogenicity:
CAS# 108-45-2: Not listed by ACGIH, IARC, NTP, or CA Prop 65.

Epidemiology: Tumorigenic effects have been reported in experimental animals.
Teratogenicity: Teratogenic effects have occurred in experimental animals.
Reproductive Effects: Adverse reproductive effects have occurred in experimental animals.
Mutagenicity: Mutagenic effects have occurred in experimental animals.
Neurotoxicity: No information found
Other Studies:

Section 12 - Ecological Information


Ecotoxicity: Fish: Fathead Minnow: LC50 = 0.028 mg/L; 96 Hr.; UnspecifiedFish: Rainbow trout: LC50 =3.9 mg/L; 96 Hr.; UnspecifiedFish: Goldfish: LC50 =5.74 mg/L; 48 Hr.; UnspecifiedWater flea Daphnia: EC50 = 3.9 mg/L; 48 Hr.; Unspecified The product is chemically identically to the natural amino acid L-Serine and can therefore be degraded microbiologically.
Environmental: An estimated BCF value of 0.33 was calculated for 1,3-benzenediamine, using an estimated log Kow of -0.33 and a recommended regression-derived equation. BCF values of 1.3 to 4.6 and <1.6 to 24 were measured for 1,3-benzenediamine in carp at 2 and 0.2 mg/l, respectively. According to a classification scheme, these BCF values suggest that bioconcentration in acquatic organisms is low.
Physical: No information found.
Other: The Koc of 1,3-benzenediamine is estimated as approximately 16, using a measured log Kow of -0.33 and a regression-derived equation. According to a recommended classification scheme, this estimated Koc value suggests that 1,3-benzenediamine is expected to have very high mobility in soil. However, anilines are expected to bind strongly to humus or organic matter in soils due to the high reactivity of the aromatic amino group; therefore, mobility may be much lower in some soils.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.

Section 14 - Transport Information

US DOT Canada TDG
Shipping Name: PHENYLENEDIAMINES PHENYLENEDIAMINES
Hazard Class: 6.1 6.1
UN Number: UN1673 UN1673
Packing Group: III III

Section 15 - Regulatory Information

US FEDERAL

TSCA
     CAS# 108-45-2 is listed on the TSCA inventory.
Health & Safety Reporting List
     None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
     CAS# 108-45-2: 40 CFR 799.3300
Section 12b
     None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
     None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
     None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
     None of the chemicals in this product have a TPQ.
Section 313
     This material contains m-Phenylenediamine (CAS# 108-45-2, 99+%),which is subject to the reporting requirements of Section 313 of SARA Title III and 40 CFR
Clean Air Act:
     This material does not contain any hazardous air pollutants.
     This material does not contain any Class 1 Ozone depletors.
     This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
     None of the chemicals in this product are listed as Hazardous Substances under the CWA.
     None of the chemicals in this product are listed as Priority Pollutants under the CWA.
     None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
     None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
     CAS# 108-45-2 can be found on the following state right to know lists: New Jersey, Minnesota, Massachusetts.

California Prop 65

California No Significant Risk Level: None of the chemicals in this product are listed.

European/International Regulations

European Labeling in Accordance with EC Directives
Hazard Symbols:
     T N
Risk Phrases:

     R 23/24/25 Toxic by inhalation, in contact with skin and if
     swallowed.
     R 36 Irritating to eyes.
     R 43 May cause sensitization by skin contact.
     R 50/53 Very toxic to aquatic organisms, may cause long-term
     adverse effects in the aquatic environment.
     R 68 Possible risk of irreversible effects.

Safety Phrases:

     S 36/37 Wear suitable protective clothing and gloves.
     S 45 In case of accident or if you feel unwell, seek medical advice
     immediately (show the label where possible).
     S 60 This material and its container must be disposed of as hazardou
     s waste.
     S 28A After contact with skin, wash immediately with plenty of water
     .
     S 61 Avoid release to the environment. Refer to special instructions
     /safety data sheets.

WGK (Water Danger/Protection)

     CAS# 108-45-2: 2
Canada - DSL/NDSL
     CAS# 108-45-2 is listed on Canada's DSL List.
Canada - WHMIS
     This product has a WHMIS classification of D1B, D2B.
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
     CAS# 108-45-2 is listed on the Canadian Ingredient Disclosure List.

Section 16 - Additional Information

MSDS Creation Date: 5/19/1999
Revision #7 Date: 2/19/2008

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.

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