MATERIAL SAFETY DATA SHEET
Section 1: PRODUCT AND COMPANY IDENTIFICATION
Research Organics, Inc. Company Phone Number: 1-800-321-0570
4353 East 49th Street Monday-Friday, 8:00 a.m. ?4:30 p.m. EDT
Cleveland, Ohio 44125 USA Telephone Numbers ?24 Hour Emergency Assistance
INFOTRAC 1-800-535-5053 [USA]
01-352-323-3500
PRODUCT NAME: MES
RES0113M
PART NUMBER:
CAS NUMBER: 145224-94-8
SYNONYMS: MES, monohydrate;
2-(N-Morpholino)ethanesulfonic acid, monohydrate
2-(4-Morpholino)ethanesulfonic acid, monohydrate
ISSUE DATE: 04/25/06
SUPERSEDES DATE: 10/18/05
REVISION: B01
Section 2: HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Appearance/Odor: White powder with no odor
CAUTION!
MAY BE IRRITATING TO SKIN, EYES, AND UPPER RESPIRATORY TRACT.
MAY BE HARMFUL IF SWALLOWED, INHALED, OR ABSORBED THROUGH SKIN.
THE TOXICOLOGICAL PROPERTIES OF THIS MATERIAL HAVE NOT BEEN FULLY
INVESTIGATED.
Potential Health Effects: See Section 11 for more information
Routes of Exposure: Eye contact, skin contact, inhalation and ingestion
Eye: Direct contact may cause irritation, redness, tearing, and blurred vision.
Skin: Prolonged exposure may cause minor skin irritation. May be absorbed through
the skin.
Ingestion: If ingested, this material may cause irritation to the mouth, throat and
gastrointestinal tract.
May be harmful if swallowed.
Inhalation: This material may cause irritation to the respiratory tract including injury or
illness.
Medical Conditions Aggravated By Exposure:
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MATERIAL SAFETY DATA SHEET
May cause more significant skin or respiratory irritation in people have pre-
existing conditions.
Target Organs: ND
This product does not contain any carcinogens or potential carcinogens as listed by OSHA, IARC or NTP.
This material is considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200).
Potential Environmental Effects: See Section 12 for more information
Not considered to have environmental effects to fish.
Section 3: COMPOSITION/INFORMATION ON INGREDIENTS
Component CAS # % by Wt.
MES 145224-94-8 >= 99%
Section 4: FIRST AID MEASURES
Eye Contact: Flush immediately with large amounts of water for at least 20 minutes. Eyelids should be held
away from the eyeball to ensure thorough rinsing. Do not allow victim to rub the affected eye(s).
Get medical attention if irritation persists.
Skin Contact: Immediately flush skin with plenty of water, for at least 15 minutes, while removing
contaminated clothing and shoes. Contaminated clothing must be laundered before reuse. Get
medical attention if irritation develops or persists.
Inhalation: Safety remove victim to fresh air. If not breathing, then institute artificial respiration/rescue
breathing. If breathing is difficult, ensure clear airway and give oxygen. Get medical attention,
if difficult breathing, irritation develops or persists.
Ingestion: If swallowed, wash out mouth with water provided person is conscious. Never give anything by
mouth to an unconscious person. Get medical attention.
Note to Physicians: ND
Section 5: FIRE FIGHTING MEASURES
Suitable Extinguishing Media: Water Spray, Dry Chemical, Alcohol or All-Purpose Foam or Carbon Dioxide.
Use extinguisher media appropriate for surrounding fire.
Unsuitable Extinguishing Media: None known to manufacturer.
Production of Combustion: May produce CO, CO2, NO x, and/or SO x.
Protection of Firefighters: As in any fire, wear self-contained breathing apparatus pressure-demand,
(MSHA/NIOSH approved or equivalent) and full protective gear. Evacuate the area and fight fire from a safe
distance.
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Revision: B01; 04/25/06 Replaces Sheet Date: 10/18/04
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MATERIAL SAFETY DATA SHEET
Unusual Fire and Explosion Hazards: None
Section 6: ACCIDENTAL RELEASE MEASURES
Personal Precautions: Use personal protection recommended in Section 8
Environmental Precautions: Do not flush to sewer. Avoid runoff into storm sewers and ditches which lead to
waterways.
Methods for Containment: If product is released to the environment, take immediate steps to stop the release.
Caution should be exercised regarding personnel safety and exposure to the released product.
Vacuum or sweep up material and place in a disposal container.
Methods for Clean-Up: Clean up spills immediately under qualified supervision observing precautions in
Protective Equipment section. Avoid clean up procedures that generate dust or result in water pollution. After
removal, scrub the contaminated area with detergent and flush thoroughly with water. Absorb wash liquid and
place in the disposable container.
Other Information: Notify local authorities, if required. Spills of this material do not need to be reported to the
National Response Center.
Section 7: HANDLING AND STORAGE
Handling
Avoid contact with skin, eyes and/or clothing. Minimize dust generation during handling and contact. Wash
thoroughly after handling and before eating, drinking, or smoking.
Storage
Store at room temperature in well ventilated area. Keep container closed when not in use. Product residue may
remain in empty container. Observe all label precautions until container is cleaned, reconditioned or destroyed.
Storage Hazards
Store away from oxidizers.
Section 8: EXPOSURE CONTROLS/PERSONAL PROTECTION
Exposure Guidelines
MES No Exposure limits established by OSHA or ACGIH
ACGIH - Particulated Not Otherwise Classified (PNOC)
Inhalable particulate (1989) TWA 10 mg/m3
Respirable particulate (1995) TWA 3 mg/m3
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Revision: B01; 04/25/06 Replaces Sheet Date: 10/18/04
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MATERIAL SAFETY DATA SHEET
Engineering Controls: Provide Local exhaust ventilation, process enclosures, and other forms or engineering
controls are the preferred means for controlling exposures. Facilities using or storing this material should be
equipped with an eyewash station and safety shower.
Eye/face Protection: Do not wear contact lenses when working with this substance. Avoid eye contact with this
material at all times. Wear chemical safety glasses with side shields or chemical safety goggles.
Skin Protection: Avoid skin contact with this material. Use appropriate chemical protective gloves when
handling.
Respiratory Protection: Use process enclosures, local exhaust ventilation, or other engineering controls to
control airborne levels below recommended exposure levels. If this is not possible, a respiratory protection
program that meets OSHA 1910.134 requirements must be followed. Contact the manufacturer of your
respiratory protection equipment for further information and/or recommendations.
General Hygiene Considerations: Showering and changing into street clothing after work is recommended.
Section 9: PHYSICAL AND CHEMICAL PROPERTIES
Color: White
Odor: None
Odor Threshold: None
Physical State: Solid
Molecular Formula: C6H13NO4S*H2O
Molecular Weight: 213.3
pH: 1.0%; 3.5 ?4.1
Freezing Point: ND
Melting Point: ND
Boiling Point: ND
Flash Point: None
Evaporation Rate: None
Flammability (solid, gas): NA
Upper Flammability Limit: None
Lower Flammability Limit: None
Vapor Pressure: ND
Vapor Density: ND
Specific Gravity: ND
Solubility (water): ND
Partition Coefficient (n-octanol/water): ND
Auto-ignition Temperature: ND
Percent Volatile, wt %: 0%
Volatile Organic Compound (VOC) content, et. %: <1%
Part Number: RES0113M ND = No Data NA = Not Applicable Page 4 of 8
Revision: B01; 04/25/06 Replaces Sheet Date: 10/18/04
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MATERIAL SAFETY DATA SHEET
Section 10: Stability and Reactivity
Stability: Stable under normal conditions of use.
Conditions to Avoid: ND
Incompatible Material: Incompatible with strong oxidizing agents.
Hazardous Decomposition Products: Combustion may produce CO, CO2, NO x, and/or SO x.
Possibility of Hazardous Reactions: Will not occur.
Section 11: Toxicology Information
Registry of the Toxic Effects of Chemical Substances (RTECS?
RTECS # QE3479500
Listed as: 4-Morpholineethanesulfonic acid
Only selected data is presented here. See actual entry in RTECS for complete information.
ACUTE EFFECTS
Oral LD50: >316 mg/kg (Bird (Quail))
Dermal LD50: ND
Inhalation: ND
Eye Irritation : ND
Skin Irritation: ND
Sensitization: Not expected to cause skin or respiratory sensitization based on similarities to
other tested materials of similar composition.
CHRONIC EFFECTS
Carcinogenicity: ND
Mutagenicity: ND
Reproductive Effects: ND
Developmental Effects: ND
Section 12: Ecological Information
Ecotoxicity: ND
Persistence/Degradability: ND
Bioaccumulation/Accumulation: ND
Mobility in Environment: ND
Section 13: Disposal Considerations
Disposal: Under RCRA, it is the responsibility of the user of the product to determine, at the time of
disposal, whether the product meets RCRA criteria for hazardous waste. Dispose of in
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Revision: B01; 04/25/06 Replaces Sheet Date: 10/18/04
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MATERIAL SAFETY DATA SHEET
accordance with federal, state and local regulations. Contact your local disposal service
provider(s) for appropriate method(s) of disposal.
Section 14: Transportation Information
U.S. Department of Transportation (U.S. DOT) Requirements
Proper Shipping Name: NOT REGULATED
Technical Name: MES
Hazard Class: NA UN/NA Code: NA
Packaging Group NA
Reportable Quantity: NA
Labels Required: NA
Marine Pollutant (49 CFR 172.101 Appendix B): NO
Emergency Response Guidebook Number: NA
Canadian TDG (ground)
Proper Shipping Description: See U.S. DOT
ICAO (air)
Proper Shipping Description: See U.S. DOT
IMDG (water)
Proper Shipping Description: See U.S. DOT
Section 15: Regulatory Information
INVENTORY STATUS
Inventory Status
United States (TSCA) MES (CAS# 4432-31-9 ?Non Hydrate version) listed. Hydrates of a listed non-
hydrate are exempt from listing.
Canada (DSL) All ingredients are on the inventory or exempt from listing.
European Union (EINECS) All ingredients are on the inventory or exempt from listing.
Japan (METI) All other ingredients are on the inventory or exempt from listing.
Philippines All other ingredients are on the inventory or exempt from listing.
South Korea (KECL) All ingredients are on the inventory or exempt from listing.
Australia (AICS) All ingredients are on the inventory or exempt from listing.
China All ingredients are on the inventory or exempt from listing.
Federal Regulations:
SARA Title III Rules
Section 311/312 Hazard Classes
Fire Hazard No
Reactive Hazard No
Release of Pressure No
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Revision: B01; 04/25/06 Replaces Sheet Date: 10/18/04
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MATERIAL SAFETY DATA SHEET
Acute Health Hazard No
Chronic Health Hazard No
Section 313 Toxic Chemicals
If this box is checked, this product contains EPCRA 313 chemical(s) subject to the
reporting requirements of Section 313 of the Emergency Planning and Community Right-
to-Know Act of 1986 (40 CFR 372). If you are unsure whether you are subject to
reporting requirements or need more information, call EPS's ECPRA Call Center at (800)
424-9346 or (703) 412-9810.
Component CAS # % by Wt.
None NA NA
Section 302 Extremely Hazardous Substances (EHS) / CERCLA Hazardous Substances
Ingredient CERCLA/SARA RQ SARA EHS TPQ
None NA NA
Other Federal Regulations:
Drug Precursor Regulations: Not Listed.
Essential Chemical by the Chemical Diversion and Trafficking Act of 1988: Not Listed.
Weapons Precursor Regulations: Not Listed.
State Regulations:
California: Based on available information this material does not contain any component(s) or
chemical(s) currently known to the State of California to cause cancer, birth defects or
reproductive harm at levels which would be subject to Proposition 65, California Safe
Drinking Water and Toxic Enforcement Act of 1986.
State HCS Programs:
Massachusetts: ND Pennsylvania: ND
Rhode Island: ND Washington: ND
New Jersey: ND Delaware: ND
Michigan: ND New York: ND
Minnesota: ND
International Regulations:
OEL=MAK
International Phrases
R - ND Not Determined
S - ND Not Determined
Canada (Additional Information):
WMIS Classification: ND
CEPA: ND
Canadian Domestic Substances List/Non-Domestic Substances List: ND
Product Registrations:
Japan: ND
Korea: ND
Finland: ND
Norway: ND
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Revision: B01; 04/25/06 Replaces Sheet Date: 10/18/04
Product Name: MES Validated on 4/25/06 9:28 AM
MATERIAL SAFETY DATA SHEET
Sweden: ND
Switzerland: ND
New Zealand: ND
Section 16: Other Information
NFPA?704 Ratings:
Health (H) Flammability (F) Reactivity ( R ) Special Hazards
- - - -
HMIS?Ratings:
Health (H) Flammability (F) Physical Hazard (PH) Personal Protection
Equipment (PPE)
1 1 0 E
NFPA is a registrated trademark of the National Fire Protection Association. HMIS is a registrated trademark of the National Paint
and Coating Association.
Prepared by: Research Organics, Inc., Environmental & Safety Department
Disclaimer:
The information contained in this document applies to this specific material as supplied. It does not relate to
use in combination with any other material or in any process. Research Organics, Inc. provides the information
contained herein in good faith but makes no representation as to its comprehensiveness or accuracy. Individuals
receiving this information must exercise their independent judgment in determining its appropriateness for a
particular purpose. Research Organics, Inc. makes no representations, or warranties, either expressed or
implied, of merchantability, fitness for a particular purpose with respect to the information refers. Accordingly,
Research Organics, Inc. will not be responsible for damages resulting from the use of reliance upon this
information. In no instance is any Research Organics, Inc. product offered for drug, food, food additive or
clinical use in humans. In some cases, the user of the product may be required to make notification or obtain
registration from a government agency, like the U.S. EPA, for certain application. It is the user of the product
responsibility to make notification or obtain registration before purchase and/or use.
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Revision: B01; 04/25/06 Replaces Sheet Date: 10/18/04
Product Name: MES Validated on 4/25/06 9:28 AM
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